Clinical trials: PAD - Peripheral Arterial Disease
Peripheral Arterial Disease
To Investigate the Effect of Far-infrared Radiation on Lower Extremity Acupoints on the Blood Circulation of Lower Extremities in Patients With Hemodialysis
This study intends to irradiate the acupoints of both lower extremities of hemodialysis patients with far-infrared therapeutic apparatus to explore its effect on foot blood circulation, peripheral artery occlusion disease (PAOD)…
- Trial name
- NCT05822960
- Testing
- far-infrared radiation
- Where
- 2 sites in Taiwan
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Peripheral Arterial Disease
The Effect of One Session Osteopathic Manuel Treatment on Femoral Artery Diameter and Flow
The aim of this study was to investigate the effect of one session OMT on arterial circulation in patients with PAD.
- Trial name
- NCT03928860
- Testing
- OMT session
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Kırıkkale University
Angioplasty, Peripheral Arterial Disease
European All-comers' Multicentric Prospective REGISTRY on LUMINOR© Drug Eluting Balloon in the Superficial Femoral Artery and Popliteal Artery With 5 Years Follow-up.
The objective of this all-comers registry is to explore the safety, efficacy, and cost-efficiency of the LUMINOR© DEB in de-novo and restenotic-FP lesions.
- Conditions
- Angioplasty, Peripheral Arterial Disease, Drug-eluting Balloon, Femoral Artery
- Trial name
- LUMIFOLLOW (NCT04743180)
- Testing
- LUMINOR© Paclitaxel eluting balloon
- Where
- 15 sites in France
- Volunteers
- 500 people
- Sponsor
- iVascular S.L.U.
Coronary Artery Disease, Carotid Artery Disease
Assessment Of Vascular Health After Niacin Therapy (AVANT)
This study is looking to see if niacin will lessen atherosclerotic plaque inflammation and favorably affect circulating levels of endothelial progenitor cells and microparticles in people with atherosclerotic disease on chronic…
- Conditions
- Coronary Artery Disease, Carotid Artery Disease, Peripheral Artery Disease
- Trial name
- AVANT (NCT02003638)
- Testing
- Niacin
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Pennsylvania
Coronary Artery Disease (CAD), Peripheral Arterial Disease
A Study of SRSD107 in Participants With Chronic Coronary and/or Peripheral Arterial Disease
The study is a Phase 2a, randomized, double-blind, placebo-controlled, sequential cohort study to evaluate the pharmacodynamics (PD), safety and pharmacokinetics (PK) of multiple doses of SRSD107 in participants with coronary…
- Trial name
- NCT07318155
- Testing
- SRSD107, 0.9 % sodium chloride
- Where
- China
- Volunteers
- 104 people
- Sponsor
- Sirius Therapeutics Co., Ltd.
Peripheral Artery Occlusive Disease
Xeltis Peripheral Artery Disease (XPAD) Bypass Conduit Early Feasibility Study
A prospective, single arm, non-randomized early feasibility study to evaluate the preliminary safety and performance of the XPAD conduit in patients with peripheral arterial occlusive disease (PAOD), scheduled to undergo elective…
- Trial name
- NCT06951685
- Testing
- Xeltis Peripheral Artery Disease (XPAD) Bypass Conduit
- Where
- Costa Rica
- Volunteers
- 6 people
- Sponsor
- Xeltis
Peripheral Arterial Disease
Adapted Physical Activity in Patients With Lower Limb Peripheral Arterial Disease
The prevalence of peripheral arterial disease is 12.2% in France. Intermittent claudication is the most common symtom of this disease. During physical exercise, such as walking, blood oxygen (O2) requirements increase.
- Trial name
- ACTIV'AO (NCT04800276)
- Testing
- muscle strengthening targeted on ischemic areas, global muscle strenghtening
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Centre Hospitalier le Mans
Intermittent Claudication
Hospital- and Home-based Supervised Exercise Versus UNsupervised Walk Advice For Patients With InTermittent Claudication
The purpose of this randomized clinical trial is to determine and compare the clinical and cost effectiveness of three methods for exercise therapy as treatment for patients with intermittent claudication.
- Trial name
- SUNFIT (NCT02341716)
- Testing
- WA, SET, HET
- Where
- 2 sites in Sweden
- Volunteers
- 165 people
- Sponsor
- Lennart Jivegård
Peripheral Artery Disease
Claudication, Systematic Evaluation of Limp on Treadmill
Vascular claudication is a common cause of functional limitation. This painful condition is a source overall muscle deconditioning in the peripheral arterial diseased (PAD) patient leading gradually to a state accented…
- Trial name
- CLAUSEL (NCT02754804)
- Testing
- Biomechanic parameters
- Where
- France
- Volunteers
- 190 people
- Sponsor
- University Hospital, Angers
Peripheral Arterial Disease
Cardiac Rehabilitation Program in Peripheral Arterial Disease
The main purpose of this study is to see if it is safe and feasible to use cardiac rehabilitation (CR) in patients with peripheral arterial disease (PAD) after successful revascularization.
- Trial name
- NCT03251391
- Testing
- Cardiac Rehabilitation Program, Conventional Therapy
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Kansas Medical Center
PAD - Peripheral Arterial Disease, PAD
Distrupt Stiffness Trial
Typical symptoms of PAD include exercise-induced pain in the legs (known as intermittent claudication), which can significantly limit pain-free walking. In more advanced stages, pain may also occur at rest.
