Clinical trials: Oxycontin
Labor Pain
Oxycodone for Labor Pain - Pharmacokinetics (PK), Safety and Efficacy
Childbirth is one of the most painful events that a woman is likely to experience, and thus is a major concern for most parturient.
- Trial name
- Oksiobs (NCT01016821)
- Testing
- Oxycodone
- Where
- Finland
- Volunteers
- 15 people
- Sponsor
- Kuopio University Hospital
Postoperative Nausea, Adverse Effects
Safety and Tolerability of Controlled-release Oxycodone on Postoperative Pain in Oncologic Head and Neck Surgery
The hypothesis of this study is that controlled release oxycodone can be safe and well tolerated for the control of postoperative pain in surgery for head and neck cancer.
- Conditions
- Postoperative Nausea, Adverse Effects, Opioid Analgesic Adverse Reaction, Pain
- Trial name
- NCT01834898
- Testing
- Controlled-release oxycodone
- Where
- Brazil
- Volunteers
- 83 people
- Sponsor
- Instituto Nacional de Cancer, Brazil
Pain
Evaluate The Pharmacokinetics and Safety Of Oxycodone Oral Solution In Pediatric and Adolescent Subjects
The objective of this study is to characterize the pharmacokinetics and to evaluate the safety of single and multiple doses of Oxycodone Oral Solution in pediatric and adolescent subjects for postoperative pain.
- Trial name
- NCT01959204
- Testing
- Oxycodone
- Where
- 9 sites in United States
- Volunteers
- 97 people
- Sponsor
- VistaPharm, Inc.
Healthy
A Study to Determine the Fasting Bioequivalence of Reformulated OXY Tablets Manufactured at Two Different Facilities
The purpose of this study is to assess the bioequivalence of a new oxycodone formulation (10 mg) manufactured at the Totowa, NJ facility relative to the formulation (10 mg) manufactured at the Wilson, NC facility in the fasted…
- Trial name
- NCT01101308
- Testing
- Reformulated OXY (Totowa) (oxycodone HCl), Reformulated OXY (Wilson) (oxycodone HCl)
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Purdue Pharma LP
Surgery
Oxycodone Extended-release in the Treatment of Perioperative Pain in Patients Undergoing Orthopaedic Surgery
Inadequate control of acute postoperative pain (DAPO) brings deleterious consequences for the patient, including significant cardiovascular and respiratory complications. Apart from the human suffering that is undeniable pain.
- Trial name
- NCT02238340
- Testing
- Extended-release oxycodone, Extended- release Oxycodone, ketoprofen
- Where
- Venezuela
- Volunteers
- 40 people
- Sponsor
- Hospital Central Dr. Luis Ortega
Post Operative Pain
An Open Label, Prospective Study of the Analgesic Efficacy of Oral Xartemis Compared to Generic Oxycodone/APAP( Acetaminophen) in the Treatment of Moderate to Severe Post Operative Pain.
The purpose of this study is to compare the analgesic efficacy of Xartemis 15mg/650mg by mouth every 12 hours for the management of acute moderate to severe post operative pain to generic Oxycodone/APAP(acetaminophen) (Percocet)…
- Trial name
- NCT02101476
- Testing
- Percocet, Xartemis
- Where
- United States
- Volunteers
- 114 people
- Sponsor
- Lotus Clinical Research, LLC
Sleep Apnea
Impact of Tramadol and Oxycodone on Sleep Apnea
Postoperative pain is usually treated with opioids. Among them, oxycodone is popular in the daily practice as it is administered orally and is easily titrated.
- Trial name
- TROXAT (NCT03454217)
- Testing
- Oxycodone, Tramadol
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Hyperalgesia, Opioid-Related Disorders
Dextromethorphan, Gabapentin, and Oxycodone to Treat Opioid-Induced Hyperalgesia
Individuals who reduce or stop use of opioid medications are at risk for developing hyperalgesia, which is an increased sensitivity to pain.
- Trial name
- NCT00218374
- Testing
- Gabapentin
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Pain, Chronic Back Pain
An Open-label Evaluation of Tapentadol Extended Release (ER) in Participants With Moderate to Severe Chronic Pain After Conversion From Hydrocodone, Oxycodone Controlled Release (CR), and/or Morphine Sustained Release (SR)
The purpose of this study is to evaluate tapentadol Extended Release (ER) in the treatment of moderate to severe chronic pain in participants with a diagnosis of chronic low back pain (LBP) or osteoarthritis (OA) of the hip or…
- Conditions
- Pain, Chronic Back Pain, Chronic Low Back Pain, Osteoarthritis Pain In The Hip or Knee
- Trial name
- NCT01631513
- Testing
- Nucynta ER
- Where
- 7 sites in United States
- Sponsor
- Janssen Scientific Affairs, LLC
Pain, Postoperative, Medication Adherence
Pain Medication After Ambulatory Surgery
In Finland, there are no guidelines concerning post-operative pain medication of ambulatory surgery patients. There is a wide variety in drug prescription and medication practices of various doctors and clinics.
