Clinical trials: Ovary Cyst
Polycystic Ovary Syndrome
The Effect of Atorvastatin on Androgens, Glucose Metabolism and Inflammation in Polycystic Ovary Syndrome (PCOS) Women
This is a placebo controlled trial investigating the effect of 6 months atorvastatin 20mg/day therapy on androgens, glucose metabolism and inflammatory markers in women with PCOS.
- Trial name
- NCT01072097
- Testing
- Atorvastatin
- Where
- Finland
- Volunteers
- 30 people
- Sponsor
- University of Oulu
Polycystic Ovary Syndrome, Obesity
Two Different Dietary Interventions for Girls With Polycystic Ovary Syndrome
This study was conducted to evaluate the efficacy of the MEtabolic Syndrome REduction in NAvarra (RESMENA) diet versus a control diet based on American Heart Association (AHA) recommendations for the treatment of PCOS in…
- Conditions
- Polycystic Ovary Syndrome, Obesity, Androgen; Hypersecretion, Diet, Healthy
- Trial name
- NCT05768724
- Testing
- intervention diet, control diet
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Gazi University
Polycystic Ovary Syndrome, Anovulation
Effect of Vitamin D on Ovulation Rate in Women With Polycystic Ovary Syndrome
This is a randomized double-blind controlled trial on the effect of vitamin D supplementation to assess the ovulation rate of women with polycystic ovary syndrome (PCOS) and other reproductive, endocrine and metabolic outcomes…
- Trial name
- NCT04650880
- Testing
- Vitamin D
- Where
- 3 sites in Hong Kong
- Volunteers
- 220 people
- Sponsor
- The University of Hong Kong
Infertility, Female, Polycystic Ovarian Syndrome
Optimising Preconceptual Health in Subfertile PCOS Patients Using a Lifestyle Modification Program
Patients will be randomly assigned to a group where they undergo a 12-week lifestyle modification program prior to their fertility treatment, or a group where they are entitled to start their fertility treatment without prior…
- Conditions
- Infertility, Female, Polycystic Ovarian Syndrome, Lifestyle
- Trial name
- NCT05084274
- Testing
- Lifestyle program
- Where
- Belgium
- Volunteers
- 19 people
- Sponsor
- Universitair Ziekenhuis Brussel
Polycystic Ovary Syndrome
Effects of Interleukin-1 Receptor Antagonism on Hyperandrogenemia in Women With Polycystic Ovary Syndrome
A prospective, interventional, open-label, single-arm, proof-of-concept study: 18 women with Polycystic Ovary Syndrome (PCOS) will be treated with 100 mg of Anakinra/Kineret® for 4 weeks.
- Trial name
- FertIL (NCT03578497)
- Testing
- IL-1 receptor antagonist Anakinra
- Where
- Switzerland
- Volunteers
- 18 people
- Sponsor
- University Hospital, Basel, Switzerland
Polycystic Ovary Syndrome
The Effect of Cinnamon Extract on Insulin Resistance Parameters in Polycystic Ovary Syndrome: A Pilot Study
The purpose of this study is to determine whether oral cinnamon extract are effective in reducing insulin resistance parameters in women with polycystic ovary syndrome.
- Trial name
- NCT00331279
- Testing
- Oral Cinnamon Extract
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Columbia University
Hyperandrogenism, Polycystic Ovary Syndrome
Does Spironolactone Normalize Sleep-wake Luteinizing Hormone Pulse Frequency in Pubertal Girls With Hyperandrogenism?
The purpose of this study is to determine if, in mid- to late pubertal girls with hyperandrogenism (HA), androgen-receptor blockade (spironolactone) alone normalizes sleep-wake luteinizing hormone (LH) pulse frequency (primary…
- Conditions
- Hyperandrogenism, Polycystic Ovary Syndrome, Puberty
- Trial name
- CBS010 (NCT04723862)
- Testing
- Spironolactone
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Polycystic Ovary Syndrome (PCOS) Women
Health-related Quality of Life of Women with Polycystic Ovary Syndrome At Sohag University Hospital
It is well-established that PCOS women suffer from anxiety, depression, and markedly reduced QoL ,but There has not yet been a nationally representative study to evaluate the PCOS health related Qol and factors affecting it among…
- Trial name
- NCT06832735
- Where
- Egypt
- Volunteers
- 352 people
- Sponsor
- Sohag University
Polycystic Ovary Syndrome
Acupuncture and Gonadotropin-releasing Hormone Pulse Generator and Stress Axis in Polycystic Ovary Syndrome
Hypothesis The overall hypothesis is that non-obese (BMI <30) women with PCOS have high luteinising hormone (LH) and cortisol pulse frequency and amplitude and that repeated low-frequency EA restore these alterations and induce…
- Trial name
- PCOSLFEA (NCT00921492)
- Testing
- Low-frequency electro-acupuncture (EA), Meeting a therapist - attention control
- Where
- Sweden
- Volunteers
- 28 people
- Sponsor
- Göteborg University
Polycystic Ovary Syndrome, Urine Albumin \(UAlb\)
Urine Albumin/Creatinine Ratio and Renal Function Differences in Phenotypes of Polycystic Ovary Syndrome.
