Clinical trials: Oxidative Stress, completed
Healthy Adult Participants
Urban Exposome and Biological Age
The goal of this observational study is to evaluate the impact of the urban exposome, including air pollution and lifestyle-related stressors, on biological aging, inflammatory pathways, oxidative stress, and DNA methylation…
- Trial name
- IDEA (NCT07817836)
- Where
- Italy
- Volunteers
- 151 people
- Sponsor
- University of Pavia
Adrenal Insufficiency, Critical Illness
Pilot Study Assessing Oxidative Stress in Children
Role fo oxidative stress in adrenal insufficiency has not been studied. The degree of oxidative stress and it's role in pediatric critical illness is unknown.
- Trial name
- OxStress (NCT01052207)
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- Emory University
Diabetes Type 2
Oxidative and Antioxidant Indices to HIIT and Aloe Vera Supplementation in Patients With T2DM
Diabetes is a prevalent metabolic disease that leads to increased blood sugar levels due to insulin shortage or resistance. Type 2 diabetes is often linked to obesity, which can increase insulin resistance.
- Trial name
- NCT06377657
- Testing
- Exercise, Aloe vera
- Where
- Iran
- Volunteers
- 44 people
- Sponsor
- University of Nis
Craving, Mastication Disorder
Effects of Non-invasive Neuromodulation on Food Desire, Chewing Pattern, Executive Functions and Oxidative Stress.
From the change in self-regulation, memory is inhibited, allowing individuals to suppress or ignore unwanted or outdated associations and thus help to filter information relevant to dietary goals from irrelevant information.
- Conditions
- Craving, Mastication Disorder, Memory Disorders, Executive Dysfunction
- Trial name
- NCT05046145
- Testing
- speech therapy for chewing + real tDCS
- Where
- Brazil
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Piauí
Obesity
Spirulina Platensis Supplementation and Calorie Restriction in Obese Men : A Randomized Controlled Trial Protocol Study
The goal of this clinical trial is to evaluate the effects of spirulina platensis supplementation and calorie restriction on anthropometric parameters, body composition, lipid profile, insulin resistance, serum superoxide…
- Trial name
- NCT06076161
- Testing
- Spirulina supplementation and calorie restriction in obese men
- Where
- Indonesia
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Universitas Diponegoro
Chronic Obstructive Pulmonary Disease
The Anti-oxidant Effects of N-Acetylcysteine in Chronic Obstructive Pulmonary Disease (COPD)
Chronic obstructive pulmonary disease (COPD) is a condition defined as a disease state characterized by airflow limitation that is not fully reversible.
- Trial name
- NCT03956888
- Testing
- N-acetylcysteine
- Where
- Thailand
- Volunteers
- 35 people
- Sponsor
- Siriraj Hospital
Exercise-induced Inflammation
Effect of 4 Weeks Fish Oil Supplementation on Cycling Performance in Healthy Male Cyclists
Research Plan Eleven trained cyclists have completed 4 cycling performance trials, before and after 4 weeks of fish oil supplementation and before and after 4 weeks of placebo with a 4 week washout between supplementation…
- Trial name
- NCT03205241
- Testing
- n-3 PUFA
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Vivax Malaria, G6PD Deficiency
Safety and Efficacy of Different Regimens of Primaquine on Vivax Malaria Treatment in G6PD Deficient Patients
A clinical study to assess the safety and efficacy of alternative regimens of primaquine for radical cure of vivax malaria in glucose 6-phosphate dehydrogenase (G6PD) deficient. G6PD deficient patients with P.
- Trial name
- NCT03529396
- Testing
- Chloroquine, Primaquine
- Where
- 2 sites in Brazil
- Volunteers
- 106 people
- Sponsor
- Fundação de Medicina Tropical Dr. Heitor Vieira Dourado
Vitamin C Deficiency, Smoking
The Effect of Vitamin C on Wound Healing In Mandibular Fracture Patients
The goal of this study is to perform a randomized clinical trial to assess the effects of vitamin C versus placebo on wound healing in mandibular fracture patients.
- Conditions
- Vitamin C Deficiency, Smoking, Surgery, Surgery--Complications
- Trial name
- NCT03938584
- Testing
- Vitamin C
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Hennepin Healthcare Research Institute
Diabetic Neuropathies
Role of Carnosine in Combination With Vitamin B Complex in Preventing the Progression of Diabetic Neuropathy in Type 2 Diabetes Patients
Evaluation of the influence of oral administration of carnosine in combination with vitamin B Complex in preventing the progression of diabetic neuropathy in type 2 diabetes patients.
