Clinical trials: Oxidative Stress, completed
Metabolic Syndrome (MetS), Psychiatric Disorders
The Impact of the Mediterranean Diet on Anthropometric Indices, Lipid Profiles, Energy Metabolism Signaling Proteins and Inflammatory Cytokines in Psychiatric Patients With Metabolic Syndrome
Background: Dietary modifications, like changing macronutrient distribution and improving food quality, are the main therapeutic approaches for managing oxidative stress, inflammation, and metabolic syndrome.
- Conditions
- Metabolic Syndrome (MetS), Psychiatric Disorders, Mediterranean Diet, Inflammatory Cytokines
- Trial name
- NCT07164014
- Testing
- Mediterranean diet, Hospital diet
- Where
- Saudi Arabia
- Volunteers
- 144 people
- Sponsor
- King Saud University
Hyperoxia, Perioperative Care
Perioperative Hyperoxia vs Normoxia Biomarker Trial
This single-center randomized interventional study evaluated the biological effects of two perioperative oxygen strategies in adults undergoing elective laparoscopic lower abdominal surgery under standardized general anesthesia.
- Conditions
- Hyperoxia, Perioperative Care, Oxidative Stress, Endothelial Glycocalyx Injury
- Trial name
- NCT07525661
- Testing
- Perioperative Oxygen Strategy - Normoxia, Perioperative Oxygen Strategy-Hyperoxia
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Istanbul University
Atrial Fibrillation, Heart Failure, Diastolic
Atrial Fibrillation Ablation
Objective. Atrial fibrillation (AF) recurrence after catheter ablation (CA) is a relevant clinical problem. Methods. 123 patients with paroxysmal AF will be identified and screened for participation in this randomized…
- Trial name
- NCT03410966
- Testing
- trans cateheter ablation
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- University of Campania Luigi Vanvitelli
Obstructive Sleep Apnea (OSA), Sleep Apnea Syndrome, Obstructive
Empagliflozin and CPAP in Adults With Heart Failure and Obstructive Sleep Apnea.
The goal of this randomized clinical trial was to evaluate the effects of empagliflozin, a sodium-glucose cotransporter-2 inhibitor (SGLT2i) on sleep and cardiac outcomes in adults with heart failure (HF) and obstructive sleep…
- Conditions
- Obstructive Sleep Apnea (OSA), Sleep Apnea Syndrome, Obstructive, Heart Failure
- Trial name
- HF(L)OSA (NCT07556094)
- Testing
- Empagliflozin, Continuous Positive Airway Pressure (CPAP)
- Where
- Poland
- Volunteers
- 70 people
- Sponsor
- Medical University of Bialystok
Metabolic Syndrome
Dietary Intervention in Persons With Metabolic Syndrome
Individuals diagnosed with metabolic syndrome are at a two-fold risk for developing cardiovascular disease. The investigators must identify strategies that can abort the development of cardiovascular disease.
- Trial name
- MetLDI (NCT03836651)
- Testing
- Dietary Antioxidant (V8® Low Sodium 100% vegetable juice), Control group
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- Martha Biddle
Skin Condition, Anti Oxidative Stress
Investigation of the Efficacies of Multi Berries Juice on Anti Oxidant Effect and Improvement of Skin Conditions
To assess multi berries juice on anti-oxidant effect and skin condition improvement
- Trial name
- NCT04878523
- Testing
- multi berries juice
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- TCI Co., Ltd.
Oxidative Stress, Inflammation
Oxytocin for Oxidative Stress and Inflammation
Naval Special Warfare (NSW) operators are exposed to a variety of extreme environmental conditions and intense physical demands.
- Trial name
- NCT04732247
- Testing
- Oxytocin nasal spray
- Where
- 3 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Florida Institute for Human and Machine Cognition
Sleep Apnea Syndromes, Oxidative Stress
Efficacy of Continuous Positive Airway Pressure in Reducing Oxidative Stress in Individuals With Sleep Apnea
Sleep-disordered breathing (SDB) is a condition in which a person experiences frequent breathing pauses during sleep, also known as sleep apnea.
- Conditions
- Sleep Apnea Syndromes, Oxidative Stress, Cardiovascular Diseases
- Trial name
- SASS (NCT00607893)
- Testing
- Continuous Positive Airway Pressure (CPAP)
- Where
- United States
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Case Western Reserve University
Allergic Asthma
Study on the Role of Treatment With Vitamin E on Asthmatic Responses in Allergic Asthmatics
Asthma is a common respiratory disease of unknown etiology which currently affects approximately 7.5 % of the adult population ( ). Asthma is an inflammatory disorder of the airways.
