Clinical trials: Overweight and Obese Women
Insulin Resistance
The Effects of Cocoa Flavanols on Insulin Resistance in an 'At-risk' Population
The aim of the current study is to investigate the ability of antioxidants found in cocoa ('flavanols') to increase the body's sensitivity to the hormone insulin.
- Trial name
- NCT01201590
- Testing
- High Flavanol Cocoa, Low Flavanol Cocoa
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Polycystic Kidney, Autosomal Dominant
Daily Caloric Restriction and Intermittent Fasting in Overweight and Obese Adults With Autosomal Dominant Polycystic Kidney Disease
The proposed research will determine the feasibility of delivering two behavioral weight loss interventions for 1 year in adults with autosomal dominant polycystic kidney disease (ADPKD) who are overweight or obese.
- Trial name
- NCT03342742
- Testing
- Weight Loss
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- University of Colorado, Denver
Infertility, Weight Loss
Weight Loss on IVF Outcomes in Overweight and Obese Infertile Women
The aim of this study is to determine whether weight loss prior to in vitro fertilization (IVF) improves live birth outcomes in overweight and obese infertile women.
- Conditions
- Infertility, Weight Loss, Obesity, IVF
- Trial name
- NCT07174817
- Testing
- weight loss
- Where
- China
- Volunteers
- 197 people
- Sponsor
- Peking University People's Hospital
Cardiovascular Diseases, Heart Diseases
Trial of Activity for Adolescent Girls (TAAG)
To test the effectiveness of a multicomponent school-based and community-linked intervention in preventing the decline in physical activity levels and cardiovascular fitness in girls in grades 6-8.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Obesity
- Trial name
- TAAG (NCT00006409)
- Testing
- Trial of Activity for Adolescent Girls (TAAG)
- Volunteers
- 8,727 people
- Sponsor
- University of North Carolina, Chapel Hill
Iron Deficiency Anemia of Pregnancy
Adiposity and Iron Requirements in Pregnancy
This study aims to explore how body fat influences the response to either 25 or 50 mg of daily iron supplements during pregnancy.
- Trial name
- ADIPREG (NCT06425796)
- Testing
- Adiposity and Iron Requirements in Pregnancy (ADIPREG)
- Where
- 3 sites in United Kingdom
- Volunteers
- 312 people, healthy volunteers welcome
- Sponsor
- University of Ulster
Hot Flushes, Menopause, Premature
The Role of Vitamin D in Menopause: Relationship to Menopausal Symptoms in Body Composition
Specific Aim 1: To compare effects of Vitamin D supplementation to usual care on symptoms in women transitioning to early postmenopause and determine the associated effect size in order to conduct a power analysis for a future…
- Conditions
- Hot Flushes, Menopause, Premature, Obesity, Vitamin D Deficiency
- Trial name
- FLASH (NCT01141972)
- Testing
- Vitamin D
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Obesity, Weight Loss
Evaluation of Alternative Exercise Treatments on Weight Loss in Overweight Women.
The purpose is to examine the additional effect of either yoga or resistance exercise on weight loss weight combined with a standard behavioral weight loss intervention.
- Trial name
- NCT00177632
- Testing
- behavioral weight loss
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Obesity
Promotion of Exercise and Health in Obesity
The primary objectives of this randomized clinical trial are a) to implement and test the impact of a 1-year lifestyle obesity treatment program based on Self-Determination Theory on 3-year change in physical activity and…
- Trial name
- PESO (NCT00513084)
- Testing
- SDT and Motivational Interviewing in Obesity Treatment
- Where
- Portugal
- Volunteers
- 259 people
- Sponsor
- Technical University of Lisbon
Obesity, Contraception
Effectiveness of Orally Dosed Emergency Contraception in Obese Women - UPA
Obese women are significantly more likely than their normal BMI counterparts to experience failure of orally-dosed emergency contraceptives.
- Trial name
- UPA-Obesity (NCT02859337)
- Testing
- UPA-ECx1, UPA-ECx2
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Obesity
Resistance and Aerobic Exercise With Nutritional Supplementation in Men and Women
The purpose of this study is to identify the influence of resistance and aerobic exercise with different nutritional supplements in middle-aged men and women on various physiological measures.
- Trial name
- S-017 (NCT00812409)
- Testing
- Whey protein supplementation with exercise, Non protein supplementation with exercise (control)
- Where
- United States
- Volunteers
- 580 people, healthy volunteers welcome
- Sponsor
- Purdue University
Gestational Diabetes, Obesity
Growth Hormone Resistance of Beta-cells A
The purpose of the research study is to better understand how beta-cells (cells in the pancreas that make insulin and help regulate blood sugar) respond to growth hormone in people with a personal history of gestational diabetes…
- Conditions
- Gestational Diabetes, Obesity, Healthy
- Trial name
- GHRB-A (NCT06571487)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Overweight or Obesity
NDPP-NextGen: A Clinical Trial to Reduce Intergenerational Obesity and Diabetes Risks
The goal of this clinical trial is to test an enhanced version of the National Diabetes Prevention Program (NDPP-NextGen) that is tailored to young women in childbearing years.
- Trial name
- NCT05674799
- Testing
- NDPP-NextGen
- Where
- United States
- Volunteers
- 403 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Obesity
Calcium Over Postprandial Effects of Fatty Meal on Metabolism, Blood Pressure, Oxidative Stress, Endothelial Function.
The purpose of the study is to investigate calcium acute influence over the postprandial effects of a fatty meal on serum calcium, plasma glucose and triglycerides, blood pressure, oxidative stress, and endothelial function in…
- Trial name
- NCT02137434
- Testing
- Dietary calcium, Supplementary calcium
- Where
- Brazil
- Volunteers
- 15 people
- Sponsor
- Rio de Janeiro State University
Polycystic Ovary Syndrome, Insulin Resistance
Endocrine and Menstrual Disturbances in Women With Polycystic Ovary Syndrome (PCOS)
Polycystic ovary syndrome (PCOS) is a common endocrine disorder in reproductive age women, which causes disordered follicle growth and ovulation resulting in infertility.
- Conditions
- Polycystic Ovary Syndrome, Insulin Resistance, Vitamin D Deficiency, Obesity
- Trial name
- EMDPCOS (NCT03652987)
- Where
- United Kingdom
- Volunteers
- 300 people
- Sponsor
- St George's, University of London
Endometrial Cancer
Telehealth-Based Resistance Training Intervention for Endometrial Cancer Survivors
This 2-arm pilot trial will enroll 40 participants to test the feasibility, adherence, and benefits of a home-based strength training intervention for endometrial cancer survivors relative to a wait-listed control group.
- Trial name
- NCT03722030
- Testing
- Baseline Measures, Strength-Training, Mid-point Measures
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Wisconsin, Madison
Obesity
Partial Meal Replacement and Inulin in Obese Women
The objective of this study was to test the efficacy of a partial meal replacement added with vitamins, minerals and inulin on weight reduction, blood lipids and micronutrients intake in obese Mexican women
- Trial name
- NCT01505023
- Testing
- Partial meal replacement, Partial meal replacement with inulin, Inulin
- Where
- Mexico
- Volunteers
- 179 people
- Sponsor
- Cindetec
Obese, Weight Loss
Effects of Adding L-BAIBA or L-BAIBA + Grains of Paradise to Exercising Adult Overweight and Obese Men and Women
The goal of this intervention study is to examine changes in body composition, weight loss, and cardio-metabolic risk factors after adding supplementation of L-Beta aminoisobutyric acid (L-BAIBA) and Grains of Paradise to…
- Conditions
- Obese, Weight Loss, Body Weight, Cardiometabolic Syndrome
- Trial name
- GOP (NCT05775003)
- Testing
- Exercise
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Lindenwood University
Recurrent Pregnancy Loss, Overweight , Obesity
Effects of High-frequency Left Dorsolateral Prefrontal rTMS on Heart-brain Coupling in Women With Recurrent Pregnancy Loss and Elevated BMI
This randomized, sham-controlled mechanistic trial will examine whether a single session of high-frequency repetitive transcranial magnetic stimulation, rTMS, applied to the left dorsolateral prefrontal cortex can modify…
- Conditions
- Recurrent Pregnancy Loss, Overweight , Obesity, Heart-Brain Coupling
- Trial name
- NEURO-CARD-BMI (NCT07561931)
- Testing
- Real repetitive transcranial magnetic stimulation
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Shenyang Medical College
Overweight, Obesity
Does Dairy Benefit Bone & Body Composition in Overweight Girls Undergoing a Weight Management Program?
The purpose of this study is to examine whether increased dairy intake, at the level recommended by Canada's Food Guide, combined with healthy eating and exercise, will improve body composition and bone turnover over 12 weeks in…
- Conditions
- Overweight, Obesity, Children
- Trial name
- NCT02581813
- Testing
- I.D.E.A.L. for Adolescents Study - Higher Dairy, I.D.E.A.L. for Adolescents Study - Lower Dairy
- Where
- Canada
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Brock University
Diabetes Mellitus, Type 2, Kidney Disease, Chronic
Randomized Study Comparing Metabolic Surgery With Intensive Medical Therapy to Treat Diabetic Kidney Disease
Proven therapy for DKD is primarily limited to RAAS blockers and SLGT2i. Weight reduction has the potential to become an additional and much needed treatment option.
- Conditions
- Diabetes Mellitus, Type 2, Kidney Disease, Chronic, Kidney Injury
- Trial name
- OBESE-DKD (NCT04626323)
- Testing
- Roux-en-Y gastric bypass, Best medical treatment
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Hospital Alemão Oswaldo Cruz