- Trial name
- NCT05422352
- Testing
- Carnosine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Beni-Suef University
Intra Operative Bleeding, Blood Salvage
Exposure of Salvaged Blood to Inflammation and Oxidative Stress: the Effect of Different Anticoagulant Regimes (HECICS)
The primary aim of this randomized controlled study is to determine whether the use Anticoagulant Citrate Dextrose Solution--Formula A (ACD-A) in cell salvage reduces inflammation and oxidative stress in cell saver blood compared…
- Trial name
- HECICS (NCT02674906)
- Testing
- ACD-A, Heparin
- Where
- Belgium
- Volunteers
- 75 people
- Sponsor
- Ziekenhuis Oost-Limburg
Non-Alcoholic Fatty Liver Disease
Biological Adaptations of Strength Training.
A two-trial repeated measures design will be employed in this investigation. Both the control trial and the exercise trial will last for 3 months.
- Trial name
- NCT04098484
- Testing
- Control Trial, Exercise Trial
- Where
- Greece
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Democritus University of Thrace
Preeclampsia, Pregnancy Loss
Early Pregnancy Antioxidant Supplementation in the Prevention of Preeclampsia
Use of Juice Plus+ food supplements, when initiated in the first trimester and used continuously thereafter, will result in a lower incidence of preeclampsia and pregnancy complications.
- Trial name
- NCT00583635
- Where
- United States
- Volunteers
- 684 people
- Sponsor
- University of Mississippi Medical Center
Peri-Implantitis, Bone Loss in Jaw
An Evaluation of Salivary Oxidant and Antioxidant Levels in Peri-implant Health and Disease
Objectives: Inflammatory lesions develop in the tissues surrounding implants are referred to as peri-implant diseases. Oxidants, play a role in inflammatory lesions.
- Conditions
- Peri-Implantitis, Bone Loss in Jaw, Dental Implant Failed, Dental Implant Failure Nos
- Trial name
- NCT05724706
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Biruni University
Loss of Solute Clearance
Effect of Replacement Volume of Haemodiafiltration and AST-120 on Toxins, Oxidative Stress and MicroInflammation
Accumulating evidence suggested that increased oxidative stress (OxSt) as well as inflammation are risk factors for cardiovascular events in hemodialysis patients.
- Trial name
- NCT01458652
- Testing
- Kremezin
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Tungs' Taichung Metroharbour Hospital
Endotoxemia, Inflammation
The Effects of Atazanavir-induced Hyperbilirubinemia During Human Endotoxemia
Excessive inflammation, production of free radicals and vascular injury are considered the main contributors to the development of organ dysfunction in patients with severe infections and sepsis.
- Conditions
- Endotoxemia, Inflammation, Multi Organ Dysfunction Syndrome, Sepsis
- Trial name
- NCT00916448
- Testing
- Atazanavir, E. coli endotoxin
- Where
- Netherlands
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Postoperative Pain, Oxidative Stress Response
Analgesic and Antioxidant Effects of Melatonin in Pediatric Surgery
Background. Long-term consequences of postoperative pain are detrimental in children. We tested the hypothesis that melatonin reduces postoperative pain and oxidative stress involving sirtuin pathway in children undergoing…
- Trial name
- NCT06724432
- Testing
- oral melatonin
- Where
- 2 sites in Italy
- Volunteers
- 44 people
- Sponsor
- University of Parma
Hypertension
Effect of Blood Donation on Blood Pressure, Iron Metabolism, Oxidative Stress
The investigators want to investigate the effects of blood donation to blood pressure, to iron metabolism and oxidative stress. There are results of other studies that show, that there is a positive effect of blood donation to…
- Trial name
- NCT01553409
- Where
- Germany
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Obesity Adult Onset
Gut Microbiota, Mitochondrial Function and Metabolic Health in Obesity
It has been suggested that individuals with the condition known as metabolically healthy obesity (MHO) may not have the same increased risk of developing metabolic abnormalities as their non-metabolically healthy counterparts.
- Trial name
- NCT06279780
- Testing
- very low-calorie diet
- Where
- Spain
- Volunteers
- 109 people
- Sponsor
- Celia Bañuls
Cardiac Arrest
Vitamin C in Post-cardiac Arrest
Only half of the patients suffering from cardiac arrest arrive at the hospital alive. Of these survivors, more than 50% will still die or remain severely disabled.
- Trial name
- VITaCCA (NCT03509662)
- Testing
- Vitamin C, Thiamine
- Where
- Netherlands
- Volunteers
- 270 people
- Sponsor
- Amsterdam UMC, location VUmc
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