Clinical trials: Overfed
Obese, Diabetes Mellitus, Type 2
Investigating Effects of BOTOX on Weight Loss and Glucose Tolerance in Obese, Type 2 Diabetic Subjects
The investigators will recruit obese subjects with pre-diabetes or type 2 diabetes for the proposed clinical study for 5 visits.
- Trial name
- NCT03991299
- Testing
- Botox 200 UNT Injection
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Vanderbilt University Medical Center
Childhood Obesity
Testing Digital Technologies to Help Families Build Healthy Habits
The current study is a randomized pilot trial to test the feasibility of a psychoeducational virtual reality experience to increase motivation for behavior change among children with overweight or obesity.
- Trial name
- NCT04845568
- Testing
- Virtual Reality Experience
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Washington University School of Medicine
Body Weight, Body Weight Changes
Online Family Dyadic Skills Training for Black Adults in Behavioral Weight Loss Program
The purpose of this research study is to test the feasibility and acceptability of an interactive counselor -led online family skills training as part of a behavioral weight loss program for Black Adults.
- Conditions
- Body Weight, Body Weight Changes, Obesity, Overweight and Obesity
- Trial name
- TEAM+ (NCT05981508)
- Testing
- Together, Eating and Activity, Matter Plus (TEAM+) Online, Together, Eating and Activity, Matter Plus (TEAM+) In-Person
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Obesity, Arthritis
Desflurane or Propofol Anesthesia in Elderly Obese Patients Undergoing Total Knee Replacement
You are invited to participate in a research study assessing your mental status in the first days after your surgery and how you will be doing in the 2 years following the surgery.
- Trial name
- NCT01270620
- Testing
- propofol, Desflurane
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Pedro Paulo Tanaka
Childhood Obesity
Summer Harvest Adventure: A Garden-based Obesity Prevention Program for Children Residing in Low-resource Communities
The objective of this study is to implement and test the efficacy of the "Summer Harvest Adventure," a comprehensive garden-based behavioral, social, and environmental intervention for children (ages 8-11 years) residing in…
- Trial name
- SHA (NCT05367674)
- Testing
- Summer Harvest Adventure, My Summer Plate (MSP)
- Where
- United States
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Pregnancy Related, Obesity
Misoprostol Dosing in BMI Greater Than 30
The investigators are performing a randomized controlled-trial investigating if 50mcg (compared to 25 mcg) of vaginal misoprostol reduces the time from induction start to delivery in obese women.
- Conditions
- Pregnancy Related, Obesity, Labor Onset and Length Abnormalities
- Trial name
- MD30 RCT (NCT05262738)
- Testing
- 50 Micrograms Vaginal Misoprostol (Intervention), 25 Micrograms Vaginal Misoprostol (Control)
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- University of Texas at Austin
Obesity, Overweight
Efficacy and Safety Trial to Evaluate the Effect of SCH 497079 on Weight in Obese and Overweight Participants (Study P05483)(COMPLETED)
The purpose of this study is to evaluate the effect of SCH 497079 on weight in obese and overweight participants. The primary measure of effectiveness is the change in body weight during treatment.
- Conditions
- Obesity, Overweight, Body Weight
- Trial name
- NCT00642993
- Testing
- SCH 497079
- Volunteers
- 401 people
- Sponsor
- Merck Sharp & Dohme LLC
Metabolic Syndrome, Dyslipidemia
Impact of Consumption of Beta-glucans on the Intestinal Microbiota and Glucose and Lipid Metabolism
The purpose of this study is to investigate if daily consumption of barley beta-glucans effect lipid and glucose metabolism and alter intestinal microbiota composition in participants with metabolic syndrome or with high risk for…
- Conditions
- Metabolic Syndrome, Dyslipidemia, Obesity, Abdominal, Hyperglycemia
- Trial name
- NCT02041104
- Testing
- Bread with added beta-glucans
- Where
- 3 sites in Slovenia
- Volunteers
- 51 people
- Sponsor
- Mlinotest Zivilska Industrija d.d.
