Clinical trials: Overweight or Obesity
Overweight or Obesity
Examination of Circumferential Reduction
The rationale for the selection of Outcome Measures is the compliance with FDA regulations as pertain to medical devices with a moderate level of risk of hazard leading to harm of the patient; firstly, the safety of the device in…
- Trial name
- NCT04451824
- Testing
- CL-100
- Where
- 3 sites in United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Contour Research
Obesity
Long-limb or Distal Gastric Bypass for Superobesity - Randomized Study
The main study objective: To evaluate long-limb gastric bypass (150 cm alimentary limb) vs. "distal" gastric bypass (common channel 150 cm) in the treatment of superobesity (BMI 50-60 kg/m2).
- Trial name
- NCT00821197
- Testing
- long-limb gastric bypass, distal gastric bypass
- Where
- Norway
- Volunteers
- 115 people
- Sponsor
- Oslo University Hospital
Oxidative Stress, Inflammation Biomarkers
Effect of a Food Supplement with Natural Extracts of Cocoa, Amaranth Seed and Ginger in Overweight or Obese Patients
Clinical trial, randomized, double-blind, controlled with a placebo group, 40 patients between 18 and 60 years of age, with the presence of overweight, will be divided into parallel groups, group A cocoa, amaranth seed and…
- Conditions
- Oxidative Stress, Inflammation Biomarkers, Obesity and Overweight
- Trial name
- NCT06769035
- Testing
- Cocoa, amaranth seed and ginger, Amaranth seed, Cocoa
- Where
- Mexico
- Volunteers
- 40 people
- Sponsor
- University of Guadalajara
Overweight and Obesity
Low-frequency High-Intensity Interval Training in Overweight or Obese Young Adults
Background: The relationship between the frequency of high-intensity interval training (HIIT) and the resultant adaptations is largely unclear.
- Trial name
- NCT03904810
- Testing
- Exercise intervention
- Where
- Hong Kong
- Volunteers
- 103 people
- Sponsor
- The University of Hong Kong
Obese or Overweight Healthy Volunteers
Clinical Study to Assess the Safety and Efficacy of ACV Moringa Effervescent Tablet Intake on Weight Management in Overweight and Class I Obese Study Participants
A Randomized, Double-Blind, Placebo-Controlled, Two-Arm, Single-Centre, Clinical Study to Evaluate the Safety and Efficacy of Intake of ACV Moringa on the Degree of Weight Change in Overweight and Class I Obese Study Participants
- Trial name
- NCT07098624
- Testing
- ACV Moringa Effervescent Tablets 4.3 g
- Volunteers
- 66 people
- Sponsor
- NovoBliss Research Pvt Ltd
Overweight or Obesity
Probiotic Influence on Obesity-Related Lipidemia
This study aims to investigate the effects of Bifidobacterium breve BBr60 on key health indicators in overweight and obese adults.
- Trial name
- NCT06305650
- Testing
- Probiotic
- Where
- China
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Wecare Probiotics Co., Ltd.
Healthy, Obesity
A Study in People With Overweight or Obesity to Compare How 2 Different Formulations of Survodutide Are Taken up by the Body
The primary objective of this trial is to assess bioequivalence of two formulations of survodutide (formulation A and formulation B6) after multiple-dose treatment in male and female trial participants living with overweight or…
- Conditions
- Healthy, Obesity, Overweight
- Trial name
- NCT07407348
- Testing
- Formulation A, Formulation B6
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Overweight , Obesity
A Study of SRSD384 in Overweight or Obese Participants
This is a two-part study, intended to investigate the safety, tolerability, characteristics of PK and PD of single SC dose of SRSD384 alone in overweight or obese participants (Part A) and in combination with tirzepatide in…
- Trial name
- NCT07557355
- Testing
- SRSD384 injection
- Where
- Australia
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Sirius Therapeutics Co., Ltd.
Metabolism and Nutrition Disorder, Obesity
Investigation of Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Dosing of NNC0174-0833 in Subjects With Obesity or Overweight
This trial is conducted in The United States of America. The aim of this trial is to investigate Safety, Tolerability, Pharmacokinetics (the exposure of the trial drug in the body) and Pharmacodynamics (the effect of the…
- Trial name
- NCT02958085
- Testing
- NNC0174-0833
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- Novo Nordisk A/S
Obesity, Diabetes
Effects of Prevena Therapy on Obese and or Diabetic Patients With Surgical Groin Sites
The purpose of the study is to determine the effects of Prevena therapy on decreasing groin surgical site infections in patients who are obese and /or diabetic having vascular surgery.
