Clinical trials: Overweight (BMI > 25), active
Obesity &Amp;Amp;Amp; Overweight, Environmental Exposure
Weight Loss and Endocrine Disrupting Chemicals (EDCs): Lifestyle Interventions to Lose Weight and Reduce EDC Exposure in Individuals With Overweight/Obesity
The goal of this study is to examine the relationship in individuals with overweight/obesity and endocrine disrupting chemical (EDC) exposure through a two-armed, randomized clinical trial.
- Conditions
- Obesity &Amp;Amp;Amp; Overweight, Environmental Exposure, Overweight (BMI > 25)
- Trial name
- LiveWell (NCT07560579)
- Testing
- Educational curriculum, Weight loss Application, Urinary EDC metabolite testing
- Where
- United States
- Volunteers
- 226 people
- Sponsor
- Million Marker Wellness, Inc.
Overweight (BMI > 25), Obesity & Overweight
WB-EMS Combined With Nutritional Guidance for a High-Protein Diet on Body Composition, Muscle Function, Psychological and Functional Outcomes in Older Adults With Excess Adiposity
This is a 16-week randomized controlled trial (RCT) with outcome assessor blinding. The objective is to investigate the effects of resistance training (RT) combined with whole-body neuromuscular electrical stimulation (WB-NMES)…
- Conditions
- Overweight (BMI > 25), Obesity & Overweight, Aging
- Trial name
- WB-EMS (NCT07859072)
- Testing
- Whole-Body Neuromuscular Electrical Stimulation (WB-NMES), Conventional Resistance Training, High-Protein Nutritional Guidance
- Where
- Brazil
- Volunteers
- 36 people
- Sponsor
- Universidade Cesumar (UNICESUMAR)
Overweight (Without Type 2 Diabetes) With Weight-related Comorbidities, Overweight (BMI > 25)
AIM-WEIGHT: AI-Guided Microbiome-Targeted Nutritional Intervention for Weight Loss
AIM-WEIGHT is a clinical study evaluating whether a fixed microbiome-targeted nutritional supplement can support weight loss in adults with overweight or obesity who do not have prediabetes or diabetes.
- Trial name
- AIM-WEIGHT (NCT07736547)
- Testing
- AI-Guided Microbiome-Targeted Nutritional Supplement, Lifestyle counselling
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Varol TUNALI
Impaired Glucose Regulation, Impaired Glucose Tolerance (Prediabetes)
Probiotic Impact on Cognitive Performance, and Metabolic Outcomes in Overweight Young Adults With Impaired Glucose Regulation
This 12-week, double-blind, placebo-controlled trial will examine whether daily supplementation with the Lab4P probiotic can improve cognitive performance and metabolic health in overweight adults aged 18 to 40 with impaired…
- Conditions
- Impaired Glucose Regulation, Impaired Glucose Tolerance (Prediabetes), Prediabetes (Insulin Resistance, Impaired Glucose Tolerance), Overweight (BMI > 25)
- Trial name
- ProCog (NCT07073781)
- Testing
- Lab4p Probiotic Consortium
- Where
- United Kingdom
- Volunteers
- 70 people
- Sponsor
- Leeds Beckett University
Overweight (BMI > 25), Obesity (BMI>30)
Assess the Effects of Replacing Foods High in Refined Carbohydrates With Avocado on Biomarkers of Inflammation.
The objective of this trial is to assess the effects of replacing foods high in refined carbohydrates, particularly added sugars, with avocado (isocaloric substitution) on biomarkers of inflammation and insulin sensitivity in…
- Conditions
- Overweight (BMI > 25), Obesity (BMI>30), Hs-CRP
- Trial name
- NCT07566325
- Testing
- Avocado, Control
- Where
- 2 sites in United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Midwest Center for Metabolic and Cardiovascular Research
Inactivity, Physical, Overweight (BMI > 25)
Effect of Low Volume Sprint Interval Training on Cardiorespiratory Fitness
Low levels of physical activity (PA) are related to poor health and greater risk of premature death in adults. Lack of time is cited as a primary barrier to partaking in PA.
