Clinical trials: Overuse Injuries
Carpal Tunnel Syndrome
Ultrasound-Guided 5% Dextrose Injection for Carpal Tunnel Syndrome
This study was a prospective randomized double-blind clinical trial conducted at the Physical Medicine and Rehabilitation Clinic of a local research and training hospital in Turkey from October 2023 and May 2024.
- Trial name
- NCT06349265
- Testing
- Carpal Tunnel Hydrodissection with %5 dextrose in water injection
- Where
- Turkey (Türkiye)
- Volunteers
- 33 people
- Sponsor
- Kastamonu University
Carpal Tunnel Syndrome (CTS)
Electrophysiological and Functional Recovery After Carpal Tunnel Release
Carpal tunnel syndrome occurs when the median nerve is compressed at the wrist. It can cause pain, numbness, tingling, reduced hand strength, and difficulty performing daily activities.
- Trial name
- ELECTRO-CTS (NCT07803939)
- Testing
- Primary Carpal Tunnel Release Surgery
- Volunteers
- 100 people
- Sponsor
- Istanbul Medipol University Hospital
Ultrasonography, Diagnosis
Added Value of Ultrasonography in the Diagnosis, Management, and Follow-Up of Carpal Tunnel Syndrome
This study aims to assess the ultrasound (US) and nerve conduction studies (NCS) as a tool for diagnosis, treatment planning and follow-up of patients with carpal tunnel syndrome (CTS).
- Conditions
- Ultrasonography, Diagnosis, Management, Follow-Up
- Trial name
- NCT06834061
- Testing
- Ultrasound
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Kafrelsheikh University
Carpal Tunnel Syndrome
Nociceptive Gain Processing After Physical Therapy in Carpal Tunnel Syndrome
This randomized clinical trial will investigate changes in pain intensity and nociceptive gain processing after the application of either physical therapy or surgery in women with carpal tunnel syndrome (CTS).
- Trial name
- NCT02219919
- Testing
- Surgical Group, Physical Therapy Group
- Where
- 2 sites in Spain
- Volunteers
- 100 people
- Sponsor
- Universidad Rey Juan Carlos
Carpal Tunnel Syndrome
Effect of Kinesiotaping and Night Splinting in Patients With Carpal Tunnel Syndome
Carpal tunnel syndrome (CTS) which is defined as a symptomatic compression neuropathy of the median nerve at the level of the wrist.
- Trial name
- NCT04993703
- Testing
- Kinesiotaping, Night Splinting, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Hacettepe University
Overuse Injury, Body Mass Index in Athletes
Hyaluronic Acid in Overuse Knee Pain
Sports activity represents part of day living people, a knee pain originated by high demand joint activity could represent a limitation to continue sports.
- Trial name
- NCT05450458
- Testing
- KNEE JOINT INFILTRATION WITH HYALURONIC ACID WITH SORBITOL SYNOLIS VA
- Where
- Mexico
- Volunteers
- 64 people
- Sponsor
- Hospital Regional Tlalnepantla
Carpal Tunnel Syndrome
Platelet Rich Plasma and Perineural Injection Therapy for Carpal Tunnel Syndrome
Carpal tunnel syndrome (CTS) is the most common peripheral entrapment neuropathy with involving compression of the median nerve in the carpal tunnel.
- Trial name
- NCT02696161
- Testing
- platelet rich plasma, 5% dextrose
- Where
- Taiwan
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Tri-Service General Hospital (TSGH)
Carpal Tunnel Syndrome (CTS), Median Nerve Entrapment
"Ultrasound Measures and Clinical Outcomes in Healthy Individuals, Mild and Moderate Carpal Tunnel Syndrome Patients"
"This study aims to investigate ultrasonographic parameters of the median nerve in healthy individuals and patients with mild and moderate carpal tunnel syndrome (CTS).
- Conditions
- Carpal Tunnel Syndrome (CTS), Median Nerve Entrapment, Electrophysiologic Study, Ultrasound
- Trial name
- NCT07408596
- Testing
- ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Carpal Tunnel Syndrome
The Effect of Perineural Injection Therapy in Patients With Carpal Tunnel Syndrome
Carpal tunnel syndrome (CTS) is the most common peripheral entrapment neuropathy with involving compression of the median nerve in the carpal tunnel.
- Trial name
- NCT02809261
- Testing
- Ultrasound-guided perineural injection with 5% dextrose, Ultrasound-guided perineural injection with normal saline, Normal Saline
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Carpal Tunnel Syndrome
Cross-Cultural Adaptation and Psychometric Validation of the Turkish Version of Atroshi-Lyrén 6-item Symptoms Scale
This study aims to develop Turkish version of the Atroshi-Lyrén 6-item symptoms scale (A-L scale) and to perform validity and reliability evaluations.
- Trial name
- NCT05970692
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ilke KARA
Carpal Tunnel Syndrome, Hand Injuries and Disorders
The ACTS Trial: N-acetylcysteine (NAC) and Night-splinting as a Non-operative Treatment for Carpal Tunnel Syndrome
Carpal tunnel syndrome (CTS) is the most common nerve compression syndrome worldwide, causing significant chronic pain, functional impairment, and lowered quality of life for individuals of various backgrounds.
