Clinical trials: Oxidative Stress, completed
Arterial Stiffening, Aging
Sex Hormones and Atherosclerosis Prevention in Perimenopausal Women
The purpose of this study is to find out why women's arteries stiffen as they go through menopause, and how this is affected by estrogen loss.
- Conditions
- Arterial Stiffening, Aging, Menopause
- Trial name
- SHAPE (NCT00608062)
- Testing
- GnRHant - Ganirelix acetate, Transdermal estradiol patch
- Where
- United States
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Autism Spectrum Disorders
Oxidative Stress and Vitamin D Levels in Autism Spectrum Disorders
Oxidative Stress and Vitamin D Levels in Autism Spectrum Disorders
- Trial name
- NCT06983379
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Mardin Artuklu University
Myelodysplastic Syndrome, Secondary Acute Myeloid Leukemia
Plasmatic L-AScorbic Acid in MYelodyplastic Syndroms and Controls
Myelodysplastic syndromes (MDS) is a group of heterogeneous diseases characterised by the clonal evolution of dysplastic hematopoietic stem cells.
- Trial name
- PLASMYC (NCT02809222)
- Testing
- Samples, Quality of life questionnaire
- Where
- 2 sites in France
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- University Hospital, Tours
Colorectal Neoplasms
Immunological and Oxidative Stress Response in Relation to Abdominal Cancer Surgery
The aim of this study is to characterize the systemic stress response (SSR) induced in patients undergoing colorectal cancer (CRC) surgery. The project is a clinical prospective study.
- Trial name
- IMOX (NCT03473327)
- Volunteers
- 37 people
- Sponsor
- Zealand University Hospital
Type2 Diabetes
The Effect of Hypoxia on Type 2 Diabetes and Weight Loss
The number of people with type 2 diabetes mellitus (T2DM) continuing to rise, this pandemic is expected to reach 700 million people by 2045.
- Trial name
- NCT05147116
- Testing
- Sleeping in a tent
- Where
- United Kingdom
- Volunteers
- 22 people
- Sponsor
- University of Portsmouth
Cystic Fibrosis
Choline Nutritional Status Of Children With Cystic Fibrosis X-Sectional Study
Cystic fibrosis (CF) is the most common lethal, inherited disorder among Caucasians. Choline is an essential vitamin and as a methyl donor is critically needed to support the normal metabolism.
- Trial name
- NCT01150136
- Where
- Canada
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Effect of High Protein Diet on Endoplasmic Reticulum Stress
Effect of Protein on Endoplasmic Reticulum Stress
This study was planned to provide information about the effect of short-term high protein diet (HPD) feeding on endoplasmic reticulum stress. The definition of HPDs cannot be determined exactly.
- Trial name
- NCT06621901
- Testing
- High Protein Diet, Normal Protein Diet
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Diabetes
Water-soluble Ubiquinol Supplementation on Blood Glucose, Lipids, Oxidative Stress, and Inflammation in Diabetes
Diabetes is considered an oxidative stress and a chronic inflammatory disease. Coenzyme Q10 (ubiquinone) is recognized as a lipid soluble antioxidant.
- Trial name
- NCT02622672
- Testing
- water-soluble ubiquinol
- Volunteers
- 50 people
- Sponsor
- Yeh
Vascular Diseases, Impaired Glucose Tolerance
Effects of Dietary Ingredients on Vascular Function
The main aim of the study is to investigate the effects of dietary ingredients (polyphenols and carotenoids) on vascular function during acute glucose load.
- Trial name
- NCT02158481
- Testing
- A capsule containing both polyphenols and carotenoids
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- Unilever R&D
Cardiovascular Diseases, Hypertension
Mitochondria Oxidative Stress and Vascular Health Study
Cardiovascular diseases (CVDs) are the number one cause of death in America and most of the post-industrial world. Hypertension is a leading risk factor for CVDs including stroke, myocardial infarction, and heart failure.