- Trial name
- NCT07130526
- Testing
- Intravascular Lithotripsy (IVL) plus DCB, POBA plus DCB
- Where
- 2 sites in Germany
- Volunteers
- 40 people
- Sponsor
- University Hospital, Essen
Intermittent Claudication
Home-based Exercice Therapy for Patients With Intermittent Claudication Using a New Smartphone Application
The main characteristic of PAD is to limit physical activity by the appearance of claudication of the lower limbs which limits the walking distance, or the maximum distance traveled by the patient before the pain forces to stop.
- Trial name
- APAISE (NCT05457738)
- Testing
- E-REVA® app, No E-REVA® app
- Where
- France
- Volunteers
- 52 people
- Sponsor
- CHU de Reims
Peripheral Arterial Disease
To Evaluate the Introduction of a Public Health Approach to Peripheral Arterial Disease (PAD) Using National Centre for Sport and Exercise Medicine Facilities.
The aim of the project is to investigate the clinical and patient centred outcomes of people with Peripheral Arterial Disease (PAD) attending a podiatry led integrated care pathway, utilising advice on diet, activity and smoking…
- Trial name
- PodPAD (NCT02901847)
- Testing
- PAD tailored care
- Where
- United Kingdom
- Volunteers
- 21 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Chronic Obstructive Pulmonary Disease, Peripheral Artery Disease
Chronic Obstructive Pulmonary Disease in Combination With Atherosclerosis (Clinical and Biochemical Study)
one-centered, open, non-randomized, controlled clinical trial will focus on a comprehensive study of the clinical, functional and molecular biochemical characteristics of the natural course of COPD in combination with peripheral…
- Trial name
- NCT04474717
- Testing
- Breath Condensate Collection, clinical examination, spirometry, blood monocyte assay
- Where
- Russia
- Volunteers
- 476 people
- Sponsor
- Ryazan State Medical University
Aortic Aneurysm, Peripheral Arterial Disease
Validation of the Cheetah NICOM by Comparison to TEE During Open Vascular Surgery - Pilot Study
The Cheetah NICOM is a non-invasive cardiac output monitor that has been validated in various clinical contexts but not during the occlusion of major arteries, as takes place in vascular surgery.
- Trial name
- NCT02630550
- Testing
- Cheetah NICOM, Transesophageal echocardiography (TEE)
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Maisonneuve-Rosemont Hospital
Critical Limb Ischemia
Cardiovascular Clinical Project to Evaluate the Regenerative Capacity of CardioCell in Patients With No-option Critical Limb Ischemia (N-O CLI)
The main objective of the CIRCULATE project is to compare the clinical outcomes of CardioCell administration in treatment of ischemic damages of cardiovascular system with control group, who will be treated by the administration…
- Trial name
- NCT03423732
- Testing
- CardioCell
- Where
- 2 sites in Poland
- Volunteers
- 50 people
- Sponsor
- John Paul II Hospital, Krakow
Diabetes, Peripheral Arterial Disease
Effects of High Voltage Electrical Stimulation, Shortwave Diathermy and Kinesiotherapy on Arterial Blood Flow in the Lower Limbs of Diabetic Women
Peripheral arterial disease (PAD) is a pathological condition limiting, resulting from a narrowing or occlusion of the artery diameter due to aneurysms, inflammation, atherosclerosis and thromboembolic events.
- Trial name
- NCT01868698
- Testing
- high-voltage electrical stimulation, Kinesiotherapy, shortwave diathermy
- Where
- Brazil
- Volunteers
- 15 people
- Sponsor
- University of Sao Paulo
Coronary Artery Disease, Cerebral Vascular Disease
Pilot Study: Cardiovascular Events in High Risk Orthopedic Surgical Patients
This is a non-randomized, non-interventional pilot observational study designed to follow high-risk patients through their surgical and hospital stay.
- Conditions
- Coronary Artery Disease, Cerebral Vascular Disease, Peripheral Artery Disease, Renal Insufficiency
- Trial name
- NCT01809730
- Where
- United States
- Sponsor
- NYU Langone Health
Rheumatoid Arthritis, Ankylosing Spondylitis
PatientSpot Formerly Known as ArthritisPower
Patient Power is a patient research network and database (registry) to collect prospective information about demographics, self-reported diagnoses and medications, and willingness to participate in research from participants with…
- Conditions
- Rheumatoid Arthritis, Ankylosing Spondylitis, Fibromyalgia, Gout
- Trial name
- NCT03840928
- Where
- United States
- Volunteers
- 40,000 people, healthy volunteers welcome
- Sponsor
- Global Healthy Living Foundation
Arterial Occlusive Diseases
Study of Alfimeprase's Ability to Dissolve Blood Clots in the Leg and Help Prevent the Need for Surgery
The purpose of this study is to directly compare the safety and efficacy of intra-thrombus alfimeprase 0.3 mg/kg with placebo in acute peripheral arterial occlusion (PAO) as measured by a 30 day open vascular free surgery rate.
- Trial name
- NCT00338585
- Testing
- alfimeprase
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- ARCA Biopharma, Inc.
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