Clinical trials: Oxygen Disorders
Respiratory Distress Syndrome (Neonatal), Respiratory Distress of Newborn
How Different Levels of CPAP Affect Oxygen Delivery and Lung Expansion in Preterm Infants
With this study, it is expected to learn more about preterm babies on breathing support with nasal continuous positive airway pressure (nCPAP).
- Trial name
- NCT07674953
- Testing
- Effective oxygen delivery and lung expansion measurement
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- University of Arkansas
AML, NHL
A Randomized Phase II Study of Hyperbaric Oxygen in Improving Engraftment in Umbilical Cord Blood Stem Cell Transplant
The UCB transplant is a type of stem cell transplant used to treat cancer of the blood or lymph glands. The UCB transplant has advantages over other types of transplants such as ease of obtaining the umbilical cord blood, absence…
- Conditions
- AML, NHL, Hodgkin Disease, All
- Trial name
- HBO-UBC (NCT03739502)
- Testing
- Hyperbaric oxygen
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- University of Rochester
Idiopathic Pulmonary Arterial Hypertension, Cardiomyopathy
Comparison of Inhaled Nitric Oxide and Oxygen in Participants Reactivity During Acute Pulmonary Vasodilator Testing
The primary purpose of this study is to compare the number of participants with reversible pulmonary hypertension (vasoreactivity) due to nitric oxide for inhalation and oxygen as compared to 100% oxygen.
- Trial name
- NCT00626028
- Testing
- Nitric Oxide for inhalation, Oxygen, Nitric Oxide plus Oxygen
- Where
- 18 sites in United States, France and 3 more
- Volunteers
- 136 people
- Sponsor
- Mallinckrodt
Birth Asphyxia, Premature Birth
Oxygen Toxicity in the Resuscitation in Extremely Premature Infants
The investigators hypothesize that using low oxygen concentrations during resuscitation of extremely premature infants will avoid oxidative stress derived damage and improve outcome.
- Trial name
- OXTOX (NCT00494702)
- Testing
- Resuscitation
- Where
- Spain
- Volunteers
- 88 people
- Sponsor
- Fundacion Para La Investigacion Hospital La Fe
COPD (Chronic Obstructive Pulmonary Disease), Intersitital Lung Disease
MoblO2 to Maintain Oxygenation
Many patients with chronic lung disease (e.g., chronic obstructive pulmonary disease (COPD) or interstitial lung disease (ILD)) require supplemental oxygen (O2) at some point during their disease course.
- Trial name
- SSeifert (NCT07704567)
- Testing
- MoblO2 controls O2 flow, MoblO2 does not control flow
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Minnesota HealthSolutions
Chronic Obstructive Lung Disease, Pulmonary Fibrosis
Comparative Study of 3 Portable Oxygen Concentrators During a 6-minute Walk Test in Patients With Chronic Lung Disease
Background: Portable oxygen concentrators (POCs) featuring the latest integrated oxygen conserving devices (OCDs) provide greater patient accessibility and mobility during ambulation and travel.
- Trial name
- NCT01653730
- Testing
- Eclipse 3 portable oxygen concentrator, EverGo portable oxygen concentrator, iGo portable oxygen concentrator
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- Ottawa Hospital Research Institute
Psychosis, Schizophrenia
Normobaric Oxygen Therapy for Individuals With First-Episode Psychosis
Single-blind, randomized controlled trial of normobaric oxygen therapy among individuals with first-episode psychosis: Effects on symptomatology and cognition.
- Conditions
- Psychosis, Schizophrenia, First-episode Psychosis
- Trial name
- NCT04368039
- Testing
- Normobaric Oxygen
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Nicholas Breitborde
Pulmonary Arterial Hypertension Related to Eisenmenger Physiology
Effects of Tracleer (Bosentan) on Pulmonary Arterial Hypertension Related to Eisenmenger Physiology
This study evaluates the effects of bosentan on oxygen saturation, hemodynamics and exercise capacity in patients with pulmonary arterial hypertension related to Eisenmenger physiology.
- Trial name
- NCT00317486
- Testing
- bosentan
- Volunteers
- 54 people
- Sponsor
- Actelion
Anterior Wall Acute Myocardial Infarction
Evaluation of Intracoronary Hyperoxemic Oxygen Therapy in Anterior Acute Myocardial Infarction Patients (IC-HOT)
The primary objective of the study is to collect confirmatory data supporting the safety and effectiveness of SSO2 Therapy in treatment of anterior acute myocardial infarction (AMI) patients who have undergone successful…
- Trial name
- IC-HOT (NCT02603835)
- Testing
- SSO2 Therapy
- Where
- 15 sites in United States
- Volunteers
- 100 people
- Sponsor
- TherOx
Heart Failure, Central Sleep Apnea
The Impact of Low Flow Nocturnal Oxygen Therapy on Hospital Admissions and Mortality in Patients With Heart Failure and Central Sleep Apnea
The purpose of this trial is to evaluate the long-term effects of Nocturnal Oxygen Therapy (NOXT) on the mortality and morbidity of patients with stable heart failure and a reduced ejection fraction (HFrEF), already receiving…
- Trial name
- NCT03745898
- Testing
- Oxygen, Room Air
- Where
- 26 sites in United States
- Volunteers
- 98 people
- Sponsor
- Brigham and Women's Hospital
Chronic Obstructive Pulmonary Disease
Gas Usage for Those With COPD Who Experience Low Oxygen Levels During Activities Only
Several studies have described the use of supplemental oxygen during exertion or activities of daily living (ambulatory oxygen) in study populations that have different characteristics.
