Clinical trials: Oxidative Stress, completed
Cardiovascular Diseases, Aging
Cardio-vascular Protective Effects of Wolfberry in Middle-aged and Older Adults
This purpose of this study is to assess the impact of consuming wolfberry on cardiovascular risk in Singapore's middle-aged and older adults.
- Trial name
- NCT03535844
- Testing
- Wolfberry, Healthy diet
- Where
- 2 sites in Singapore
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Type 2 Diabetes, Prediabetes
Seum Bile Acid Profile in Type 2 Diabetes and Association Between Bile Cid Profile and Adipokine or Oxidative Stress
"The goal of this work is to critically test the hypothesis that there exists a different profile of bile acids (BAs) in patient with type 2 diabetes mellitus (T2DM) compared with normal controls.
- Conditions
- Type 2 Diabetes, Prediabetes, Non-alcoholic Fatty Liver Disease, Metabolic Syndrome
- Trial name
- NCT02650830
- Where
- South Korea
- Volunteers
- 362 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Inflammation, Oxidative Stress
An Evaluation of Zinc Status Biomarkers
The purpose of this study is to determine the effect of a moderate decrease in dietary zinc on DNA strand breaks and other cellular zinc biomarkers.
- Trial name
- NCT02861352
- Testing
- Diet zinc
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- UCSF Benioff Children's Hospital Oakland
Type 2 Diabetes Mellitus
Role of Allopurinol on Oxidative Stress and Mitochondrial Alterations in Skeletal Muscle of Diabetic Patients
Our recent data in mice have demonstrated a key role of xanthine oxidase in hyperglycemia-induced by Reactive oxygen species production, and a preventive role of allopurinol (inhibitor of xanthine oxidase) on the keeping of…
- Trial name
- DIAXO (NCT02533648)
- Testing
- 2 capsules of allopurinol 150 mg daily for 3 month, 2 capsules of lactose daily for 3 month
- Where
- France
- Volunteers
- 31 people
- Sponsor
- Hospices Civils de Lyon
Hepatitis C, Oxidative Stress
Blood Antioxidant Status in Chronic Hepatitis C Patients Before and After Antioxidant Supplementation: a Randomized Clinical Trial
The objective of the present study is to evaluate the antioxidant status in the blood of HCV patients treated with pegylated interferon (2a 1.5 ug/kg; 2b 180 ug) combined with ribavirin (1000 to 1250 mg) before and after…
- Trial name
- HepCAntSup (NCT00983164)
- Testing
- Antioxidant Supplementation
- Where
- 3 sites in Brazil
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Universidade do Sul de Santa Catarina
Healthy Men, Healthy Women
Garlic Intake And Biomarkers Of Cancer Risk
This study is being done to study the healthful benefits of eating garlic. Previous studies suggest that garlic may help prevent cancer.
- Trial name
- NCT01293591
- Testing
- Control, Garlic treatment
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- USDA Beltsville Human Nutrition Research Center
Oilgohydramnios
Role of Antioxidants in Unexplained Oligohydramnios,A Randomized Trial
To predict the effect of antioxidants in cases of oligohydramnios
- Trial name
- ao&uoh (NCT01990690)
- Testing
- anti oxidant omega 3
- Where
- Egypt
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Woman's Health University Hospital, Egypt
Endothelial Dysfunction
High Inspiratory Oxygen Fraction on Endothelial Function in Healthy Volunteers
The frequency of preoperative cardiac ischemia and the 30-days postoperative mortality is much higher than previously assumed, with approximately 10 % of patients undergoing non-cardiac surgery suffering from postoperative…
- Trial name
- NCT02342405
- Testing
- 80% oxygen, 30% oxygen
- Where
- Denmark
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Zealand University Hospital
Preterm Infants
Perenteral Nutrition and Oxidative Stress in Preterm Infants
In an effort to decrease the load of peroxides in TPN solutions, multiple studies examined different strategies such as photo-protection, adding multivitamins to the lipid emulsion rather than to the dextrose-amino acid…
- Trial name
- NCT00611546
- Testing
- Photo-protection, Photo-exposure
- Volunteers
- 80 people
- Sponsor
- Mansoura University
Endothelial Dysfunction, Endothelial Function
Cycling, Air Pollution and Health
Introduction: Cycling is currently promoted at the municipal, provincial and national level as a form of active transportation that increases physical activity while at the same time reducing traffic congestion, traffic-related…
- Conditions
- Endothelial Dysfunction, Endothelial Function, Cardiovascular Physiological Phenomena
- Trial name
- CAPaH (NCT01708356)
- Testing
- Cycling on a residential route
- Where
- Canada
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Overweight and Obesity, Chronic Disease
Influence of Genetic and Physiological in Weight Loss
The study focuses on the influence of polymorphism in the FTO genes rs9939609 and PPARᵧ Pro12Ala, oxidative stress and systemic inflammation on changes in body composition and rest metabolism induced by HIIT and continuous…
- Trial name
- NCT03568773
- Testing
- High-intensity interval training, Aerobic exercise moderate intensity, Control Group
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Federal University of Paraíba
Hypercholesterolemia
Combination Treatment With Green Tea Extract and Statins in Patients With Hypercholesterolemia
There is a positive correlation between serum's cholesterol levels and death from cardiovascular disease, especially coronary artery disease. The reduction of plasma lipids levels is one of the main goals of prevention.
