Clinical trials: Over Weight
Obesity, Vascular Risk
Efficacy of Triticum Aestivum Over Vascular Function in Mexican Obese Patients
This study aims to evaluate the efficacy of Triticum aestivum as a treatment for improving the vascular function in Mexican obese patients.
- Trial name
- NCT06950138
- Testing
- Triticum aestivum, calcined magnesia
- Where
- Mexico
- Volunteers
- 20 people
- Sponsor
- Coordinación de Investigación en Salud, Mexico
Overweight, Walking
Comparison Of Normal Walking Vs Brisk Walking In Over-Weight Adults
The goal of this clinical trial is to see the comparison of normal walking vs brisk walking on body fat, hypertension, diabetes, and level of happiness in over-weight adults.
- Trial name
- NCT05854797
- Testing
- Normal Walking, Brisk Walking
- Where
- Pakistan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Type 2 Diabetes
Effects of Exenatide on Glycemic Control and Weight in Continuous Subcutaneous Insulin Infusion (CSII) Type 2 Treated Patients With Type 2 Diabetes
The purpose of this study is to determine whether exenatide is effective to improve glycemic control among type 2 diabetic patients treated by insulin pump therapy.
- Trial name
- EXEPUMP (NCT01140893)
- Testing
- Exenatide
- Where
- 3 sites in France
- Volunteers
- 110 people
- Sponsor
- University Hospital, Caen
Cancer, Rectum
Converted Laparoscopic Resection of Upper Rectal Carcinoma T1-4 N0-1 in Obese Patients.
Background: laparoscopic resection (LAR) is a safe approach and widely used for rectal cancer after neoadjuvant chemo-radiotherapy, but short term and oncological outcome for converted cases to open surgery (cLAR), may be…
- Trial name
- NCT04401787
- Testing
- Anterior resection for upper rectal cancer in obese
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Zagazig University
End-Stage Kidney Disease, Hemodialysis
Effect of Sodium Rinsing Fluid on Blood Pressure and Interdialytic Weight Change in Hemodialysis Patients
This is a prospective, randomized, double-blind, parallel group trial to assess the efficacy and safety of intravenous dextrose 5% solution compare with normal saline (standard care) in wash back procedure during haemodialysis in…
- Trial name
- NSD5 (NCT02590081)
- Testing
- Dextrose 5%, normal saline
- Where
- 15 sites in Malaysia
- Volunteers
- 434 people
- Sponsor
- Penang Hospital, Malaysia
Obesity
APPETITE: linguAl PYY3-36 on aPpEtite and acuTe Energy InTakE
A double-blind, cross-over, placebo-controlled, proof-of-concept study using oral peptide YY3-36 solution to investigate the mechanistic role of lingual PYY in regulating appetite, energy intake and food preference in people with…
- Trial name
- APPETITE (NCT05110664)
- Testing
- PYY (3-36) Peptide, Placibo
- Volunteers
- 40 people
- Sponsor
- University College, London
Prader-Willi Syndrome, Obesity
Double-Blind, Placebo Controlled, Phase 3 Trial of ZGN-440 (Beloranib) in Obese Subjects With Prader-Willi Syndrome
The purpose of this study is to evaluate efficacy and safety of ZGN-440 (beloranib) in obese adolescent and adult subjects with Prader-Willi Syndrome.
- Trial name
- bestPWS (NCT02179151)
- Testing
- ZGN-440 for Injectable Suspension
- Where
- 15 sites in United States
- Volunteers
- 108 people
- Sponsor
- Zafgen, Inc.
Overweight
Effects of Sucrose Added Blind to the Diet Over Eight Weeks on Body Mass and Weight in Men
Background: Sugar intake, especially in liquid, correlates with obesity. Yet, whether it is a special cause of obesity is less clear. Few experimental studies exist.
- Trial name
- NCT04804397
- Testing
- Sucrose
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Hull
Frailty, Obesity
Slow Gait Speed as an Indicator of Overweight, Dynapenic Obesity and Sarcopenic Obesity in Elderly People in the Community
The goal of this observational study is to evaluate the relationship of gait speed with dynapenic or sarcopenic obesity in community-dwelling older people.
