Clinical trials: Oxygen Disorders
Diabetic Foot, Pressure Ulcer
A Real-World Registry of Chronic Wounds and Ulcers
WOUNDJOURNEY is a longitudinal, real-world, observational registry designed to capture the full clinical course and patient journey associated with chronic wounds and ulcers.
- Conditions
- Diabetic Foot, Pressure Ulcer, Surgical Wound Dehiscence, Vasculitis
- Trial name
- WOUNDJOURNEY (NCT02280733)
- Testing
- Usual care
- Where
- United States
- Volunteers
- 300,000 people
- Sponsor
- U.S. Wound Registry
TBI (Traumatic Brain Injury)
Biomarkers in the Brain Oxygen Optimization in Severe Traumatic Brain Injury Trial
BioBOOST is a multicenter, observational study of the effect of derangements in brain physiologic parameters on brain injury biomarker levels in patients with severe traumatic brain injury.
- Trial name
- BioBOOST (NCT04565119)
- Testing
- No intervention. This is an observational study.
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- University of Pennsylvania
Anterior Wall Acute Myocardial Infarction
Evaluation of Intracoronary Hyperoxemic Oxygen Therapy in Anterior Acute Myocardial Infarction Patients (IC-HOT)
The primary objective of the study is to collect confirmatory data supporting the safety and effectiveness of SSO2 Therapy in treatment of anterior acute myocardial infarction (AMI) patients who have undergone successful…
- Trial name
- IC-HOT (NCT02603835)
- Testing
- SSO2 Therapy
- Where
- 15 sites in United States
- Volunteers
- 100 people
- Sponsor
- TherOx
Acupuncture, Postoperative Delirium (POD)
Study of Acupuncture on Postoperative Delirium in Patients With Diabetes Mellitus
1. To evaluate the effectiveness and safety of acupuncture on POD in diabetic patients undergoing surgery, to provide effective prevention and treatment measures of integrated traditional Chinese and western medicine for reducing…
- Conditions
- Acupuncture, Postoperative Delirium (POD), Diabetes Mellitus
- Trial name
- NCT05535985
- Testing
- acupuncture
- Volunteers
- 215 people
- Sponsor
- Lingling Ding
Diabetic Foot, Sleep Apnea
Impact of Sleep Apnea on Diabetic Foot Wound.
Sleep apnea syndrome (SAS) is a common comorbidity of type 1 and type 2 diabetes. A low transcutaneous oxygen tension (PtcO2) measured on the foot is pejorative prognostic factor for the healing of a diabetic foot wound.
- Trial name
- SAS-FOOT (NCT01573897)
- Where
- France
- Volunteers
- 35 people
- Sponsor
- AGIR à Dom
Cerebral Tumor, Stroke
Magnetic Resonance Imaging Evaluation of the Tissular Oxygen Saturation in Brain
The purpose of this study is to measure the tissular oxygen saturation in brain by magnetic resonance imaging on subjects and to correlate the results with near infrared spectroscopy measurements.
- Trial name
- GADOXY (NCT02317055)
- Testing
- imaging
- Where
- France
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Cerebral Ischemia
Reversing Cerebral Oxygen Desaturations Greater That 10% of Baseline Values Using NIRS in the ICU
Study objectives: The main objective of this study is to determine the feasibility of implementing measures in the intensive care unit (ICU), based on a physiological algorithm, to reverse decreases in cerebral oxygen saturation…
- Trial name
- NIRS-ICU (NCT01875055)
- Testing
- NIRS and Algorithm, NIRS derived cerebral oximetry
- Where
- Canada
- Volunteers
- 49 people
- Sponsor
- University of Manitoba
Critical Illness
Transcutaneous Partial Oxygen and Carbon Dioxide Pressures Compared With Blood Gas Values
Partial blood oxygen and carbon dioxide pressures obtained in critical ill neonates by transcutaneous sensors will be compared to respective values obtained by medically indicated arterial and capillary blood gas analyses.
- Trial name
- OxiVenT (NCT03060018)
- Testing
- Sentec (SenTec) Digital Monitoring System with OxiVenT Sensor
- Where
- Switzerland
- Volunteers
- 113 people
- Sponsor
- Vera Bernet, MD
Disorder Related to Lung Transplantation, Central Airway Stenosis
Hyperbaric Oxygen Therapy for Lung Transplantation
The objective of this study is to evaluate the effect of hyperbaric oxygen therapy (HBOT) on airway complications in post-lung transplant recipients with evidence of restricted levels of blood and oxygen in the airway tissue.
- Conditions
- Disorder Related to Lung Transplantation, Central Airway Stenosis, Airway Exudative Plaques, Airway Complications Post-Lung Transplantation
- Trial name
- NCT02363959
- Testing
- Hyperbaric Oxygen Therapy, Endobronchial Biopsy of Airway Epithelium
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Duke University
Inflammatory Bowel Disease (IBD), Crohn Disease
Hyperbaric Oxygen Therapy for Perianal Fistulizing Crohn's Disease Not Responsive or Intolerant to Conventional Care: HYPNOTIC Pilot Study
This study aims to test a new treatment called hyperbaric oxygen therapy (HBOT) for a severe type of inflammatory bowel disease called perianal Crohn's disease (PCD).
- Trial name
- HYPNOTIC (NCT06109961)
- Testing
- Oxygen Gas for Inhalation, Standard of care
- Volunteers
- 54 people
- Sponsor
- University of British Columbia
Non Invasive Test of Pulse and Oxygen Saturation
Ambulatory Measurements of Physiological Parameters
Ambulatory monitoring of physiological variables is important in following the health status of individuals in non-hospital controlled situations.
- Trial name
- LIFEBEAM (NCT01267513)
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Covid19, Hydrogen-oxygen Gas
Hydrogen-oxygen Gas Mixture Inhalation in Patients With Convalescent Coronavirus Disease 2019 (COVID-19)
This study is a multicenter, randomized, open, parallel-controlled study. Qualified subjects will randomly be assigned to the experimental arm or the control arm according to the ratio of 1:1, with age (> 60 years or ≤ 60 years)…
- Conditions
- Covid19, Hydrogen-oxygen Gas, AMS-H-03
- Trial name
- NCT04594460
- Testing
- Hydrogen-Oxygen Generator with Nebulizer, AMS-H-03, OLO-1 Medical Molecular Sieve Oxygen Generator
- Where
- 2 sites in China
- Volunteers
- 198 people
- Sponsor
- Guangzhou Institute of Respiratory Disease
Respiratory Distress Syndrome, Lower Respiratory Tract Infection
A Low-Resource Oxygen Blender Prototype for Use in Modified Bubble CPAP Circuits
Purpose: Using a novel oxygen blender prototype with modified bCPAP to manage children 1 month to 5 years of age hospitalized with respiratory distress due to lower respiratory tract infection (LRTI) in low-resource settings is…
- Trial name
- NCT04311320
- Testing
- Low-Resource Oxygen Blender
- Where
- Cambodia
- Volunteers
- 33 people
- Sponsor
- University of Minnesota
Renal Disease
Increased Renal Oxygenation and Angiotensin Converting Enzyme Inhibition
It is well established that renal hypoxia is associated with the development of renal injury. The purpose of this study is measure the alterations in renal blood oxygenation after angiotensin II converting enzyme inhibition.
- Trial name
- NCT01545479
- Testing
- captopril 25mg
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Instituto de Cardiologia do Rio Grande do Sul
Severe Traumatic Brain Injury
Brain Tissue Oxygen Monitoring in Traumatic Brain Injury (TBI)
Traumatic brain injury (TBI) is a major cause of death and disability, with an estimated cost of 45 billion dollars a year in the United States alone.
- Trial name
- BOOST 2 (NCT00974259)
- Testing
- Management protocol based on pBrO2 and ICP values., Management protocol based on ICP values only.
- Where
- 10 sites in United States
- Volunteers
- 122 people
- Sponsor
- University of Pennsylvania
Cystitis, Radio Induced
Radiation Induced Cystitis Treated With Hyperbaric Oxygen - A Randomized Controlled Trial
The primary objective of this study is to assess the relief of symptoms after Hyperbaric Oxygen Therapy (HBOT) in patients with late radiation cystitis by having Expanded Prostate cancer Index Composite (EPIC)symptom estimation…
- Trial name
- RICH-ART (NCT01659723)
- Testing
- Hyperbaric Oxygen
- Where
- 5 sites in Denmark, Finland and 2 more
- Volunteers
- 75 people
- Sponsor
- Göteborg University
Infant, Newborn, Hypertension, Pulmonary
Early Inhaled Nitric Oxide for Respiratory Failure in Newborns
This prospective, randomized controlled trial tested whether initiating iNO therapy earlier would reduce death and reduce the use of extracorporeal membrane oxygenation (ECMO) -- temporary lung bypass -- therapy compared with the…
- Conditions
- Infant, Newborn, Hypertension, Pulmonary, Persistent Fetal Circulation Syndrome, Pneumonia, Aspiration
- Trial name
- Early iNO (NCT00005773)
- Testing
- Inhaled Nitric Oxide, Standard iNO therapy
- Where
- 18 sites in United States
- Volunteers
- 302 people
- Sponsor
- NICHD Neonatal Research Network
Chronic Obstructive Pulmonary Disease (COPD), Muscle Oxygenation
Analysis of Muscle Oxygen Saturation and Functional Variables During Physical Capacity Assessments in Patients With COPD
This experimental pre-post intervention study aims to evaluate the effect of a respiratory physiotherapy and combined strength and cardiovascular training program on muscle oxygen saturation and functional capacity in patients…
- Conditions
- Chronic Obstructive Pulmonary Disease (COPD), Muscle Oxygenation, Exercise, Respiratory Physiotherapy
- Trial name
- NCT06968273
- Testing
- Combined respiratory physiotherapy and cardiovascular-strength training program
- Where
- Portugal
- Volunteers
- 15 people
- Sponsor
- University of Extremadura
Pulmonary Atelectasis
Effects of Different Oxygen Concentrations on Lung Ultrasound Score During Spontaneous Ventilation
The goal of this study is to observe the effects of different oxygen concentrations during preoxygenation in spontaneous breathing patients with modified lung ultrasound scores before induction of general anesthesia.
- Trial name
- NCT05850988
- Testing
- %80 Oxygen concentration, %100 Oxygen concentration
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Diskapi Teaching and Research Hospital
Pulmonary Vascular Disorder, Pulmonary Artery Hypertension
HA Residents With PVD, Pulmonary Artery Pressure (PAP) Assessed at HA (2840m) With and Without Supplemental Oxygen Therapy (SOT)
To study the effect of SOT in patients with pulmonary vascular diseases (PVD) defined as pulmonary arterial hypertension or chronic thromboembolic pulmonary hypertension (PH) who permanently live >2500m on pulmonary artery…
- Conditions
- Pulmonary Vascular Disorder, Pulmonary Artery Hypertension, Chronic Thromboembolic Pulmonary Hypertension
- Trial name
- NCT06084559
- Testing
- Supplemental oxygen therapy
- Where
- Switzerland
- Volunteers
- 24 people
- Sponsor
- University of Zurich
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.