Clinical trials: Ozone Therapy
Hypertonia
Grand Autohemo-Therapy With Oxygen-ozone on Patients With Hypertonia
The objective of this clinical study is to evaluate the influence of the Great autohemotherapy with oxygen-ozone (hyperbaric ozone therapy ) to describe the cardiovascular system in patients with resistant hypertension.
- Trial name
- HAB (NCT01902602)
- Where
- Germany
- Volunteers
- 19 people
- Sponsor
- Herrmann Apparatebau GmbH
COVID-19 Pneumonia
Ozone Auto-hemotherapy for COVID-19 Pneumonia
This is a multicenter, randomized, controlled, open-label clinical trial testing the use of ozone auto-hemotherapy in hospitalized patients with Covid-19 pneumonia.
- Trial name
- COVID-OZONE (NCT04370223)
- Testing
- Ozone auto-hemotherapy
- Where
- 10 sites in Spain
- Volunteers
- 208 people
- Sponsor
- Institut d'Investigació Biomèdica de Girona Dr. Josep Trueta
Epicondylitis, Lateral
Comparison of ESWT and Ultrasound-Guided Ozone Injection in Lateral Epicondylitis
Lateral epicondylitis is a common and often debilitating condition characterized by pain over the lateral aspect of the elbow. Although many patients respond to standard conservative treatments, a subset develops a chronic and…
- Trial name
- NCT07427368
- Testing
- ESWT Device, ozone injection
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Ankara City Hospital Bilkent
Interstitial Cystitis, Bladder Pain Syndrome
Intravesical Ozone Therapy for Interstitial Cystitis/Bladder Pain Syndrome
This randomized, double-blind, placebo-controlled trial evaluated the efficacy and safety of intravesical ozone therapy in 60 patients with interstitial cystitis (IC).
- Trial name
- NCT06863220
- Testing
- Intravesical Ozone Therapy, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Medipol University
Dental Caries, Early Caries Lesion
Effect of Ozone Therapy on Remineralization of Initial Caries Lesions in Children
Initial caries lesions can be managed using non-invasive treatment approaches that promote remineralization and prevent lesion progression.
- Trial name
- OZONE-CARIES (NCT07671651)
- Testing
- Ozone Therapy, other
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Neslihan Atmaca
Periodontitis, Lasers
The Effect of Adjunctive Therapies in Regenerative Treatment of Stage III Grade C Periodontitis
Anti-infective procedures play a very important role in the success of regenerative surgical treatment of aggressive periodontitis, Grade C periodontitis, which shows the newly named molar-incisor pattern according to the 2017…
- Conditions
- Periodontitis, Lasers, Ozone, Wound Healing
- Trial name
- NCT05447026
- Testing
- Control group, Antimicrobial photodynamic therapy (aPDT) group, LED photobiomodulation group
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Gazi University
Chronic Hepatitis B
A Control Study to Evaluate The Efficacy And Safety of Ozone-therapy in Chronic Hepatitis B
The purpose of this study is to investigate the efficacy and safety of medical ozone in treatment of chronic hepatitis B patients.
- Trial name
- NCT01887275
- Testing
- medical ozone therapy with humares, conventional interferon-α
- Where
- China
- Volunteers
- 439 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Keratitis
Ozone-based Eye Drops as Adjuvant Therapy in Microbial Keratitis
To compare the therapeutic effect of ozone-based eye drops as an adjuvant therapy to that of the conventional topical antimicrobial agents in patients with microbial keratitis .
- Trial name
- NCT05689996
- Testing
- Ozone-Based Agent
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assiut University
Chronic Periodontitis
Effects of Ozone Therapy on Clinical Parameters and Inflammatory Cytokines in Chronic Periodontitis Patients
The objective of this study is to evaluate of ozone therapy on both clinical and biochemical effects in periodontally patients.
- Trial name
- NCT03874390
- Testing
- ozone
- Volunteers
- 50 people
- Sponsor
- Ataturk University
Back Pain
Study on the Effects of Oxygen-ozone Therapy on Back Pain in Subjects Aged 65 or Older
This study aims to evaluate the efficacy of the oxygen-ozone therapy in the treatment of back pain in subjects aged 65 or older.
- Trial name
- O2-O3 (NCT01709058)
- Testing
- Intramuscular/paravertebral injections of Oxygen-Ozone, Simulated intramuscular/paravertebral injections
- Where
- Italy
- Volunteers
- 130 people
- Sponsor
- Istituto Nazionale di Ricovero e Cura per Anziani
COVID-19 Pneumonia
Ozone Therapy and Coronavirus Disease of 2019 (COVID-19) Pneumonia
The objective is to determine whether the use of ozone autohemotherapy is associated with a decrease in time to clinical improvement
- Trial name
- NCT04444531
- Where
- Spain
- Volunteers
- 18 people
- Sponsor
- Institut d'Investigació Biomèdica de Girona Dr. Josep Trueta
Pregnancy Gingivitis, Ozone
Ozone Therapy for the Home Oral Hygiene of the Pregnant Woman.