- Conditions
- Carpal Tunnel Syndrome, Hand Injuries and Disorders, Nerve Compression, Splints
- Trial name
- ACTS (NCT04460521)
- Testing
- N-Acetyl cysteine, Wrist Splint
- Where
- Canada
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Emily Krauss
Carpal Tunnel Syndrome
Carpal Tunnel Syndrome Release Using PSU Retractor
The investigators study aims to evaluate both efficacy and safety of carpal tunnel release using limited incision with the PSU retractor compared to standard incision.
- Trial name
- NCT01017471
- Testing
- Limited incision using PSU retractor
- Where
- Thailand
- Volunteers
- 60 people
- Sponsor
- Prince of Songkla University
Carpal Tunnel Syndrome (CTS), Kinesio Taping
Effectiveness of Kinesiotaping and Peloidotherapy in Carpal Tunnel Syndrome
Patients diagnosed with mild and moderate idiopathic CTS will be randomly divided into three groups. Patients who received 15 sessions of peloid therapy along with a home exercise program will constitute the first group.
- Conditions
- Carpal Tunnel Syndrome (CTS), Kinesio Taping, Exercise, Pain Management
- Trial name
- NCT06977321
- Testing
- Kinesiotaping, Peloidotherapy, Home exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Konya Beyhekim Training and Research Hospital
Carpal Tunnel Syndrome
Correlation of Different Ultrasonographic Indices With Clinical Parameters in Carpal Tunnel Syndrome
The aim of this study is to investigate the relationship between different ultrasonographic indices used in patients with carpal tunnel syndrome and clinical parameters.
- Trial name
- NCT06115187
- Testing
- Nerve ultrasound, Nerve conduction studies
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Carpal Tunnel Syndrome, Compression Neuropathy
Acetyl-l-carnitine to Enhance Nerve Regeneration in Carpal Tunnel Syndrome
Study Hypothesis: Acetyl-l-carnitine increases nerve regeneration in patients with severe carpal tunnel syndrome. Carpal tunnel syndrome (CTS) is common, affecting almost 3% of the general population.
- Trial name
- NCT02141035
- Testing
- Acetyl-l-carnitine
- Where
- 3 sites in Canada
- Volunteers
- 20 people
- Sponsor
- University of Alberta
Carpal Tunnel Syndrome, CTS
Trial of Ultrasound Guided Carpal Tunnel Release Versus Traditional Open Release (TUTOR)
Study to compare the safety and effectiveness of carpal tunnel release with ultrasound guidance (CTR-US) vs. mini-open carpal tunnel release (mOCTR) in patients with symptomatic carpal tunnel syndrome (CTS).
- Conditions
- Carpal Tunnel Syndrome, CTS, Carpal Tunnel
- Trial name
- TUTOR (NCT05405218)
- Testing
- CTR with Ultrasound Guidance using the UltraGuideCTR device, mOCTR
- Where
- 12 sites in United States
- Volunteers
- 122 people
- Sponsor
- Sonex Health, Inc.
Carpal Tunnel Syndrome
COMET-AOA: Median Nerve Stiffness in Mild-Moderate CTS With OMT & Conservative Therapy
To evaluate and quantify changes in the elasticity and shear wave modulus (stiffness) of the median nerve in patients diagnosed with mild to moderate carpal tunnel syndrome following osteopathic manipulative therapy.
- Trial name
- COMET-AOA (NCT06150443)
- Testing
- Osteopathic manipulative treatment (OMT), Conservative treatment
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Kettering Health Network
Carpal Tunnel Syndrome
Pain Reduction Caused by the Combined Treatment of Physiotherapy, Oral Gabapentin and Oral Ibuprofen Arginine.
In the present investigation the pain reduction effects of a physiotherapy technique combined with gabapentin and ibuprofen arginine will be compared to those produced by an ibuprofen arginine (only) treatment, in subjects who…
- Trial name
- NCT06781489
- Testing
- Median nerve neural mobilization, Gabapentin 300mg, Ibuprofen Arginine
- Where
- Venezuela
- Volunteers
- 129 people
- Sponsor
- Universidad Europea de Madrid
Cubital Tunnel Syndrome, Peroneal Nerve Entrapment
Mechanomyography for Predictor of Prognosis in CuTS and PND Patients
The study will be a non-blinded two cohort design consisting only of symptomatic patients with CuTS or compressive peroneal neuropathy or in need of peroneal nerve decompression. The first cohort will be - patients with CuTS.
- Trial name
- NCT04322448
- Testing
- Mechanomyography (MMG)
- Where
- 2 sites in United States
- Volunteers
- 23 people
- Sponsor
- Washington University School of Medicine
Carpal Tunnel Syndrome (CTS)
Low-Level Laser Therapy for Carpal Tunnel Syndrome
Carpal tunnel syndrome (CTS) is the most common peripheral entrapment neuropathy, caused by compression of the median nerve within the carpal tunnel at the wrist.
- Trial name
- NCT07788248
- Testing
- Low-Level Laser Therapy (LLLT), Paraffin Bath Therapy, Standard Conservative Care
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital