Clinical trials: PAD - Peripheral Arterial Disease
Peripheral Arterial Disease
Clinical Evaluation of the BlueDop Vascular Expert for Assessing Peripheral Arterial Disease
This is a BlueDop Vascular Expert System (BVE) Post-Market Clinical Follow-Up (PMCF) study. The primary objective of the study is to assess the clinical applicability and diagnostic accuracy of the BVE device in subjects who…
- Trial name
- NCT05073510
- Testing
- BVE
- Where
- 4 sites in Spain
- Volunteers
- 187 people, healthy volunteers welcome
- Sponsor
- BlueDop Medical LTD
Cardiovascular Diseases, Acute Coronary Syndrome
In-Hospital Wearable-Based Monitoring Versus Standard Care in Cardiovascular Disease (INSPIRE)
Patients hospitalized with cardiovascular disease require timely detection of clinical deterioration to prevent adverse outcomes.
- Conditions
- Cardiovascular Diseases, Acute Coronary Syndrome, Heart Failure, Cardiac Arrhythmia
- Trial name
- NCT07622485
- Testing
- thynC Inpatient Monitoring System
- Where
- South Korea
- Volunteers
- 1,500 people
- Sponsor
- Yonsei University
Peripheral Arterial Disease
Structured EDucation for Rehabilitation in Intermittent Claudication
A primary therapeutic goal for patients with intermittent claudication (IC) is to regain lost physical function through exercise rehabilitation.
- Trial name
- SEDRIC (NCT01776710)
- Testing
- Structured education
- Where
- United Kingdom
- Volunteers
- 51 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Abdominal Aortic Aneurysm, Coronary Heart Disease NOS
Heart Rate and Initial Presentation of Cardiovascular Diseases (Caliber)
Study of heterogeneity in associations between heart rate and the initial presentation of 12 cardiovascular diseases.
- Conditions
- Abdominal Aortic Aneurysm, Coronary Heart Disease NOS, Unheralded Coronary Death, Intracerebral Haemorrhage
- Trial name
- NCT01947361
- Where
- United Kingdom
- Volunteers
- 1,961,286 people, healthy volunteers welcome
- Sponsor
- University College, London
Peripheral Arterial Disease
STEP: Proglide® Versus Femoseal®: A Trial to Compare the Efficacy of Arterial Closure Devices Following Endovascular Peripheral Arterial Procedures
Over the past years, arterial closure systems have tended to replace manual compression to ensure hemostasis at femoral artery puncture points.
- Trial name
- STEP (NCT03192033)
- Testing
- Arterial closure to ensure hemostasis at femoral artery puncture points, Proglide® (Abbott), Femoseal® (Terumo)
- Where
- 6 sites in France
- Volunteers
- 233 people
- Sponsor
- Nantes University Hospital
Peripheral Arterial Disease
This Study is a Prospective, Multi-center, Real World, Observational Study, Which Aims at Evaluating Intermediate and Long-term Efficacy of Endovascular Treatment for TASC C&D Aortoiliac Occlusive Disease.
This study is a prospective, multi-center, real world, observational study, which aims at evaluating the intermediate and long-term efficacy of endovascular treatment for TASC C\&D aortoiliac occlusive disease .It is estimated…
- Trial name
- NCT05391815
- Where
- China
- Volunteers
- 800 people
- Sponsor
- Shanghai Zhongshan Hospital
Atherosclerosis, Coronary Artery Disease
Feasibility of a Multifaceted Program to Reduce Cardiovascular Complications of Air Pollution
The main goal of this clinical trial is to evaluate the feasibility of conducting a large-scale clinical trial testing a program containing several aspects for reducing the effects of air pollution on cardiovascular health (which…
- Conditions
- Atherosclerosis, Coronary Artery Disease, Peripheral Arterial Disease, Ischemic Stroke
- Trial name
- NCT06261606
- Testing
- Hybrid strategy
- Where
- Iran
- Volunteers
- 50 people
- Sponsor
- Parham Sadeghipour
Peripheral Artery Disease, In-stent Restenosis
LDD in Treatment of Femoropopliteal ISR
This study will evaluate the effectiveness and safety of local drug delivery using TAPAS balloon catheter system in the treatment of femoropopliteal in-stent restenosis.
- Trial name
- NCT03521843
- Testing
- balloon dilation only, balloon dilation+local drug delivery
- Where
- China
- Volunteers
- 40 people
- Sponsor
- RenJi Hospital
Peripheral Artery Disease (PAD), Femoropopliteal Artery Disease
Chocolate Balloon vs Standard Balloon Angioplasty Before Drug-Coated Balloon Treatment for Femoropopliteal Artery Narrowing or Blockage
The goal of this clinical trial is to learn if using the Chocolate Percutaneous Transluminal Angioplasty (PTA) balloon for vessel preparation improves outcomes before drug-coated balloon (DCB) treatment in patients with…
- Conditions
- Peripheral Artery Disease (PAD), Femoropopliteal Artery Disease, Vascular Lesion Preparation, Critical Limb-Threatening Ischemia
- Trial name
- CHOICE (NCT07471087)
- Testing
- Chocolate PTA Balloon, Standard Balloon Angioplasty (POBA)
- Volunteers
- 242 people
- Sponsor
- Felice Pecoraro
Peripheral Artery Disease (PAD)
Infrared Thermal Imaging in Evaluating the Percutaneous Transluminal Angioplasty for Peripheral Artery Disease
Determination of IRTI (infrared thermal imaging) can be used to evaluate PAD patients with critical limb ischemia with different degrees of lesion.
