Clinical trials: Oxytocin
Adverse Reaction to Oxytocin
Continued Versus Discontinued Oxytocin Stimulation of Labour
Background: The proposed study will investigate the effect of Syntocinon® (synthetic oxytocin) to induce labour. The hypothesis to be studied is that once the active phase of labour has commenced, Syntocinon® can be discontinued…
- Trial name
- CONDISOX (NCT02553226)
- Testing
- Oxytocin
- Where
- 10 sites in Denmark, Netherlands
- Volunteers
- 1,200 people
- Sponsor
- University of Aarhus
Oxytocin Deficiency, Postpartum Depression
The Relationship Between Oxytocin Level and Postpartum Depression
There are studies in the literature that associate oxytocin level with postpartum depression. This study was carried out to investigate the relationship between oxytocin levels measured during pregnancy and postpartum depression…
- Conditions
- Oxytocin Deficiency, Postpartum Depression, Prenatal Stress
- Trial name
- NCT04427410
- Testing
- Salivary test
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Oxytocin, Estrogen
Dissecting the Role of Estradiol in Mediating Gender-specific Anxiolytic and Prosocial Effects of Oxytocin
The study aims to examine a behavioral and neural framework for understanding the sex-specific effects of the neuropeptide oxytocin (OXT).
- Conditions
- Oxytocin, Estrogen, Fear Extinction, Emotion Processing
- Trial name
- ESMory (NCT04330677)
- Testing
- Oxytocin nasal spray, Estrogen Gel
- Where
- Germany
- Volunteers
- 487 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bonn
Oxytocin
Effects of Oxytocin on Cognitive and Reactive Fear
The study examines the (sub)regional specificity of anxiolytic oxytocin (OXT) effects on emotional face processing and reactive and cognitive fear.
- Trial name
- RAGE (NCT04292444)
- Testing
- Oxytocin nasal spray
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bonn
Schizophrenia, Oxytocin
Adult Study Oxytocin - Behavioral
In this study, investigators will examine the behavioral effects and neurophysiological mechanisms of the pro-social neuropeptide oxytocin in patients with recent-onset schizophrenia and other psychotic disorders.
- Conditions
- Schizophrenia, Oxytocin, Social Cognition, Psychotic Disorders
- Trial name
- ASO-Behavioral (NCT02567032)
- Testing
- Oxytocin, Saline Nasal Spray
- Where
- 2 sites in United States
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Oxytocin, Hemodynamic Monitoring
Effects of Oxytocin on Hemodynamics in Patients Undergoing Laparoscopic Myomectomy
This project will study the effect of oxytocin on hemodynamics in patients undergoing laparoscopic myomectomy, and how to prevent and manage such hemodynamic changes effectively.It provides a reference for the rational use of…
- Conditions
- Oxytocin, Hemodynamic Monitoring, Laparoscopic Surgery
- Trial name
- NCT04109339
- Testing
- Oxytocin
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Yangzhou University
Cesarean Section Complications, Oxytocin Adverse Reaction
Comparaison of 3 Protocols of Ocytocin Administration in C Section
This study aimed to compare 3 doses of ocytocin in bolus injection and contnious perfusion during C section. these doses determined by: high, intermediate and low doses, were administred to parturients during elective or urgent C…
- Trial name
- NCT04046510
- Testing
- Ocytocin
- Where
- Tunisia
- Volunteers
- 180 people
- Sponsor
- Mongi Slim Hospital
Oxytocin
Influence of Oxytocin on Resting State Neurophysiological Measures
In this study, the investigators will explore the influence of oxytocin administration on several neurophysiological responses (EEG, skin conductance and heart rate) during rest.
- Trial name
- NCT03255148
- Testing
- Oxytocin
- Where
- Belgium
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Oxytocin
Influence of Oxytocin on Neurophysiological Responses to Live Faces
Previous research has indicated that direct eye gaze compared to averted gaze, elicits a higher skin conductance response (SCR), and a more pronounced left frontal cortex activity than right frontal cortex activity (resulting in…
- Trial name
- NCT03272321
- Testing
- Oxytocin
- Where
- Belgium
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Schizophrenia, Oxytocin
Adult Study Oxytocin - fMRI
In this study, investigators will examine the behavioral effects and neurophysiological mechanisms of the pro-social neuropeptide oxytocin in patients with recent-onset schizophrenia.