- Conditions
- Inactivity, Physical, Overweight (BMI > 25), Healthy Participants
- Trial name
- NCT07328568
- Testing
- High intensity interval training
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- California State University, San Marcos
Overweight (BMI > 25), Obese, Otherwise Healthy Volunteers
L. Acidophilus (Strain TW01) on Gut Health, Body Composition, and Inflammation
This is a pilot research study to investigate the effects of a probiotic supplement (L. acidophilus, strain TW01) on substances found in the stool and bloodstream, gut bacteria composition, body composition, as well as any…
- Trial name
- NCT06912100
- Testing
- Probiotic
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Healthy, Overweight (BMI > 25)
Effect of Probiotics on Appetite Regulation in Adults With Overweight/Obesity
The goal of this 16-week randomised, placebo-controlled parallel study is to investigate the effect of a newly formed probiotic supplement on satiety and gut microbiota composition in healthy men and women with overweight or…
- Conditions
- Healthy, Overweight (BMI > 25), Overweight , Obesity, Male
- Trial name
- ProBiSat (NCT07715955)
- Testing
- Probiotic supplementation
- Where
- Netherlands
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease, Obesity
Effect of Ketone Esters on Liver Fat Content and Metabolic Function
The goal of this clinical trial is to determine whether ingestion of a ketone ester drink helps improve liver health and blood glucose control.
- Conditions
- MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease, Obesity, Overweight (BMI > 25)
- Trial name
- JV (NCT07097506)
- Testing
- bis-octanoyl (R)-1,3-butanediol (C8 ketone di-ester)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
PCOS (Polycystic Ovary Syndrome), Insulinemic Response
Assessment of Metabolic Changes in Response to Glcuose Intake in Women With Polyendocrine Metabolic Ovarian Syndrome (PMOS)
Polyendocrine metabolic ovarian syndrome (PMOS), previously known as polycystic ovary syndrome (PCOS), is a common endocrine and metabolic condition affecting women of reproductive age.
- Conditions
- PCOS (Polycystic Ovary Syndrome), Insulinemic Response, Overweight (BMI > 25)
- Trial name
- METFLEX (NCT07687264)
- Testing
- Oral Clucose Tolerance Test (oGTT)
- Where
- Switzerland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Depression - Major Depressive Disorder, Overweight (BMI > 25)
Fasting, Exercise, and Diet to Activate Autophagy in Depression
Depression is a common mental health condition that affects millions of people worldwide and is a leading cause of disability. Although current treatments can be effective, many patients do not fully recover or experience…
- Trial name
- AutoFast (NCT07664540)
- Testing
- Performance test
- Where
- Switzerland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Cardiometabolic Conditions, Hypertension (HTN)
To Test the Effectiveness and Implementation Approach of a 3-month PILI Pasifika Program Lifestyle Program With Components of Social Determinants of Health Activities in Real-world Settings (Clinical and Non-clinical Settings) Across 3 Years
In this study, the investigators are conducting a Type 3 hybrid effectiveness-implementation trial to evaluate the implementation of the Community Health Workers (CHW)-delivered PILI Pasifika Program (PPP) across 3 regions, the…
- Conditions
- Cardiometabolic Conditions, Hypertension (HTN), Dyslipidemia, Pre-diabetes
- Trial name
- NCT07387393
- Testing
- PILI (Partnership for Improving Lifestyle Intervention) Pasifika Program
- Where
- 2 sites in United States
- Volunteers
- 400 people
- Sponsor
- University of Hawaii
Disbiosis, Obesity
Limosilactobacillus Fermentum CRL 1446 - CONICET CASASCO
This research study aims to determine if a probiotic called Limosilactobacillus fermentum CRL 1446 can improve the health of people at risk for cardiovascular disease.