- Conditions
- Pain, Postoperative, Medication Adherence, Adverse Drug Event
- Trial name
- NCT03135470
- Where
- Finland
- Volunteers
- 146 people
- Sponsor
- Helsinki University Central Hospital
Pain
Single Dose Pharmacokinetics of Egalet® Oxycodone
The purpose of the study is to evaluate the pharmacokinetic profile of different Egalet® oxycodone formulations and compare to a marketed oxycodone product.
- Trial name
- NCT00801788
- Testing
- Oxycodone hydrochloride
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Egalet Ltd
Pain
Pharmacokinetic (PK) Study of OxyNorm Injections in Chinese Patient
This is a single center, open label, randomized, parallel group single dose intravenous (i.v.) administration study. The subjects will be randomized to receive a single dose of OxyNorm® 2.5, 5, and 10mg.
- Trial name
- NCT01482936
- Testing
- Oxycodone (OxyNorm®) Injection
- Where
- China
- Volunteers
- 44 people
- Sponsor
- Mundipharma (China) Pharmaceutical Co. Ltd
Pain, Back Pain
NUCYNTA (Tapentadol Immediate Release) Versus Oxycodone Immediate Release in the Treatment of Acute Low Back Pain
Evaluate how NUCYNTA (tapentadol) immediate release (IR) compares with oxycodone IR in the treatment of acute low back pain.
- Conditions
- Pain, Back Pain, Low Back Pain, Back Pain With Radiation
- Trial name
- NCT00986180
- Testing
- NUCYNTA, Oxycodone IR
- Where
- 74 sites in United States
- Volunteers
- 667 people
- Sponsor
- Ortho-McNeil Janssen Scientific Affairs, LLC
Opioid Use Disorder
NT-814: Evaluation of Its Ability to Alter the Abuse Liability of Oxycodone in an Exploratory Clinical Study
Healthy adult men who abuse opioids and are physically dependent on them will be invited to participate in a study to examine the ability of NT-814, a neurokinin (NK) antagonist at the 1 and 3 receptor subtypes, to alter the…
- Trial name
- NT-814 (NCT02692157)
- Testing
- NT-814 50 mg, NT-814 100 mg, NT-814 200 mg
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Analgesic Adverse Reaction, Cesarean Delivery Affecting Newborn
Oxycodone in Serum After Postoperative Oral Oxycodone in Caesarean Sections Under Spinal Anesthesia
All patients undergoing an elective caesarean section under spinal anesthesia will, according to the hospital routines, receive 10 mg oxycodone slow-release tablet when arriving at our postoperative care unit (PACU).
- Trial name
- NCT02717637
- Where
- Norway
- Volunteers
- 50 people
- Sponsor
- University Hospital, Akershus
Healthy Volunteers
A Study to Determine the Fed Bioequivalence of Reformulated OXY Tablets and Original OxyContin® (OXY) Tablets
To assess the bioequivalence of reformulated OXY tablets (40 mg) relative to the original OxyContin® (OXY) formulation (40 mg) in the fed state.
- Trial name
- NCT01100320
- Testing
- Reformulated OXY (oxycodone HCl), Original OxyContin® (OXY) (oxycodone HCl)
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Purdue Pharma LP
Total Laparoscopic Hysterectomy
Clinical Study of Equivalent Doses of Oxycodone or Tegileridine on Patients Undergoing Gynecological Laparoscopic Hysterectomy
This randomized, double-blind, controlled study aims to evaluate the efficacy and safety of Tegileridine or Oxycodone for postoperative analgesia in patients undergoing Total Laparoscopic Hysterectomy（TLH）.
- Trial name
- NCT07326683
- Testing
- Tegileridine (tegileridine fumarate injection, IV), Oxycodone（Oxycodone Hydrochloride Injection，IV）
- Where
- China
- Volunteers
- 68 people
- Sponsor
- Xin Chen
Epidural, Oxycodone
Epidural Oxycodone for Pain Management for Lower Limb Amputation
The aim of this study is to evaluate the effect of epidural oxycodone for pain management after lower limb amputation.
- Conditions
- Epidural, Oxycodone, Pain, Lower Limb Amputation
- Trial name
- NCT06276179
- Testing
- Oxycodone, Bupivacaine
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Kafrelsheikh University
Disorder of Knee
Open-Label Study of Oxycodone/APAP to Treat Post-Operative Pain Following Arthroscopic Knee Surgery
This is a pilot trial using this product in patients for the management of pain after outpatient arthroscopic knee surgery. This is an open-label study and the two active ingredients are well known pharmacologic entities.
- Trial name
- NCT02391844
- Testing
- Oxycodone
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- International Clinical Research Institute
Burns
Oxycodone (10, 20 mg) in a Postoperative Dressing
The study mainly focuses on pain management using 10- or 20mg oxycodone burn wound dressing at Poznan University of Medical Sciences.
- Trial name
- NCT06142591
- Testing
- Oxycodone 10mg, Oxycodone 20mg
- Volunteers
- 20 people
- Sponsor
- Poznan University of Medical Sciences