Clinical trials: Oxygen Consumption
Heart Failure, Systolic, Ketonemia
Ketones in Heart Failure - Effects on Cardiac Efficiency
Ketones may have beneficial effects on myocardial metabolism and hemodynamics. In the present study, healthy test subjects and patients with heart failure with reduced ejections fraction will be investigated in a randomized…
- Trial name
- NCT03073356
- Testing
- Infusion of 3-OHB
- Where
- Denmark
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Healthy
Oxygen Uptake Kinetics During Recovery From Maximal and Submaximal Exercise
Measurements of dynamic changes in oxygen uptake (VO2 kinetics) during recovery from exercise may describe regulatory control of oxygen transport and utilization and have greater reliability and less inherent risk than assessment…
- Trial name
- NCT00001519
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Pulmonary Arterial Hypertension
The Combination Ambrisentan Plus Spironolactone in Pulmonary Arterial Hypertension Study
The purpose of this study is to find out if spironolactone added to ambrisentan for Pulmonary Arterial Hypertension (PAH) will increase exercise capacity.
- Trial name
- NCT02253394
- Testing
- Ambrisentan plus Spironolactone
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Brigham and Women's Hospital
Healthy
The Effects of Lower Extremity Blood Flow Restriction Training on Power, and Muscle Size.
Blood-flow restriction training (BFR) is a technique utilized to provide the benefits of high intensity exercise (strength, power, hypertrophy) when applied to exercise intensities that are insufficient to produce these benefits…
- Trial name
- NCT03983070
- Testing
- Seated Rowing Ergometer, Deadlift, Blood flow restriction
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Campbell University, Incorporated
Sarcopenia, Old Age; Atrophy
Beetroot Juice Resistance Training Older Adults
The present study compared the effects of a nitrate containing beetroot juice supplement (BRJ+Nitrate) vs. a placebo (Control) on total and regional fat free mass, quadriceps muscle strength, lower body mobility, and VO2peak in…
- Trial name
- NCT05460351
- Testing
- BRJ+Nitrate, Control
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Wake Forest University
Chronic Obstructive Pulmonary Disease
Effect of Supplemental Oxygen on Maximal Oxygen Consumption in Patients With Chronic Obstructive Pulmonary Disease
Maximal consumption of oxygen (VO2max) during exercise is used in patients with chronic obstructive pulmonary disease (COPD) to stratify perioperative risk.
- Trial name
- NCT01294033
- Testing
- Fractional inspired oxygen (FiO2) 0.21, Fractional inspired oxygen 0.28
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Coronary Artery Bypass Surgery
Exercise Training in Patients After Bypass Surgery
Based on clinical experience both physical condition and psychological recovery after surgery are individually variable. Exercise training plays an important part, has been recommended for CABS patients in order to enhance…
- Trial name
- NCT05188352
- Testing
- Chest physiotherapy, Aerobic exercise training
- Volunteers
- 30 people
- Sponsor
- Bezmialem Vakif University
Diabetic Macular Edema
Change Oxygen Consumption Following Intravitreal Treatment of Lucentis (Ranibizumab) in Eyes With Diabetic Macular Edema
Recent reports suggest that anti-VEGF agents (ranibizumab) may suppress the progression of retinal nonperfusion area. This protective effect would cause the increase of the oxygen consumption in the diabetic retina.
- Trial name
- NCT02329132
- Testing
- Ranibizumab
- Where
- Japan
- Volunteers
- 30 people
- Sponsor
- Kagawa University
Diabetic Ketoacidosis
Thiamine as Adjunctive Therapy for Diabetic Ketoacidosis
This is a randomized, double-blind, placebo-controlled trial to determine if administration of intravenous thiamine will lead to quicker resolution of acidosis in patients admitted to the hospital with diabetic ketoacidosis.
- Trial name
- NCT03717896
- Testing
- 200mg IV thiamine in 50mL 0.9% saline
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- Beth Israel Deaconess Medical Center
COVID-19, Endothelial Function
Diagnostics of Coronavirus Disease 2019 Cardiovascular Complications
Aim of this prospective, observational, multi-centered, randomized study is to detect cardiovascular complications in patients after coronavirus infection.
- Conditions
- COVID-19, Endothelial Function, Diastolic Dysfunction, Oxygen Consumption
- Trial name
- NCT05608603
- Testing
- Portable cardiac monitor "CardioQvark", Cardiorespiratory stress test, Analysis of exhaled air using the Compact PTR-MS proton mass spectrometer
- Where
- Russia
- Volunteers
- 100 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Oxidative Stress, Aging
Stress Resilience Study
The purpose of this study is to test the hypothesis that physiological adaptations to regular exercise training (i.e. physical fitness) attenuates age-related decline in stress resilience to both oxidative stress and the…
- Trial name
- NCT00891488
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Kronos Longevity Research Institute
Overweight and Obesity
Biking vs. Running: Comparison of EPOC, Substrate Oxidation, Appetite and Energy Intakes in Men With Overweight/Obesity.
