Clinical trials: Overweight and Obese Children
Obesity
Influence of a Lifestyle Intervention in Preschool Children on Physiological and Psychological Parameters
Childhood obesity and low fitness tracks into adulthood and carries significant co-morbidities. The investigators test the hypothesis that a multidisciplinary multilevel lifestyle intervention in preschool children in the French…
- Trial name
- Ballabeina (NCT00674544)
- Testing
- Lifestyle intervention
- Where
- Switzerland
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- University of Lausanne Hospitals
Obesity
Impact of Dietary Fiber as Prebiotics on Intestinal Microbiota in Obese Thai Children
This study evaluates the changes in gut microbiota composition, body fat, children's eating behaviors, plasma amino acids, and satiety hormones (Peptide-YY and GLP-1) after a 6-month period in obese Thai children.
- Trial name
- NCT03968003
- Testing
- Inulin
- Where
- Thailand
- Volunteers
- 165 people
- Sponsor
- Chulalongkorn University
Childhood Obesity
Lifestyle in Pregnancy and Offspring - Comparison Between Children Born to Obese Women and Children Born to Normal Weight Women
Children born to obese women are at risk of increased adiposity and later adverse metabolic outcomes. We have conducted a follow-up study on an existing clinical trial, called the LiP study (Lifestyle in Pregnancy), registration…
- Trial name
- LiPO (NCT01918423)
- Testing
- Lifestyle intervention during pregnancy
- Where
- Denmark
- Volunteers
- 258 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Diabetes
Food Intake and Appetite in the Children of Mothers With Diabetes
This protocol is for study of the effect of inhibition of parasympathetic outflow on insulin secretion and glucose metabolism. Insulin secretion will be measured during infusions of escalating doses of atropine.
- Trial name
- NCT00339313
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Obesity, Insulin Resistance
Vitamin K to Slow Progression of Dyslipidemia and Diabetes Risk (Vita-K 'n' Kids Study II)
Animal studies have found that vitamin K-dependent proteins matrix Gla protein and osteocalcin beneficially influence lipid and glucose metabolism, respectively.
- Conditions
- Obesity, Insulin Resistance, Obesity in Diabetes, Nutritional and Metabolic Diseases
- Trial name
- NCT02959762
- Testing
- Low-Dose Vitamin K2 (menaquinone-7; 45-mcg/d), High-Dose Vitamin K2 (menaquinone-7; 90 mcg/d)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Augusta University
Cardiovascular Diseases, Heart Diseases
Behavior Change Family Counseling to Reduce Rate of Weight Gain in At-Risk Children
This study will train primary care providers to counsel families on behavior change that is aimed at reducing the rate of weight gain in at-risk children.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Obesity
- Trial name
- NCT00241891
- Testing
- Single behavior intervention, Multiple behavior interventions, Control Intervention unrelated to weight
- Where
- United States
- Volunteers
- 158 people
- Sponsor
- Children's Hospital of Philadelphia
Overweight and Obesity
Loss of a Healthy Weight Advantage Among Mexican-American Children
Although research indicates foreign-born Mexican-Americans possess a healthy weight advantage relative to U.S.-born Mexican-Americans, patterns are less clear for children and may be changing over time.
- Trial name
- NCT03261882
- Testing
- Nativity
- Volunteers
- 11,987 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Physical Inactivity, Obesity, Childhood
Gamified Family-based Health Exercise Intervention to Improve Adherence to 24-h Movement Behaviors Recommendations in Children.
Physical inactivity is the fourth most important risk factor for mortality worldwide and it contributes to weight gain and obesity.
- Conditions
- Physical Inactivity, Obesity, Childhood, Sedentary Behavior
- Trial name
- Move On (NCT05741879)
- Testing
- Gamified exercise training, Standard Care
- Where
- Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universidad Pública de Navarra
Obesity, Childhood
Effect of a Three Combined Probiotics Supplementation on Weight Loss in Obese/Overweight Children
This program is a double-blind, randomized, placebo-controlled study. Investigators expect to enroll 100 overweight or obese children those ages 6 to 18 years.
- Trial name
- NCT03883191
- Testing
- L. rhamnosus bv-77, B. animalis subsp. lactis CP-9 and L. salivarius AP-32 mix probiotics powder
- Where
- Taiwan
- Volunteers
- 82 people
- Sponsor
- China Medical University Hospital
Obesity, Insulin Resistance
Correction of Vitamin D Levels and Its Effect on Insulin Resistance and Weight Gain in Obese Youth
Vitamin D deficiency is extremely common in obese youth. In our obese population followed in the Endocrinology clinic at Children's Medical Center Dallas, vitamin D levels were inversely correlated with a measure of insulin…
- Conditions
- Obesity, Insulin Resistance, Vitamin D Deficiency
- Trial name
- NCT02168660
- Testing
- Vitamin D3
- Where
- United States
- Volunteers
- 109 people
- Sponsor
- Perrin C White, MD
Adolescent Health
Health Behavior in School-Age Children: NEXT Longitudinal Study 2009-2016
NEXT is a seven-year longitudinal assessment of a representative sample of U.S. adolescent and young adults starting at grade 10.
- Trial name
- NCT01031160
- Where
- United States
- Volunteers
- 4,902 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Perioperative Respiratory Adverse Events, Airway Management
Airway Management and Weight in Children
The investigators in this study want to see how overweight/obese children who undergo elective surgery requiring airway management react to general anesthesia.
- Trial name
- NCT03996343
- Testing
- Endotracheal intubation, Laryngeal mask airway
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Michigan
Physical Inactivity, Overweight and Obesity
Effects of Parental Involvement in Exergames Play on Physical and Mental Health on Overweight and Obese Male Adolescent
In recent years, with the rising obesity rate, overweight and obesity have become a hot issue of public health. As a sensitive and special group, teenagers shoulder the heavy responsibility of building the motherland, so their…
- Conditions
- Physical Inactivity, Overweight and Obesity, Psychosocial Problem
- Trial name
- NCT05769374
- Testing
- cooperative versus competitive AVG play
- Where
- China
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia
Pediatric Obesity
Healthy Start to Increase Physical Activity and Improve Healthy Eating in Early Childcare Centres
Childhood obesity is one of the greatest challenges facing public health and recent evidence shows it begins in preschool aged children.
- Trial name
- NCT02375490
- Testing
- Healthy Start
- Where
- 2 sites in Canada
- Volunteers
- 897 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Non-alcoholic Fatty Liver Disease, Obesity
Effect of Exercise on Hepatic Fat in Overweight Children
The objective of the present study is to evaluate the effect of 6 months exercise intervention program on hepatic fat fraction in overweight children.
- Conditions
- Non-alcoholic Fatty Liver Disease, Obesity, Metabolic Syndrome
- Trial name
- EFIGRO (NCT02258126)
- Testing
- Multidisciplinary intervention program
- Where
- Spain
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- University of the Basque Country (UPV/EHU)
Overweight and Obesity, Stunted Growth
Intervention in Children With Malnutrition
Malnutrition is an epidemiologic problem with high prevalence in Mexico. Mexican children present a double burden of malnutrition characterized by the coexistence of undernutrition and micronutrient deficiency alongside excess…
- Conditions
- Overweight and Obesity, Stunted Growth, Malnutrition, Child, Nutrient Deficiency
- Trial name
- NCT04915638
- Testing
- Experimental intervention group with enriched cookies
- Where
- Mexico
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Marta Alicia Menjivar Iraheta
Childhood Obesity
Effectiveness of an IMB-based Intervention for Reducing Sweetened Beverages Consumption in Preschool Children
Sugar-sweetened beverages and over consumption of 100% fruit juice add unneeded calories to the diets of children, potentially leading to overweight.
- Trial name
- NCT03957148
- Testing
- Sugar-sweetened beverage reduction education for preschool children
- Where
- United States
- Volunteers
- 484 people, healthy volunteers welcome
- Sponsor
- UConn Health
Childhood Obesity
YMCA-Physical Activity and Nutrition
There is an epidemic rise in the number of overweight and obese children. Overweight and obesity in children tracks into adulthood and carries elevated risk of chronic diseases such as seen with the metabolic syndrome (i.e.…
- Trial name
- YMCA-PAN (NCT01107678)
- Testing
- Healthy Snacks and Organized Physical Activity
- Where
- United States
- Volunteers
- 966 people, healthy volunteers welcome
- Sponsor
- University of Kansas
Children, Overweight
The Odense Overweight Intervention Study
Strong and consistent evidence have shown that overweight, including obesity, is an important risk factor for the development of cardiovascular disease (CVD) in adults.
- Conditions
- Children, Overweight, Obesity, Metabolic Syndrome
- Trial name
- OOIS (NCT01574352)
- Testing
- Small intervention, Intervention camp
- Where
- 2 sites in Denmark
- Volunteers
- 115 people
- Sponsor
- University of Southern Denmark
Obesity, Childhood, Energy Density
Eat Healthy for Families
This study investigates the effect of a low energy-density dietary prescription as compared to MyPlate recommendations in preschool children at risk for obesity.
- Conditions
- Obesity, Childhood, Energy Density, Diet Quality
- Trial name
- NCT03394326
- Testing
- family-based obesity prevention lifestyle intervention
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University of Delaware