- Trial name
- NCT00581048
- Testing
- Natural source d-α-tocopheryl acetate
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Vanderbilt University
Normal Tension Glaucoma, Bilirubin; Defect, Excretion
Serum Bilirubin Levels in Normal-tension Glaucoma
Purpose: To analyze the relationship between normal-tension glaucoma (NTG) and serum bilirubin levels. Materials and Methods: This research included 38 patients with NTG and 38 healthy controls with similar age and sex…
- Trial name
- NCT03387306
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Trakya University
Chemotherapy, Colorectal Cancer
Zinc Supplementation on Markers of Oxidative Stress in Post Operative Colorectal Cancer During Chemotherapy Cycles
Objective: To determine the oxidative stress during cycles of chemotherapy in patients after surgery for colorectal cancer, with or without oral zinc supplementation.
- Trial name
- NCT02106806
- Testing
- Zinc
- Where
- Brazil
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Oxidative Stress, Inflammation
Antioxidant and Immune Effects of Vitamin K2
The aim of the study is to obtain insight into a dose-dependent effect of vitamin K2 on oxidative stress and specific markers of the immune system.
- Trial name
- ProteK2t (NCT05675163)
- Testing
- Vitamin K2
- Where
- Netherlands
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- NIZO Food Research
Breast Cancer, Breast Carcinoma
Evaluation of Ocoxin®-Viusid® in Breast Cancer
The purpose is to determine the efficacy of the nutritional supplement Ocoxin-Viusid oral solution (OV) in the reduction of acute toxicity of Chemotherapy (CT) treatment with patients with breast carcinoma.
- Conditions
- Breast Cancer, Breast Carcinoma, Adriamycin Toxicity, Cyclosporine Toxicity
- Trial name
- NCT03576521
- Testing
- CT + Ocoxin-Viusid
- Where
- Cuba
- Volunteers
- 120 people
- Sponsor
- Catalysis SL
Lymphoma
S8516-S8736-S9125-S9240 Research Study of Genes in Tissue Samples From Patients With B-cell Non-Hodgkin Lymphoma
RATIONALE: Studying samples of tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer.
- Trial name
- NCT00985699
- Testing
- polymorphism analysis, laboratory biomarker analysis, pharmacogenomic studies
- Volunteers
- 337 people
- Sponsor
- SWOG Cancer Research Network
Oxidative Stress
Comparison of Oxidants and Antioxidants in Breastmilk Under Different Anesthesia Protocols
The goal of this observational study is to determine in women undergoing cesarean section if total oxidant status and total antioxidant status in breastmilk taken at the 6th hour postoperatively changes between general and…
- Trial name
- NCT06811714
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Duzce University
Type 1 Diabetes Mellitus
The Effect of Uric Acid Lowering in Type 1 Diabetes
Patients with type 1 diabetes mellitus (T1DM) are at high risk of developing kidney complications potentially leading to end stage renal disease.
- Trial name
- NCT02344602
- Testing
- Febuxostat
- Where
- Canada
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Premature Birth
Oxidative Stress in Women Treated With Atosiban for Impending Preterm Birth
Oxidative stress is recognized as a important factor in the pathogenesis premature birth. Preterm birth is defined as delivery before 37 completed weeks of gestation and it is the leading cause of neonatal morbidity and…
- Trial name
- NCT03570294
- Testing
- Atosiban
- Where
- Poland
- Volunteers
- 64 people
- Sponsor
- Polish Mother Memorial Hospital Research Institute
Low Back Pain, Chronic Disease
Myofascial Release and Kinesio Taping on Autonomic Nervous System in Low Back Pain
The purpose of this current randomized clinical trial is to determine the effects of myofascial soft tissue release and kinesio taping on disability, pain, quality of life, autonomic nervous system and oxidative stress indicators…
- Trial name
- I (NCT02067494)
- Testing
- Myofascial Soft Tissue Release, Kinesio taping treatment
- Where
- Spain
- Volunteers
- 64 people
- Sponsor
- Universidad de Almeria
Very Low Birth Weight Baby, Premature Birth
Human-derived Human Milk Fortifiers (H2MF), Gut Microbiota and Oxidative Stress in Premature Infants
This is a randomized controlled trial of a human-derived human milk fortifier (H2MF) vs standard bovine-derived human milk fortifier (HMF) evaluating fecal microbiota and fecal and urinary biomarkers of oxidative stress in…
- Conditions
- Very Low Birth Weight Baby, Premature Birth, Microbial Colonization, Oxidative Stress
- Trial name
- NCT03214822
- Testing
- H2MF
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of Manitoba
Maxillary Expansion
Rapid Maxillary Expansion Related Oxidative Stress and Periodontal Results
The aim of this study was to investigate the effects of rapid maxillary expansion on local and systemic oxidative stress levels.
- Trial name
- NCT06937775
- Testing
- Periodontal measurements (plaque index, gingival index and probing pocket depth scores ), Biochemical Sample Supply (Collection of serum and saliva samples), Rapid maxillary expansion with Hyrax appliance
- Volunteers
- 35 people
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
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