Clinical trials: Overeating
Prader-Willi Syndrome, Hyperphagia
Oxytocin vs. Placebo for the Treatment Hyperphagia in Children and Adolescents With Prader-Willi Syndrome
The investigators propose a randomized double-blind 8 week treatment trial of intranasal oxytocin (IN-OXT) vs. placebo in 24 subjects aged 5 to 18 years with PWS in order to assess IN-OXT's affect on (1) Eating behaviors (2)…
- Trial name
- OXT-PWS (NCT02629991)
- Testing
- Intranasal Oxytocin (IN-OXT)
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Montefiore Medical Center
Bulimia Nervosa, Body Dysmorphic Disorder
An Open Label Trial of Memantine in the Treatment of Bulimia Nervosa and Body Dysmorphic Disorder
The primary objective of this 13-week clinical trial is to test the hypothesis that treatment with Memantine will significantly improve the symptoms of those suffering from either bulimia nervosa, purging type or suffering from…
- Trial name
- NCT01038128
- Testing
- Memantine
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Mclean Hospital
Parenteral Nutrition, Blood Stream Infection
Three-Chamber Bags Retrospective Study in Spain
The primary study objective is to assess the rates of blood stream infection (BSI) from the use of Three-Chamber Bags (e.g., SmofKabiven®, Kabiven®, others) compared to Hospital Compounded Bags (HCBs) in patients requiring…
- Trial name
- NCT03284398
- Where
- 2 sites in Spain
- Volunteers
- 3,723 people
- Sponsor
- Fresenius Kabi
Self-regulation, Binge Eating
Using Mobile Technology to Improve Self-Regulation
This study will evaluate the degree to which engaging targets produces a desired change in medical regimen adherence (across 4-week interventions) and health behavior among smokers (n=50) and overweight/obese persons with binge…
- Conditions
- Self-regulation, Binge Eating, Smoking
- Trial name
- NCT03774433
- Testing
- Laddr
- Where
- United States
- Volunteers
- 114 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Short Bowel Syndrome
Study of Teduglutide Effectiveness in Parenteral Nutrition (PN)-Dependent Short Bowel Syndrome (SBS) Subjects
Teduglutide is an investigative medicine being evaluated as a possible treatment for people with parenteral nutrition (PN) dependent Short Bowel Syndrome (SBS). Teduglutide is similar to a protein the body makes.
- Trial name
- STEPS (NCT00798967)
- Testing
- teduglutide
- Where
- 35 sites in United States, Canada and 8 more
- Volunteers
- 86 people
- Sponsor
- Shire
Cholestasis, Jaundice, Obstructive
SMOFlipid to Lessen the Severity of Neonatal Cholestasis
Parenteral nutrition (PN) provides intravenous nutritional supplementation for infants unable to absorb adequate enteral nutrients secondary to insufficient intestinal length or function.
- Trial name
- NCT02721277
- Testing
- SMOFlipid
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- University of Florida
Binge Eating Disorder
Weight Loss Treatment for Veterans With Binge Eating
This study aims to adapt and test a cognitive behavioral therapy (CBT) treatment that can be administered concurrently with the Veteran's Health Administration (VHA) MOVE! weight management program for Veterans with DSM-5 Binge…
- Trial name
- NCT03234881
- Testing
- MOVE!, MOVE!+CBT
- Where
- 2 sites in United States
- Volunteers
- 109 people
- Sponsor
- VA Office of Research and Development
Critical Illness
The Energy Dose Study
The investigators have designed this single-center Randomized Clinical Trial (RCT) to prospectively compare, for the first time, the clinical efficacy of different energy doses in intensive care unit (ICU) patients requiring…
- Trial name
- NCT01369147
- Testing
- Parenteral Nutrition, Propofol, Clevidipine
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Emory University
Bulimia Nervosa, Bulimia; Atypical
Reward Re-Training: A New Treatment to Address Reward Imbalance During the COVID-19 Pandemic
In the current study, the investigators will revise our existing 10-session group RRT treatment manual to specifically address the challenges in building social support and enhancing both momentary and sustained reward during the…
- Conditions
- Bulimia Nervosa, Bulimia; Atypical, Binge Eating, Binge-Eating Disorder
- Trial name
- NCT04661410
- Testing
- Reward Re-Training, Supportive Therapy
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Drexel University
Cholestasis, Cholestasis of Parenteral Nutrition
Omegaven as Alternative Parenteral Fat Nutrition
To provide Omegaven® as a compassionate treatment for critically ill infants with parenteral nutrition associated cholestasis
- Trial name
- NCT03662282
- Testing
- Omegaven
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of South Florida
Deglutition Disorders
Comparison of Outcomes Between Parenteral and Enteral Nutrition
Short-term outcomes of parenteral and enteral nutrition for patients unable to eat normally were compared and analyzed.
