Clinical trials: Oxygen Disorders
Ulcers
Effect of NIRS-assisted Assessment on Chronic Lower Extremity and Other Chronic Non-healing Ulcers
Investigation of the predictive value of Near Infrared Spectroscopy in Chronic Lower Extremity and Other Chronic non-healing Ulcers
- Trial name
- NCT06702852
- Testing
- NIRS imaging in addition to SOC
- Where
- 4 sites in United States
- Volunteers
- 221 people
- Sponsor
- Kent Imaging Inc
Therapy, Oxygen Inhalation
Effect of Halotherapy in Children With Asthma
Introduction: Asthma is a chronic respiratory disease that can affect all age groups and is characterized by episodic and reversible wheezing, shortness of breath, chest tightness and cough attacks.
- Trial name
- NCT06250452
- Testing
- Halotherapy (Salt Therapy)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Igdir University
Intracranial Neoplasm
Oxygen-Enhanced MRI for Generating Hypoxia Maps in Patients With Intracranial Tumors
This clinical trial evaluates the feasibility of performing oxygen-enhanced magnetic resonance imaging (MRI) to generate hypoxia maps in patients with intracranial tumors.
- Trial name
- NCT05904704
- Testing
- Magnetic Resonance Imaging, Oxygen Therapy
- Where
- United States
- Sponsor
- OHSU Knight Cancer Institute
Cerebral Small Vessel Diseases
Effect of Hyperbaric Oxygen on Functional Connectivity in Patients With Cerebral Small Vessel Disease
Patients will have a Functional MRI before and after 10 hyperbaric Oxygen treatments.
- Trial name
- NCT02890888
- Testing
- hyperbaric oxygen treatment
- Where
- 3 sites in United States
- Volunteers
- 6 people
- Sponsor
- St. Luke's Hospital, Chesterfield, Missouri
Critical Illness, Sepsis
Cerebral Oxygen Challenge of Passive Leg Raising Test in Sepsis
Sepsis related cerebral dysfunction was underestimated in critical illness setting, and inflammatory response of brain could not be monitored directly and cerebral oximetry offered information of cerebral dysfunction.
- Conditions
- Critical Illness, Sepsis, Cerebral Injury
- Trial name
- NCT03523169
- Volunteers
- 120 people
- Sponsor
- Peking Union Medical College Hospital
Nsclc, EGFR Activating Mutation
Pembrolizumab, Lenvatinib and Chemotherapy After TKIs in NSCLC
Adding chemotherapy or anti-VEGF to immunotherapy is an emerging strategy to enhance the efficacy of immunotherapy in many cancers.
- Conditions
- Nsclc, EGFR Activating Mutation, EGF-R Positive Non-Small Cell Lung Cancer, ALK Gene Rearrangement Positive
- Trial name
- NCT04989322
- Testing
- Pembrolizumab, Lenvatinib, Pemetrexed
- Where
- Hong Kong
- Volunteers
- 46 people
- Sponsor
- Dr Joanne CHIU
Cephalalgia
Protocol to Ease Acute Cephalalgia in Emergency-department
The purpose of this study is to determine if the use of a therapeutic and global protocol to relieve cephalalgia is helpful in the emergency department of Grenoble University Hospital.
- Trial name
- PEACE (NCT02236442)
- Testing
- Recommendation to use global headache treatment protocol
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Grenoble
Unrecognized Condition
Preoxygenation With Optiflow™ - the Effect of Speech on Lung Oxygenation.
If a patient speaks during the process of preoxygenation with high-flow nasal oxygen via the Optiflow™ system, is the efficacy reduced as measured by end-tidal lung oxygen content?
- Trial name
- NCT03766646
- Testing
- Optiflow
- Where
- United Kingdom
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Neuroendocrine Cell Hyperplasia of Infancy
Efficacy of Methylprednisolone Pulses in Neuroendocrine Celles Hyperplasia of Infancy : An Early Phase Study
Childhood interstitial lung diseases (chILD) are a heterogeneous group of rare and severe disorders with an estimated prevalence of 1/100,000.
- Trial name
- CORTICONEHI (NCT06471556)
- Testing
- IV Methylprednisolone pulses
- Where
- France
- Volunteers
- 18 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Overweight and Obese Adults, High Intensity Interval Exercise (HIIE)
Acute Effects of Isoenergetic HIIE vs. MICE on Key Parameters of Fat Mass Loss in Young Females With Overweight or Obesity
Overweight and obesity, particularly increased total and/or abdominal fat mass (FM), are strongly linked to the development of cardiovascular diseases.