- Conditions
- Schizophrenia, Oxytocin, Social Cognition, Functional Magnetic Resonance Imaging (fMRI)
- Trial name
- ASO-fMRI (NCT02566356)
- Testing
- Oxytocin, Saline Nasal Spray
- Where
- 2 sites in United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Schizophrenia, Oxytocin
Oxytocin MEG Study
The specific aim of this proposal is to investigate the neurophysiological mechanisms of oxytocin's (OT) prosocial effects in patients with schizophrenia and healthy subjects using magnetoencephalography.
- Conditions
- Schizophrenia, Oxytocin, Magnetoencephalography (MEG), Social Cognition
- Trial name
- MEG (NCT02568709)
- Testing
- Oxytocin, Saline Nasal Spray
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Schizophrenia, Oxytocin
Adult Oxytocin Study
In this study, investigators will examine the behavioral effects and neurophysiological mechanisms of the pro-social neuropeptide oxytocin in patients with recent-onset schizophrenia.
- Conditions
- Schizophrenia, Oxytocin, Social Cognition
- Trial name
- OT (NCT02577575)
- Testing
- Oxytocin, Saline Nasal Spray
- Where
- 2 sites in United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Oxytocin, Lorazepam, Anti-Anxiety Agents, Physiological Effects of Drugs
Effects of Oxytocin and Lorazepam on Fear-related Intra-amygdalar Activity
High-potency benzodiazepines have strong anxiolytic effects accompanied by significant adverse effects including impaired cognitive function, drowsiness, dizziness and impaired motoric abilities.
- Trial name
- NCT03829839
- Testing
- Oxytocin, Lorazepam 1 mg
- Where
- Germany
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bonn
Oxytocin Group, L-DOPA Group
Oxytocin and Dopamine's Effect on Vicarious Optimism
To investigate the effect of intranasal Oxytocin and L-DOPA's effect on vicarious optimism.
- Conditions
- Oxytocin Group, L-DOPA Group, Placebo Group
- Trial name
- NCT03891095
- Testing
- Oxytocin, L-DOPA
- Where
- China
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Beijing Normal University
Oxytocin Effect on Memory Performance During Phase 1, Oxytocin Effect on Memory Performance During Phase 2
Can Oxytocin Enhance the Placebo Effect?
The current study aimed to investigate whether oxytocin (OXT) had effect on placebo effect.
- Conditions
- Oxytocin Effect on Memory Performance During Phase 1, Oxytocin Effect on Memory Performance During Phase 2, Oxytocin Effect on Memory Performance During Phase 3, Oxytocin Effect on Memory Performance During Phase 4
- Trial name
- NCT02745522
- Testing
- Oxytocin
- Where
- China
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Oxytocin and Abdominal Myomectomy
Oxytocin Infusion and Abdominal Myomectomy
Objective:To compare oxytocin infusion with control, in patients undergoing abdominal myomectomy in terms of mean blood loss. Design: Single blinded randomized control trial Setting: Obstetrics and Gynecology Department, Military…
- Trial name
- NCT03702946
- Testing
- oxytocin in abdominal myomectomy
- Where
- 2 sites in Pakistan
- Volunteers
- 60 people
- Sponsor
- Armed Forces Hospital, Pakistan
Impact of Oxytocin on Social Learning
Modulation of Reinforcement Learning
This study aims to examine the modulation of neuronal and behavioural parameters of social reinforcement learning.
- Trial name
- NCT01712464
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- RWTH Aachen University
Oxytocin, Pregnancy
Non-Invasive, Highly Specific Detection of Oxytocin in Biological Fluids
This study will aid in the development of a research instrument for rapid and highly sensitive detection of perinatal salivary oxytocin, by non-invasive means.
- Trial name
- NCT03140709
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Stanford University
Complications; Cesarean Section, Adverse Reaction to Oxytocin
Outcomes After the Implementation of a New Oxytocin Protocol
The proposed study is a prospective, randomized, active control, open label study. One hundred sixty subjects undergoing elective cesarean section will be randomly assigned to one of two groups (n = 80 per group): the oxytocin…
- Trial name
- NCT02722356
- Testing
- Oxytocin
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- C.R.Darnall Army Medical Center
Intemittant, Continue, Oxytocin
Continuous Versus Intermittent Oxytocin for Induction of Labor: A Randomized Study
This study evaluates continuous oxytocin versus intermittent oxytocin for induction of labor at term. Half of participants will be taken continuous oxytocin, while the other half will be taken intermittent oxytocin.
- Trial name
- NCT02859571
- Testing
- Oxytocin
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Zeynep Kamil Maternity and Pediatric Research and Training Hospital