Clinical trials: Ozone
Low Back Pain, Posterior Compartment
The Efficacy of Ultrasound-guided Ozone Injection in the Treatment of Patients With Chronic Low Back Pain
Low back pain is a common disorder that every individual in the society is likely to meet throughout his/her life. Low back pain lasting longer than 12 weeks is defined as chronic low back pain and causes serious disability in…
- Trial name
- NCT05586633
- Testing
- deep paravertebral periforaminal ozone injeciton, transforaminal steroid injeciton
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Lumbar Radiculopathy, Lumbar Disc Herniation
Randomized Evaluation of Lumbar Injection Effectiveness and Function
The goal of this clinical trial is to learn whether the Triojection® System is safe and effective for treating symptomatic lumbar radiculopathy (leg pain caused by nerve irritation or compression) resulting from a contained…
- Conditions
- Lumbar Radiculopathy, Lumbar Disc Herniation, Contained Herniated Lumbar Disc
- Trial name
- RELIEF (NCT07856810)
- Testing
- Triojection® System, Selective Nerve Root Block (SNRB)
- Volunteers
- 300 people
- Sponsor
- SpinaFX Medical Inc.
Air Pollution Exposure, Oxidative Stress
Savannah Environmental Nutrition Study (SENS): Nutrition Intervention to Reduce Air Pollution-Related Airway Inflammation and Oxidative Stress
This pilot clinical trial will evaluate the feasibility and potential health effects of a nutrition-based intervention among adults living in communities affected by air pollution near the Port of Savannah, Georgia.
- Conditions
- Air Pollution Exposure, Oxidative Stress, Airway Inflammation
- Trial name
- NCT07797413
- Testing
- Antioxidant- and Nutrient-Rich Food-Based Nutrition Intervention
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Georgia Southern University
Subjective Discomfort, General Mucosal Irritation
Controlled Human Exposure to Indoor Air, Dust and Ozone
The aim of the study is to provide information which may help to improve the quality of the life of persons exposed to indoor environments in Danish dwellings.
- Conditions
- Subjective Discomfort, General Mucosal Irritation, Acute Changes in Respiratory Outcomes, Acute Changes in Cardiovascular Outcomes
- Trial name
- XDOZ (NCT02017782)
- Testing
- Dust, Ozone, Dust and Ozone
- Where
- Denmark
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Orofacial Pain, Temporomandibular Joint Disorders
Ozone Therapy for Masticatory Muscle Pain (OTMMP)
This study investigates the efficacy of bio-oxidative ozone application in the treatment of TMD of muscular origin.
- Trial name
- OTMMP (NCT02997410)
- Testing
- Ozone, Dental treatment with occlusal splint
- Volunteers
- 60 people
- Sponsor
- Istanbul University
COVID, SARS-CoV 2
Oxygen-Ozone as Adjuvant Treatment in Early Control of COVID-19 Progression and Modulation of the Gut Microbial Flora
Italy was the first European country affected by a severe outbreak of the Severe Acute Respiratory Syndrome - CoronaVirus-2 (SARS-CoV-2) epidemic emerged from Wuhan region (China), with a high morbidity and mortality associated…
- Conditions
- COVID, SARS-CoV 2, Pneumonia, Viral, Coronavirus Infection
- Trial name
- PROBIOZOVID (NCT04366089)
- Testing
- Oxygen-ozone therapy, probiotic supplementation and Standard of care, SivoMixx (200 billion), Azithromycin
- Where
- Italy
- Volunteers
- 152 people
- Sponsor
- Roberto Poscia MD, PhD
Ischemic Heart Disease
Ozone Therapy in Refractory Ischemic Heart Disease.
