Clinical trials: Overweight and Obese Women
Overweight, Obesity
Iron Absorption and Transfer to the Fetus During Pregnancy in Normal Weight and Overweight/Obese Women and the Effects on Infants Iron Status
Overweight and obesity causes low-grade systemic inflammation, which sharply increases risk for iron deficiency. Studies in our laboratory have shown that this is mainly the result of reduced dietary iron absorption because of…
- Conditions
- Overweight, Obesity, Pregnancy
- Trial name
- PIANO (NCT02747316)
- Testing
- Stable iron isotope 57 (57Fe) labeled iron solution, Stable iron isotope 58 (58Fe) labeled iron solution
- Where
- Switzerland
- Volunteers
- 83 people
- Sponsor
- Swiss Federal Institute of Technology
Non-Alcoholic Fatty Liver Disease
Effects of TOTUM-448 on Liver Fat Content, Cardiometabolic Risk Factors and Gut Microbiota Among Participants with MASLD
This clinical trial aims to investigate the effects of TOTUM-448, a mix of 5 plant extracts and choline, consumed at the daily regimen of two times per day, on liver fat content, cardiometabolic risk factors and gut microbiota…
- Trial name
- CARDIO-LIVER (NCT06704321)
- Testing
- TOTUM-448
- Where
- Canada
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Valbiotis
Insulin Resistance, Polycystic Ovary Syndrome
Lactobacillus Rhamnosus and PCOS Treatment
The effect of Lactobacillus rhamnosus supplementation on body weight, hyperandrogenism and insulin resistance in overweight and obesity women with Polycystic Ovary Syndrome will be analysed.
- Conditions
- Insulin Resistance, Polycystic Ovary Syndrome, Hyperandrogenism, Obesity
- Trial name
- ProjectPCOS (NCT03902301)
- Testing
- Lactobacillus group, Dietary group
- Where
- Poland
- Volunteers
- 80 people
- Sponsor
- Poznan University of Life Sciences
Obesity (Disorder)
Exercise Supervision Duration and Adherence in Obese Women
Obesity is one of the most common health problems worldwide and is associated with many chronic diseases. Regular physical activity is known to play an important role in weight control, balance, quality of life, and mental…
- Trial name
- NCT07152028
- Testing
- Exercise program with supervised and home-based components, Fully supervised exercise program
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Pamukkale University
Obesity, Polycystic Ovary Syndrome
Effect of Diet Plus Sibutramine on Hormonal and Metabolic Features in Overweight and Obese Women With PCOS
Studies on the effect of sibutramine, an anti-obesity drug, on hormonal and metabolic features of women with polycystic ovary syndrome (PCOS) are lacking.
- Trial name
- NCT00463112
- Testing
- Sibutramine
- Where
- Greece
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hippocration General Hospital
Polycystic Ovary, Obesity
Polycystic Ovary Syndrome and BETATROPHIN
This is an original study giving an information about the association body mass index, polycystic ovary syndrome and betatrophin.
- Trial name
- NCT04448730
- Testing
- serum marker levels
- Where
- Turkey (Türkiye)
- Volunteers
- 73 people
- Sponsor
- Hatice Akkaya
Obesity in Pregnancy, Maternal Comfort During Fetal Monitoring
EFFECT OF DİFFERENT POSİTİONS ON PAİN AND COMFORT DURİNG FETAL MONİTORİNG İN OBESE PREGNANT WOMEN
This study was conducted to understand how different body positions during fetal monitoring affect pain and comfort in obese pregnant women.
- Trial name
- NCT07379307
- Testing
- Maternal Positioning during NST
- Where
- Turkey (Türkiye)
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Diabetes, Weight Loss
De Por Vida: A Diabetes Risk Reduction Intervention for Hispanic Women
This pragmatic randomized clinical trial will assess the efficacy, cost, and sustainability of a culturally tailored weight-loss program targeting obese Hispanic women with pre-diabetes or T2D.
- Conditions
- Diabetes, Weight Loss, PreDiabetes, Obesity
- Trial name
- NCT03113916
- Testing
- Behavioural Lifestyle Intervention
- Volunteers
- 195 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Obesity, Diabetes
Fuel Utilization, Diet Composition, and Exercise in African American Women
African American women have a high prevalence of obesity and type 2 diabetes and do not optimally burn fat and carbohydrates in response to changes in these nutrients in their diets.
