Clinical trials: Oxygen Disorders
Myopia
Retinal Oxygen Metabolism in Children With Myopia
The aim of the present study is to gain more information about retinal functional parameters in myopic children in Europe. For this purpose, a prospective case-control study in children aged between 8 and 13 years, as this is the…
- Trial name
- NCT07473401
- Where
- Austria
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Intensive Care, Neonatal, Neonatal Respiratory Distress Syndrome
Breastfeeding Infants Receiving Respiratory Support Trial
The purpose of this study is to assess whether two methods of breathing support in babies called 'Humidified High-Flow Nasal Cannula' oxygen (HHFNC) and 'nasal Continuous Positive Airways Pressure' (nCPAP) are compatible with…
- Conditions
- Intensive Care, Neonatal, Neonatal Respiratory Distress Syndrome, Continuous Positive Airway Pressure, Breast Feeding
- Trial name
- BIRRST (NCT02999165)
- Testing
- Breast feeding, Nasogastric feeding
- Where
- United Kingdom
- Volunteers
- 1 people
- Sponsor
- Imperial College Healthcare NHS Trust
Neonatal Disorder
Effects of Mother Position in Skin-to-skin Contact Newborn on Oxygen Saturation Levels.
The purpose of this study is to determine if the position of the mother in the first two hours after delivery, while she is in skin to skin contact with your child, influences the oxygen saturation and/or heart rate of the…
- Trial name
- NCT02585492
- Testing
- Head-of-bed elevated 15°, Head-of-bed elevated 45°
- Where
- 7 sites in Spain
- Volunteers
- 1,243 people, healthy volunteers welcome
- Sponsor
- Red Salud Materno Infantil y del Desarrollo
Colorectal Cancer, Diverticulitis of Sigmoid
Intraoperative Use of Oxygen Saturation Imaging to Assess Intestinal Perfusion
This will be a prospective, observational study of patients undergoing laparoscopic colorectal resection with anastomosis. After anastomosis creation and at the time of routine intraoperative flexible sigmoidoscopy, 4 mucosal…
- Trial name
- NCT07587619
- Testing
- Fujifilm monitoring
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- University of Southern California
Pulmonary Atelectasis, Postoperative
Effect of Different Inspired Oxygen Concentrations on Intraoperative Recruitment Outcomes in Patients Undergoing Abdominal Surgery
This study intends to evaluate the effect of different inhaled oxygen concentrations on the effect of lung recruitment in patients undergoing abdominal surgery.
- Trial name
- NCT06746181
- Testing
- Fraction of inspiration O2(FiO2)
- Where
- China
- Volunteers
- 95 people
- Sponsor
- Northern Jiangsu People's Hospital
Hypertension, Pulmonary Arterial, Out-Of-Hospital Cardiac Arrest
REstrictive Versus LIberal Oxygen Strategy and Its Effect on Pulmonary Hypertension After Out-of-hospital Cardiac Arrest (RELIEPH-study)
Background: For patients with out-of-hospital cardiac arrest (OHCA) at the intensive care unit (ICU), oxygen therapy plays an important role in post resuscitation care.
- Conditions
- Hypertension, Pulmonary Arterial, Out-Of-Hospital Cardiac Arrest, Intensive Care Unit, Oxygen Therapy
- Trial name
- RELIEPH (NCT05029167)
- Testing
- Restrictive PaO2, Low normal MAP, Liberal PaO2
- Where
- Denmark
- Volunteers
- 300 people
- Sponsor
- University of Southern Denmark
Brain Tumor, Metabolic Disturbance
Effect of Dexmedetomidine on Brain Homeostasis and Neurocognitive Outcome
Brain tumor surgery is commonly associated with different degrees of preoperative intracranial hypertension and surrounding tumor edema, elicited by tumor underlying pathophysiology.
- Conditions
- Brain Tumor, Metabolic Disturbance, Inflammatory Response, Oxygen Deficiency
- Trial name
- NCT04266665
- Testing
- Dexmedetomidine, Normal saline
- Where
- Greece
- Volunteers
- 56 people
- Sponsor
- Georgia Tsaousi
Type 2 Diabetes Mellitus
Acute Effect of Phototherapy With Light Emitting Diode (LED) on Muscle and Pulmonary Oxygen Consumption on Diabetes Mellitus
The purpose of this study is to determine the phototherapy may be adjuvant to exercise to improve muscular efficiency and increase aerobic capacity.
- Trial name
- NCT01889784
- Testing
- Phototherapy through light emitting diode (LED) - 150J, Phototherapy through light emitting diode (LED) - 300J
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Aparecida Maria Catai
Mild Traumatic Brain Injury, Hyperbaric Oxygen Therapy
Treatment of U.S. Veterans With Mild Traumatic Brain Injury With Hyperbaric Oxygen Therapy
Mild traumatic brain (mTBI) injury affects 400,000 U.S. Veterans resulting in physical, cognitive and mental health symptoms. The Department of Defense (DoD) reported 26 suicides a day from mTBI despite ongoing care for the…
- Conditions
- Mild Traumatic Brain Injury, Hyperbaric Oxygen Therapy, Depression
- Trial name
- NCT06665633
- Testing
- Oxygen 100 % Gas for Inhalation, Hyperbaric Oxygen Therapy Chamber
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Nova Southeastern University
Diabetic Foot Ulcers
Registry HBOT in DFU
Overview of available data to assess the benefits of HBOT to DFU patients
- Trial name
- NCT06693180
- Testing
- HBOT
- Where
- Netherlands
- Volunteers
- 600 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Prematurity
Oxygen Saturation and Caffeine Post-Discharge
This study aims to determine normative values of oxygen saturation in late preterm infants, and evaluate the frequency of hypoxic events in infants requiring caffeine at discharge and those not requiring it.
- Trial name
- OCPDPS (NCT02386046)
- Testing
- Pulse oxymeter measurements
- Where
- Canada
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Single Ventricle Heart Disease After Fontan Surgery
Pharmacokinetic/Pharmacodynamic Study of Udenafil in Adolescents
To determine the pharmacokinetic profile and safety of udenafil in adolescents with Fontan physiology and to assess the short-term pharmacodynamic effect of udenafil on pharmacodynamic measures of exercise capacity, ventricular…
- Trial name
- NCT02201342
- Testing
- Udenafil
- Where
- 6 sites in United States, Canada
- Volunteers
- 36 people
- Sponsor
- Mezzion Pharma Co. Ltd
Inflammatory Bowel Diseases, Children, Only
Hyperbaric Oxygen Therapy in Children With Inflammatory Bowel Diseases
The study assesses the effectiveness of hyperbaric oxygen therapy in the treatment of inflammatory bowel disease in children.
- Trial name
- NCT03576027
- Testing
- Hyperbaric Oxygen Therapy
- Where
- Poland
- Volunteers
- 30 people
- Sponsor
- Medical University of Warsaw
Bradycardia, Hypoxemia
Nose-close and Abdomen-compression in Pediatric Flexible Bronchoscopy
The nasopharyngeal oxygen (NPO) with Nose-close (NC) and Abdomen-compression (AC) technique may use for support or rescue asphyxiated infants during Flexible bronchoscopy.
- Trial name
- NPO-NC-AC (NCT01629186)
- Testing
- NPO with Nose-close and Abdomen-compression
- Where
- Taiwan
- Volunteers
- 156 people
- Sponsor
- Cho-yu Chan, MD
Coronary Heart Disease
Estimating Peak Oxygen Uptake in People Living With Coronary Heart Disease
In people living with coronary heart disease (CHD), V̇O2 peak predicts all-cause mortality. V̇O2 peak increases with regular exercise training.
- Trial name
- NCT05505344
- Testing
- VentriJect Seismofit validation
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Sheffield Hallam University
COPD Exacerbation
High Flow Oxygen Therapy in Patients Suffering From Chronic Obstructive Pulmonary Disease Exacerbation: Effects and Mechanisms of Action
Acute exacerbation of chronic obstructive pulmonary disease (COPD) is associated with poor outcome, especially when intubation is required, thus underlining the importance of optimizing non-invasive ventilatory support to avoid…
- Trial name
- Oh BPCO (NCT02371564)
- Testing
- High flow humidified oxygen, Standard flow humidified oxygen
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Angers
Substance-Related Disorders
The Effect of Aerobic Endurance Training in Patients With Drug Addiction
Physical health does not have a high priority in today's treatment of patients with substance use disorder (SUD) patients have a poor physical health not only due to injuries related to the substance abuse, but also because of…
- Trial name
- NCT02017821
- Testing
- high intensity aerobic training
- Where
- Norway
- Volunteers
- 24 people
- Sponsor
- Norwegian University of Science and Technology
Oxygen Reserve Index, Apnea
The Role of Oxygen Reserve Index (ORi) in Apneic Ventilation
Background: The Oxygen Reserve Index (ORI) is a non-invasive parameter utilizing multi-wavelength pulse co-oximetry. ORI can provide early warnings of deteriorating oxygenation before changes are reflected in SpO₂ levels.
- Conditions
- Oxygen Reserve Index, Apnea, Ventilation, Body Mass Index
- Trial name
- NCT07119866
- Testing
- OXYGEN RESERVE INDEX
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ankara City Hospital Bilkent
Idiopathic Pulmonary Fibrosis
Heart Rate Variability and Nocturnal Blood Oxygen Saturation in Patients With Idiopathic Pulmonary Fibrosis
The goal of this observational study is to compare the overnight heart rate variability (HRV) and nocturnal oxygen saturation (SpO2) in patients with idiopathic pulmonary fibrosis (IPF).
- Trial name
- NCT06027372
- Testing
- "LARGAN" ECG Holter
- Where
- Taiwan
- Volunteers
- 70 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Hypoplastic Left Heart, Surgery
NIRS in Neonatal Cardiac Surgery
Due to the small size of infants and the use of bypass machines, physicians have difficulty assessing whether the infant's brain and body is getting enough oxygen during heart surgery.
- Trial name
- NCT00166101
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Emory University
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