Clinical trials: Oxygen Disorders
Smog-Induced Pneumonia, Pneumonia
Effects of Buteyko Breathing Versus Incentive Spirometry on Oxygen Saturation, Dyspnoea, Exercise Tolerance, and Sputum Clearance in Patients With Smog Induced Pneumonia
The current study will be a single-blind, parallel-group randomized controlled trial involving 62 patients diagnosed with smog-induced pneumonia.
- Trial name
- NCT07759583
- Testing
- Buteyko Breathing Technique (BBT), Incentive Spirometry (IS)
- Where
- Pakistan
- Volunteers
- 62 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Chronic Obstructive Pulmonary Disease (COPD)
Phase IV O2 Consumption Study in COPD Patients.
A Phase IV study evaluating changes in oxygen consumption and cardiac function in Subjects with Chronic obstructive pulmonary disease (COPD) with resting hyperinflation after administration of Symbicort pMDI 160/4.5 μg.
- Trial name
- NCT02533505
- Testing
- Budesonide 160 mcg and formoterol fumarate dihydrate 4.5 mcg Inhalation aerosol
- Where
- 5 sites in United States
- Volunteers
- 51 people
- Sponsor
- AstraZeneca
COPD, Chronic Hypoxemic Respiratory Failure
Automated Oxygen Titration with O2matic Home Oxygen Therapy (O2matic HOT) Phase 1
O2matic HOT is a further development of O2matic and is intended for home oxygen use with patients in need of long-term oxygen treatment (LTOT).
- Trial name
- O2matic-HOT1 (NCT04606290)
- Testing
- O2matic HOT, Oxygen concentrator
- Where
- 2 sites in Denmark
- Volunteers
- 10 people
- Sponsor
- Hvidovre University Hospital
Hypoxic Brain Injury, Hypothermia
Jugular Venous Oxygen Saturation During Therapeutic Hypothermia After Cardiac Arrest
The purpose of this study is to understand what happens to cerebral metabolism during therapeutic hypothermia for hypoxic brain injury following cardiac arrest.
- Trial name
- SjO2 (NCT00870610)
- Testing
- retrograde jugular venous cannulation
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- Policlinico Hospital
ICU Acquired Weakness, Sepsis
ICU Combined Assessment of Cardio-Respiratory Exercise
This study aims to investigate how sepsis and critical illness can impair the cardiovascular system and microcirculation in intensive care unit (ICU) patients, which can lead to long-lasting muscle weakness/dysfunction or…
- Conditions
- ICU Acquired Weakness, Sepsis, Shock, Critical Illness
- Trial name
- ICU-CARE (NCT06193980)
- Where
- 2 sites in Canada
- Volunteers
- 50 people
- Sponsor
- University of Manitoba
Respiratory Failure
The Efficacy of the Whisperflow CPAP System Versus Nasal High Flow in Patients at High Risk for Postextubation Failure
The purpose of this study is to compare the effect of continuous positive airway pressure (CPAP) delivered by the variable generator WhisperFlow System with high flow nasal cannula oxygen therapy in mechanically ventilated…
- Trial name
- NCT02918786
- Testing
- Nasal high-flow, CPAP
- Where
- Thailand
- Volunteers
- 140 people
- Sponsor
- Ramathibodi Hospital
Brain Death
ORI and ETCO₂ Relationship With Arterial Blood Gas During Apnea Test
This observational study aims to evaluate the relationship between the Oxygen Reserve Index (ORI) and End-Tidal Carbon Dioxide (ETCO2) values with arterial blood gas parameters in patients undergoing the apnea test for the…
- Trial name
- NCT06983990
- Testing
- No intervention (observational monitoring only)
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Subarachnoid Hemorrhage, Aneurysmal
Multimodality Monitoring Directed Management of Aneurysmal Subarachnoid Haemorrhage
Aneurysmal subarachnoid haemorrhage (aSAH) affects up to 10,000 individuals per year in the UK. It accounts for ~5% of strokes, but is responsible for about 25% quality-adjusted life years (QALYs) lost due to stroke.
- Trial name
- MMMSAH (NCT03010709)
- Volunteers
- 100 people
- Sponsor
- Adel Helmy
COPD, COPD - Chronic Obstructive Pulmonary Disease
Respiratory Oxygen Adherence Monitor for Chronic Obstructive Pulmonary Disease Patients
The goal of this clinical trial is to test a device called "ROAM" that is being developed to see how patients with chronic obstructive pulmonary disease (COPD) use oxygen therapy over a long period of time.
- Trial name
- ROAM (NCT06874101)
- Testing
- Activated ROAM System with User Feedback
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Barron Associates, Inc.
