Clinical trials: Oxygen
Left Ventricular Failure, Unspecified
Daily Life Activities in Patients Treated With Continuous-Flow Left Ventricular Assist Devices
Investigation of oxygen uptake during daily life activities in HF patients with and without LVADs.
- Trial name
- Act-VAD (NCT04732039)
- Testing
- Measurement of peak oxygen uptake
- Where
- Denmark
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Anesthesia, Airway Morbidity
Preoxygenation Using High Flow Oxygen : Efficacy and Tolerance in Healthy Volunteers
High flow nasal cannula oxygen has been proposed to perform preoxygenation in patients with acute respiratory failure requiring orotracheal intubation in intensive care units.
- Conditions
- Anesthesia, Airway Morbidity, Safety Issues
- Trial name
- PreOx-OHD (NCT03399695)
- Testing
- preoxygenation
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Physical Inactivity, Oxygen Consumption
Gentle Jogger and Oxygen Consumption
This is a non randomized study to determine the effects of Gentle Jogger(GJ), a passive jogging device on oxygen consumption in 2 postures supine and seated.
- Trial name
- NCT03602365
- Testing
- Gentle Jogger (GJ)
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Sackner Wellness Products LLC
Spinal Cord Injuries
Hyperbaric Oxygen and Orthopedic Comprehensive Treatment for Traumatic Incomplete Spinal Cord Injury in the Plateau
To observe modified Barthel index, American Spinal Injury Association (ASIA) impairment scale grading, sensory score and motor score in patients with incomplete SCI in the plateau using 0.2 MPa HBO combined with pedicle screw…
- Trial name
- NCT03112941
- Testing
- control group, hyperbaric oxygen group
- Volunteers
- 164 people
- Sponsor
- Qinghai University
Anterior STEMI
The RECOVERY Study: Using Supersaturated Oxygen Therapy To Treat Small Vessel Blockages After a Heart Attack
The study tests whether adding supersaturated oxygen (SSO₂) therapy to standard stent treatment can improve heart recovery after a major heart attack (anterior STEMI).
- Trial name
- NCT07000266
- Testing
- Percutaneous Coronary Intervention (PCI), Diagnostic Imaging, Device Treatment
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Fundacio Privada Mon Clinic Barcelona
Healthy, Normoxia
Measurement of Retinal Blood Flow, Retinal Oxygenation and Retinal Oxygen Extraction in Healthy Subjects During Normoxia and Systemic Hyperoxia
The inner retina is crucially dependent on an adequate retinal blood supply. When the retina becomes ischemic and hypoxic this results in severe vision loss due to retinal neovascularization.
- Conditions
- Healthy, Normoxia, Systemic Hypoxia
- Trial name
- NCT00914407
- Testing
- Oxygen
- Where
- Austria
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Pulmonary Diseases, Oxygen Therapy
Effects of High-Flow Nasal Cannula on Exercise Outcomes in Lung Transplant Candidates: A Pilot Study
The study evaluated patients on the national lung transplant waiting list. It was pioneering in assessing high-complexity patients with severe pulmonary diseases subjected to a cardiopulmonary rehabilitation protocol using a…
- Conditions
- Pulmonary Diseases, Oxygen Therapy, High-flow Nasal Cannula, Exercise Tolerance
- Trial name
- NCT06620081
- Testing
- Performance Tests, Functional Tests
- Where
- Brazil
- Volunteers
- 10 people
- Sponsor
- Hospital Israelita Albert Einstein
Stroke
Correlating Brain Tissue Oxygen and Regional Cerebral Oximetry
Controversy surrounds the use of regional cerebral oximetry (rSO2) as a measure of true cerebral oxygenation because of extracranial signal contamination and unmeasured confounding of cerebral a:v ratio.
- Trial name
- NCT03128957
- Testing
- IVOS cerebral oximeter, Licox cerebral oxygenation monitor, Cerebral oxygenation
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Michigan
Exposure to Man-made Visible Light
Systematically Assessing Effects of Colored Light on Humans With a Multi-modal Approach (Substudy 7 of 7)
NOTE: This is the seventh of in total 7 sub-studies related to the Ethics Committee of the Canton of Bern Ref. No. KEK-BE 2016-00674.
- Trial name
- NCT02919137
- Testing
- Visible light exposure
- Where
- Switzerland
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Bern
Rapid Sequence Intubation
Pre-oxygenation With Real Time End-tidal Oxygen Measurements Versus Single Breath Measurements
This study examines the performance of a nasal cannula end-tidal oxygen (EtO2) measurement as compared to the gold standard of single breath end-tidal oxygen measurements in healthy volunteers.
- Trial name
- NCT03840486
- Testing
- Non-rebreather mask (NRBM), Non-invasive ventilator mask (NIV), Nasal cannula EtO2 sensor
- Where
- 2 sites in United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Emory University
Interstitial Lung Disease
Ambulatory Oxygen for ILD
People with interstitial lung disease (ILD) are frequently prescribed ambulatory oxygen, to increase oxygen levels in the blood during daily activities. The best way of delivering this type of oxygen has not been established.
