Clinical trials: Over Cancer
Men, Age Problem
Register of Therapeutical Patients Over 60 Years
Register for the study of the prevalence and burden of diseases, risk factors and outcomes of hospitalizations in older age groups in the countries of Eurasia.
- Conditions
- Men, Age Problem, Therapeutic Alliance
- Trial name
- ASCLEPIUS (NCT04295057)
- Testing
- Non-intervention
- Where
- Russia
- Volunteers
- 12,000 people, healthy volunteers welcome
- Sponsor
- Eurasian Association of Therapists
Cervical Cancer
Decreasing Over Screening and Treatment of Cervical Precancers in Young Women
The goal of this study is to prevent over screening and over treatment of young women for cervical precancers, which can result in psychological distress and has been associated with future risk of premature deliveries.
- Trial name
- NCT02270021
- Testing
- Provider Mobile Application (ProvAPP), ProvAPP + Patient Educational Tool (Tab)
- Where
- 2 sites in United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Pancreas Cancer, Pancreas Neoplasm, Benign
Endoscopic Ultrasound Guided Tissue Sampling (The SharkBITE Study)
This study compares the diagnostic performance of Endoscopic ultrasound (EUS) guided fine needle aspiration and EUS guided core biopsy (SharkCore) in patients with a solid pancreatic mass.
- Conditions
- Pancreas Cancer, Pancreas Neoplasm, Benign, Chronic Pancreatitis, Pancreas Adenocarcinoma
- Trial name
- SharkBITE (NCT03532347)
- Testing
- EUS-FNA needle (Beacon)
- Where
- United Kingdom
- Volunteers
- 108 people
- Sponsor
- Newcastle-upon-Tyne Hospitals NHS Trust
Neuroblastoma
Combination Chemotherapy in Treating Young Patients Who Are Undergoing Surgery and an Autologous Bone Marrow Transplant for Disseminated Neuroblastoma
RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT00365755
- Testing
- carboplatin, cisplatin, cyclophosphamide
- Sponsor
- Children's Cancer and Leukaemia Group
Cancer, With Caregiver Support Time
French Validation of an Interview Guide to Cancer Announcement : the Psycho Oncology Basic Documentation
Validation of the PO-BADO in its short and long versions that need a standardized validation process with the inclusion of 450 Patients
- Conditions
- Cancer, With Caregiver Support Time, 18 Years and Over
- Trial name
- PO-BADO (NCT02874001)
- Volunteers
- 252 people
- Sponsor
- Institut Bergonié
Lung Neoplasms
GILT Docetaxel - Non-Small Cell Lung Cancer
Primary Objective: To compare response rate between genotypic groups and control group. Secondary Objective: To determine the safety, time to treatment failure and survival in control and genotypic arms.
- Trial name
- NCT00174629
- Testing
- Docetaxel/DDP, docetaxel/gemcitabine
- Where
- 3 sites in Germany, Spain and 1 more
- Volunteers
- 449 people
- Sponsor
- Sanofi
Mantle Cell Lymphoma
Lenalidomide, Bendamustine and Rituximab as First-line Therapy for Patients Over 65 Years With Mantle Cell Lymphoma.
In phase I: Establishing maximally tolerated dose of lenalidomide in combination with bendamustine and rituximab. In phase II: Evaluation of progression free survival with treatment with lenalidomide, bendamustine and rituximab
- Trial name
- LENA-BERIT (NCT00963534)
- Testing
- lenalidomide, bendamustine, rituximab
- Where
- 17 sites in Denmark, Finland and 2 more
- Volunteers
- 51 people
- Sponsor
- Lund University Hospital
Head and Neck Neoplasms, Carcinoma, Squamous Cell
BIBW 2992 (Afatinib) in Head & Neck Cancer
The primary objective of this study is to explore the efficacy of BIBW 2992 compared with cetuximab (Erbitux) in patients with metastatic or recurrent head and neck cancer after failure of platinum-containing therapy.
- Trial name
- NCT00514943
- Testing
- BIBW 2992, Cetuximab
- Where
- 36 sites in United States, Belgium and 2 more
- Volunteers
- 124 people
- Sponsor
- Boehringer Ingelheim
Haemophilia A (Moderate or Severe)
Study to Provide Continued Access to Treatment for Patients Completing a Previous Trial With Efanesoctocog Alfa
This is a multinational, prospective, open-label, roll-over study in patients with haemophilia A, ≥6 years of age, who have completed participation in any of the parental studies with efanesoctocog alfa; XTEND-ed study…
- Trial name
- LIBERTY (NCT06716814)
- Testing
- Efanesoctocog alfa
- Where
- 20 sites in Bulgaria, France and 5 more
- Volunteers
- 89 people
- Sponsor
- Swedish Orphan Biovitrum
Infratentorial Neoplasms, Hyperventilation
The Effect of Different Ventilation Strategies on Cerebral Oxygenation Using Near Infrared Spectroscopy (NIRS) in Pediatrics Undergoing Posterior Fossa Tumor Surgery
The aim of this study is to evaluate the changes of cerebral oxygen saturation during hyperventilation and normo-ventilation (using near-infrared spectroscopy) in pediatrics undergoing posterior fossa tumor resection.
