Clinical trials: Overweight and Obese Women
Autosomal Dominant Polycystic Kidney, Obesity
Glucagon-Like Peptide-1 Receptor Agonist in ADPKD
The proposed clinical trial aims to assess if a year of treatment with a glucagon-like peptide 1 receptor agonist, a medication approved for weight management that also improves the body's response to glucose and insulin, can…
- Trial name
- NCT06582875
- Testing
- Tirzepatide
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- University of Colorado, Denver
Obesity, Maternal, Lifestyle
Supporting Lifestyle Changes After Delivery
Use of information and communication technology -based health behavior change support system in modifying lifestyle after delivery among women with obesity.
- Trial name
- STELLA (NCT06241144)
- Testing
- Information and communication technology -based health behavior change support system
- Where
- Finland
- Volunteers
- 200 people
- Sponsor
- Oulu University Hospital
Obesity, Fertility
Effects of Dietary Omega-3 Fatty Acids on Reproductive Hormones in Obese Women
The United States has the highest prevalence of obesity among all countries surveyed in 2012 by the Organization for Economic Cooperation and Development.
- Trial name
- NCT01894581
- Testing
- LOVAZA, GnRH
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Bariatric Surgery, Obesity
Ovarian Reserve and Bariatric Surgery
The expansion of the obesity epidemic is accompanied with an increase in bariatric procedures, in particular in women of reproductive age.
- Conditions
- Bariatric Surgery, Obesity, Reproductive Health, Fertility
- Trial name
- BARIAOVO (NCT04583150)
- Testing
- Bariatric surgery
- Where
- 14 sites in France
- Volunteers
- 238 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Obesity, Substance Abuse
Yappalli - The Road to Choctaw Health
This is an obesity and alcohol, tobacco, and other drug (ATOD) use risk prevention and health leadership program. This project will include 150 at-risk adult Native women across 5 communities (30 women from each community) in the…
- Trial name
- NCT02400554
- Testing
- Yappalli
- Where
- United States
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- University of Washington
Obesity, Insulin Resistance
Assessing the Value of Red Grapes Polyphenol Supplementation on Metabolic Parameters in Obese Insulinoresistant Subjects
Obesity, chronic disease, is a real public health problem because of its high prevalence but also because of the high risk of complications, including insulin resistance (IR) and type 2 diabetes (T2D).
- Conditions
- Obesity, Insulin Resistance, Menopause
- Trial name
- POLYGIR (NCT02633150)
- Testing
- Supplementation with red grapes polyphenol
- Where
- France
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Infant,Premature, Body Weight
Serial Assessment of Body Fat Accrual in Very Preterm Infants
Despite evidence that both rapid weight gain and excessive body fat accrual are associated with overweight and obesity, usual neonatal care of preterm infants does not include assessment of body fat accrual.
- Conditions
- Infant,Premature, Body Weight, Adiposity
- Trial name
- NCT03575897
- Testing
- Assessment of infant body composition
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Alabama at Birmingham
Obesity, Cognitive Ability, General
Physical Activity and Intermittent Exercise Training for Cardiovascular and Cognitive Gain in Obese Women
One hundred participants from a combination of (a) local advertisements and/or (b) those whose details are held on a research database (of previous volunteers indicating willingness to be contacted about future studies) will be…
- Conditions
- Obesity, Cognitive Ability, General, Cardiovascular Disease
- Trial name
- NCT02853279
- Testing
- Interval exercise training, Continuous exercise training (CON)
- Where
- 2 sites in United Kingdom
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Pregnancy Related, Obesity, Maternal
Remotely Monitored Exercise Program in Pregnant Women With Obesity
Pregnant women with obesity will be invited to participate in structured home-based exercise programme, remotely monitored
- Trial name
- GROB (NCT05331586)
- Testing
- Remote Exercise
- Where
- Portugal
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
Diabetes, Gestational
Effect of Strength-resistance Exercise in the Reduction of Gestational Diabetes in Pregnant Women with Overweight or Obesity
The aim of this trial is to test the efficacy of regular resistance exercise in early pregnancy to prevent gestational diabetes mellitus in overweight/ obese pregnant women.