The management of obesity involves hygienic and dietary measures that include appropriate nutrition and an increase in physical activity (PA).
- Trial name
- BIKERUN (NCT06082310)
- Testing
- Exercise
- Where
- France
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Laboratoire des Adaptations Métaboliques à l'Exercice en conditions Physiologiques et Pathologiques
Health Behavior
Leggings With Resistance Bands on Caloric Expenditure During Exercise
The primary aim of this study is to investigate the impact of incorporating shortened resistance bands (SRB) into leggings on cardiovascular responses and caloric expenditure during exercise in young, healthy women.
- Trial name
- NCT06547060
- Testing
- Exercise leggings
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Schizophrenia, Schizotypal Disorder
Feasibility and Relevance of High-Intensity Functional Training in Patients With First-Episode Psychosis
The aim of the COPUS study is to investigate, whether it is possible to recruit and retain young people with first-episode psychosis, to an 8 week supervised High-Intensity Functional Training intervention (HIFT) (i.e.
- Conditions
- Schizophrenia, Schizotypal Disorder, First Episode Psychosis, Psychotic Disorders
- Trial name
- COPUS (NCT03409393)
- Testing
- The COPUS intervention, Usual Care (OPUS treatment)
- Where
- Denmark
- Volunteers
- 27 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
ACL Injury, Hemodynamics
A Paradigm Shift in Musculoskeletal Rehabilitation Assessment After ACL Reconstruction Using Near-Infrared Spectroscopy
This study aims to establish and compare muscle haemodynamic response patterns in physically active subjects with anterior cruciate ligament (ACL) reconstruction, at different time points after surgery, against healthy controls…
- Conditions
- ACL Injury, Hemodynamics, Oxygen Consumption Based Assessment of Hemodynamics, Exercise
- Trial name
- HemoNIRS-LCA (NCT06621355)
- Testing
- Incremental Interval Test on a Cycle Ergometer
- Where
- Spain
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Universitat de Lleida
High Intensity Interval Training (Cycling), High Intensity Interval Training (Running)
Acute Effects of High-intensity Interval Aerobic and Functional Training at Different Intensities
Moderate-intensity physical exercise is widely recognized for its health benefits, yet time constraints limit adherence. High-intensity interval training (HIIT) has gained popularity as a more time-efficient alternative…
- Conditions
- High Intensity Interval Training (Cycling), High Intensity Interval Training (Running), High Intensity Functional Training, Moderate Intensity Functional Training
- Trial name
- HIIT-HIFT-FT (NCT07180550)
- Testing
- High-intensity interval training, running, High-intensity interval training, cycling, High-intensity functional training
- Where
- Spain
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- European University Miguel de Cervantes
Hyperbaric Oxygenation, Cardiorespiratory Fitness
Retrospective Analysis of CPET and Cognitive Tests of Healthy Individuals, Treated With 60 Treatment of HBOT
This retrospective observational study evaluates physiological and cognitive changes following a series of 60 hyperbaric oxygen therapy (HBOT) sessions in healthy individuals.
- Conditions
- Hyperbaric Oxygenation, Cardiorespiratory Fitness, Cognition
- Trial name
- HBOT (NCT07596641)
- Testing
- Hyperbaric Oxygen Therapy - HBOT
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Healthy
Development of an Exoskeleton for Patients' Mobility.
The goal of this clinical trial is to investigate the performance of a state-of-the-art adaptive CPG-based exoskeleton control system (intelligent mode) under a multi-metric analysis (involving three-dimensional gait analysis…
- Trial name
- NCT06513390
- Testing
- Exoskeleton of default mode, Exoskeleton of Intelligent mode
- Where
- Thailand
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Vidyasirimedhi Institute of Science & Technology (VISTEC)
Microvascular Disease, Microvascular Complications
Comparison of Differencens in VO2-max, Perfusion of the Heart and Brain and Cognitive Performance Between Patients with Type 2 Diabetes and Healthy Age Matched Controls.
In the aging population, ischemic heart disease, stroke and dementia are increasingly prevalent. Diagnosis and treatment of the former two i.e., large-vessel coronary heart disease and endovascular thrombectomy of the brain in…
- Conditions
- Microvascular Disease, Microvascular Complications, Dementia, Diabetes Mellitus Type 2
- Trial name
- SVAT (NCT06628297)
- Testing
- PET
- Where
- Denmark
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University Hospital Bispebjerg and Frederiksberg
COVID-19
Investigation of the Muscle Oxygenation in Patients With Post COVID-19 Syndrome
More than 60% of patients infected with COVID-19 have long-term symptoms. These symptoms are associated with common ground-glass opacities on computed tomography scans and chest radiographs.
- Trial name
- NCT05957575
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people
- Sponsor
- Gazi University