- Conditions
- Frailty, Obesity, Sarcopenia, Sarcopenic Obesity
- Trial name
- SGSF (NCT06413030)
- Testing
- 10 Meter Walk Test
- Where
- Chile
- Volunteers
- 383 people, healthy volunteers welcome
- Sponsor
- University of Americas - Chili
Glucose Intolerance, Obesity
Clinical Trial to Assess the Effects of Candesartan on the Carbohydrate Metabolism of Obese Subjects
Hypothesis: The use of candesartan 16-32 mg/d for 6 months improves the carbohydrate metabolism, and decreases the plasmatic levels of adipocytokines and oxidative stress markers, in non diabetic, non hypertensive subjects with…
- Trial name
- ARAMIA (NCT00319202)
- Testing
- Candesartan
- Where
- Colombia
- Volunteers
- 56 people
- Sponsor
- Fundación Cardiovascular de Colombia
Normoglycemic, Normal Body Weight
A Study of the Effect of Oats on Post Prandial Glucose Response
The objectives are to assess the effects of high viscosity vs. medium and low viscosity oat β-glucan on post-prandial glycemic response in healthy adult participants.
- Trial name
- NCT02651597
- Testing
- Oatmeal
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Osteoarthritis, Knee
The Effect of Exercise on Serum Levels of Collagen and Proteoglycan in Patients With Knee Osteoarthritis
The aim of EFEX-OA-02 is to explore how running, cycling, exercise simulation and resting acutely influence collagen and proteoglycan homeostasis in OA, as reflected by changes in collagen and proteoglycan levels in urine and…
- Trial name
- EFEX-OA-02 (NCT04542668)
- Testing
- Cycling then running, Running then cycling, Inotropy
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Nordic Bioscience A/S
Overweight and Obesity
The Food Effect on Pharmacokinetics of DA-302168S
This study will be conducted to determine the effect of food on the pharmacokinetics characteristic of DA-302168S following administration of a DA-302168S tablet with and without a high-fat meal.
- Trial name
- DA168 (NCT06534346)
- Testing
- 15 mg DA-302168S tablet
- Where
- China
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Chendu DIAO Pharmaceutical Group CO., LTD.
Obesity
Effect of Daily Intake of SATIOSTAT Over 6 Weeks on Weight Loss, Glucose Tolerance, Gastrointestinal Tolerance and Gut Microbiota.
SATIOSTAT is a composition comprising a specific dietary fibre component (a mixture of hydrocolloids with excellent safety profiles and a long history of use in humans) and a lipid component (long-chain fatty acids).
- Trial name
- NCT02956369
- Testing
- Control, SATIOSTAT
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Over Weight, Obesity
Safety and Performance Evaluation of Tulip Device in Healthy Overweight and Obese Volunteers
The study will assess the safety and performance of an intragastric auto-inflating and degradable balloon
- Trial name
- NCT01753609
- Testing
- Tulip capsule
- Where
- Israel
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Tulip Medical Ltd.
Overweight
Lifestyle Intervention Program in Overweight Medical Students
This study will be a randomized cross-over design over the course of 2 academic years. 40 subjects -20 overweight women and 20 over weight men will be recruited.
- Trial name
- NCT03636581
- Testing
- Lifestyle counseling
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- New York Institute of Technology
Overweight
The Effect of a Propionate Colon Release Form on ad Libitum Eating and Appetite Perception
The present study aims to investigate the effect of a standardized liquid breakfast containing a food grade propionate colon release form on ad libitum eating and appetite perception in healthy overweight humans using a…
- Trial name
- METABIOTIC (NCT04019951)
- Testing
- Ca-propionate 1 g, Ca-propionate 3 g
- Where
- Canada
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- dsm-firmenich Switzerland AG
Weight Loss, Weight Change, Body
Does the Timing of When High Intensity Intermittent Exercise is Undertaken Matter?
The participants will visit the laboratory on 3 occasions, once for a preliminary visit and a further two occasions to complete experimental trials in a randomised order.
- Conditions
- Weight Loss, Weight Change, Body, Nutritional and Metabolic Disease
- Trial name
- HIIE (NCT04122209)
- Testing
- HIIE-First, Continuous-First
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Manchester Metropolitan University
Cachexia, Anorexia
Pharmacokinetics of Megace F and Megace OS Under Fasting and Fed Conditions in Healthy Male Volunteers
Phase I study of Megace F will be conducted to investigate pharmacokinetics and safety compared to Megace OS. Phase I study divided into 3 parts written as belows.
- Trial name
- MGF (NCT01397214)
- Testing
- Megace F, Megace OS
- Where
- South Korea
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Boryung Pharmaceutical Co., Ltd
Overweight, Obesity
A Study to Evaluate How VI-0521 Affect Psychomotor Performance in Healthy Overweight and Obese Subjects.
The purpose of this study is to determine how VI-0521 affect speed and reaction time on specific tasks that require eye and hand coordination, compared to placebo.
- Trial name
- NCT00806260
- Testing
- VI-0521, Alcohol
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- VIVUS LLC