Sepsis, Thiamine Deficiency
Effect of Thiamine on Serum Glucagon And Reactive Oxygen Species (ROS)
This research is a clinical trial with a Randomized Controlled Trial (RCT) design. The purpose is to identify the effect of intravenous thiamine administration compared to normal saline placebo on glucagon levels and ROS levels…
- Trial name
- NCT05663164
- Testing
- Vitamin B
- Where
- Indonesia
- Volunteers
- 30 people
- Sponsor
- Universitas Sumatera Utara
Cerebral Stroke
Hyperbaric Oxygen Therapy After Stroke - PILOT
The goal of this pilot study is to establish more information about hyperbaric oxygen therapy for this group of patients, and give us more information of how to initiate the best possible main study.
- Trial name
- NCT04149379
- Testing
- Hyperbaric oxygen
- Where
- Norway
- Sponsor
- Norwegian Underwater Intervention (NUI)
Stroke
Measurement of Cerebral Oxygen Extraction Fraction Using MRI Technique
All images in this study were acquired on a 1.5 T Sonata whole body scanner (Siemens Medical Inc., Erlangen, Germany) using 2D multi-echo gradient echo/spin echo sequence and 2D single-shot gradient echo-planar imaging sequence…
- Trial name
- NCT00166920
- Where
- Taiwan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Physiological Responses, Pilates Exercise
Effect of Muscle Strengthening Training with Pilates Reformer on Overweight/obese and Normal Body Weight Women (PRET)
This study investigates the physiological responses and the metabolic burden of a Pilates Reformer strength training session in physically inactive premenopausal women with a body mass index of 18-24.9 and 25.01-39.9.
- Conditions
- Physiological Responses, Pilates Exercise, Overweight and Obese Women, Energy Expenditure
- Trial name
- PRET (NCT06675162)
- Testing
- Pilates Reformer Training
- Where
- 2 sites in Greece
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Peripheral Arterial Disease
Analysis of Arterial Waveforms and Oxygen Pressure During Supervised Exercise for Peripheral Artery Disease
The goal of this observational study is to assess the evolution of oxygen pressure and arterial waveform during supervised exercise therapy in patients with peripheral arterial disease.
- Trial name
- WAVESUPEX (NCT05818046)
- Testing
- transcutaneous oxygen pressure, Supervised Exercise therapy
- Where
- France
- Volunteers
- 36 people
- Sponsor
- University Hospital, Caen
Acute Kidney Injury
Association of Tissue Oxygen Saturation With Postoperative Acute Kidney Injury in Double Valves Replacement Surgery
To investigate the relationship of tissue oxygenation of different organs and tissue beds (e.g., a tissue bed on the arm vs. leg vs.
- Trial name
- NCT03323203
- Testing
- FORE-SIGHT Elite, CASMED, Inc., Branford, Connecticut, USA
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Xijing Hospital
Chronic Obstructive Pulmonary Disease
Effects of Supplemental Oxygen Delivered by a Portable Oxygen Concentrator Compared to a Liquid Oxygen Device in COPD
The aim of this study is to investigate the effects of supplemental oxygen on blood oxygenation at rest in Patients with severe to very severe COPD comparing the portable oxygen concentrator (Activox™ 4L) to a liquid continuous…
- Trial name
- NCT03174210
- Testing
- liquid oxygen device (LOD), portable oxygen concentrator (POC)
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Schön Klinik Berchtesgadener Land
Neuropsychiatric Sequelae of Carbon Monoxide Poisoning
Hyperbaric Oxygen Therapy and SPECT Brain Imaging in Carbon Monoxide Poisoning
That SPECT brain imaging tracks and is consistent with clinical history and physical exam as well as cognitive testing.
- Trial name
- NCT00596180
- Testing
- HBOT
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Paul G. Harch, M.D.
Hypoxemic Respiratory Failure
A Pilot Study Comparing Oxygen Delivery Via Helmet Interface Versus High Flow Nasal Cannula
Our main objective is to collect feasibility data on helmet NIPPV and other clinical elements in to eventually prepare for a full scale randomized trial based on findings of this pilot study.
- Trial name
- NOVA-pilot (NCT04035460)
- Testing
- Helmet, High Flow Nasal Oxygen
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Baystate Medical Center
COVID-19, Endothelial Function
Diagnostics of Coronavirus Disease 2019 Cardiovascular Complications
Aim of this prospective, observational, multi-centered, randomized study is to detect cardiovascular complications in patients after coronavirus infection.
- Conditions
- COVID-19, Endothelial Function, Diastolic Dysfunction, Oxygen Consumption
- Trial name
- NCT05608603
- Testing
- Portable cardiac monitor "CardioQvark", Cardiorespiratory stress test, Analysis of exhaled air using the Compact PTR-MS proton mass spectrometer
- Where
- Russia
- Volunteers
- 100 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Heart Failure, Chronic Heart Failure
Wearable Tissue Oximetry During Arm Cuff Occlusion, Walking, and Standing Tests in Outpatients With Chronic Heart Failure
This prospective, single-center, observational pilot study evaluated an investigational wearable tissue oximeter (NIRSense Argus Oximetry System, also called Envello Core) in adult outpatients with chronic heart failure in New…
- Trial name
- NCT07874386
- Testing
- Argus Oximetry System
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- NIRSense Inc.
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