Clinical trials: Overweight
Obesity, Pediatric
Redesigning Pediatric Primary Care Obesity Treatment: Virtual House Calls
This study examines a redesign of pediatric primary care overweight/obesity treatment, augmenting typical in-person visits with: (1) direct-to-patient video telehealth to tailor counseling advice to families, (2) that leverages…
- Trial name
- NCT06078774
- Testing
- Virtual Health Coach
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Virginia Commonwealth University
Periodontitis, Obesity
Investigation of Asprosin a Novel Adipokine in Periodontitis
Asprosin, a recently discovered glucogenic adipokine, is mainly synthesized by white adipose tissue and released during fasting. Appetite, glucose metabolism, insulin resistance, cell apoptosis, etc.
- Conditions
- Periodontitis, Obesity, Diabetes Mellitus
- Trial name
- NCT05449821
- Testing
- Serum and salivary samples will be collected. Asprosin levels will be determined by biochemical analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people
- Sponsor
- Ataturk University
Obesity, Bariatric Surgery
Safety Profile of IntRAvenous Lidocaine Use in Coelioscopic Bariatric Surgery
Intravenous lidocaine is efficient for management of post operative pain in abdominal surgery. As previously published in literature the investigators use it during bariatric surgery.
- Trial name
- SPIRAL (NCT02525016)
- Testing
- Blood sampling, Lidocaine
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Hospices Civils de Lyon
Obesity
A Research Study to See How Semaglutide Helps People With Excess Weight, Lose Weight (STEP UP)
This study will look at how much weight participants will lose from the start to the end of the study. The weight loss in participants taking the investigational high dose of semaglutide will be compared to the weight loss in…
- Trial name
- STEP UP (NCT05646706)
- Testing
- Semaglutide
- Where
- 107 sites in United States, Bulgaria and 10 more
- Volunteers
- 1,407 people
- Sponsor
- Novo Nordisk A/S
Hypertension
Sacubitril/Allisartan for Hypertensive Patients With Overweight or Obesity
To compare the efficacy and safety of sacubitril/Allisartan versus amlodipine in the antihypertensive treatment of overweight/obese patients with primary hypertension
- Trial name
- SHOT (NCT07241338)
- Testing
- sacubitril/allisartan, Amlodipine
- Where
- China
- Volunteers
- 104 people
- Sponsor
- Jing Liu
Obesity Hypoventilation Syndrome
Respiratory Muscle Strength in Patients With Obesity Hypoventilation Syndrome (OHS) or With a Precursor of the Disease
Using an extensive set of both volitional and non-volitional tests of respiratory muscle function and strength it is the aim of this study to identify potential determinants for the development of obesity hypoventilation to…
- Trial name
- NCT03854058
- Testing
- magnetic phrenic nerve stimulation
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Wissenschaftliches Institut Bethanien e.V
Type 2 Diabetes
Targeting INflammation Using SALsalate in Type 2 Diabetes (TINSAL-T2D)
Growing evidence over recent years supports a potential role for low grade chronic inflammation in the pathogenesis of insulin resistance and type 2 diabetes.
- Trial name
- TINSAL-T2D (NCT00392678)
- Testing
- Salsalate
- Where
- 16 sites in United States
- Volunteers
- 277 people
- Sponsor
- Joslin Diabetes Center
Obesity, Colon Cancer
A Survey on Attitudes on Financial Incentives
The study concerns a survey of attitudes of the public on issues around personal responsibility for health and the use of financial incentives to promote health in the U.S. and Germany.
- Trial name
- NCT01457976
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Sarcopenic Obesity, Acupuncture Treatment
The Effect of Acupuncture on Sarcopenia and Obesity in Patients With Sarcopenic Obesity.
Sarcopenia is defined by the European Working Group on Sarcopenia in Older People (EWGSOP) as "a syndrome characterized by progressive and generalized loss of skeletal muscle mass and strength, carrying a risk of adverse outcomes…
- Conditions
- Sarcopenic Obesity, Acupuncture Treatment, Exercise
- Trial name
- Sarcopenia (NCT07797140)
- Testing
- Diet and exercise, Acupuncture
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people
- Sponsor
- Ayşe Ukbe Baykut
Diet Modification, Overweight
High-fiber Diet on the Body and the Brain
The central research question aims to understand what drives individuals to make and maintain a vegan / vegetarian dietary decision, to investigate whether there are possible predictors that might influence such a decision and…
- Trial name
- NCT03829189
- Testing
- inulin, maltodextrin
- Where
- Germany
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Max Planck Institute for Human Cognitive and Brain Sciences
Obesity; Drug
Effect and Safety of Benaglutide or Metformin in Patients With Simple Obesity Who Have Inadequate Weight Control
This is a randomized, open, controlled and single-site clinical trail to investigate the effect and safety of Benaglutide or Metformin in patients with simple obesity who have inadequate weight control.