- Conditions
- Infratentorial Neoplasms, Hyperventilation, Craniotomy
- Trial name
- NCT04232059
- Testing
- cerebral oximetry
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Kasr El Aini Hospital
Hepatocellular Carcinoma (HCC), Solitary Mass
Ten-Year Outcomes of Operable Solitary Hepatocellular Carcinoma Patients: Impact of Tumor Size Over 6.5 cm and Microvascular Invasion
The goal of this study is to evaualte the impact of tumor size and microvascular invasion among patients with solitary hepatocellualr carcinoma and post operation.
- Trial name
- NCT06628661
- Testing
- Surgery for HCC larger than 6.5 cm, Surgery for HCC larger than 2 cm
- Where
- Taiwan
- Volunteers
- 3,000 people
- Sponsor
- Chang Gung Memorial Hospital
Kidney Failure, Chronic
Observational Study to Evaluate the Time to Achieving the Maintenance Dose of Zemplar® (Paricalcitol Injection) in the Treatment of Patients Suffering From End-stage Renal Disease and Severe Over-reactivity of the Parathyroid Glands
This observational study will evaluate the clinical benefit of Zemplar (paricalcitol injection) in daily routine practice in end-stage renal disease patients with severe over-reactivity of parathyroid glands.
- Trial name
- NCT01273597
- Where
- 11 sites in Hungary
- Volunteers
- 60 people
- Sponsor
- AbbVie (prior sponsor, Abbott)
Cancer, Venous Thromboembolism
WAVe Study - Weight Adjusted Dalteparin for Patients Over 90 kg With Acute Cancer Associated Venous Thromboembolism
Cancer patients that develop blood clots are treated with low molecular weight heparin injections (LMWH). One kind of these LMWHs, dalteparin, has its dose determined based on a patient's weight using a formula of 200…
- Conditions
- Cancer, Venous Thromboembolism, Obesity
- Trial name
- WAVe (NCT03297359)
- Testing
- Dalteparin
- Where
- 5 sites in Canada
- Volunteers
- 92 people
- Sponsor
- Ottawa Hospital Research Institute
Male Hypogonadism
Study to Compare DITEST to Testosterone Undecanoate in Adult Men With Hypogonadism
DITEST is an oral formulation of native testosterone for the treatment of androgen deficiency in men. The study was a Phase 1 clinical study in hypogonadal men, defined according to FDA and Endocrine Society Guidelines, designed…
- Trial name
- NCT02966652
- Testing
- DITEST, Testosterone undecanoate
- Where
- United Kingdom
- Volunteers
- 25 people
- Sponsor
- Neurocrine UK Limited
Polycystic Ovary Syndrome
Trial With Metformin in Women With Polycystic Ovary Syndrome
The investigators wanted to elucidate the effects of metformin in Polycystic Ovary Syndrome (PCOS) by performing a randomized, double-blinded, placebo-controlled cross-over study.
- Trial name
- NCT02280057
- Testing
- Metformin
- Where
- Denmark
- Volunteers
- 56 people
- Sponsor
- Herning Hospital
Mucinous Adenocarcinoma of the Colon, Mucinous Adenocarcinoma of the Rectum
Telomere Length in Predicting Toxicity in Older Patients With Stage III-IV Colorectal Cancer Undergoing Chemotherapy
This pilot research trial studies telomere length in predicting toxicity in older patients with stage III-IV colorectal cancer undergoing chemotherapy.
- Conditions
- Mucinous Adenocarcinoma of the Colon, Mucinous Adenocarcinoma of the Rectum, Signet Ring Adenocarcinoma of the Colon, Signet Ring Adenocarcinoma of the Rectum
- Trial name
- NCT01934179
- Testing
- cytology specimen collection procedure, laboratory biomarker analysis, questionnaire administration
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Fox Chase Cancer Center
Progressive Desmoids Tumors
PAZOPANIB Efficacy and Tolerance in Desmoids Tumors
Desmoids tumors are benign soft tissues tumors characterized by aggressiveness and potential local recurrence. There is a female predominance with a sex ratio of 2/1 and median age at diagnosis is about 30 years.
- Trial name
- DESMOPAZ (NCT01876082)
- Testing
- PAZOPANIB treatment, Active Comparator: Vinblastine and Methotrexate
- Where
- France
- Volunteers
- 72 people
- Sponsor
- Institut Bergonié
Pain, Cancer
A Efficacy and Safety Trial of Controlled Release (CR) Morphine in Cancer Patients
The purpose of the study is to determine the effect of Egalet® Morphine once daily compared to MST Continus twice daily on pain intensity and use of rescue medication for break through pain after 2 weeks of treatment in patients…
- Trial name
- NCT00446069
- Testing
- Morphine Sulphate
- Where
- 8 sites in Lithuania, Poland
- Volunteers
- 36 people
- Sponsor
- Egalet Ltd
Breast Cancer
An Observational Study of Adherence to Anastrozole in Early Breast Cancer Treatment
The purpose of this study is to describe adherence to anastrozole treatment current practice: cases where anastrozole treatment was halted ( timescale and causes) and estimate the proportion of postmenopausal women with early…
- Trial name
- NCT00737009
- Where
- 3 sites in Vietnam
- Volunteers
- 259 people
- Sponsor
- AstraZeneca
Health-related Quality of Life
The Impact of Supervision by a Health Care Professional on Quality of Life Questionnaire
Effect of supervision on scoring and completion on Quality of Life Questionnaire
- Trial name
- IMSUP (NCT06490393)
- Testing
- Questionnaires
- Where
- Switzerland
- Volunteers
- 200 people
- Sponsor
- St. Claraspital AG