Clinical trials: Ovary Cyst
Polycystic Ovary Syndrome
The Use Of AMH for the Discrimination of Polycystic and Multicystic Ovaries in Nonhyperandrogenic Patients
AMH is a member of the transforming growth factor family. It is produced by the granulosa cells from 36th weeks of pregnancy.Ovarian granulosa cells are the only source of the antimüllerian hormone.
- Trial name
- NCT01878955
- Testing
- AMH level difference between patient with PCOS and multicystic ovaries.
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Fibromyalgia, PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries
Evaluation of Fibromyalgia Frequency and Pain Parameters in Women With Polycystic Ovary Syndrome
The primary objective was to determine the prevalence of fibromyalgia in women with PCOS and to examine the relationship between fibromyalgia and psychological status (depression and anxiety).
- Trial name
- NCT07189247
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Ufuk University
Polycystic Ovary Syndrome, Polycystic Ovary Syndrome (PCOS) Women
Metabolic and Hormonal Parameters in Women With Polyendocrine Metabolic Ovarian Syndrome
Polyendocrine Metabolic Ovarian Syndrome (PMOS) is a common endocrine and metabolic disorder associated with insulin resistance, hyperandrogenism, and an increased risk of long-term metabolic complications.
- Conditions
- Polycystic Ovary Syndrome, Polycystic Ovary Syndrome (PCOS) Women, Fetuin-A, Serum Biomarkers
- Trial name
- PMOS-FR (NCT07844785)
- Testing
- Blood and Saliva Biomarker Assessment
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Istinye University
Obesity, Polycystic Ovary Syndrome
Treatment of Obesity With Topiramate in Patients With Polycystic Ovary Syndrome
Treatment of obesity related to Polycystic Ovary Syndrome with topiramate or placebo to assess improvement of clinical and laboratory parameters after 6 months of follow-up
- Conditions
- Obesity, Polycystic Ovary Syndrome, Hyperandrogenism
- Trial name
- NCT04453306
- Testing
- Topiramate
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Polycystic Ovarian Syndrome (PCOS)
Effect of Coenzyme Q10 Administration on Polycystic Ovary Syndrome
The goal of this clinical trial is to determine the effects of coenzyme Q10 supplementation on oxidative stress, inflammation and hyperandrogenism in women with polycystic ovary syndrome.
- Trial name
- PCOS (NCT06659406)
- Testing
- Coenzyme Q10
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- University of Faisalabad
Early Detection of Ovarian Cancer
Screening for Ovarian Malignancy
Ovarian cancer is the second most common gynecologic malignancy. In 2008, it was the seventh leading cause of cancer deaths in women worldwide.
- Trial name
- NCT06348784
- Testing
- Assesment of Different NEoplasias in the adenexa model, Risk of malignancy index, Histopathologic examination
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams Maternity Hospital
Polycystic Ovary Syndrome
Short Term Ketogenic Diet in Polycictic Ovary Syndrome
Polycystic ovary syndrome (PCOS) is one of the most common health problems in women of reproductive age, characterized by increased androgen levels, impaired ovulatory functions, and polycystic ovaries.
- Trial name
- NCT06469255
- Testing
- Diet Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Istanbul Bilgi University
Pregnancy, Polycystic Ovary Syndrome
Acupuncture and Clomiphene Citrate on Live Birth in Anovulatory Women With Polycystic Ovary Syndrome
The objectives of the present trial are to test the following three hypotheses in anovulatory women with PCOS: 1. Acupuncture protocol 1 plus CC (Arm A) is more likely to result in live birth than acupuncture protocol 2 combined…
- Conditions
- Pregnancy, Polycystic Ovary Syndrome, Infertility
- Trial name
- PCOSAct (NCT01573858)
- Testing
- Acupuncture treatment 1, Acupuncture treatment 2, CC
- Where
- 25 sites in China
- Volunteers
- 1,000 people
- Sponsor
- Heilongjiang University of Chinese Medicine
Polycystic Ovary Syndrome
Semaglutide vs Metformin in Polycystic Ovary Syndrome (PCOS)
The goal of this clinical trial is to compare the effect of Semaglutide and metformin on weight loss in obese women with Polycystic Ovarian Syndrome (PCOS) over a 28-week treatment period.
- Trial name
- NCT05646199
- Testing
- Metformin, Semaglutide Injectable Product
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- University of Hull
Polycystic Ovarian Syndrome (PCOS), Irregular Menstrual Cycles
Effect of a Commonly Used Antibiotic, Doxycycline, in Women With Polycystic Ovarian Syndrome
The purpose of this study is to study the effect of a commonly used antibiotic, doxycycline, on the production of ovarian hormones and menstrual cycles in women with Polycystic Ovarian Syndrome (PCOS).
- Conditions
- Polycystic Ovarian Syndrome (PCOS), Irregular Menstrual Cycles, Androgen Excess
- Trial name
- MI-PCOS (NCT01788215)
- Testing
- doxycycline, Sugar Pill
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Rochester
PCOS (Polycystic Ovary Syndrome)
Clinical Research Cohort for Polycystic Ovary Syndrome
Polycystic Ovary Syndrome (PCOS) is a multifactorial metabolic-endocrine disorder characterized by hyperandrogenism, ovulatory dysfunction, and polycystic ovarian morphology.