- Trial name
- NCT01906931
- Testing
- Portable oxygen concentrator, Portable oxygen cylinder
- Where
- Australia
- Volunteers
- 10 people
- Sponsor
- Anne Holland
Brain Neoplasms
Radiotherapy - Cerebrovascular Reactivity (RT-CVR Study)
Brain tumours often have low oxygen levels, and that makes them more resistant to radiation therapy. If patients breathe the right mixture of oxygen during treatment, radiation may work better.
- Trial name
- NCT00297024
- Testing
- MRI
- Where
- Canada
- Volunteers
- 14 people
- Sponsor
- University Health Network, Toronto
Skin Ulcer
The Regeneration Effects of Derma-PACE Shockwave in Chronic Diabetic Ulcers
Management of chronic diabetic foot skin ulcers require multidisciplinary approaches including diabetic control, wound care, antibiotic, shoe wear off-loading, and surgery in selected cases.
- Trial name
- NCT01219127
- Testing
- Derma-PACE
- Volunteers
- 100 people
- Sponsor
- Chang Gung Memorial Hospital
Breast Cancer, Lymphedema
Hyperbaric Oxygen Therapy Compared With Standard Therapy in Treating Chronic Arm Lymphedema in Patients Who Have Undergone Radiation Therapy for Cancer
RATIONALE: Hyperbaric oxygen therapy may be effective in repairing damaged tissue and reducing lymphedema caused by radiation therapy for cancer.
- Conditions
- Breast Cancer, Lymphedema, Perioperative/Postoperative Complications, Radiation Fibrosis
- Trial name
- NCT00077090
- Testing
- hyperbaric oxygen
- Where
- 5 sites in United Kingdom
- Volunteers
- 63 people
- Sponsor
- Institute of Cancer Research, United Kingdom
Colorectal Cancer
RADOX' Reduced Abdominal Distension and Oxygen Delivery
The use of laparoscopic surgery is continuing to increase in colorectal resection and expected reach 80% in the next 10 years. Although laparoscopic (keyhole) or minimally invasive surgery can lead to faster recovery it can also…
- Trial name
- RADOX (NCT02045680)
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Dr Michael Scott
Anemia, Critical Illness
Oxygen Extraction-guided Transfusion in Critically Ill Patients
Anemia is common in intensive care unit (ICU) patients and often appears early in the ICU course. The optimal management red blood cells RBC transfusion in critically ill patients remains controversial and clinical studies in…
- Trial name
- NCT03767127
- Where
- Italy
- Volunteers
- 177 people
- Sponsor
- Università degli Studi di Ferrara
Intensive Care Unit, Mechanical Ventilation
Night-time Dexmedetomidine-esketamine Infusion and Sleep Quality in ICU Patients
Dexmedetomidine and ketamine are both suggested for sedation and analgesia in ICU patients. Recent studies suggest that low-dose dexmedetomidine or ketamine/esketamine may improve sleep quality of ICU patients.
- Conditions
- Intensive Care Unit, Mechanical Ventilation, Dexmedetomidine, Esketamine
- Trial name
- NCT05718024
- Testing
- Dexmedetomidine-esketamine, Routine sedation and analgesia
- Where
- China
- Volunteers
- 174 people
- Sponsor
- Peking University First Hospital
Exposure to Man-made Visible Light
Systematically Assessing Effects of Colored Light on Humans With a Multi-modal Approach (Substudy 5 of 7)
NOTE: This is the fifth of in total 7 sub-studies related to the Ethics Committee of the Canton of Bern Ref. No. KEK-BE 2016-00674.
- Trial name
- NCT02919189
- Testing
- Visible light exposure
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Bern
30% Oxygen Concentration During Colorectal Surgery, 80% Oxygen Concentration During Colorectal Surgery
Supplemental Oxygen in Colorectal Surgery: A Quality Improvement Project
Our primary objective is to develop a clinical pathway for care of patients having colorectal surgery at the Clinic. In particular, the investigators would like to determine what intraoperative concentration of oxygen is optimal…
- Trial name
- NCT01777568
- Testing
- 30% oxygen, 80% oxygen
- Where
- United States
- Volunteers
- 5,749 people
- Sponsor
- The Cleveland Clinic
Pediatric Sedation
Evaluation of the Efficacy of Oxygen Therapy and Clinical Feasibility of High Flow Nasal Cannula During Moderate and Deep Sedation in Pediatric Patients
The investigators evaluate the efficacy and safety of routine administration of oxygen during moderate or deep sedation in pediatric patients.
- Trial name
- NCT04852432
- Testing
- high flow nasal cannula, nasal prong
- Where
- South Korea
- Volunteers
- 258 people
- Sponsor
- Seoul National University Hospital