Clinical trials: Overweight , Obesity
Morbid Obesity
Sonographic Evaluation of Visceral Fat After Bariatric Surgery
Excess visceral fat is a key factor in the development of metabolic syndrome associated with obesity. After bariatric surgery, patients experience weight loss accompanied by a decrease in the amount of total body fat.
- Trial name
- NCT01285791
- Where
- Israel
- Volunteers
- 39 people
- Sponsor
- Hadassah Medical Organization
Obesity, Ventral Hernia
Does a Virtual Coach Offer a Better Solution for Weight Reduction in Ventral Hernia Patients With Obesity?
The purpose for this research is to create a MyChart-enabled virtual coach that assists obese patients lose weight prior to ventral hernia surgery.
- Trial name
- NCT05797974
- Testing
- MyChart enabled virtual weight loss coach, Standard preoperative weight loss tools
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Florida
Obesity
Building Habits Together Online Weight Loss Program
The purpose of this pilot trial is to evaluate the feasibility of a lifestyle intervention where participants will all receive online weight loss counseling delivered via a private Facebook group, but be randomized to the Habit…
- Trial name
- NCT06154213
- Testing
- Building Habits Together, Getting Healthy Together
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of Connecticut
Type 2 Diabetes, Obesity
EMI-EHP Weight Management and Type 2 Diabetes Pragmatic Trial
This is a pragmatic, 24 month, single-center, randomized, open-label, parallel-group trial comparing an obesity-centric approach with a medically-supervised and comprehensive weight loss program (Cleveland Clinic's Endocrinology…
- Trial name
- EMPOWER-T2D (NCT04531176)
- Testing
- Weight Management Program (WMP), Traditional care, Phentermine / Topiramate Extended Release Oral Capsule
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- The Cleveland Clinic
Obesity
Effects of Co-administration of Canagliflozin 300 mg and Phentermine 15 mg With Placebo in the Treatment of Non-Diabetic Overweight and Obese Participants
The purpose of this study is to compare the effects of canagliflozin and phentermine to those of placebo to promote on a change in body weight over a 26 week period.
- Trial name
- NCT02243202
- Testing
- Canagliflozin, Phentermine
- Where
- 17 sites in United States
- Volunteers
- 335 people
- Sponsor
- Janssen Research & Development, LLC
Endometrial Cancer, Obesity
FitEx for Endometrial Cancer Survivors: Initial Efficacy
The goal of this clinical trial is to compare physical activity outcomes between endometrial cancer survivors randomized to 1 of 3 conditions: 1) usual care, 2) FitEx, 3) FitEx+yoga.
- Conditions
- Endometrial Cancer, Obesity, Sedentary Behavior, Quality of Life
- Trial name
- NCT05737745
- Testing
- Self-monitoring, Group-dynamics, Weekly virtual sessions- Standard
- Where
- United States
- Volunteers
- 111 people
- Sponsor
- Carilion Clinic
Obesity
Prevention of Obesity in Women Via Estradiol Regulation
The purpose of this study is to evaluate potential mechanisms by which estradiol deficiency accelerates fat gain and abdominal fat accumulation in women.
- Trial name
- POWER (NCT00687739)
- Testing
- leuprolide acetate, Estradiol Transdermal, progressive resistance exercise training
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Loss-of-Control Eating, Obesity/Overweight
Pharmacological and Behavioral Treatments After Bariatric Surgery: Maintenance Treatment (Stage 2a)
This study will test the effectiveness of naltrexone/bupropion medication as a maintenance therapy for the treatment of loss-of-control eating and weight loss following bariatric surgery.
- Trial name
- NCT04605081
- Testing
- Naltrexone and Bupropion (NB) medication
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Yale University
Obesity, Childhood, Neural Development
Effect of Liraglutide on Neural Responses to High Fructose Corn Syrup in Individuals With Obesity.
To study the effects of liraglutide on neural responses to high fructose corn syrup (HFCS) in individuals with obesity.
- Trial name
- NCT03500484
- Testing
- Liraglutide
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Yale University
Obesity
Pentax Airway Scope (AWS) Intubation
This study will compare the Macintosh laryngoscope with the Pentax. The Pentax AWS is a novel airway management device that is designed to facilitate laryngoscopy and endotracheal intubation.