- Trial name
- NCT03593668
- Testing
- Metformin, Benaglutide
- Where
- China
- Volunteers
- 60 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Obesity
Approaches for Improving Long-term Weight Loss
The purpose of this study is to examine two approaches for improving long-term weight loss success. All participants will receive a 12-week, in-person standard behavioral weight loss program followed by either 12 weeks of yoga…
- Trial name
- NCT03799289
- Testing
- Behavioral weight loss followed by yoga instruction, Behavioral weight loss followed by cooking/dietary education instruction
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The Miriam Hospital
Obesity, Overweight
Mazdutide Plus LNG-IUS for Fertility-Sparing Treatment of AEH or Early Endometrial Cancer
This is a prospective, multicenter, randomized, double-blind, placebo-controlled, parallel-group clinical trial designed to evaluate the efficacy and safety of mazdutide combined with a levonorgestrel-releasing intrauterine…
- Conditions
- Obesity, Overweight, Atypical Endometrial Hyperplasia, Endometrial Carcinoma Stage I
- Trial name
- MELIA (NCT07781150)
- Testing
- Mazdutide(Dual GLP-1R/GCGR Agonist), Levonorgestrel-releasing intrauterine system
- Where
- 6 sites in China
- Volunteers
- 128 people
- Sponsor
- Tongji Hospital
Overweight
Do Weight Status and the Level of Dietary Restraint Moderate the Relationship Between Package Unit Size and Food Intake?
The objective of this study is to determine the independent and combined effects of weight status and the level of dietary restraint on the relationship between package unit size and food intake.
- Trial name
- NCT01384552
- Testing
- Package Unit Size - Single Serving, Package Unit Size - Standard
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- The University of Tennessee, Knoxville
Obesity
Virtual Sprouts: Web-based Gardening Games to Teach Nutrition and Combat Obesity
The purpose of this study is to develop, disseminate, and evaluate a web-based nutrition and gardening game using interactive, multiplatform and mobile gaming, rich narrative, a pedagogical agent, meaningful play, and…
- Trial name
- NCT02017158
- Testing
- Virtual Sprouts
- Where
- 2 sites in United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Obesity, Impaired Health
Effectiveness of a Smartphone App for Adolescent Obesity Management
Though face-to-face treatment of childhood obesity can be effective, it is time consuming and costly. This study will test whether treatment can be delivered via an Android app and whether such treatment reduces obesity.
- Conditions
- Obesity, Impaired Health, Psychosocial Problem, Physical Activity
- Trial name
- NCT01804855
- Testing
- W82GO, smartphone application
- Where
- 2 sites in Ireland
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Children's University Hospital, Ireland
Psoriasis, Atherosclerotic Cardiovascular Disease
Pilot Study to Evaluate the Effect of Nicotinamide Riboside on Immune Activation in Psoriasis
Background: Psoriasis causes chronic inflammation in the body. Researchers want to see if a kind of vitamin B3 dietary supplement can help. This might lead to more treatment options.
- Conditions
- Psoriasis, Atherosclerotic Cardiovascular Disease, Obesity, Dyslipidemia
- Trial name
- NCT04271735
- Testing
- Niagen
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Obesity, Weight Reduction
Low-Dose Semaglutide for Weight Loss in Obese Non-Diabetic Pakistani Adults
This prospective, open-label, single-arm, single-center interventional pilot trial aims to evaluate the efficacy and safety of low-dose semaglutide for weight loss and cardiometabolic improvement in obese Pakistani adults without…
- Conditions
- Obesity, Weight Reduction, Cardiometabolic Risk Factors
- Trial name
- NCT07513168
- Testing
- Locally available low-dose semaglutide (0.25 mg, 0.5 mg, 1 mg)
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Asian Institute Of Medical Sciences
Obesity, Overweight
A Study of LY3549492 in Adults With Obesity or Overweight With Type 2 Diabetes
The main purpose of this study, performed under the master protocol W8M-MC-CWMM (NCT06143956), is to evaluate the effects of treatment with LY3549492 compared to placebo in adult participants with obesity or who are overweight…
- Conditions
- Obesity, Overweight, Type 2 Diabetes
- Trial name
- NCT07030868
- Testing
- LY3549492
- Where
- 42 sites in United States, Argentina
- Volunteers
- 1 people
- Sponsor
- Eli Lilly and Company
Overweight and Obesity
Effects of Exercise Intensity on Energy Intake, Appetite and Enjoyment in Overweight and Obese Females
Interval exercise involves short bouts of high intensity exercise interspersed with periods of lower intensity exercise. The benefit is that a shorter total duration of exercise may be required to achieve cardiovascular benefits…
- Trial name
- NCT04437550
- Testing
- Exercise
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Ohio University