- Trial name
- NCT05840497
- Testing
- Resistance exercise
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Fundacion Miguel Servet
Influenza, Obesity
Effectiveness and Tolerability of Influenza Vaccine in Patients at Risk for Severe and Complicated Influenza
The aim of the study is to evaluate simultaneously the immunological and clinical efficacy and tolerability of an influenza vaccine, inactivated, quadrivalent, with cleaved virus, in patients at risk for severe and complicated…
- Conditions
- Influenza, Obesity, Pregnancy; Infection, Elderly Infection
- Trial name
- NCT06286488
- Testing
- Vaxigrip
- Where
- Poland
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw
Vitamin D Deficiency, Insulin Resistance
Assessment of Influence of Vitamin D on Insulin Secretion and Sensitivity in Obese Teenage Girls
The purpose of the study is to assess the relationship between vitamin D status and insulin- glucose dynamics in obese Adolescents.
- Conditions
- Vitamin D Deficiency, Insulin Resistance, Insulin Sensitivity, Obesity
- Trial name
- NCT00851396
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Alabama at Birmingham
Metabolic Syndrome
Salmon Peptide Fraction: Safety and Cardiometabolic Health
The overall goal of this study is to verify the safety of 15g of salmon peptide fraction (SPF), and to test the effects on metabolic syndrome risk factors of two doses of SPF (7.5g and 15g) in overweight-obese men and women.
- Trial name
- SPF1 (NCT05025462)
- Testing
- Supplement dose 15g/d, Supplement dose 7.5g/d
- Where
- Canada
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Laval University
PCOS
A Treatment Legacy Effect of Metformin in Obese Women With PCOS
Metformin has multiple health promoting effects and it may serve as a preventive measure for individuals who are at high risk for metabolic complications.
- Trial name
- NCT04566718
- Testing
- Metformin
- Where
- Slovenia
- Volunteers
- 40 people
- Sponsor
- University Medical Centre Ljubljana
Overweight, Obesity
3mg Liraglutide for Overweight or Obesity
In this study investigators will investigate the beneficial metabolic sequelae of Liraglutide in patients with obesity or overweight; including changes in vital signs, anthropometric characteristics (weight, body mass index and…
- Conditions
- Overweight, Obesity, Infertility, Female
- Trial name
- NCT03885297
- Testing
- Saxenda, Lifestyle modification, Metabolomics
- Where
- United Kingdom
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University Hospitals Coventry and Warwickshire NHS Trust
Prader-Willi Syndrome
Optimizing the Social Engagement System in Prader-Willi Syndrome: Insights From the Polyvagal Theory
The Polyvagal Theory focuses on how function and structure changed in the vertebrate autonomic nervous system during evolution. The theory is named for the vagus, a major cranial nerve that regulates bodily state.
- Trial name
- NCT03101826
- Testing
- Listening Project Protocol
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Indiana University
Obesity
The Effect of 5-Hydroxytryptophan (5-HTP) on Satiety
The aim of the study is to show evidence of the efficacy of 5-HTP to induce satiety and to reduce food intake (confirmatory study).
- Trial name
- NCT00328913
- Testing
- 5-hydroxytryptophan (food supplement)
- Where
- Netherlands
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- TNO
Metabolic Syndrome, Obesity
An Exercise RCT Targeting African-American Women With Metabolic Syndrome and High Risk for Breast Cancer
Among African-American women, in whom metabolic syndrome (MetS) is very prevalent and breast cancer mortality rates are high, it is hypothesized that intervening on MetS to improve the MetS profile may prove to be a means to…
- Trial name
- NCT02103140
- Testing
- Facility-based Exercise, Home-based Exercise
- Where
- United States
- Volunteers
- 213 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Low Physical Activity Level, Central Obesity
Physical Activity on Prescription in Overweight Older Adults
This randomized controlled study evaluates the effect of individualized physical activity on prescription (PAP) in older overweight adults.
- Conditions
- Low Physical Activity Level, Central Obesity, Metabolic Syndrome
- Trial name
- NCT02320760
- Testing
- Physical activity on prescription
- Volunteers
- 102 people
- Sponsor
- Karolinska Institutet
Hot Flushes, Menopause, Premature
The Role of Vitamin D in Menopause: Relationship to Menopausal Symptoms in Body Composition
Specific Aim 1: To compare effects of Vitamin D supplementation to usual care on symptoms in women transitioning to early postmenopause and determine the associated effect size in order to conduct a power analysis for a future…
- Conditions
- Hot Flushes, Menopause, Premature, Obesity, Vitamin D Deficiency
- Trial name
- FLASH (NCT01141972)
- Testing
- Vitamin D
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
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