The aim of the present study is analyzing the effect of an domestic ozonated water delivering device on the oral health status of pregnant women.
- Trial name
- NCT04140643
- Testing
- Ozonated water delivering device effects on the oral health of pregnant women, Oral hygiene instructions
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Oral Mucositis, Head and Neck Neoplasms
Laser vs Ozone Therapy for Oral Mucositis in Cancer Patients
This randomized clinical trial aims to compare the efficacy of laser therapy and ozone therapy in the treatment of oral mucositis in adult cancer patients undergoing chemotherapy or radiotherapy, particularly those with head and…
- Conditions
- Oral Mucositis, Head and Neck Neoplasms, Hematologic Neoplasms
- Trial name
- LOMUC (NCT07069153)
- Testing
- Laser Therapy, Ozone therapy
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Pavia
Chemotherapy Induced Peripheral Neuropathy (CIPN), Paresthesia
Gut Microbiome Profiles in Patients With Chemotherapy-induced Neuropathy in the RCT OzoParQT (NCT06706544).
Chemotherapy-induced peripheral neuropathy (CIPN) is a common and debilitating side effect of chemotherapy (CT), often requiring dose reductions or treatment interruptions, which can compromise efficacy of the planned CT…
- Conditions
- Chemotherapy Induced Peripheral Neuropathy (CIPN), Paresthesia, Numbness, Tingling
- Trial name
- OzoParQTmicrob (NCT06799351)
- Testing
- Ozone therapy
- Where
- Spain
- Volunteers
- 42 people
- Sponsor
- Bernardino Clavo, MD, PhD
Periodontal Pocket, Periodontitis
Use of Ozone Gel as an Antimicrobial in Treatment of Periodontitis
Periodontitis is an inflammatory disease that destroys tooth-supporting structures through oral bacterial plaque. ozone gel's act as an antimicrobial effect as an adjunct to conventional periodontal therapy (scaling and root…
- Trial name
- NCT05905445
- Testing
- ozone gel
- Where
- Iraq
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Ghufran Falih Hassan
Plantar Fascitis
Comparison of the Efficiency of ESWT and Ozone Injection in Patients With Chronic Plantar Fasciitis
Extracorporeal Shock Wave Therapy (ESWT) is a conservative treatment method that has been widely used in musculoskeletal diseases in recent years.
- Trial name
- NCT06041230
- Testing
- Ozone Generator, Extracorporeal shock wave therapy device
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Ankara City Hospital Bilkent
Osteoarthritis of the Knee
Intraarticular Ozone Therapy for Pain Control in Osteoarthritis of the Knee
The purpose of this study is to determine whether an intraarticular injection of Ozone into the knee joint is an effective therapy for pain control in patients with osteoarthritis of the knee.
- Trial name
- NCT00832312
- Testing
- ozone-oxygen mixture
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Ben-Gurion University of the Negev
Chemotherapy-induced Peripheral Neuropathy, Pain, Neuropathic
Ozone Therapy in Chemotherapy-induced Peripheral Neuropathy: RCT (O3NPIQ)
The main objective of this clinical trial is to evaluate the effectiveness and cost-effectiveness of adding ozone therapy to the clinical management of patients with pain secondary to chemotherapy-induced peripheral neuropathy
- Conditions
- Chemotherapy-induced Peripheral Neuropathy, Pain, Neuropathic, Pain Syndrome
- Trial name
- O3NPIQ (NCT04299893)
- Testing
- Ozone, Oxygen
- Where
- 2 sites in Spain
- Volunteers
- 42 people
- Sponsor
- Bernardino Clavo, MD, PhD
Dental, Implant Osseointegration
Validity of Ozonated Olive Oil Gel Versus Injectable Bone Graft
Many of studies have been performed to improve osseointegration and bone density around implants by modifying the implant by adding bone graft or substitute material that increase success of implant.
- Conditions
- Dental, Implant Osseointegration, Ozone Therapy, Bone Graft
- Trial name
- NCT07368114
- Testing
- Immediate implant placement, β-tricalcium phosphate Injectable Bone Graft, Ozonated olive oil gel
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Suez Canal University
Ischemic Heart Disease
Ozone Therapy in Refractory Ischemic Heart Disease.
The main objective of this clinical trial is to evaluate the effectiveness and cost-effectiveness of adding ozone therapy to standard management of patients with advanced ischemic heart disease refractory to medical and surgical…
- Trial name
- O3Cardio (NCT03660657)
- Testing
- Ozone, Oxygen
- Where
- Spain
- Volunteers
- 1 people
- Sponsor
- Bernardino Clavo, MD, PhD