Since there are different metabolic effects in different phenotypes of polycystic ovary syndrome (PCOS); in this study; the investigators aimed to investigate whether there is a difference between glomerular filtration rate…
- Conditions
- Polycystic Ovary Syndrome, Urine Albumin \(UAlb\), Urine Creatinine \(UCr\), Glomerular Filtration Rate
- Trial name
- NCT07441811
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- Uşak University
Endometriosis, Polycystic Ovary Syndrome
Determination of the Incidence of Endometriosis and or Adenomyosis in Patients Diagnosed With Polycystic Ovary Syndrome, or the Incidence of Polycystic Ovary Syndrome in Patients Diagnosed With Endometriosis and or Adenomyosis
The study was designed as a multicenter, prospective cross-sectional cohort study. The research population will consist of patients under the age of 40, diagnosed with endometriosis and/or adenomyosis and polycystic ovary…
- Conditions
- Endometriosis, Polycystic Ovary Syndrome, Adenomyosis
- Trial name
- NCT04916171
- Testing
- incidence
- Where
- Turkey (Türkiye)
- Volunteers
- 2,450 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Infertility
Evaluation of Anti-mullerian Hormone(AMH) Levels as a Predictive Factor of Response to Weight Loss Treatment in Obese Infertile Women With Poly Cystic Ovary(PCOS)
This study is a prospective before \& after clinical trial to compare the basal and 3 months after diet anti-mullerian hormone levels between responders and non-responders to weight loss diet in obese infertile women with PCOS…
- Trial name
- NCT01792362
- Testing
- Weight loss diet
- Where
- Iran
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Royan Institute
Polycystic Ovarian Syndrome (PCOS), Infertility
Effect of NAE on Polycystic Ovarian Syndrome (PCOS)
Polycystic Ovarian Syndrome (PCOS) is a multifaceted endocrine metabolic condition impacting about 5-10% of women throughout their reproductive lifespan.
- Conditions
- Polycystic Ovarian Syndrome (PCOS), Infertility, Metabolic Disorders
- Trial name
- NAE-PCOS (NCT07603505)
- Testing
- Herbal Formulation, Metformin XR, Metformin 750 mg and herbal formulation 500 mg
- Where
- Pakistan
- Volunteers
- 116 people
- Sponsor
- Jinnah Sindh Medical University
Polycystic Ovary Syndrome
Study of Pharmacodynamics of LIK066 in Overweight and Obese Women With Polycystic Ovary Syndrome
The purpose of the study was to evaluate whether LIK066 can be developed for the treatment of polycystic ovary syndrome (PCOS) in overweight and obese women.
- Trial name
- PCOS (NCT03152591)
- Testing
- LIK066
- Where
- 5 sites in United States, Germany
- Volunteers
- 29 people
- Sponsor
- Novartis Pharmaceuticals
Polycystic Ovarian Syndrome
Endometrial Effects of Metformin Action in Women With Polycystic Ovarian Syndrome (PCOS)
The investigators aim is to conduct a prospective un-blinded pilot study of premenopausal women diagnosed with Polycystic Ovarian Syndrome (PCOS), defined using criteria developed at the 1990 NICHD conference on PCOS, undergoing…
- Trial name
- NCT01070160
- Testing
- Endometrin (progesterone 100mg vaginal inserts), Metformin
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Yale University
Pre Diabetes, Polycystic Ovary Syndrome
Liraglutide 3mg (Saxenda) on Weight, Body Composition, Hormonal and Metabolic Parameters in Obese Women With PCOS
There is a growing need to develop pharmacologic interventions to improve metabolic function in women with polycystic ovary syndrome (PCOS).
- Conditions
- Pre Diabetes, Polycystic Ovary Syndrome, Obesity Android
- Trial name
- SAXAPCOS (NCT03480022)
- Testing
- Liraglutide Pen Injector [Saxenda]
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- Woman's
Polycystic Ovary Syndrome, Endothelial Dysfunction
Metformin+ Drospirenone/ethinylestradiol30µg and Flow-mediated Dilation in Polycystic Ovary Syndrome
The purpose of this study is to assess the effects of ethinylestradiol 30µg-drospirenone combined with metformin and weight loss by means of dietary intervention on the indices of endothelial dysfunction (i.e.
- Trial name
- NCT01459445
- Testing
- Metformin, Ethinylestradiol 30µg-Drospirenone
- Where
- Romania
- Volunteers
- 26 people
- Sponsor
- Iuliu Hatieganu University of Medicine and Pharmacy
Endometrioma
Laparoscopic Ovarian Cystectomy of Endometrioma vs Deroofing and Ovarian Reserve
The purpose of this study is to evaluate the impact of laparoscopic ovarian cystectomy versus laparoscopic cyst deroofing on ovarian reserve measured by serum levels of anti mullerian hormone and antral follicle count in patients…
- Trial name
- NCT01808170
- Testing
- Laparoscopic ovarian cystectomy, laparoscopic cyst deroofing
- Where
- Egypt
- Volunteers
- 122 people
- Sponsor
- Ain Shams University
Polycystic Ovarian Syndrome (PCOS)
BRCC36 and Telomerase Levels in Women With Polycystic Ovary Syndrome
This prospective observational case-control study evaluated serum BRCC36 and telomerase (TE) levels in women with polycystic ovary syndrome (PCOS) and healthy controls. Women aged 18-43 years were included.
- Trial name
- NCT07849166
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University
Polycystic Ovarian Syndrome, Insulin Resistance
Evaluation of a Combination of a Plant Extract and a Probiotic on Glucidic Metabolism in Women With PCOS and High Insulin Levels
The aim of the present study is to evaluate the effect of the combination of a plant extract (BSL_EP044) and Lactobacillus BSL_PS6 on parameters of the glucidic metabolism, anthropometric parameters, hormonal levels and the…
- Trial name
- NCT04029805
- Testing
- Combination of a plant extract (BSL_EP044) and Lactobacillus BSL_PS6
- Where
- Spain
- Volunteers
- 34 people
- Sponsor
- Biosearch S.A.
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