The main objective of this clinical trial is to evaluate the effectiveness and cost-effectiveness of adding ozone therapy to standard management of patients with advanced ischemic heart disease refractory to medical and surgical…
- Trial name
- O3Cardio (NCT03660657)
- Testing
- Ozone, Oxygen
- Where
- Spain
- Volunteers
- 1 people
- Sponsor
- Bernardino Clavo, MD, PhD
Endometriosis, Ozone Therapy
Ozone Therapy for Women With Endometriosis
To evaluate the action of ozone therapy as an adjuvant treatment in patients with endometriosis. Secondary Objective: To evaluate the efficacy of ozone therapy for pelvic analgesia in women with endometriosis; To compare the…
- Conditions
- Endometriosis, Ozone Therapy, Thermography
- Trial name
- NCT07035522
- Testing
- Ozone therapy
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Universidade Federal do Paraná
Chronic Obstructive Pulmonary Disease (COPD)
Study to Evaluate the Effect of Bimosiamose on Ozone Induced Sputum Neutrophilia
The purpose of this study is to evaluate the safety, tolerability and efficacy of repeated inhalative doses of Bimosiamose on ozone induced sputum neutrophilia in healthy subjects.
- Trial name
- NCT00962481
- Testing
- Bimosiamose
- Where
- Germany
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Revotar Biopharmaceuticals AG
Intraarticular, Ozone
Effect of Intraarticular Ozone, Prolotherapy or Dexmedetomidine in Pain Limitation in Knee Osteoarthritis
This study aimed to compare intraarticular ozone injection, prolotherapy, or dexmedetomidine effectiveness in knee osteoarthritis patients.
- Conditions
- Intraarticular, Ozone, Prolotherapy, Dexmedetomidine
- Trial name
- NCT06909305
- Testing
- Ozone, Dextrose prolotherapy, Dexmedetomidine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Corneal Endothelial Cell Loss, Ozone Therapy
Effect of Systemic Ozone Therapy on Corneal Endothelium
This study evaluates the safety of systemic ozone therapy on the corneal endothelium, a vital non-renewable tissue that maintains corneal transparency.
- Trial name
- OZON-CORNEA (NCT07718100)
- Testing
- Systemic Ozone Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Knee Osteoarthritis
Effects of Platelet-Rich Plasma and Ozone Therapy in Knee Osteoarthritis
Knee osteoarthritis can frequently occur with advancing age. In cases of pain that persists despite hot/cold applications, drug therapy and exercise, intra-articular injections are considered.
- Trial name
- NCT06631456
- Testing
- PRP injection, Ozone therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Chemotherapy-induced Nausea and Vomiting
Low Dose Olanzapine to the Prophylaxis of Nausea and Vomiting Induced by Chemotherapy in Children and Adolescents
Chemotherapy-induced nausea and vomiting continues to be a significant problem in children and adolescents. Standard antiemetic therapy, including a 5-HT3 antagonist, aprepitant, and a corticosteroid, achieves complete control in…
- Trial name
- OZONE-V (NCT05346731)
- Testing
- Ondansetron, Dexamethasone, Aprepitant
- Where
- Russia
- Volunteers
- 210 people
- Sponsor
- Federal Research Institute of Pediatric Hematology, Oncology and Immunology
Myofascial Pain Syndrome (Upper Trapezius)
Ultrasound-Guided Dry Needling, Lidocaine Injection, and Oxygen-Ozone Therapy for Myofascial Pain Syndrome
Prospective, assessor-blinded, randomized controlled trial comparing ultrasound-guided dry needling, lidocaine injection, and oxygen-ozone injection in patients with myofascial pain syndrome (MPS) of the upper trapezius muscle.
- Trial name
- USDLO-MPS (NCT07738783)
- Testing
- Dru Needling, Lidocaine Injection (1%, 2 mL), Oxygen-Ozone Injection (10 μg/mL, 5 mL)
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Derince Training and Research Hospital
Environmental Exposure, Ozone
Lung Mucus Hypersecretion and NQO1
The research plan proposes translational studies in relevant animal models and human subjects in order to identify host (genetic) susceptibility factors that confer vulnerability to the prototypal air pollutant, ozone.
- Conditions
- Environmental Exposure, Ozone, Air Pollution, Genetic Susceptibility
- Trial name
- NCT00729352
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Periodontitis
Effects of Ozone Therapy as an Adjunct to Periodontal Treatment
This randomized, placebo controlled, split-mouth clinical study trial evaluates the effects of Ozone therapy on clinical and biochemical parameters. Total of 20 participants completed the study .
- Trial name
- NCT03652558
- Testing
- Ozone application with the Ozonytron XL device
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University