Clinical trials: Oxygen Utilization
Pre-Eclampsia
Utilization of Somatic Tissue Oxygen Saturation Monitoring in Pregnant Women
The purpose of this study is to compare 3 methods of assessing endothelial function in healthy female volunteers and pregnant women with and without pregnancy induced hypertension.
- Trial name
- NCT03196141
- Testing
- StO2 and EndoPAT
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Yale University
Subarachnoid Hemorrhage, Cerebral Vasospasm
Use of Brain Oxygen Tension Level and Cleaved-tau Protein to Detect Vasospasm After SAH
The purpose of this study is to investigate if brain oxygen levels, levels of a specific protein in the cerebrospinal fluid and blood (Cleaved-tau protein), and brain blood flow can predict spasm of brain blood vessels after…
- Trial name
- NCT00582868
- Testing
- Licox Brain Oxygen Monitor, CSF, Whole blood
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Wisconsin, Madison
Cardiac Disease, Risk Factor, Cardiovascular
Virtual Reality Based-therapy Applied to Physical Therapy in Cardiology.
The aim of this study is to investigate engagement, motivation, and the barriers to adherence of virtual reality based therapy (VRBT) in patients with cardiac diseases and risk factors to the development of cardiac diseases.
- Trial name
- NCT03377582
- Testing
- Exercise
- Where
- Brazil
- Volunteers
- 68 people
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
COVID-19, Heart Rate
Effect of Mask Use on Hemodynamic Responses During Exertion
The use of masks is a necessity due to the current pandemic conditions. The aim of the study is to examine the effects of the use of masks during effort on dyspnea and fatigue with hemodynamic parameters.
- Conditions
- COVID-19, Heart Rate, Blood Pressure, Exercise Test
- Trial name
- NCT05401331
- Testing
- Treadmilll, mask
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Pulmonary Disease, Chronic Obstructive, Hypercapnia
Sleep and Daytime Use of Humidified Nasal High-flow Oxygen in COPD Outpatients
Humidified Nasal High-flow with Oxygen (HNHF-O2) therapy has been reported to have acute beneficial effects in patients with hypoxemic respiratory failure who have been hospitalized.
- Conditions
- Pulmonary Disease, Chronic Obstructive, Hypercapnia, Hypoxia
- Trial name
- NCT03221387
- Testing
- Humidified nasal high flow with oxygen
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Temple University
Bronchiolitis
High Flow Nasal Cannula Use in Infants With Bronchiolitis
Infants with viral bronchiolitis are currently treated with oxygen therapy if oxygen saturation is low. In earlier observational clinical studies, the use of high flow nasal cannulae therapy in infants with bronchiolitis has been…
- Trial name
- NCT02737280
- Testing
- Airvo (TM, Fisher & Paykel Healthcare) - High flow oxygen therapy, MedKit Finland - Usual oxygen therapy
- Where
- 4 sites in Finland
- Volunteers
- 18 people
- Sponsor
- University of Oulu
Prematurity, Apnea
Caffeine to Reduce Mechanical Ventilation in Preterm Infants
Most premature infants require mechanical ventilation for prolonged periods of time and a significant proportion of them develop Bronchopulmonary Dysplasia (BPD).
- Conditions
- Prematurity, Apnea, Respiratory Failure
- Trial name
- NCT01751724
- Testing
- Caffeine citrate, Normal saline
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- University of Miami
COVID-19
Compassionate Use of Hyperbaric Oxygen Therapy
This is an observational patient registry of COVID-19 patients treated with HBOT.
- Trial name
- NCT04386265
- Where
- 11 sites in United States, Poland
- Volunteers
- 100 people
- Sponsor
- SerenaGroup, Inc.
Pneumonia in Children, Measurement of Peripheral Oxygen Saturation
Development of a Robust and Reliable Pulse Oximeter for Children With Pneumonia in Low-income Countries
This study is to test the usability of a new pulse oximeter probe designed for children 0-5 years.
- Trial name
- NCT02941237
- Testing
- Pulse oximeter
- Where
- 3 sites in Bangladesh, Malawi and 1 more
- Volunteers
- 572 people, healthy volunteers welcome
- Sponsor
- The Lifebox Foundation
Oxygen Utilization, Oxygen Kinetics
Mushroom Blend on Oxygen Kinetics
Purpose: To determine the acute effects of a mushroom blend vs. placebo on oxygen kinetics, aerobic power and time to fatigue in healthy adults.