- Trial name
- GTE-Stat (NCT00944827)
- Testing
- Green Tea Extract - Catechins
- Where
- Greece
- Volunteers
- 40 people
- Sponsor
- University of Thessaly
Parenteral Nutrition
Study Comparing a Soybean Oil-Based With an Olive Oil-Based Lipid Emulsion in ICU Patients Requiring TPN
Many hospitalized patients who are malnourished or not eating receive intravenous feeding or total parenteral nutrition (TPN). Despite improving nutrition, TPN may increase the risk of infections and hospital complications.
- Trial name
- TPN2 (NCT00672854)
- Testing
- ClinOleic 20% Intravenous Emulsion, Intralipid, 20% Intravenous Emulsion
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Emory University
Myocardial Infarction, Diet
Dietary Antioxidants and Chronic Diseases-The Swedish National March Cohort
Dietary antioxidants might protect from the development of chronic diseases by reducing levels of oxidative stress. The investigators therefore investigated the effect of dietary Non Enzymatic Antioxidant Capacity, which measures…
- Conditions
- Myocardial Infarction, Diet, Osteoarthritis
- Trial name
- NCT03350568
- Testing
- Total dietary NEAC assessed at baseline
- Where
- Sweden
- Volunteers
- 43,880 people
- Sponsor
- Karolinska Institutet
Vascular Disease, Endothelial Dysfunction
Effects of Almonds on Vascular Reactivity in Patients With Coronary Artery Disease
This is a study of the effects of 3 oz almonds added daily to a National Cholesterol Education Program Therapeutic Lifestyle Changes (TLC) diet in improving endothelial function in patients with Coronary Artery Disease.
- Conditions
- Vascular Disease, Endothelial Dysfunction, Heart Disease, Cardiovascular Diseases
- Trial name
- NCT00782015
- Testing
- Almonds
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Tufts University
Type 1 Diabetes
Muscle Oxygenation, Type 1 Diabetes, and Glycated Hemoglobin
Most of the studies concerning aerobic fitness in Type 1 diabetic patients noted a relationship between impaired aerobic fitness and high glycated haemoglobin (HbA1c) levels, reflecting poor long term glycaemic control.
- Trial name
- OXYDIAB (NCT02051504)
- Testing
- Incremental maximal exercise, Oral Glucose Tolerance Test, Muscle biopsy
- Where
- France
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Oxidative Stress, Inflammation
Vitamin D, Oxidative Stress and Inflammation in Hemodialysis
Vitamin D deficiency is now considered a global problem in general population, but it seemed to be more prominent in chronic kidney disease (CKD) patients, especially those on regular hemodialysis.
- Conditions
- Oxidative Stress, Inflammation, Vitamin D Deficiency
- Trial name
- NCT05460338
- Testing
- Cholecalciferol
- Where
- Egypt
- Volunteers
- 25 people
- Sponsor
- Ain Shams University
Oxidative Stress
Clinical Trial to Investigate the Efficacy and Safety of LN-OS-22 on Oxidative Stress and Systemic Inflammation in Overweight and Obese Population.
The present clinical investigation has been proposed to further substantiate the evidence of the antioxidant and anti-inflammatory activity of the extract in the healthy adult population with BMI ranging from ≥25.0 kg/m2 and ≤…
- Trial name
- NCT05404217
- Testing
- LN-OS-22, Maltodextrin
- Where
- 3 sites in India
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Vedic Lifesciences Pvt. Ltd.
Sarcopenia, Mitochondrial DNA
Association of Uremic Sarcopenia and Mitochondrial Copy Number and Its Clinical Correlates
Sarcopenia is the decline of muscle mass and strength with age. Evidence suggests that oxidative stress and molecular inflammation play important roles in age-related muscle atrophy.
- Trial name
- NCT03929458
- Where
- Taiwan
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Tungs' Taichung Metroharbour Hospital
Air Pollution
The Effect of Juice Types on the Responses to Air Pollution
The study hypothesis is that drinking different juices will affect the body's responses to air pollution. Subjects will be exposed to air pollution during a 2-hour car ride on the NJ (New Jersey) Turnpike.
- Trial name
- NCT02027415
- Testing
- Beet juice, Orange juice
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.