- Trial name
- PCOS (NCT07739940)
- Where
- China
- Volunteers
- 420 people
- Sponsor
- Guangdong Women and Children Hospital
Polycystic Ovary Syndrome
Effects of Fenofibrate on Metabolic and Reproductive Parameters in Polycystic Ovary Syndrome
This is a prospective randomized, double-blind placebo-controlled trial of 6 months' duration evaluating the effect of fenofibrate (200 mg/day) in females with polycystic ovary syndrome and mild hypertriglyceridemia.
- Trial name
- NCT00884819
- Testing
- Fenofibrate
- Where
- Canada
- Volunteers
- 4 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Polycystic Ovary Syndrome (PCOS), Myo-inositol
Myo-Inositol and D-Chiro-Inositol for Menstrual Irregularities and Hormone Changes in Women With Polycystic Ovarian Syndrome
The goal of this clinical trial is to determine whether a combination of myo-inositol (MI) and D-chiro-inositol (DCI) with folic acid is more effective than placebo (Folic acid alone) in improving menstrual irregularities and…
- Conditions
- Polycystic Ovary Syndrome (PCOS), Myo-inositol, D-chiro-inositol
- Trial name
- NCT07701525
- Testing
- Myo-Inositol and D-Chiro-Inositol Combination Therapy
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Nishtar Medical University
Infertility, Polycystic Ovarian Syndrome
HRT Versus MOS for Endometrial Preparation Prior to FET in PCOS Patients
Evaluation of endometrial preparation using either hormonal therapy or ovarian stimulation prior to frozen-thawed embryo transfer (FET) in patients with polycystic ovarian syndrome (PCOS)
- Trial name
- NCT02273791
- Testing
- Estradiol valerate, Sequential Clomiphene citrate and Gonadotropin
- Where
- 2 sites in Egypt
- Volunteers
- 126 people
- Sponsor
- Mansoura University
Polycystic Ovary Syndrome
Effect of Meal Composition on Postprandial Testosterone Concentration in Women With Polycystic Ovary Syndrome
The primary objective is to determine if meals of different fat and fiber content affect postprandial plasma testosterone concentration in women with polycystic ovary syndrome.
- Trial name
- NCT00455338
- Testing
- Meal Composition
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Polycystic Ovary Syndrome, PCOS
Randomized Controlled Trial of Combined Letrozole and Clomid (CLC II) Versus Letrozole Alone for Women With Anovulation
This study evaluates the addition of clomiphene citrate (CC) to letrozole for the treatment of infertility in women with polycystic ovary syndrome across a course of two treatment cycles with stair step dosing of letrozole…
- Conditions
- Polycystic Ovary Syndrome, PCOS, Infertility
- Trial name
- CLC II (NCT05206448)
- Testing
- Letrozole, Clomiphene Citrate
- Where
- 4 sites in United States
- Volunteers
- 190 people
- Sponsor
- Rachel Mejia
Polycystic Ovary Syndrome, Weight Gain
Empagliflozin vs Metformin on Metabolic Dysfunction in Polycystic Ovary Syndrome With or Without Comorbidity or Multimorbidity
this is open labelled randomize control trial among women with PCOS. PCOS, an endocrine condition, affects 5%-15% of premenopausal women.
- Conditions
- Polycystic Ovary Syndrome, Weight Gain, HbA1c
- Trial name
- NCT06140108
- Testing
- Empagliflozin 10 MG, MetFORMIN 500 Mg Oral Tablet
- Where
- Pakistan
- Volunteers
- 70 people
- Sponsor
- SINA Health Education and Welfare Trust
Polycystic Ovary Syndrome
Aerobic Training With and Without Resistance Training in Polycystic Ovarian Syndrome
Polycystic ovary syndrome (PCOS) characterized by a chronic disorder in ovulation along with hyperandrogenism has become one of the most common endocrine disorders in women of reproductive age with an estimated 5%-15% prevalence.
- Trial name
- NCT06198348
- Testing
- Aerobic Exercise, Aerobic Exercises with Resistance training
- Where
- Pakistan
- Volunteers
- 22 people
- Sponsor
- Riphah International University
PCOS (Polycystic Ovary Syndrome)
Health-Related Quality of Life and Metabolic Outcomes in PCOS
The primary outcome of interest is change in PCOS health-related quality of life, while the secondary outcome of interest is change in adiposity, cardiometabolic, and inflammation biomarkers.
- Trial name
- NCT07571915
- Testing
- Intervention Group
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Polycystic Ovary Syndrome (PCOS)
Steroid Profiles in PCOS and Effect of OCP Treatment
This prospective observational study investigates the changes in serum steroid intermediates assessed by liquid chromatography-mass spectrometry (LC-MS/MS) in adolescents and young women with polycystic ovary syndrome (PCOS)…
- Trial name
- PCOSLCMS (NCT07161440)
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Istanbul University
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