- Conditions
- Cardiovascular Diseases, Hypertension, Racism, Vascular Diseases
- Trial name
- MOVHS (NCT05561556)
- Testing
- MitoQ
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Auburn University
Muscle Damage
Recovery Kinetics Following Eccentric Exercise
The aim of this study will be to investigate the recovery kinetics of neuromuscular fatigue, muscle microtrauma indicators, performance and oxidative stress factors after three different exercise induced muscle damage (EIMD)…
- Trial name
- NCT04733911
- Testing
- 75 eccentric contractions, 150 eccentric contractions, 300 eccentric contractions
- Where
- Greece
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Heart Failure
Effects of Chocolate in Patients With Chronic Heart Failure
The aim of the present study is to investigate whether in patients with chronic heart failure endothelial dysfunction and baroreceptor function is altered by ingestion of a flavonoid-rich dark chocolate in comparison to placebo…
- Trial name
- NCT00538941
- Testing
- Nestlé Noir intense 40 grx2
- Where
- Switzerland
- Volunteers
- 22 people
- Sponsor
- University of Zurich
Oxidative Stress, Inflammation
Inflammatory Stress and Periodontal Tissue Destruction
Metabolic syndrome and periodontitis are diseases that lower the quality of life and their incidence rates are increasing. Since both of these diseases are associated with systemic inflammation and insulin resistance, they may be…
- Trial name
- NCT06092853
- Testing
- Gingival crevicular fluid (GCF) and serum samples
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Age Related Symptoms, Age Related Quality of Life Issues
UCSD Q10 and Aging Study
Goal: The investigators propose to test the feasibility of giving the supplement coenzyme Q10 (Q10) improves symptoms and subjective health in an aging population.
- Trial name
- NCT02012322
- Testing
- Coenzyme Q10
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Aging, Sarcopenia
Effect of Creatine+HMB Supplementation in Physically Active Older Adults
Sarcopenia (SAR) is the loss of muscle strength and mass caused by aging. It is accompanied by a progressive decline in physical and cognitive abilities, increasing the risk of falls.
- Conditions
- Aging, Sarcopenia, Nutrition, Healthy
- Trial name
- CRESHARE (NCT05951439)
- Testing
- CRE + HMB
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidad de Burgos
Aging, Muscle Damage
Eccentric Exercise and Oxidative Stress
The purpose of the present investigation is to compare the responses and adaptations of young and elderly individuals to repeated eccentric exercise in regards to muscle function and redox homeostasis in a side-by-side comparison.
- Conditions
- Aging, Muscle Damage, Oxidative Stress
- Trial name
- NCT01728675
- Testing
- Exercise
- Where
- Cyprus
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- European University Cyprus
Diabetes, Gestational, Insulin Resistance
Metformin in Gestational Diabetes Mellitus
Gestational diabetes (GDM) is a condition that manifests as high blood sugar levels (hyperglycemia) during pregnancy in previously healthy women.
- Trial name
- MetGDM (NCT00681460)
- Testing
- human recombined insulin, metformin
- Where
- Poland
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- K. Marcinkowski University of Medical Sciences
Non Insulin Dependent Diabetes
Curcumin Supplementation and Patients With Type 2 Diabetes
Diabetes mellitus is the most common endocrine disorder, causes many complications such as micro- and macro-vascular diseases. Various kinds of antidiabetic drugs have been developed, but most of them have side effects.
- Trial name
- NCT02529982
- Testing
- Curcumin
- Where
- Iran
- Volunteers
- 44 people
- Sponsor
- National Nutrition and Food Technology Institute
Heart Arrest
Oxidative Stress and Cardiac Arrest
Cardiac arrest is a major health problem reaching 375000 cases in Europe each year. Only 5 to 31 % survive after an out of hospital cardiac arrest (OHCA). The main complication after OHCA is the anoxic encephalopathy.
- Trial name
- NCT00888966
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Institut d'Anesthesiologie des Alpes Maritimes
Diabetes Mellitus Type 2, Overweight and Obesity
Glycemic Variability Comparing Two vs Five Meals in Type 2 Diabetes
The frequency of meals is a very important aspect of nutrition, with profound effects on human health and in life expectancy. Excessive energy consumption is totally associated with a significant increase in the incidence of…
- Conditions
- Diabetes Mellitus Type 2, Overweight and Obesity, Meal Time
- Trial name
- NCT04127994
- Testing
- Comparing 3 versus 5 meals in type 2 diabetes patients
- Where
- Mexico
- Volunteers
- 50 people
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
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