Clinical trials: Ovarian Stimulation
IVF Treatment
Self-operated Endo-vaginal Telemonitoring (SOET), an Economic and Patient-empowered Method for Ovarian Stimulation for In-vitro Fertilization (IVF)
The SOET project introduces a new strategy for routine follow-up of follicle growth during the hormonal treatment phase of an in-vitro fertilization (IVF) treatment cycle.
- Trial name
- SOET (NCT01781143)
- Testing
- Perform Echo at home.
- Where
- 4 sites in Belgium
- Volunteers
- 121 people
- Sponsor
- University Hospital, Ghent
Infertility, Female, Ovarian Reserve
hCG Priming in Women With Low Ovarian Reserve
The aim of this trial is to examine the possible effects of hCG administration for eight weeks prior to IVF/ICSI in women with low ovarian reserve.
- Conditions
- Infertility, Female, Ovarian Reserve, In Vitro Fertilization
- Trial name
- NCT04643925
- Testing
- Ovitrelle
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
in Vitro Fertilization, Ovulation Induction
Trial Comparing Start Stimulation of Recombinant Follicle Stimulating Hormone (rFSH) on Cycle Day 2 Versus Cycle Day 5 in In Vitro Fertilization (IVF)
Background of the study: Milder stimulation protocols have the advantage of being less expensive and more patient-friendly. Moreover, recent evidence suggests that mild stimulation protocols lead to lower embryo aneuploidy rates…
- Trial name
- LITE (NCT00823472)
- Testing
- Mild stimulation
- Where
- 2 sites in Belgium, Netherlands
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Female Infertility
Phase IV Study to Evaluate the Efficacy and Safety of Fang Le Shu Compared to Guo Na Fen for Controlled Ovarian Stimulation in Infertile Women Undergoing in Vitro Fertilization-embryo Transfer (IVF-ET).
The aim of this randomized, open-label, active-controlled, parallel-group, multicenter, phase IV study is to assess the efficacy and safety of Fang Le Shu versus Guo Na Fen used for controlled ovarian stimulation in infertile…
- Trial name
- NCT06921395
- Testing
- Fang Le Shu (Follitrope), Guo Na Fen (Gonal-F)
- Where
- China
- Volunteers
- 248 people
- Sponsor
- LG Chem
Infertility
Diafert for Embryo Selection and Fertility Improvement
Prospective, single-center, single-blind, randomized, controlled, two-arm, interventional study.
- Trial name
- DESTINy (NCT02586272)
- Testing
- Daifert, Control Group
- Where
- Belgium
- Volunteers
- 61 people
- Sponsor
- Forest Laboratories
Pregnancy, Ovarian
Clinical and Live Birth Rates After Following Long Antagonist Protocol Versus Long Agonist Protocol
A prospective study of the evaluation of the clinical IVF (in vitro fertilization) results after following Long Antagonist protocol for Controlled Ovarian Stimulation (COS) versus following Long Agonist protocol
- Trial name
- NCT03693534
- Testing
- Clinical Pregnancy Rate
- Where
- Greece
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Assisting Nature
In Vitro Fertilization
Prediction of Ovarian Response
The purpose of this study is to evaluate if there is an association between the endocrine and ultrasonographic markers of ovarian reserve and the IVF outcome and to determine which markers contribute to the prediction of poor…
- Trial name
- NCT00557687
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- Aristotle University Of Thessaloniki
Infertility
A Dose-response Trial Using FE 999049 in Japanese Women Undergoing in Vitro Fertilisation (IVF) / Intracytoplasmic Sperm Injection (ICSI) Treatment
This trial investigates the effects of several doses of FE 999049 in Japanese women undergoing IVF/ICSI treatment.
- Trial name
- NCT02309671
- Testing
- FE 999049, follitropin beta
- Where
- Japan
- Volunteers
- 159 people
- Sponsor
- Ferring Pharmaceuticals
Female Infertility, Female Subfertility
Effects of Recombinant LH in Patients With Repeated Implantation Failure
Pregnancy rates fall dramatically in women after 35 years undergoing to IVF or ICSI. While ovarian aging obviously plays the major role in this phenomenon, over suppression of endogenous LH concentrations with GnRH agonists or…
- Trial name
- late-rLH (NCT03204253)
- Testing
- rFSH + r-LH in combination, rFSH alone
- Volunteers
- 60 people
- Sponsor
- University of Roma La Sapienza
Infertility
Efficacy and Safety of FE 999049 in Controlled Ovarian Stimulation in Japanese Women
To demonstrate non-inferiority of FE 999049 compared to FOLLISTIM with respect to number of oocytes retrieved in Japanese IVF/ICSI patients undergoing controlled ovarian stimulation.
- Trial name
- NCT03228680
- Testing
- Follitropin delta, Follitropin beta
- Where
- 17 sites in Japan
- Volunteers
- 373 people
- Sponsor
- Ferring Pharmaceuticals
Infertility
A Trial to Compare the Ovarian Response of REKOVELLE and GONAL-F in Conventional Dosing in Women Undergoing Controlled Ovarian Stimulation
Hormone preparations like REKOVELLE and GONAL-F are used to make the body produce multiple egg sacs, allowing more eggs to be collected from women undergoing infertility treatment.