- Conditions
- Obesity, Diabetes, Insulin Resistance
- Trial name
- NCT04293367
- Testing
- High Intensity Interval Training (HIIT)
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Obesity
Effect of Weight Loss and Lifestyle Changes on Vascular Inflammatory Markers in Obese Women
Obesity is an independent risk factor for cardiovascular disease, which may be mediated by increased secretion of proinflammatory cytokines by adipose tissue.
- Trial name
- NCT00666874
- Testing
- lifestyle changes, Control - general information
- Where
- Italy
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Campania Luigi Vanvitelli
Breast Cancer, Obesity
Vitamin D, Diet and Activity Study
Experimental and human data suggests that vitamin D could protect against breast cancer. Overweight/obese individuals are at increased risk of low vitamin D levels.
- Conditions
- Breast Cancer, Obesity, Hypovitaminosis D
- Trial name
- ViDA (NCT01240213)
- Testing
- Vitamin D
- Where
- United States
- Volunteers
- 218 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Obese, Elevated Blood Pressure
Mat Pilates and Vascular Function in Obese Females
Obesity is associated with progressive decreases in arterial health and function. It is crucial to prevent or reduce the negative effects of aging on the vasculature by implementing appropriate lifestyle interventions, such as…
- Trial name
- NCT03907384
- Testing
- Mat Pilates training
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Marymount University
Cancer, Breast, Obesity, Abdominal
SCOPE-Chinese Women Study
This project examines the feasibility of a smartphone-based intervention to reduce obesity and breast cancer risk among Chinese women in China.
- Trial name
- SCOPE (NCT04326660)
- Testing
- SCOPE-Chinese Women
- Where
- 2 sites in United States, China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Morbid Obesity
Laparoscopic Sleeve Gastrectomy Plus Weight Watchers vs. Weight Watchers Alone in Underserved Minority Women
Obesity is a costly multi-etiology world disease of fat storage. Morbid obesity is defines as greater than 100 pounds overweight and/or greater than 200 % of ideal body weight.
- Trial name
- NCT01929850
- Testing
- Laparscopic Sleeve Gastrectomy, Weight Watchers Program
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Obesity
Effects of High-intensity Exercise With Hypoxia and Taurine Supplementation on Metabolic and Mitochondrial Parameters
The prevalence of obesity in Brazil is one of the highest in Latin America. As an inflammatory disease, obesity needs to be treated, and one of the best interventions is exercise.
- Trial name
- NCT06579508
- Testing
- Cycle ergometer
- Where
- 2 sites in Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Obesity
NMES Plus Hypocaloric Diet: Body Composition, Cardiometabolic Markers, Irisin and Betatrophin in Women With Obesity
This randomized controlled trial evaluated whether adding localized neuromuscular electrical stimulation (NMES) to an individualized hypocaloric diet changes serum irisin and betatrophin (ANGPTL8) concentrations, body composition…
- Trial name
- NCT07675382
- Testing
- Hypocaloric Diet, Neuromuscular Electrical Stimulation (NMES)
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Firat University
Obesity Complicating Childbirth, Obesity
The MODE Trial: Planned Caesarean Section Versus Induction of Labour for Women With Class III Obesity
Canadian guidelines recommend that women with a pre-pregnancy body mass index (BMI) at or above 40 kg/m2 deliver by their due date.
- Conditions
- Obesity Complicating Childbirth, Obesity, Labor Onset and Length Abnormalities, Pregnancy, High Risk
- Trial name
- MODE (NCT03985618)
- Testing
- Caesarean section, Induction of Labour
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Ottawa Hospital Research Institute
Morbid Obesity, Weight Loss
Meal-induced Thrombin Generation Before and After Gastric Bypass
The purpose of this study is to investigate harmful effects of intentional weight loss. Intentional weight loss has been linked to increased risk of cardiovascular disease in overweight individuals, but the link between…
- Trial name
- NCT03176615
- Testing
- Experimental diet
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Esbjerg Hospital - University Hospital of Southern Denmark
Obesity
Prevalence of Endometrial Abnormalities In Obese Women
It is known that women who are obese are at higher risk of endometrial cancer (cancer of the lining of the uterus or womb). The goal of this clinical research study is to find out how common abnormalities of the endometrium are…
- Trial name
- NCT00500591
- Testing
- Questionnaire
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Pregnancy, Obesity
Maternal Metabolism and Pregnancy Outcomes in Obese Pregnant Women
The purpose of this study is to study longitudinal changes in maternal metabolism and pregnancy outcomes in obese pregnant women.
- Trial name
- NCT02564250
- Where
- Norway
- Volunteers
- 150 people
- Sponsor
- Vestre Viken Hospital Trust
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