Clinical trials: Oxygen Inhalation Therapy
- Condition Oxygen Inhalation Therapy
- Funder type Industry (pharma, biotech, devices)
- Accepts healthy volunteers yes
Healthy, Hypoxia
Prospective Study to Validate the Clinical Accuracy of the Norbert Device to Measure Oxygen Saturation
The purpose of this study is to evaluate the SpO2 accuracy and performance of the Norbert Device during non-motion conditions over the range of 70-100% SaO2 as compared to arterial blood samples assessed by CO-oximetry for SpO2…
- Trial name
- NCT05685654
- Testing
- Norbert Device
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Norbert Health
Lung Disease
Evaluation of Sleep Mode Within the Respironics SimplyGo Portable Oxygen Concentrator
The SimplyGo Study is a single site, cross-over study which aims to enroll a maximum of 30 participants (to allow for 20 completed data sets) with a prescription for nocturnal oxygen, and meeting all eligibility criteria.
- Trial name
- NCT01679301
- Testing
- Pulse Dose (Sleep Mode), Continuous Dose
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Philips Respironics
Oxygen Saturation
Accuracy Performance Verification of the INVOS™ PM7100 System in Adults
Prospective, observational, post-market, verification study to ensure compliance to the ISO 80601-2-85:2021 standard
- Trial name
- NCT06581835
- Testing
- Observational
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Medtronic - MITG
Acne Vulgaris
Clinical Trial on the Effects and Side Effects of ProOxy in the Treatment of Acne
This study was conducted to determine the effects and side effects of ProOxy facial spray in the treatment of acne.
- Trial name
- NCT01682200
- Testing
- ProOxy
- Where
- 2 sites in Philippines
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Medivet Pty Ltd
Healthy
WatchPAT SpO2 Validation Study
Validate the SpO2 accuracy of the WatchPAT compared to arterial blood CO-Oximetry
- Trial name
- NCT06947447
- Testing
- No intervention
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Itamar-Medical, Israel
SpO2 (Peripheral Oxygen Saturation) Measurement Validation
Philps FAST2022 picoSAT Pulse Oximetry Desaturation Study
Validation study to compare the accuracy of non-invasive Philips SpO2 sensors in detecting blood oxygen levels compared to invasive methods requiring a blood draw and lab analysis.
- Trial name
- NCT05683366
- Testing
- No Intervention
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Philips Clinical & Medical Affairs Global
Hypoxia, Desaturation of Blood
SpO2 Accuracy Low Saturation Validation of the OxySoftN Sensor
To compare prototype pulse oximeter saturation measurements, during normal to low saturation, to saturation measurements made by a multi-wavelength CO-oximeter, taken from arterial blood samples from healthy human subjects.
- Trial name
- NCT04811963
- Testing
- Non-Invasive Controlled Hypoxia
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Medtronic - MITG
Validation Study
The Sunrise SpO2 and Pulse Rate Accuracy Validation Study
The purpose of this study is to evaluate the SpO2 accuracy performance of the Sunrise Sensor 2 placed at the tip of the chin during non-motion conditions over the range of 70-100% by comparison to SaO2 values determined from…
- Trial name
- S2-SOPRAV (NCT05386836)
- Testing
- Pulse oximeter validation population
- Where
- Belgium
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Sunrise
Diabetic Ulcer
Evaluation of Topical Wound Oxygen (two2) Therapy
The purpose of this study is to evaluate the efficacy of the Topical Wound Oxygen (two2) therapy system on the healing of diabetic lower extremity ulcers.
- Trial name
- NCT00871312
- Testing
- Topical wound oxygen therapy
- Where
- 3 sites in United States, Canada
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- AOTI Ltd.
SpO2, Nasal Alar Collapse, Bilateral
Project Mountain - Comparing SpO2 and SaO2 for Accuracy
The main goal of this study is to look at the performance of the neonatal, infant, and pediatric Philips SpO2 sensors with the Philips FAST Pulse Oximetry technology.
