Clinical trials: Oxidative Stress, completed
Bypass Complication, Cardioplegia Solution Adverse Reaction
Investigation of Myocardial Protection Level With Specific Cardioplegia Methods in Cardiac Surgery
Investigating the myocardial effects of cold blood cardioplegia and del nido cardioplegia solution, which are routinely used in clinical practice, will contribute to the studies in the literature on the safety and efficacy of…
- Conditions
- Bypass Complication, Cardioplegia Solution Adverse Reaction, Endothelial Degeneration, Oxidative Stress
- Trial name
- NCT05603429
- Testing
- Endocan, E-Selectin, TNF-alpha, Total Oxidant and Antioxidant Status
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people
- Sponsor
- Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital
Temporomandibular Disorder, Oxidative Stress
Evaluation of Oxidative Stress and Inflammation Markers in Temporomandibular Disorders
Background: The occurrence of many diseases has been associated with oxidative stress and disruption of antioxidant mechanisms. Temporomandibular Joint(TMJ) Disorders are also thought to develop with the onset of the destructive…
- Conditions
- Temporomandibular Disorder, Oxidative Stress, Inflammation
- Trial name
- NCT05985733
- Testing
- Biochemical analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
Oxidative Stress
Correlation Between Oxidative Stress Status and COVID-19 Severity
During the new COVID-19 pandemic physicians all over the world have faced different challenges .Oxidative stress is a probable cause of multi organ failure in this setting which never has been evaluated in COVID-19 infection to…
- Trial name
- NCT04375137
- Testing
- Oxidative Stress ELISA Kit
- Where
- Iran
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University of Medical Sciences
Oxidative Stress, Cardiovascular Diseases
Effects of Trehalose and Polyphenols in Vasculopathic Patients
Peripheral arterial disease (PAD) is an important manifestation of systemic atherosclerosis and is characterized by obstruction of the arteries of the lower extremities.
- Trial name
- NCT04061070
- Testing
- Supplementation with mix of threalose plus polyphenols, No Supplementation with mix of threalose plus polyphenols
- Where
- 2 sites in Italy
- Volunteers
- 80 people
- Sponsor
- University of Roma La Sapienza
Oxidative Stress, Inflammation
Antioxidant and Immune Effects of Vitamin K2
The aim of the study is to obtain insight into a dose-dependent effect of vitamin K2 on oxidative stress and specific markers of the immune system.
- Trial name
- ProteK2t (NCT05675163)
- Testing
- Vitamin K2
- Where
- Netherlands
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- NIZO Food Research
Oxidative Stress
Circadian Modulation of Grape Consumption and Oxidative Stress Response
This study investigated the effects of time-of-day of grape consumption on high-fat meal-induced oxidative stress.
- Trial name
- NCT05873530
- Testing
- Grape
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Idaho State University
Gingivitis; Chronic, Oxidative Stress
Efficacy of Green and White Tea Extract Mouthwashes in the Management of Plaque-induced Gingivitis: A Clinical and Biochemical Study
Background and objective: Tea is the second most consumed drink in the world after water. Gingivitis is among the most common infectious diseases.
- Conditions
- Gingivitis; Chronic, Oxidative Stress, Inflammation
- Trial name
- NCT05861206
- Testing
- GT-MW group (5% Green tea), WT-MW group (5% White tea),EO-MW group (Listerine mouthrinse), CHX-MW group (0.12% CHX, as a positive control group)
- Where
- Turkey (Türkiye)
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Yağmur Saraç Gül
Inflammation, Mental Health Wellness 1
Health Effects of Traditional Indigenous Chokeberry
American Indian populations continue to suffer disproportionately from health problems including such nutrition-related chronic diseases as diabetes and heart disease.
- Conditions
- Inflammation, Mental Health Wellness 1, Oxidative Stress
- Trial name
- NCT05410327
- Testing
- Chokeberry (Aronia melanocarpa) juice
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of North Dakota
Oxidative Stress, Infertility
Thiol/Disulphide Homeostasis in Unexplained Infertility
The aim in this study is to determine whether there is a relationship between Thiol / Disulphide levels in primary infertile patients and comparing them with infertile patients and the control group.
- Conditions
- Oxidative Stress, Infertility, Antioxidative Stress
- Trial name
- NCT05628766
- Testing
- complete blood count
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Siirt University
Oxidative Stress
Clinical Trial to Investigate the Efficacy and Safety of LN-OS-22 on Oxidative Stress and Systemic Inflammation in Overweight and Obese Population.
The present clinical investigation has been proposed to further substantiate the evidence of the antioxidant and anti-inflammatory activity of the extract in the healthy adult population with BMI ranging from ≥25.0 kg/m2 and ≤…
- Trial name
- NCT05404217
- Testing
- LN-OS-22, Maltodextrin
- Where
- 3 sites in India
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Vedic Lifesciences Pvt. Ltd.