- Trial name
- NCT00546299
- Testing
- oxygen
- Volunteers
- 27 people
- Sponsor
- West Park Healthcare Centre
Chronic Wounds, Obliterating Arteriopathy of the Lower Limbs
Clinical Evaluation of an Innovative Non-contact Optical Device for Skin Oxygenation Imaging
According to international consensus, information on the level of skin oxygenation is necessary for the diagnostic management of chronic wounds.
- Trial name
- IMOXY (NCT05187676)
- Testing
- Oxygen saturation measurement using the IPAM device, Transcutaneous oxygen partial pressure (TcPO2) using the PeriFlux6000 device
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Central Hospital, Nancy, France
Foreign Bodies, Tumor
The Effects of High-flow Nasal Oxygen on Oxygenation During Rigid Bronchoscopy Under General Anesthesia in Pediatric Patients
The aim of this study is to evaluate the effect of high-flow nasal cannula oxygen administration on maintenance of oxygenation and removal of carbon dioxide during apnoeic period in pediatric patients undergoing general…
- Conditions
- Foreign Bodies, Tumor, Stenosis of Trachea, Bronchus
- Trial name
- NCT03905733
- Testing
- Optiflow
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Yonsei University
Pneumoperitoneum
Effect of Pneumoperitoneum on Cognitive Function and Regional Cerebral Oxygen Saturation
The investigators hypothesized that the pneumoperitoneum with reverse Trendelenburg position could alter the rSO2 and early postoperative cognitive function.
- Trial name
- rSO2pneumo (NCT01826955)
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Gachon University Gil Medical Center
COVID-19
Hyperbaric Oxygen Therapy (HBOT) as a Treatment for COVID-19 (COVID-19) Infection
Patients who meet inclusion criteria will be randomized into treatment vs control group. Treatment groups will undergo Hyperbaric Oxygen Therapy (HBOT) and compared to the control group.
- Trial name
- NCT04343183
- Testing
- Hyperbaric Oxygen Therapy
- Where
- United States
- Sponsor
- Ochsner Health System
Hodgkin Lymphoma, Adult, Cardiovascular Diseases
Physical Capacity in Hodgkin Lymphoma Survivors
The study aims to investigate if physical capacity obtained in the cardiopulmonary exercise test can predict cardiovascular alterations in Hodgkin Lymphoma (HL) Survivors.
- Conditions
- Hodgkin Lymphoma, Adult, Cardiovascular Diseases, Radiation Effect, Chemotherapy Effect
- Trial name
- NCT04636255
- Testing
- Physical Characteristics, Assessment of Heart rate variability, Blood Pressure and Cardiac Autonomic Control
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- University of Sao Paulo General Hospital
COPD Diagnosed
Evaluation of a Simple Clinical Test to Detect the Risk of Falling in Patients With BPCO and Research for Predictive Factors of Fall Risk.
The risk of falling in increased in patients with Chronic Obstructive Pulmonary Disease. To date, a screening test (the Berg Balance scale, BBS) is used to evaluate this risk but it spends 20 to 30 minutes to complete.
- Trial name
- Equil-BPCO (NCT03152344)
- Testing
- Timed Up and Go
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Clermont-Ferrand
Heart Failure, Diastolic
Mechanisms and Management of Exercise Intolerance in Older Heart Failure Patients
Heart failure with preserved ejection fraction (HFpEF) is the fastest growing form of heart failure with a high morbidity and mortality rate, and is associated with severe exercise intolerance.
- Trial name
- NCT03111017
- Testing
- Exercise Training
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Arlington
Sleep Apnea, Metabolic Syndrome
Improving the STOP-Bang Screening Questionnaire for Patients With Sleep Apnea
The study is being conducted to test the ability of a simple questionnaire to detect mild, moderate or severe obstructive sleep apnea.
- Trial name
- NCT01610648
- Where
- United States
- Volunteers
- 258 people
- Sponsor
- Tufts Medical Center
Systemic Oxygenation vs ROS Formation in TBI Patients
ROS in TBI Patients in Relation to Level of Oxygenation.
This project an observational study performed on patients with severe Traumatic Brain Injury (TBI) treated at Neurosurgical ICU (NICU) at Karolinska University Hospital.
- Trial name
- ROS-TBI (NCT05101278)
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Region Stockholm
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.