- Conditions
- SpO2, Nasal Alar Collapse, Bilateral, Oxygen, Measurement
- Trial name
- NCT06372106
- Testing
- SaO2 Sampling
- Where
- 5 sites in United States
- Volunteers
- 560 people, healthy volunteers welcome
- Sponsor
- Philips Clinical & Medical Affairs Global
Sleep-related Respiratory Disturbance
Effects of Mild Hypobaric Hypoxia on Oxygen Saturation During Sleep
Ascent to altitude lowers oxygen saturation. In addition, sleep lowers oxygen saturation at any altitude. In a prior study, we observed that sleep at 8000 feet resulted in pronounced reduction in oxygen saturation, but did not…
- Trial name
- NCT00659009
- Testing
- Reduced barometric pressure, Sea level equivalent barometric pressure
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- The Boeing Company
Healthy
An Invasive Controlled Desaturation Study to Determine the Accuracy of the CART-I Pulse Oximeter
A pulse oximeter is used for continuous monitoring of peripheral oxygen saturation (SpO2) and plays an important role in the early detection of hypoxia, guiding the titration of supplemental oxygen, and reducing the need for…
- Trial name
- NCT05693961
- Testing
- CART-I plus
- Where
- South Korea
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Sky Labs
Hypoxia
N600X Low Saturation Accuracy Validation
To compare pulse oximetry saturation measurements, during normal to low saturation, to saturation measurements made by a multi-wavelength CO-oximeter, taken from arterial blood samples from healthy human subjects.
- Trial name
- NCT05532670
- Testing
- Non-Invasive Controlled Hypoxia
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Medtronic - MITG
Transcutaneous Oxygen Tension
Comparative Study Evaluating Performance of Celliant Fibers on Tissue Oxygenation
The study will evaluate changes in transcutaneous oxygen tension (tcPO2,), and the inferred change in local cutaneous blood flow, in healthy subjects wearing a control and a 100% Celliant® fiber upper torso garment.
- Trial name
- NCT02798640
- Testing
- Celliant, Control
- Where
- United States
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Kristopher Washington
Peripheral Arterial Disease
Using SnapshotNIR With Provocative Leg Maneuver for PAD Assessment
The objective of this trial is to determine if Near-infrared spectroscopy (NIRS) can accurately evaluate the degree of Peripheral Arterial Disease (PAD) during a Provocative Elevation Maneuver of the Lower Extremity (PEMLE) test…
- Trial name
- NCT06237621
- Testing
- SnapshotNIR imaging
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Kent Imaging Inc
Depression
Exploratory Study of the Effects of Vortioxetine (Lu AA21004) on Cognition and Blood Oxygen Level Dependent (BOLD) Functional Magnetic Resonance Imaging (fMRI) Signals in Subjects Remitted From Depression and in Controls
The purpose of this study is to determine if Vortioxetine 20 mg/day will lead to changes in neural activity (BOLD signal), as measured using fMRI, in brain areas associated with executive functioning and memory during cognitive…
- Trial name
- NCT01607125
- Testing
- Vortioxetine (Lu AA21004)
- Where
- United Kingdom
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- H. Lundbeck A/S
Opioid-Induced Respiratory Depression, Postoperative Complications (Cardiopulmonary)
Pupillometry in Identifying Risk of Postoperative Opioid-induced Respiratory Depression in Children Undergoing Tonsillectomy
This study will evaluate whether quantitative pupillometry measurements can be used to identify children at risk for postoperative opioid-induced respiratory depression (OIRD) following tonsillectomy.
- Conditions
- Opioid-Induced Respiratory Depression, Postoperative Complications (Cardiopulmonary), Respiratory Complications Due to Anesthesia
- Trial name
- NCT07573150
- Testing
- Infrared Pupillometry
- Where
- 2 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- NeurOptics Inc
Healthy
Repeatability and Reproducibility of Oxygen Reserve Index (ORi)
This study is designed to evaluate the repeatability and reproducibility of ORi using an investigational Masimo rainbow sensor and FDA cleared rainbow sensors connected to the Masimo Radical-7 pulse oximeter and Masimo Root…
- Trial name
- NCT05636098
- Testing
- Masimo Rainbow Sensors
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Masimo Corporation
Non-healing Wounds
Effect of Natrox Oxygen Wound Therapy on Non-healing Wounds and Implication of Remote Monitoring and Telehealth for Management in the Home.
Single center pilot study examining the effect of Natrox topical oxygen therapy on chronic wounds along with the introduction of remote monitoring and telehealth for home care management.
- Trial name
- NCT04746573
- Testing
- Natrox Topical Oxygen Therapy
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Inotec AMD Limited
Oxygen Saturation
Nellcor™ Investigational Device Sitting-Walking Study
To examine pulse rate and blood oxygen saturation accuracy of the Nellcor™ Investigational Device during non-motion and walking motion conditions in a diverse patient population through non-invasive means
- Trial name
- NCT07234279
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Medtronic - MITG