Oxidative Stress, Inflammation
Antioxidant Effect of Ozonated Vegetable Oil and Vitamins in Moderately Active Subjects
The purpose of this pilot study is to evaluate the antioxidant effect of a nutraceutical formulation based on vegetable oil and vitamin complex (vitamin K2 and vitamin B9) in subjects with the same level of physical activity (LAF…
- Trial name
- ANTIOX001 (NCT05592509)
- Testing
- Ozonized vegetable oil with vitamines
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- S&R Farmaceutici S.p.A.
Peri-Implantitis, Bone Loss in Jaw
An Evaluation of Salivary Oxidant and Antioxidant Levels in Peri-implant Health and Disease
Objectives: Inflammatory lesions develop in the tissues surrounding implants are referred to as peri-implant diseases. Oxidants, play a role in inflammatory lesions.
- Conditions
- Peri-Implantitis, Bone Loss in Jaw, Dental Implant Failed, Dental Implant Failure Nos
- Trial name
- NCT05724706
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Biruni University
Oxidative Stress, Inflammation
Vitamin D, Oxidative Stress and Inflammation in Hemodialysis
Vitamin D deficiency is now considered a global problem in general population, but it seemed to be more prominent in chronic kidney disease (CKD) patients, especially those on regular hemodialysis.
- Conditions
- Oxidative Stress, Inflammation, Vitamin D Deficiency
- Trial name
- NCT05460338
- Testing
- Cholecalciferol
- Where
- Egypt
- Volunteers
- 25 people
- Sponsor
- Ain Shams University
Oxidative Stress
Drinking Effect of Electrolyzed Alkaline Reduced Water on Oxidative Stress and Fatigue After Intense Exercise
The goal of this clinical trial is to test the drinking effect of electolyzed alkaline reduced water (ARW) generated from alkaline ionizer (CGM MWPI-2101) on oxidative stress and fatigue after high-intensity exercise in healthy…
- Trial name
- NCT05673395
- Testing
- Electrolyzed alkaline reduced water generator
- Where
- South Korea
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Kyu Jae Lee
Endothelial Dysfunction, Oxidative Stress
Creatine Monohydrate Supplementation and Vascular Endothelial Health
To determine the effects of 4 weeks of creatine monohydrate supplementation on markers of macrovascular and microvascular function, cognitive performance, and physical performance.
- Trial name
- NCT05014659
- Testing
- Creatine monohydrate
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Florida State University
Oxidative Stress, Inflammation
Innovative Biotechnological Production of Antioxidant Products
Several natural compounds have been explored as immune-boosting, antioxidant, and anti-inflammatory dietary supplements. Amongst them, hydroxytyrosol a natural antioxidant found in olive products, and endemic medicinal plants…
- Conditions
- Oxidative Stress, Inflammation, Body Weight, Homocystine; Metabolic Disorder
- Trial name
- Antiox-Plus (NCT05679310)
- Testing
- Hydroxytyrosol/Essential oils
- Where
- Greece
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Ioannina
Oxidative Stress
Saturation Targets and Resuscitation in Preterm Trial
The purpose of this research project is to determine if use of optimized target oxygen strategy during delivery room resuscitation can reduce oxidative stress in premature newborns.
- Trial name
- STARTPreterm (NCT03115463)
- Testing
- Titration of oxygen during neonatal resuscitation
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- University of Texas Southwestern Medical Center
Major Depressive Disorder, Oxidative Stress
Near-infrared Radiation-transcranial Photobiomodulation for Major Depressive Disorder
This study was designed to be a 3 year, 3 phases project, and will explore the therapeutic effects from near-infrared transcranial photobiomodulation (NIR tPBM) in major depressive disordered human subjects, and it's biological…
- Trial name
- NCT04619121
- Testing
- NIR-tPBM
- Where
- Taiwan
- Volunteers
- 48 people
- Sponsor
- China Medical University Hospital
Craving, Mastication Disorder
Effects of Non-invasive Neuromodulation on Food Desire, Chewing Pattern, Executive Functions and Oxidative Stress.
From the change in self-regulation, memory is inhibited, allowing individuals to suppress or ignore unwanted or outdated associations and thus help to filter information relevant to dietary goals from irrelevant information.
- Conditions
- Craving, Mastication Disorder, Memory Disorders, Executive Dysfunction
- Trial name
- NCT05046145
- Testing
- speech therapy for chewing + real tDCS
- Where
- Brazil
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Piauí
Neoplasms, Antioxidants
Oxidoreductive Balance and Lysosomal Activity in Cancer Patients.
The research aims to determine the parameters of oxidative stress and inflammatory processes and compare these parameters with the image obtained using positron emission tomography (PET) with 2-deoxy-2-[fluorine-18]fluoro…
- Conditions
- Neoplasms, Antioxidants, Oxidative Stress, Lipid Peroxidation
- Trial name
- NCT03470857
- Testing
- Patients
- Where
- 3 sites in Poland
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Nicolaus Copernicus University