- Trial name
- NCT02512224
- Testing
- Parenteral nutrition, Enteral nutrition
- Volunteers
- 5,824 people
- Sponsor
- Tokyo University
Impulsivity, Compulsive Overeating
tDCS for Impulsivity and Compulsivity in Obesity
Even when they know it can improve health, many individuals with loss of control eating struggle when they are trying to make and sustain new health habits for weight loss and maintenance of weight loss.
- Conditions
- Impulsivity, Compulsive Overeating, Obesity
- Trial name
- NCT04405089
- Testing
- Device: Active Transcranial Direct Current Stimulation (tDCS) coupled with cognitive training
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Minneapolis Veterans Affairs Medical Center
Parenteral Nutrition (No Primary Condition Studied)
Dosing Study of Amino Acids in Seriously Ill Patients
The purpose of this study is to determine the best rate of infusion of amino acids (15% CLINISOL - sulfite-free (Amino Acid) Injection) for nutrition in subjects with with stages II to IVB head and neck cancer.
- Trial name
- NCT01923480
- Testing
- 15% CLINISOL - Sulfite-free (Amino Acid) Injection
- Where
- 2 sites in United States
- Volunteers
- 16 people
- Sponsor
- Baxter Healthcare Corporation
Bulimia
Effect of a CCK-1R Agonist on Food Intake in Humans
The ultimate aim of this study is to test the hypothesis that the oral cholecystokinin (CCK) agonist GSKI181771X will reduce the size of a binge meal among individuals with Bulimia Nervosa. The study will be conducted in phases.
- Trial name
- GSK (NCT00600743)
- Testing
- GSKI181771X (CCK-1R agonist), Instructions to binge eat, Instructions to eat normally
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Short Bowel Syndrome
Safety and Efficacy Study of Teduglutide in Subjects With Short Bowel Syndrome Who Completed Protocol CL0600-004 (NCT00081458)
The purpose of this clinical study is to evaluate the long-term safety and efficacy of daily administration of teduglutide.
- Trial name
- NCT00172185
- Testing
- teduglutide 0.05 mg/kg/d, teduglutide 0.10 mg/kg/d
- Where
- 21 sites in United States, Belgium and 6 more
- Volunteers
- 65 people
- Sponsor
- Shire
Prematurity
The Effect of Lipid Emulsions on Free Fatty Acids and Free Bilirubin in Premature Newborns
The goal of this research study is to compare the levels of free fatty acids and free bilirubin between two intravenous lipid emulsion products in premature newborns.
- Trial name
- NCT03857646
- Testing
- Intralipid, 20% Intravenous Emulsion, Soybean oil Medium-chain triglycerides Olive oil Fish Oil (SMOF) lipid
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- The University of Texas Health Science Center, Houston
Binge Eating, Type 2 Diabetes
FoodSteps for Binge Eating & Food Insecurity
The purpose of this study is to conduct a pilot trial of a mobile intervention that targets binge eating and weight-related behaviors, to determine the feasibility, acceptability, and preliminary efficacy of the intervention…
- Conditions
- Binge Eating, Type 2 Diabetes, Food Insecurity
- Trial name
- NCT06348251
- Testing
- FoodSteps
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Northwestern University
Obesity, Binge Eating
Treatment of Binge Eating in Obese Patients in Primary Care
This study will test the effectiveness of two empirically-supported but distinct treatments for recurrent binge eating in obese patients: 1) Cognitive Behavior Therapy, using a pure self-help approach and 2) sibutramine, an…
- Trial name
- NCT00537810
- Testing
- Sibutramine, Self-help CBT + Sibutramine
- Where
- 3 sites in United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Yale University
Alcohol; Use, Problem, Stress
A Behavioral Activation Intervention Administered in a College Freshman Orientation Course
The transition from high school to college is a developmentally sensitive period that is high risk for escalations in alcohol use.
- Conditions
- Alcohol; Use, Problem, Stress, Binge Eating, Depression
- Trial name
- NCT04038190
- Testing
- behavioral activation
- Where
- United States
- Volunteers
- 572 people, healthy volunteers welcome
- Sponsor
- University of Kansas
Anorexia Nervosa/Bulimia, Anorexia in Adolescence
Oral Naltrexone In Pediatric Eating Disorders
The objective of this study is to evaluate the effectiveness of oral naltrexone tablets in pediatric and adolescent eating disorders, in particular anorexia nervosa and bulimia nervosa, as compared to placebo.
- Conditions
- Anorexia Nervosa/Bulimia, Anorexia in Adolescence, Anorexia Nervosa, Atypical, Anorexia Nervosa, Binge Eating/Purging Type
- Trial name
- ONPED (NCT05073679)
- Testing
- Naltrexone Hydrochloride, Control
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Rosemary Claire Roden