Clinical trials: Oxygen Saturation
Healthy, Aging
The Change of Tissue Oxygen Saturation Following Volatile Anesthesia
General anesthesia can affect tissue oxygen saturation and microcirculatory reactivity. However, the differences in microcirculation caused by anesthetic methods have not been well studied.
- Trial name
- NCT03060798
- Testing
- Desflurane, Near-infrared spectroscopy monitor
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Pusan National University Hospital
Acute Myocardial Infarction, STEMI
Delivery SSO2 Therapy for 60 Min in Anterior MI Patients With PCI ≤ 6 Hours of Symptoms Onset Compared to Standard.
A multi-center randomized post-approval evaluation of delivery of intracoronary hyperoxemic supersaturated Oxygen therapy for 60 minutes in anterior AMI patients with successful reperfusion (via PCI) within 6 hours after onset of…
- Trial name
- NCT04743245
- Testing
- TherOx DownStream System, PCI
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- TherOx
Surgery, Thyroid
The Effects of Different Degrees of Head-of-bed Elevation
The patient's position is important for ensuring patient comfort and preventing complications after thyroidectomy. This study was carried out to determine the effects of different degrees of head-of-bed elevation on the…
- Conditions
- Surgery, Thyroid, Nursing Caries
- Trial name
- NCT03816371
- Testing
- Head-of-bed elevation
- Volunteers
- 114 people
- Sponsor
- Necmettin Erbakan University
Blood Pressure, Respiration
Verification Protocol for the Cloud DX Vitaliti Continuous Vital Signs Monitor (VERDICT-2)
The VERDICT-2 verification study will examine the accuracy of the Cloud DX Vitaliti Continuous Vital Signs Monitor (Model: CVSM-1A) in an ambulatory context with healthy participants.
- Conditions
- Blood Pressure, Respiration, Pulse Rate, Oxygen Saturation
- Trial name
- VERDICT-2 (NCT05886153)
- Testing
- Vitaliti Continuous Vital Sign Monitor Model CVSM-1A
- Where
- Canada
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Hamilton Health Sciences Corporation
Hypoxia, Hypercapnia
Effect of FFP2 Masks on Peripheral Oxygen Saturation and Pulse Rate During the COVID-19 Pandemic
aim of this research is to evaluate the effects of FFP2/N95 masks on peripheral oxygen saturation and pulse rate in dental professionals
- Conditions
- Hypoxia, Hypercapnia, COVID-19 Pandemic
- Trial name
- NCT05188651
- Testing
- face masks
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Catholic University of the Sacred Heart
Tachycardia, Hypertension
To Observe Haemodynamic Parameters Including, Heart Rate, Blood Pressure, Respiratory Rate , and Oxygen Saturation, With or Without Giving Reversal Agent on Extubation, in Patients Receiving Single Shot of Atracurium , and to Observe Post Operative Residual Paralysis and Airway Reflexes in PACU.
The goal of this clinical trial is to to observe the haemodynamic parameters including Heart Rate Blood pressure Respiratory rate and Oxygen Saturation with or without giving reversal agent on extubation in patients receiving…
- Conditions
- Tachycardia, Hypertension, Hypoxia, Hyperventilation
- Trial name
- NCT07097441
- Testing
- neostigmine (reversal agent)
- Where
- Pakistan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ziauddin University
Generalised Melanin Pigmentation, Pulse Oximetry
Oxygen Saturations Across Tones of Skin
Pulse oximetry, or SpO2, is a vital sign used across healthcare systems to gauge how much oxygen blood is carrying as a percentage of the maximum it could carry.
- Trial name
- O2SATS (NCT06298422)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, San Diego
Kidney Injury, Acute, Transcatheter Aortic Valve Implantation
Renal Regional Oxygen Saturation During Transcatheter Aortic Valve Implantation
This prospective observational study evaluates the association of peri-procedural changes in renal regional oxygen saturation and post-procedural acute kidney injury in patients undergoing transcatheter aortic valve implantation.
- Trial name
- NCT04921475
- Testing
- Regional oxygen saturation monitoring
- Where
- South Korea
- Volunteers
- 65 people
- Sponsor
- Seoul National University Hospital
COVID, Hypoxic Respiratory Failure
Incline Positioning in COVID-19 Patients for Improvement in Oxygen Saturation
COVID-19 is a respiratory illness caused by SARS-CoV-2 with a range of symptoms from mild, self-limiting respiratory tract infections to severe progressive pneumonia, multiorgan dysfunction and death.
- Trial name
- UPSAT (NCT04344561)
- Testing
- Postural Positioning
- Where
- 2 sites in United States
- Volunteers
- 7 people
- Sponsor
- Johns Hopkins University
Premature Infants, Bronchopulmonary Dysplasia
Optimization of Saturation Targets And Resuscitation Trial (OptiSTART)
This study is designed to answer one of the fundamental gaps in knowledge in the resuscitation of preterm infants at birth: What is the optimal target oxygen saturation (SpO2) range that increases survival without long-term…
- Conditions
- Premature Infants, Bronchopulmonary Dysplasia, Intraventricular Hemorrhage, Neurodevelopmental Outcomes
- Trial name
- OptiSTART (NCT05849077)
- Testing
- Sat75, Sat50
- Where
- United States
- Volunteers
- 700 people
- Sponsor
- University of Texas Southwestern Medical Center
Remote Ischemic Preconditioning
Effects of Remote Ischemic Preconditioning During Free Flap Reconstruction
Remote ischemic preconditioning (RIPC) has been revealed organ-protective effect in many previous clinical settings including coronary intervention or cardiovascular surgery.