- Trial name
- COMEFIT (NCT06868862)
- Testing
- Exercise
- Where
- Brazil
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Laboratoire des Adaptations Métaboliques à l'Exercice en conditions Physiologiques et Pathologiques
Periodontal Disease, Periodontal Diseases Inflammation
Comparative Evaluation of Oxygen-enriched and Chlorohexidine Mouthwashes as an Adjunct to Non-surgical Periodontal Therapy and Its Efficacy on Gingival Inflammation, Plaque Scores and Patient-reported Outcomes
comparison between CHX and oxygen-enriched mouthwash
- Conditions
- Periodontal Disease, Periodontal Diseases Inflammation, Gingivitis, Mouthwash
- Trial name
- NCT07861880
- Testing
- CHX mouthwash, Oxygen-enriched mouthwash
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Cairo University
Bronchiolitis
Safety Study of Home Oxygen Therapy for Children With Acute Bronchiolitis
Home oxygen therapy is considered an appropriate and relatively safe option for children with chronic respiratory problems such as chronic lung disease of prematurity, but the use of home oxygen therapy for children with acute…
- Trial name
- NCT00677066
- Testing
- Home oxygen therapy
- Where
- Australia
- Volunteers
- 44 people
- Sponsor
- Princess Margaret Hospital for Children
Obstructive Sleep Apnea
Is My Sleep Tracker Tracking my Sleep?
The purpose of this research study is to collect health and physiological data using commercially available wristband fitness tracker devices (FitBit and Garmin devices) to help determine their accuracy and reliability at…
- Trial name
- NCT06174558
- Testing
- Sleep Tracking Devices
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- Respiratory Specialists
Severe Mental Disorder
Digital Follow-up of Aerobic Interval Training in Outpatients With Mental Disorders
This randomized-controlled trial (RCT) will investigate if digital follow-up of exercise, i.e. followup through the new citizen portal HelsaMi, coupled with an exercise app can result in exercise adherence and improved oxygen…
- Trial name
- DIG-EX (NCT06628011)
- Testing
- Intervention group/training group
- Where
- Norway
- Volunteers
- 40 people
- Sponsor
- Norwegian University of Science and Technology
Critical Illness, Intensive Care Units
Characterising Changes in Muscle Quantity and Quality in Patients Requiring ECMO Oxygen During Critical Illness
This study will identify the changes in different muscles of patients receiving Extracorporeal Membrane Oxygenation (ECMO) during critical illness and admission to Intensive Care Unit (ICU).
- Conditions
- Critical Illness, Intensive Care Units, Extracorporeal Membrane Oxygenation
- Trial name
- ECMO USS (NCT02995811)
- Testing
- Observational Cohort
- Where
- United Kingdom
- Volunteers
- 21 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
COPD Method Evaluation, Chronic Obstructive Pulmonary Disease Method Evaluation
Evaluation of an Oxygen Enhanced Magnetic Resonance Imaging Method on Patients With Chronic Obstructive Pulmonary Disease During 8 Weeks Treatment With Either Symbicort Turbuhaler or Oxis Turbuhaler
The main purpose of this study is to evaluate the sensitivity of a new oxygen enhanced magnetic resonance imaging (OE-MRI) method in detecting changes in the lungs of patients with moderate to severe chronic obstructive pulmonary…
- Trial name
- NCT01257048
- Testing
- Formoterol Turbuhaler, Budesonide/Formoterol Turbuhaler
- Where
- 2 sites in Sweden, United Kingdom
- Volunteers
- 34 people
- Sponsor
- AstraZeneca
COVID-19
Passive Immunotherapy In Patients With SARS CoV-2
Plasma from convalescent individuals (convalescent plasma, CP) has been used for more than a hundred years for the treatment of infectious diseases.
- Trial name
- CoV-PlasGal (NCT05578391)
- Testing
- Convalescent plasma
- Where
- Spain
- Volunteers
- 61 people
- Sponsor
- Fundacin Biomedica Galicia Sur
Foot Ulcer, Diabetic
Continuous Diffusion of Oxygen (CDO) Treatment for Healing of Diabetic Foot Ulcers
This is a pilot study. Maximum 30 subjects with a diabetic foot ulcer (DFU) or surgical foot wound will be consented in order to have 20 eligible subjects who will be enrolled and completed the study.
- Trial name
- EO2 (NCT02501538)
- Testing
- Transcutaneous O2 device
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of Texas Southwestern Medical Center
Cystic Fibrosis
Effects of Training Intensity on Physical Fitness and Body Composition in Cystic Fibrosis
Aim of the randomized controlled trial is to investigate the effects of endurance training with different intensities on physical performance, body composition and appetite regulation in people with cystic fibrosis.
- Trial name
- NCT05140967
- Testing
- High Intensity Interval Training (HIIT), Moderate Continuous Intensity Training (MICT)
- Where
- 2 sites in Germany
- Volunteers
- 70 people
- Sponsor
- University of Kiel
Premature Infants
A Randomized Trial of Outpatient Oxygen Weaning Strategies in Premature Infants
The investigators hypothesize that Recorded Home Oximetry (RHO) utilization will not increase rates of respiratory-related re-hospitalizations and ED visits, and will not impair growth compared to standard oxygen management…
- Trial name
- NCT01994954
- Testing
- RHO
- Where
- 8 sites in United States
- Volunteers
- 196 people
- Sponsor
- University of Massachusetts, Worcester
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.