- Conditions
- Disbiosis, Obesity, Overweight (BMI > 25), Hypertension (Without Type 2 Diabetes Mellitus)
- Trial name
- NCT07530575
- Testing
- Limosilactobacillus fermentum 1446 CRL CONICET 2.20E+9 CFU
- Where
- 2 sites in Argentina
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- PINER Pastor Manfredi Winery
Food Preferences, Satiety and Food Intake
Sustainable and Inclusive Use of Alternative Proteins in Mediterranean Supply Chains (CIPROMED)
This study investigates the effects of foods enriched with alternative protein sources, including edible insects, microalgae, hemp, and legumes, on appetite regulation, satiety, food preferences, and metabolic health in healthy…
- Conditions
- Food Preferences, Satiety and Food Intake, Appetite Regulation, Overweight (BMI > 25)
- Trial name
- CIPROMED (NCT07553936)
- Testing
- Mediterranean Diet with Control Products (chronic phase), Mediterranean Diet with Insect Protein Bread (chronic phase), Mediterranean Diet with Seaweed-Based Burger (chronic phase)
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Bologna
MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease, Fatty Liver Disease, Nonalcoholic
Investigation of the Efficacy of a Probiotic Mixture in Moderate Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD): A Mechanistic Trial
The goal of this clinical trial is to evaluate whether a specific probiotic mixture can improve liver health in adults with moderate metabolic dysfunction-associated steatotic liver disease (MASLD).
- Conditions
- MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease, Fatty Liver Disease, Nonalcoholic, Overweight (BMI > 25)
- Trial name
- NCT07193927
- Testing
- Lactiplantibacillus plantarum Probiotic Mixture
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- AB Biotics, SA
Overweight (BMI > 25)
SSRD and Overweight
The investigators have previously found that a starch- and sucrosereduced diet (SSRD) has led decreased gastrointestinal symptoms in patients with irritabel bowel syndrome (IBS).
- Trial name
- SSRD (NCT07372235)
- Testing
- Dietary intervention with SSRD in combination with feedback information about the metabolic profile, Dietary intervention with SSRD without any feedback on metabolic profile
- Volunteers
- 300 people
- Sponsor
- Region Skane
Obesity & Overweight, Overweight (BMI > 25)
Intervention Based on the Dietary Guidelines for the Brazilian Population for the Treatment of Overweight and Obesity
This clinical trial aims to evaluate how group-based food and nutrition education interventions, grounded in the recommendations of the Dietary Guidelines for the Brazilian Population, can improve participants' dietary quality…
- Trial name
- NCT07538362
- Testing
- Collective Intervention Based on the Dietary Guidelines for the Brazilian Population, Control Group: Individualized Care
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Federal University of Health Science of Porto Alegre
Overweight (BMI > 25), Males and Females
IMPACT: Immune and Musculoskeletal Physiological Adaptations to Combined Exercise Training & Nutrition
The purpose of this study is to determine whether 12 weeks of exercise training combined with dairy consumption influences inflammation and immune responses in adults with overweight, compared to exercise training alone.
- Trial name
- NCT07513987
- Testing
- Milk, Greek Yogurt, Exercise training
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- York University
Overweight (BMI > 25)
Anti-Inflammatory Effects of Pecan Nut Oil Supplementation in Adults With Overweight: A Randomized Controlled Parallel-Group Clinical Trial
The goal of this clinical trial is to evaluate whether daily supplementation with cold-pressed pecan nut oil can reduce inflammation in adults with overweight.
- Trial name
- NCT07497555
- Testing
- Pecan nut oil supplementation
- Where
- Mexico
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Nuevo Leon
Metabolic Dysfunction Associated Steatotic Liver Disease, Overweight (BMI > 25)
Feasibility of the Paso Program for Patients With Metabolic Dysfunction Associated Steatotic Liver Disease
The purpose of this study is to learn whether the Paso weight loss program is feasible for Mexican and Central American patients with fatty liver disease.
- Conditions
- Metabolic Dysfunction Associated Steatotic Liver Disease, Overweight (BMI > 25), Metabolic Syndrome
- Trial name
- NCT06854185
- Testing
- Paso Program
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Baylor College of Medicine