- Trial name
- NCT02075892
- Testing
- Mushroom Blend
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Premature Infant, Respiratory Distress Syndrome in Premature Infant
30% or 60% Oxygen at Birth to Improve Neurodevelopmental Outcomes in Very Low Birthweight Infants
Preterm birth, or birth before 37 weeks' gestation, is increasingly common, occurring in 8 percent of pregnancies in Canada. Preterm birth is associated with many health complications, particularly when the birth happens before…
- Conditions
- Premature Infant, Respiratory Distress Syndrome in Premature Infant, Neurodevelopmental Outcome
- Trial name
- HiLo (NCT03825835)
- Testing
- 30% oxygen group, 60% oxygen group
- Where
- 14 sites in Canada, Ireland
- Volunteers
- 1,203 people
- Sponsor
- University of Alberta
Traumatic Brain Injury, Hemorrhagic Shock
The Use of Tissue Oxygen Monitoring in Critically Injured Patients
It is anticipated that the use of tissue oxygen monitoring to measure brain tissue oxygen and deltoid muscle oxygen will provide more precise information about focal brain ischemia and systemic hypoperfusion than current…
- Conditions
- Traumatic Brain Injury, Hemorrhagic Shock, Trauma
- Trial name
- NCT00328341
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- University of California, San Francisco
Chronic Respiratory Failure With Hypoxia, Chronic Obstructive Pulmonary Disease
Objective Evaluation of the Number of Use Hour of Oxygen Therapy in Patients Receiving Supplemental Oxygen
The aim of this study is to measure the actual use time in patients receiving supplemental oxygen using a new easy-to-use electronic remote monitoring device (TeleOx™)
- Trial name
- MONOX (NCT04204031)
- Testing
- Presentation of the adherence record
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- Haute Ecole de Santé Vaud
Cardiac; Arteriosclerosis, Aortic Valve Disease
The Association Between Delivered Oxygen and Cerebral Impact During the Use of Cardiopulmonary Bypass.
Investigating the connection between delivered oxygen index and cerebral impact with COx (cerebral oximetry index) och cerebral injury markers during the routine use of cardiopulmonary bypass.
- Trial name
- NCT05620875
- Testing
- Cerebral injury markers, Cerebral oximetry index
- Where
- Sweden
- Volunteers
- 106 people
- Sponsor
- Uppsala University
Opioid Use Disorder
Hyperbaric Oxygen Treatment (HBOT) During Methadone Tapering
The aims of this study are to 1) explore the efficacy of hyperbaric oxygen therapy (HBOT) applied at two different pressures compared to sham treatment in relieving signs and symptoms (both physical and psychological) of opioid…
- Trial name
- NCT05924022
- Testing
- Hyperbaric Oxygen Treatment Full, Hyperbaric Oxygen Treatment Partial Pressure
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Washington State University
Aortic Stenosis, Sedation Complication
High Flow Nasal Oxygen Cannula in Transcatheter Aortic Valve Replacement: Complications and Biomarkers
Background Transcatheter aortic valve replacement is a risky procedure, performed in patients that can also be considered at risk of developing complications.
- Trial name
- HIGH-OXY-TAVR (NCT05958537)
- Testing
- High flow nasal oxygen
- Where
- Spain
- Volunteers
- 132 people
- Sponsor
- Hospital Clinic of Barcelona
Obesity, Obstructive Sleep Apnea (Moderate to Severe)
Heated Humidified High Flow Nasal Cannula Oxygen in Obstructive Sleep Apnea in Adolescents
The research study is being done to test heated humidified high-flow air (HHF), as a treatment for OSA.
- Conditions
- Obesity, Obstructive Sleep Apnea (Moderate to Severe), Central Sleep Apnea
- Trial name
- NCT05354401
- Testing
- HHF
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- The Hospital for Sick Children
Endometriosis
Use of Antioxidant in Endometriotic Women to Improve Intracytoplasmic Sperm Injection (ICSI)
ROS plays an essential role in the pathogenesis of many reproductive processes. High follicular fluid ROS levels are associated with negative IVF outcomes.
- Trial name
- ROS (NCT02058212)
- Testing
- ascorbate 1000mg, vitamin E 400, zinc and selenium
- Where
- 3 sites in Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Obesity & Overweight, Energy Expenditure
Metabolic and Nutritional Responses to Acute High-intensity Interval Exercise Performed Under Hypoxic vs. Normoxic Conditions at Matched External Workload in Adults With Overweight and Obesity.
Obesity management involves lifestyle and dietary measures that include appropriate nutrition and increased physical activity (PA).
- Conditions
- Obesity & Overweight, Energy Expenditure, Substrate Oxidation
- Trial name
- HYPOXHIIT (NCT07814599)
- Testing
- HIIE - Normoxia, HIIE - Hypoxia
- Where
- France
- Volunteers
- 18 people
- Sponsor
- Laboratoire des Adaptations Métaboliques à l'Exercice en conditions Physiologiques et Pathologiques
Cardiac Diseases
MEOPA-coupled Hypnosis Versus MEOPA-standard Care in Transesophageal Echocardiography
The primary purpose is to evaluate the impact of hypnosis coupled with MEOPA (Equimolar Mix-ture of Nitrogen Protoxide and Oxygen) on patient comfort when performing transoesophageal echocardiographies.
- Trial name
- HYPNETO (NCT04398017)
- Testing
- Transesophageal echography
- Where
- France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Strasbourg, France