Clinical trials: Oxygen Toxicity, open to volunteers
Oxygen Toxicity, COPD Bronchitis
Comparison of Several Oxygenation Targets With Different Oxygen Interfaces - Impact on Oxygen Flow Rates
Oxygen therapy is at the heart of the healthcare system. Oxygen flow rates depend on a number of confounding factors confounding factors (target used, skin pigmentation, pulse oximeter used, etc.) The investigators have recently…
- Conditions
- Oxygen Toxicity, COPD Bronchitis, Respiratory Failure
- Trial name
- Interfaces (NCT06646991)
- Testing
- Nasal canula - up to 6 liters per minute, Nasal canula - up to 15 liters per minute, Open oxygen mask
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Laval University
Oxygen Toxicity, Oxidative Stress
Effect of Hydrogen Gas on Hyperbaric Oxygen Toxicity
The goal of this trial is to investigate whether adding a small fraction of hydrogen gas to an oxygen-enriched breathing mixture can reduce pulmonary oxygen toxicity (POT) in healthy and active divers from the Swedish Armed…
- Conditions
- Oxygen Toxicity, Oxidative Stress, Hyperoxia, Hyperbaric Oxygen
- Trial name
- NCT07263399
- Testing
- Inhaled Hydrogen-Enriched Oxygen Gas, Inhaled Nitrogen-Enriched Oxygen Gas
- Where
- 2 sites in Sweden
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Blekinge Institute of Technology
Oxygen Toxicity, Hypercapnia
Oxygen Toxicity: Mechanisms in Humans
The goal of this clinical trial is to learn about the mechanisms of oxygen toxicity in scuba divers. The main questions it aims to answer are: How does the training of respiratory muscles affect oxygen toxicity? How do…
- Conditions
- Oxygen Toxicity, Hypercapnia, Seizures
- Trial name
- NCT05761756
- Testing
- Sleep Deprivation, Caffeine, Methylphenidate
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Duke University
Oxygen Toxicity, Respiratory Failure
Comparison of Two Oxygenation Targets With Two Different Oximeters - Impact on Oxygen Flow Rates and Oxygenation
The investigators recently evaluated 4 different oximeters among the most commonly used with arterial catheter in place and compared SpO2 with SaO2 obtained on arterial gas.
- Trial name
- Oxygap pong (NCT05590130)
- Testing
- Manual Oxygen titration with Philips oximeter (SpO2 target 90%), Manual oxygen titration with Nonin oximeter (SpO2 target 90%), Manual Oxygen titration with Philips oximeter (SpO2 target 94%)
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Laval University