- Trial name
- ADAPT-1 (NCT05263388)
- Testing
- REKOVELLE (Follitropin Delta), GONAL-F (Follitropin Alfa)
- Where
- 16 sites in Austria, France and 3 more
- Volunteers
- 302 people
- Sponsor
- Ferring Pharmaceuticals
IVF
Endometrial Preparation in Frozen Embryo Transfer Cycles
In order to get optimal pregnancy rates after frozen embryo transfer (FET), the embryo stage and endometrium should be synchronized.
- Trial name
- NCT06181305
- Testing
- estradiol valerate and letrozole, letrozole 2,5 mg tablet
- Where
- Egypt
- Volunteers
- 210 people
- Sponsor
- Rahem Fertility Center
In Vitro Fertilization
Follow-up Protocol on the Outcome of Frozen-thawed Embryo Transfer Cycles From Clinical Trial P05690 (P05711)
Clinical trial objective is to collect the outcome of Frozen-Thawed Embryo Transfer (FTET) cycles performed after the embryos are cryopreserved in the base study P05690 in order to estimate the cumulative pregnancy rate for each…
- Trial name
- NCT00702546
- Testing
- corifollitropin alfa, recFSH (follitropin alfa), gonadatropin releasing hormone (GnRH) antagonist ganirelix
- Volunteers
- 102 people
- Sponsor
- Organon and Co
Infertility
Type of Gonadotropin and Embryo Kinetics of Development
The study is proposed to determine the effect of three types of gonadotropins that are currently used in protocols of controlled ovarian stimulation in women undergoing in vitro fertilization techniques on the kinetics of…
- Trial name
- PEM-ESD (NCT02402192)
- Testing
- Corifollitropin alfa
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- IVI Madrid
Infertility
Comparison of the Accuracy and Reliability of AMH, FSH and AFC in Predicting Ovarian Response
Serum bio-markers have different prediction values for ovarian response during ovarian stimulation in-vitro fertilization
- Trial name
- AMH FSH AFC (NCT02173444)
- Testing
- Blood test
- Where
- Vietnam
- Volunteers
- 820 people
- Sponsor
- Vietnam National University
Infertility
Evaluation of Efficacy and Safety of Highly Purified Urofollitropin in Chinese Females Undergoing an Assisted Reproductive Technology (ART) Program
Evaluate the efficacy and safety of of Highly Purified Urofollitropin for Injection Compared to Recombinant Human Follitropin Alfa for Injection in Chinese Females Undergoing an Assisted Reproductive Technology (ART) Program.
- Trial name
- NCT01922193
- Testing
- Highly Purified Urofollitropin, Recombinant Human Follitropin Alfa
- Where
- 11 sites in China
- Volunteers
- 263 people
- Sponsor
- Ferring Pharmaceuticals
Epithelial Ovarian Cancer, Colony Stimulating Factors
Long-acting G-CSF for Febrile Neutropenia
This study aims to analyze the effects of long-acting granulocyte colony stimulating factor (G-CSF) on the prevention febrile neutropenia (FN) in epithelial ovarian cancer.
- Conditions
- Epithelial Ovarian Cancer, Colony Stimulating Factors, Febrile Neutropenia, Myelosuppression Adult
- Trial name
- NCT03740464
- Testing
- long-acting granulocyte colony stimulating factor, Short-term granulocyte colony stimulating factor
- Where
- China
- Volunteers
- 556 people
- Sponsor
- Lei Li
Infertility
Diafert for Embryo Selection and Fertility Improvement (DESTINy)
Prospective, single-center, single-blind, randomized, controlled, two-arm, interventional study.
- Trial name
- DESTINy (NCT02593513)
- Testing
- Daifert, Control Group
- Where
- Hungary
- Volunteers
- 108 people
- Sponsor
- Forest Laboratories
Ovarian Hyperstimulation Syndrome, Infertility, Female
Dual Trigger" in IVF Patients at High Risk of Ovarian Hyper Stimulation Syndrome
The present study aims to evaluate whether the use of a "dual trigger" can improve IVF outcomes, compared to GnRH agonist (GnRH-a) alone, in patients at high risk of OHSS undergoing a freeze-all cycle.
- Trial name
- NCT05638529
- Testing
- Pregnyl (1,500) IU, 1.5 mL of normal saline
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Mount Sinai Hospital, Canada
Infertility
An Efficacy and Safety Study of Corifollitropin Alfa (MK-8962) in Contrast to Recombinant FSH for Use in Controlled Ovarian Stimulation of Indian Women (P07056, Also Known as MK-8962-029)
This study, conducted in India, will be recruiting women participants who are between the ages of 18 and 42, and who have an indication for controlled ovarian stimulation (COS), but have not yet undergone in-vitro fertilization…
- Trial name
- NCT01599494
- Testing
- MK-8962, recFSH, Ganirelix
- Sponsor
- Organon and Co