- Trial name
- NCT03474952
- Testing
- remote ischemic preconditioning (RIPC)
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Seoul National University Hospital
Very Low Birth Weight Infant
Olfactory Stimulation for Very Low Birth Weight Infants
This is a RCT study examining whether odor administration to mothers of very low birth weight infants promotes stabilization of vital signs compared with common nursing care.
- Trial name
- NCT05406804
- Testing
- Olfactory stimulation, Routine nursing care
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Children's Hospital of Fudan University
Neonatal Disease, Altitude Hypoxia
Reference Interval for SPO2 in Neonates at High Altitudes During First 2 Hours and Umbilical Artery Blood Gas
Pulse oximetry offers real time and non-invasive estimation of arterial oxygen saturation in a cost-effective way, and has become a critical tool in guiding the usage of supplemental oxygen in sick newborns.
- Trial name
- NCT05468515
- Testing
- pulse oxygen saturation
- Where
- China
- Volunteers
- 956 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
Oxygen Saturation, Heart Rate
Effects of Alternate Nostril Breathing Versus Diaphragmatic Breathing on Oxygen Saturation and Heart-rate Variability in Post Percutaneous Coronary Intervention Patients
This study is a two-arm randomized parallel group trial designed to compare the effects of alternate nostril breathing vs diaphragmatic breathing on oxygen saturation and Heart-rate variability in hemodynamically stable post-PCI…
- Trial name
- NCT07867457
- Testing
- Alternate Nostril Breathing, Diaphragmatic breathing
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- Foundation University Islamabad
Hypotension, Poor Peripheral Perfusion
Effect of Vasopressin on Tissue Oxygen Saturation in Cardiac Surgery Patients During Cardiopulmonary Bypass
The objective of this research is to compare the effect of a low dose Vasopressin infusion or placebo during cardiopulmonary bypass on vasopressor requirements, hemodynamics and tissue oxygen saturation and its recovery using…
- Trial name
- NCT01532505
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Mohamed Ismail
Oxygen Saturation
Comparison of Volatile Anesthetics on Cerebral Oxygenation During Controlled Hypotension
Controlled hypotension is a preferred method for reducing surgical bleeding during septoplasty operations however, the level of hypotension and bradycardia should not disrupt cerebral oxygenation.
- Trial name
- NCT02834845
- Testing
- Sevoflurane, Desflurane
- Where
- Turkey (Türkiye)
- Volunteers
- 95 people
- Sponsor
- Ufuk University
Dyspnea, Respiratory Rate
Evaluating the Effectiveness of Incentive Spirometry
Post-operative pulmonary complications (PPCs) have a major impact on patients and healthcare expenses. The goal of perioperative respiratory therapy is to improve airway clearance, increase lung volume, and mitigate atelectasis.
- Conditions
- Dyspnea, Respiratory Rate, Oxygen Saturation, Oxygen Requirements
- Trial name
- NCT02952027
- Testing
- Use-recording, patient-reminder alarm for incentive spirometry
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Lifespan
Hypotension
Clinical Validation of Vital-PICASO for Predicting Hypotension Within 24 Hours in General Ward Inpatients
This retrospective study evaluated the clinical performance of Vital-PICASO, an artificial intelligence-based biological signal analysis software designed to predict the risk of hypotension within 24 hours using vital-sign data…
- Trial name
- NCT07742930
- Where
- South Korea
- Volunteers
- 648 people
- Sponsor
- Huinno AIM
Cerebral Oxygen Saturation,MCA Velocity,Intraoperative Neurological Symptoms During Carotid Endarterectomy
Middle Cerebral Artery Velocity and Oxygen Saturation of the Brain During Carotid Endarterectomy
The primary endpoint of our study is to determine whether neurological symptoms (aphasia, paresis, loss of consciousness, numbness) occur after clamping the internal carotid artery, and if so, changes showed by transcranial…
- Trial name
- NCT02665104
- Testing
- transcranial Doppler (TCD) and INVOS monitor
- Where
- 2 sites in Hungary
- Volunteers
- 100 people
- Sponsor
- University of Debrecen
Rotator Cuff Tear Arthropathy
Vasopressin to Prevent Hypotension During Beach Chair Surgery
Patients undergoing surgery in beach chair position (BCP) are at risk for cerebral ischaemia. The impacts of arginine vasopressin (AVP) on haemodynamics and cerebral oxygenation are evaluated during surgery in BCP.
- Trial name
- NCT01687894
- Testing
- Vasopressins, propofol, sevoflurane
- Where
- South Korea
- Volunteers
- 74 people
- Sponsor
- Chonnam National University Hospital