Obesity Hypoventilation Syndrome
AVAPS-AE Efficacy Study
The purpose of this study is to evaluate the feasibility of using of the Average Volume Assured Pressure Support (AVAPS-AE) mode versus Continuous Positive Airway Pressure (CPAP) and bilevel pressure support ventilation (PSV)…
- Trial name
- NCT01368614
- Testing
- AVAPS-AE Mode of Therapy, Respironics OnmiLab BiPAP S mode, Respironics OmniLab Advanced CPAP mode
- Where
- 2 sites in United States
- Volunteers
- 90 people
- Sponsor
- Philips Respironics
Obesity
Reducing Health Disparities in Childhood Obesity
In this study, we will address cost barriers to participating in summer programs and hypothesize this will lead to marked improvements in children's obesogenic behaviors and a reduction in excessive, unhealthy weight gain over…
- Trial name
- NCT04072549
- Testing
- Free Summer Programming
- Where
- 2 sites in United States
- Volunteers
- 651 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Obesity
A Preliminary Comparison of the Blood Levels of Medications in Obese Subjects Compared to Post-Gastric Bypass Subjects
The purpose of this study is to determine the difference, if any, in the area under the sertraline plasma level time curve (AUC) between patients who are nine to fifteen months post Roux-en-Y Bariatric Surgery and control…
- Trial name
- NCT01015976
- Testing
- bariatric surgery, control
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Neuropsychiatric Research Institute, Fargo, North Dakota
Overweight, Obesity
Dissemination of the Look Ahead Weight Management Treatment in the Military
Purpose: This study aims to take the procedural and research-based lessons learned from a pilot weight loss intervention (IRB # 13-02563-XP), conducted by The University of Tennessee Health Science Center in 2013, and apply them…
- Trial name
- FITBLUE (NCT02063178)
- Testing
- Phone-based sessions (28 total) on a structured schedule, Phone-based sessions upon request, Weight self-monitoring
- Where
- United States
- Volunteers
- 248 people
- Sponsor
- University of Tennessee
Metabolic Syndrome, Metabolic Endotoxemia
Alleviation Of Metabolic Endotoxemia In Adults With Metabolic Syndrome With Milk Fat Globule Membrane
Metabolic syndrome (MetS) adults (n = 24; 18-65 y) will be enrolled to complete a 2-arm, double-blind, randomized controlled, crossover trial.
- Trial name
- NCT03860584
- Testing
- MFGM-enriched full-fat dairy milk, Soy phospholipid/lecithin milk
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Ohio State University
Loss-of-control Eating, Obesity/Overweight
Pharmacological and Behavioral Treatment After Bariatric Surgery: Medication Change for Non-Responders (Stage 2b)
This study will test the effectiveness of lisdexamfetamine medication as a treatment for loss-of-control eating and weight following bariatric surgery.
- Trial name
- NCT04599504
- Testing
- Lisdexamfetamine Dimesylate (Medication)
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Yale University
Healthy, Obesity
Mitochondrial Function in Circulating Cells and Muscle Tissue
The main goal of this project is to determine whether mitochondrial function in circulating cells is related to that measured in the muscle fibers of the same subjects.
- Conditions
- Healthy, Obesity, Insulin Sensitivity, Women
- Trial name
- MitoWomen (NCT02700698)
- Where
- 2 sites in United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Weight Gain, Healthy Subjects
Dietary Essential Fatty Acid Regulation of Omega-3 HUFA Metabolism; Satiety and Body Composition
Background: Rates of obesity have increased dramatically in recent decades, and researchers are investigating how changes in diets and physical activity have contributed to this increase.
- Conditions
- Weight Gain, Healthy Subjects, Obesity, Women
- Trial name
- NCT01251887
- Testing
- Linoleic Acid, Docosahexaenoic Acid, Eicosapentaenoic Acid
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Obesity, Hypertension
A Randomized Clinical Trial To Study Losartan On Endothelial Dysfunction and Insulin Resistance In Obese Patients
The main purposes of this study are to find out if the study drug losartan (Cozaar) or placebo ("sugar pill") has an effect on insulin sensitivity (how your body responds to insulin) and to measure the effect of the study drug…
- Conditions
- Obesity, Hypertension, Hyperglycemia
- Trial name
- NCT00675987
- Testing
- losartan
- Where
- 9 sites in United States
- Volunteers
- 53 people
- Sponsor
- Brigham and Women's Hospital
Obesity, Overweight
A Maintenance Program for the Be Fit Employee Wellness Program
This research study is being done: 1) to determine if the MGH Be Fit program helps employees to change their nutrition and exercise habits and lower their risk for chronic diseases, such as heart disease and diabetes and 2) to…
- Trial name
- NCT00707577
- Testing
- Internet-based maintenance program
- Where
- United States
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Overweight, Obesity
A Study to Compare Two Different Forms of PF-07081532 in Adults Who Are Overweight or Obese
The purpose of this study is to compare the amount of PF-07081532 in blood after taking two different forms of PF-07081532. This study is seeking participants who are at least 18 years of age and are overweight and/or obese.
- Trial name
- NCT05677867
- Testing
- Formulation A (PF-07081532 20 mg plus 60 mg), Formulation B (PF-07081532 80 mg)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Pfizer
Overweight
Phase 2 Study to Evaluate Safety and Efficacy of RM-493 in Obese Participants
The purpose of this study is to evaluate the effects of RM-493 on mean percent body weight loss, and other weight loss parameters as well as Pharmacokinetic (PK) profile, and ambulatory blood pressure in obese participants.
- Trial name
- NCT01749137
- Testing
- Setmelanotide
- Where
- 6 sites in United States
- Volunteers
- 74 people
- Sponsor
- Rhythm Pharmaceuticals, Inc.