- Conditions
- Obesity, Diabetes, Peripheral Vascular Disease
- Trial name
- NCT01983215
- Testing
- Prevena vac
- Where
- United States
- Volunteers
- 276 people, healthy volunteers welcome
- Sponsor
- Dr. Jean E. Starr, MD
Obesity, Overweight
A Study to Investigate the Effect of LY4086940 Versus Placebo in Participants With Obesity or Overweight and Without Type 2 Diabetes
The purpose of this study, performed under the master protocol W8M-MC- CWMM (NCT06143956), is to evaluate the efficacy and safety of LY4086940 compared with placebo in participants without type 2 diabetes who have obesity or who…
- Trial name
- NCT07890376
- Testing
- LY4086940
- Where
- 46 sites in United States, Argentina
- Volunteers
- 460 people
- Sponsor
- Eli Lilly and Company
Obesity, Cardiovascular Diseases
High-intensity Exercise Training or Multidisciplinary Treatment in Extremely Obese Adolescents
The aim of the present study was to determine the effects of a multidisciplinary approach and intensity-controlled interval training on cardiovascular risk factors in overweight adolescents
- Trial name
- NCT00682266
- Testing
- intensity controlled interval training (AIT), Multidisciplinary approach (MTG)
- Where
- Norway
- Volunteers
- 54 people
- Sponsor
- Norwegian University of Science and Technology
Obesity in Diabetes, Type 2 Diabetes Mellitus (T2DM)
A Study to Evaluate the Efficacy and Safety of Once-Weekly MET097 in Adults With Obesity or Overweight and T2DM
This study is designed to test how well once-weekly MET097 (an ultra-long-acting GLP-1 receptor agonist) works to treat adults with obesity or overweight and type 2 diabetes mellitus (T2DM) compared to placebo.
- Trial name
- VESPER-2 (NCT06897202)
- Testing
- MET097 Injection
- Where
- 29 sites in United States
- Volunteers
- 133 people
- Sponsor
- Pfizer
Intermittent Fasting
Effects of Timed Restricted Eating on Body Composition, Metabolism, and Cardiovascular Health
This study is looking at whether eating all meals within a 6-hour window each day (called Time-Restricted Eating, or TRE) can improve body composition, metabolism, heart health, and blood markers over 12 weeks.
- Trial name
- NCT07574177
- Testing
- Time-Restricted Eating (TRE), Time-Restricted Eating with Intermittent Energy Restriction (TRE+IER)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of South Alabama
Overweight , Obesity
Phase 2 Study to Evaluate the Efficacy and Safety of MWN109 Injection in Non-Diabetic Participants With Overweight
This study is a multicenter, randomized, double-blind, placebo-controlled phase II study conducted in China. It aims to evaluate the efficacy and safety of MWN109 injection in non-diabetic overweight or obese participants.
- Trial name
- NCT07791537
- Testing
- MWN109 1, MWN109 2, MWN109 3
- Where
- China
- Volunteers
- 125 people
- Sponsor
- Shanghai Minwei Biotechnology Co., Ltd
Infertility, Female, Obesity
Effect of Lifestyle and/or Metformin Intervention on Pregnancy Outcome, A Pilot Randomized Controlled Trial
The purpose of pilot trial is to compare the efficacy of lifestyle intervention, metformin intervention, lifestyle combined with metformin intervention in improving assisted reproductive technology in non-polycystic ovary…
- Conditions
- Infertility, Female, Obesity, Insulin Resistance
- Trial name
- NCT03898037
- Testing
- weight loss intervention, metformin intervention
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Reproductive & Genetic Hospital of CITIC-Xiangya
Overweight, Obesity
A Study of LY3437943 in Chinese Participants With Obesity Or Overweight
The main purpose of this study is to learn about the safety and tolerability of LY3437943 when given to Chinese participants with overweight body mass index (BMI) or obesity.
- Trial name
- NCT05548231
- Testing
- LY3437943
- Where
- 2 sites in China
- Volunteers
- 32 people
- Sponsor
- Eli Lilly and Company
Low Back Pain
A Combined Lifestyle Intervention Delivered by Physio/exercise Therapists for Patients with Persistent Low Back Pain and Overweight or Obesity
Low back pain (LBP) is the leading cause of disability worldwide and is costly. Lifestyle factors, such as physical inactivity, stress, sleep, excess weight, and an unhealthy diet contribute to the burden of LBP and the…
- Trial name
- Back2Health (NCT06594796)
- Testing
- Combined lifestyle intervention and LBP care (physiotherapy, exercise therapy)
- Where
- Netherlands
- Volunteers
- 318 people
- Sponsor
- Willeke Boonstra
Overweight and Obesity
The Effect of Exercise and/or Diet on Health Related Parameters
The study evaluates the effect of exercise and/or diet during on body weight, body composition and health related blood parameters.
- Trial name
- NCT04100356
- Testing
- Exercise, Normal Diet, LCHF Diet
- Where
- Norway
- Volunteers
- 57 people
- Sponsor
- Atlantis Medical University College
Obesity
Gastric Bypass and Peripheral Activity of the Endocannabinoid System
The aim of the study is to precise the effect of a large amount of weight loss induced by gastric bypass on the endocannabinoid system (plasma and adipose tissue) of morbidly obese patients and to determine the influence of a…
- Trial name
- CCENDO (NCT01003873)
- Testing
- Evaluation of the endocannabinoid system, Biopsy of visceral and peripheral adipose tissue, Evaluation of metabolic parameters
- Where
- France
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux