Clinical trials: Ovary Cyst
Polycystic Ovary Syndrome
Effect of Weight & Insulin Sensitivity on Reproductive Function in PCOS: Studies in Skeletal Muscle & Adipose
The overall objective of this ancillary study is to obtain skeletal muscle and subcutaneous adipose tissue biopsies from women with polycystic ovary syndrome enrolled in the PULSE Study (NCT01482286).
- Trial name
- PULSE-A (NCT01775176)
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Pennington Biomedical Research Center
Polycystic Ovary Syndrome, Anovulation
Inositol Supplementation to Treat PCOS (INSUPP-PCOS)
To determine if Inositol, a dietary supplement, will improve ovarian and adrenal androgen excess in women with Polycystic Ovarian Syndrome(PCOS).
- Conditions
- Polycystic Ovary Syndrome, Anovulation, Hyperandrogenism, Insulin Resistance
- Trial name
- INSUPP-PCOS (NCT03864068)
- Testing
- Inositol
- Where
- 2 sites in United States
- Volunteers
- 154 people
- Sponsor
- Milton S. Hershey Medical Center
Polycystic Ovary Syndrome
the Effect of Diane-35 Pretreatment on In-vitro Fertilization Outcome for Patients With Polycystic Ovary Syndrome
Polycystic Ovary Syndrome is the most common endocrine disorder in women, is estimated to affect more than 5% of the population and is associated with chronically elevated serum androgen concentrations.Evidence suggests that…
- Trial name
- NCT01752270
- Testing
- Diane-35 pretreatment
- Where
- 2 sites in China
- Volunteers
- 100 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Polycystic Ovary Syndrome
Clinical and Biochemical Presentation of Polycystic Ovary Syndrome in Different Age Group
To study the clinical and biochemical characteristics women with polycystic ovary syndrome (PCOS) in different aged groups.
- Trial name
- NCT01350895
- Where
- Taiwan
- Volunteers
- 781 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University WanFang Hospital
Polycystic Ovary Syndrome (PCOS), Anovulatory Infertility
Clomiphene Citrate Alone Versus Clomiphene Plus Metformin as First Line Approach for the Treatment of Anovulation in Infertile Patients With Polycystic Ovary Syndrome
This study will compare the effectiveness of clomiphene citrate alone with clomiphene citrate combined with metformin for treating anovulation and infertility in women with polycystic ovary syndrome (PCOS).
- Trial name
- CC-MET PCOS T (NCT07872501)
- Testing
- Clomiphane citrate + Metformin, clomiphene citrate alone
- Where
- Pakistan
- Volunteers
- 218 people
- Sponsor
- Independent University Hospital, Pakistan
Polycystic Ovary Syndrome
Letrozole or Laparoscopic Ovarian Diathermy for Women With CC Resistant Polycystic Ovary Syndrome.
The purpose of this study is to compare and determine the efficacy of letrozole administration to that of laparoscopic ovarian diathermy (LOD) in infertile women with Polycystic ovary syndrome(PCOS)not responding to treatment…
- Trial name
- NCT00956267
- Testing
- Letrozole, Laparoscopic ovarian diathermy (LOD)
- Where
- Egypt
- Volunteers
- 260 people
- Sponsor
- Mansoura University
PCOS (Polycystic Ovary Syndrome)
Development and Clinical Application of ApoC3 Protein as a Predictive Biomarker for Insulin Resistance in Polycystic Ovary Syndrome
Polycystic Ovary Syndrome (PCOS) is the most common reproductive endocrine disorder causing infertility and miscarriage in women.
- Trial name
- NCT07739953
- Testing
- observational study
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Guangdong Women and Children Hospital
Polycystic Ovary Syndrome
Effect of UC Versus EA on Sex Hormones in Obese Infertile Patients With PCOs
The aim of this study is to determine the difference between the effect of Ultrasound Cavitation and Elctroacupuncture on sex hormones in obese infertile patients with poly cystic ovarian syndrome ………………………………………………………………………
- Trial name
- NCT04875312
- Testing
- Ultrasound cavitation in group A, Electro acupuncture in group B
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mohamed Abdel Hamid elgaedy
Polycystic Ovary Syndrome
Effect of High Testosterone on Sleep-associated Slowing of Follicular Luteinizing Hormone (LH) Frequency in Polycystic Ovary Syndrome
The purpose of this study is to determine whether a testosterone receptor blocker (flutamide) will normalize sleep-wake luteinizing hormone pulse frequency relationships in women with polycystic ovary syndrome.
- Trial name
- CRM004 (NCT00930228)
- Testing
- Flutamide
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Polycystic Ovary Syndrome, Hyperinsulinism
Randomized Study of Decreased Hyperinsulinemia on the Ovulatory Response to Clomiphene Citrate in Women With Polycystic Ovary Syndrome
OBJECTIVES: I. Determine whether reduction of serum insulin levels by metformin increases ovulatory response to clomiphene citrate in women with polycystic ovary syndrome.
- Trial name
- NCT00005104
- Testing
- clomiphene citrate, metformin
- Where
- 6 sites in United States, Italy
- Volunteers
- 99 people
- Sponsor
- National Center for Research Resources (NCRR)
Polycystic Ovary Syndrome
Mediterranean Diet as Treatment for Normal Weight Women With PCOS
Polycystic ovary syndrome (PCOS) is the most common endocrinopathy of reproductive-aged women characterized by chronic anovulation, hyperandrogenism and insulin resistance.
- Trial name
- NCT02396264
- Testing
- mediterranean diet, normocaloric diet
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera OO.RR. S. Giovanni di Dio e Ruggi D'Aragona
Polycystic Ovary Syndrome
Clinical、metabolomics and the Study of Intestinal Flora of Jinfeng Pills in the Treatment of Polycystic Ovary Syndrome
The goal of this clinical trial is to compare the clinical effect of Jinfeng Pill and Diane-35 in patients with PCOS. The main questions it aims to answer are: a.
- Trial name
- NCT06823830
- Testing
- Jinfeng Pill
- Where
- China
- Volunteers
- 105 people
- Sponsor
- Peking Union Medical College Hospital
Infertility, Polycystic Ovary Syndrome (PCOS)
Metformin in High Responder Polycystic Ovary Syndrome (PCOS) Patients Undergoing IVF Cycles
The use of metformin pre-treatment and co-administration was recently proposed in infertile women affected by polycystic ovary syndrome (PCOS) treated with gonadotropins.
- Trial name
- NCT01233206
- Testing
- Metformin
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- University Magna Graecia
PCOS, Reproductive Age
Adipokines in Polycystic Ovary Syndrome
The aim of the study is to compare the concentrations of leptin, resistin, and omentin-1 in women across three research groups: those with polycystic ovary syndrome without insulin resistance, those with polycystic ovary syndrome…
- Trial name
- NCT06793072
- Testing
- Leptin concentration in blood serum, Resistin concentration in blood serum, Omentin-1 concentration in blood serum
- Where
- Poland
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Jagiellonian University
Obesity, Type 2 Diabetes
Body Composition, Glucose Metabolism, Insulin Resistance and Gene Expression in Muscle Cells in Healthy Overweight Women
In this study, we will clarify the degree of insulin resistance and characterise muscle glucose metabolism and gene expression in a group of overweight healthy women.
- Conditions
- Obesity, Type 2 Diabetes, Polycystic Ovary Syndrome
- Trial name
- NCT00145392
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Type2 Diabetes, Polycystic Ovary Syndrome
Myocardial Pathological Changes in Patients of Type 2 Diabetes With or Without PCOS Using Cardiac Magnetic Resonance
The study is prepared to use CMR technology for early screening of myocardial lesions in 561 age-matched women with type 2 diabetes without PCOS, with PCOS without type 2 diabetes and with type 2 diabetes combined with PCOS…
- Trial name
- NCT04805853
- Where
- China
- Volunteers
- 561 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
Polycystic Ovarian Syndrome, Hyperandrogenism
Hemocoagulation and Lipoperoxidation in Women Using Combined Oral Contraceptives, Correction by Antioxidants
We investigate parameters of hemocoagulation and lipoperoxidation in women using combined oral contraceptives with antiandrogenic activity (containing drospirenone with 20 or 30 mcg ethinylestradiol; or cyproterone acetate)…
- Conditions
- Polycystic Ovarian Syndrome, Hyperandrogenism, Menstrual Irregularities
- Trial name
- NCT02027337
- Testing
- 20 mcg ethinylestradiol /3 mg drospirenone, 20 mcg ethinylestradiol/3 mg drospirenone and Selmevit, 30 mcg ethinylestradiol/3 mg drospirenone
- Where
- Russia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Tyumen State Medical University
Polycystic Ovary Syndrome, Insulin Resistance
Dissecting the IMpact of 11-OXygenated and Classic Androgens on Skeletal Muscle Insulin Sensitivity (DIMOXIS)
Androgen excess is the cardinal biochemical feature of polycystic ovary syndrome (PCOS). Serum testosterone correlates with insulin resistance in PCOS, however, there is an urgent need to improve our understanding of the…
- Conditions
- Polycystic Ovary Syndrome, Insulin Resistance, Androgen; Hypersecretion, Endocrine System Diseases
- Trial name
- DIMOXIS (NCT05263557)
- Testing
- Dehydroepiandrosterone (DHEA), 11-ketoandrostenedione (11KA4)
- Where
- Ireland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Royal College of Surgeons, Ireland
Polycystic Ovary Syndrome (PCOS)
Phenotyping of Patients With Polycystic Ovary Syndrome
Polycystic ovary syndrome (PCOS) is the leading endocrine disorder of the reproductive system, affecting 10 to 13% of women of childbearing age.
- Trial name
- SOPK (NCT07339930)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Strasbourg, France
Polycystic Ovary Syndrome
71A/G HSD17B5 SNP and Effects of Oral Contraceptive Pill in PCOS Women
An association of the single nucleotide polymorphism (SNP) in the promoter gene that codify for 17b-HSD5 enzyme (71A>G) with polycystic ovary syndrome (PCOS) and hyperandrogenemia has been suggested in previous studies.
- Trial name
- 17b-ACO (NCT01372293)
- Testing
- oral contraceptive pill
- Volunteers
- 49 people
- Sponsor
- Federal University of Rio Grande do Sul
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