- Trial name
- NCT05941533
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Fangge Deng
Diabetic Peripheral Neuropathy
Effect of High Tone External Muscle Stimulation on Peripheral Arterial Disease
to investigate the effect of high tone external muscle stimulation (HTEMS) on endothelial dysfunction and walking parameters in peripheral vascular disease.
- Trial name
- NCT04555876
- Testing
- high tone external muscle stimulation- stationary bicycle
- Volunteers
- 60 people
- Sponsor
- Cairo University
Arthroplasty Complications, Muscle Weakness
Achilles Tendon for the Treatment of Gluteus Medius Insufficiency
Residual limping after total hip arthroplasty is a serious complication that lacks effective treatment. The purpose of this study is to evaluate a surgical treatment for residual limping and compare its results with non-surgical…
- Conditions
- Arthroplasty Complications, Muscle Weakness, Muscle Atrophy, Muscle Tear
- Trial name
- HLS (NCT05206838)
- Testing
- Surgical reconstruction of gluteus medius with Achilles tendon allograft
- Where
- Sweden
- Volunteers
- 44 people
- Sponsor
- Sahlgrenska University Hospital
Critical Limb Ischemia
Investigating the Safety and Efficacy of the Treatment With Luminor DCB and Angiolite DES of iVascular in TASC C and D Tibial Occlusive Disease in Patients With Critical Limb Ischemia
This study aims to evaluate the 12 month outcome of the mono- or combination therapy with iVascular Luminor DCB and Angiolite DES for treatment of TASC C and TASC D long tibial occlusive disease, presenting with critical limb…
- Trial name
- MERLION (NCT04073121)
- Testing
- Luminor DCB and Angiolite DES
- Where
- 2 sites in Singapore
- Volunteers
- 50 people
- Sponsor
- Singapore General Hospital
Peripheral Artery Disease
Tack Optimized Balloon Angioplasty Study of the Tack Endovascular System™ in Femoropoliteal Arteries
This is a prospective, multi-center, single-arm, non-blinded study designed to investigate the safety and efficacy of the Tack Endovascular System in subjects with post-balloon angioplasty (post-PTA) dissection(s) type(s) A…
- Trial name
- TOBA II (NCT02522884)
- Testing
- Tack Endovascular System
- Where
- 39 sites in United States, Austria and 1 more
- Volunteers
- 213 people
- Sponsor
- Philips Clinical & Medical Affairs Global
Peripheral Artery Disease, Peripheral Vascular Disease
Safety of Intramuscular Injection of Allogeneic PLX-PAD Cells for the Treatment of Critical Limb Ischemia
The The purpose of this study is to determine the safety of PLX-PAD single dose, Intra-muscular injection for the treatment of CLI patients.
- Conditions
- Peripheral Artery Disease, Peripheral Vascular Disease, Critical Limb Ischemia
- Trial name
- NCT00919958
- Testing
- PLX-PAD IM injection
- Where
- Germany
- Volunteers
- 15 people
- Sponsor
- Pluristem Ltd.
Peripheral Arterial Diseases
The Jetstream (JET) Post-market Registry
The scope of the JET registry to observe long term treatment effects of Jetstream Navitus on various lesions types/morphologies.
- Trial name
- JET (NCT01436435)
- Testing
- Jetstream Atherectomy System
- Where
- 11 sites in United States
- Volunteers
- 241 people
- Sponsor
- Boston Scientific Corporation
Peripheral Artery Disease (PAD)
Detecting Peripheral Artery Disease With the Pulse
1) The purpose of this study is to assess segmental pulse arrival time (PAT) as an alternative biomarker to detect lower-extremity peripheral artery disease (PAD), and to investigate the impacts of local skin heating and foot…
- Trial name
- NCT07226193
- Testing
- Segmental pulse arrival time assessment
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Peripheral Arterial Disease
Safety and Effectiveness of Jetstream Atherectomy System (J-SUPREME II)
The purpose of this study is to evaluate the safety and effectiveness of the Jetstream Atherectomy System for the treatment of Japanese patients with symptomatic occlusive atherosclerotic lesions in native superficial femoral…
- Trial name
- NCT03847233
- Testing
- Jetstream Atherectomy System
- Where
- 5 sites in Japan
- Volunteers
- 31 people
- Sponsor
- Boston Scientific Corporation
Peripheral Arterial Disease
Augmentation of Limb Perfusion With Contrast Ultrasound
Our laboratory has discovered that ultrasound (US) imaging together with clinically approved microbubble ultrasound contrast agents can augment limb tissue perfusion.
- Trial name
- NCT03195556
- Testing
- Ultrasound
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Femoropopliteal Artery Disease
Korean Multicenter Registry of INNOVA Stent for Femoropopliteal Artery Disease: (K-INNOVA Registry)
Prospective, single-arm, multi-center registry study A total of 150 subjects with femoropopliteal artery disease who meet all inclusion and exclusion criteria will be included.
- Trial name
- NCT02701816
- Testing
- innova stent (Boston scientific)
- Where
- South Korea
- Volunteers
- 150 people
- Sponsor
- Yonsei University
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