- Trial name
- NCT00667693
- Testing
- Macintosh laryngoscope, Pentax AWS
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- The Cleveland Clinic
Obesity and Physical Inactivity in Adolescents
Social Exergaming for Healthy Weight in Adolescent Girls
The purpose is to evaluate the feasibility of a 12-week exergaming dance program for adolescent girls. This study combines dancing, video games, and a full body work-out to test if video games can increase physical activity and…
- Trial name
- Klub Kinect (NCT02003963)
- Testing
- Klub Kinect
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Binge-Eating Disorder
Acceptance-based Group Intervention for Binge Eating
This study proposes to compare a brief Acceptance and Commitment Therapy (ACT) group intervention to an active control group in a sample of 154 overweight or obese binge eating Veterans who have completed the VA's national…
- Trial name
- NCT01757847
- Testing
- Acceptance and Commitment Therapy (ACT), Brief MOVE-II control group intervention
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- VA Office of Research and Development
Children, Overweight
The Odense Overweight Intervention Study
Strong and consistent evidence have shown that overweight, including obesity, is an important risk factor for the development of cardiovascular disease (CVD) in adults.
- Conditions
- Children, Overweight, Obesity, Metabolic Syndrome
- Trial name
- OOIS (NCT01574352)
- Testing
- Small intervention, Intervention camp
- Where
- 2 sites in Denmark
- Volunteers
- 115 people
- Sponsor
- University of Southern Denmark
Barrett's Esophagus, Obesity
Modulation of Esophageal Inflammation in Barrett's Esophagus by Omega-3 Fatty Acids
This study is being done to understand the effect of dietary omega-3 fats in decreasing tissue inflammation in Barrett's esophagus.
- Trial name
- NCT01733147
- Testing
- Omega-3 polyunsaturated fatty acids
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Mayo Clinic
Obesity
Healthy Eating and Active Living Taught at Home (HEALTH) Dissemination & Implementation (D&I)
This project evaluates the effectiveness of an evidence-based intervention (HEALTH) to prevent weight gain and promote weight loss when disseminated and implemented in real-world settings, through Parents as Teachers.
- Trial name
- HEALTH D&I (NCT03758638)
- Testing
- Healthy Eating & Active Living Taught at Home, Usual Care
- Where
- United States
- Volunteers
- 620 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Obesity, Impaired Glucose Tolerance
The Effect of Exenatide on Weight and Hunger in Obese, Healthy Women
This study will look at the effect of exenatide, a drug which has been approved for the treatment of type 2 diabetes, on body weight, appetite and energy expenditure among moderately obese women without diabetes.
- Trial name
- NCT00456885
- Testing
- exenatide
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Obesity, PreDiabetes
Reducing Cardiometabolic Risk and Promoting Functional Health in Older Adults With Obesity and Prediabetes
Obesity and pre-diabetes threatens the overall health and functional independence of older adults but lifestyle weight management for diabetes prevention, soon to be reimbursed by Medicare, can reduce this burden.
- Conditions
- Obesity, PreDiabetes, Aging
- Trial name
- Sustain-DPP (NCT03500640)
- Testing
- DPP Intensive: 30-minute calls, DPP Support: 15-minute calls
- Where
- United States
- Volunteers
- 314 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Weight Loss, Obesity
Charge: A Text Messaging-based Weight Loss Intervention
This study evaluates different versions of a text messaging-based app for weight loss. This study will place participants to 1 of 32 experimental conditions that reflect different texting components and levels.
- Trial name
- NCT03254940
- Testing
- Charge
- Where
- United States
- Volunteers
- 534 people, healthy volunteers welcome
- Sponsor
- Duke University
Cystic Fibrosis-related Diabetes, Cystic Fibrosis
SGLT2 Inhibitor Therapy in Cystic Fibrosis-related Diabetes
This will be a placebo-controlled, randomized, double blind, crossover study with a 4 week wash out period. Collect pilot data on the safety, tolerability, and feasibility of empagliflozin therapy in overweight/obese patients…
- Trial name
- NCT06149793
- Testing
- Empagliflozin
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Minnesota
Obesity
Increasing Uptake of Behavioral Weight Loss Programs Among Primary Care Patients
This pilot trial will test feasibility and acceptability of a primary care-based intervention that aims to increase the portion of patients who enter evidence-based behavioral weight loss treatment.
- Trial name
- NCT02708121
- Testing
- Motivational Intervention, Comparator Intervention
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- University of Florida