Clinical trials: PAD - Peripheral Arterial Disease
Critical Limb Ischemia, Vascular Diseases
A Phase IIB Pilot Study of a Modified Dosage Regimen of AMG0001 in Subjects With Critical Limb Ischemia
The purpose of the study is to confirm the feasibility of study procedures and the tolerability of a new dose regimen of AMG0001 in subjects with Critical Limb Ischemia (CLI)
- Conditions
- Critical Limb Ischemia, Vascular Diseases, Peripheral Arterial Disease
- Trial name
- NCT02016755
- Testing
- HGF Plasmid
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- AnGes USA, Inc.
Critical Limb Ischemia
YQ23 Study in Patients With Critical Limb Ischaemia
This is an early phase study to assess how safe and tolerable is the new study drug YQ23 and to compare the effectiveness of YQ23 against normal saline to treat critical limb ischaemia.
- Trial name
- YAN (NCT04792008)
- Testing
- YQ23
- Where
- 2 sites in Hong Kong
- Volunteers
- 5 people
- Sponsor
- New Beta Innovation Limited
Peripheral Arterial Disease
The Effect of One Session Osteopathic Manuel Treatment on Femoral Artery Diameter and Flow
The aim of this study was to investigate the effect of one session OMT on arterial circulation in patients with PAD.
- Trial name
- NCT03928860
- Testing
- OMT session
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Kırıkkale University
Peripheral Arterial Disease, Sedentary Behavior
RESPONSE-2-PAD to Reduce Sedentary Time in Peripheral Arterial Disease Patients
The RESPONSE-2- peripheral arterial disease (PAD) program will be implemented to modify sedentary time in patients with PAD. It is an adapted version of the RESPONSE that aims to reduce sedentary behavior in individuals with…
- Conditions
- Peripheral Arterial Disease, Sedentary Behavior, Sedentary Time, Peripheral Arterial Occlusive Disease
- Trial name
- NCT05961943
- Testing
- RESPONSE-2-PAD
- Where
- Ireland
- Volunteers
- 50 people
- Sponsor
- National Institute for Prevention and Cardiovascular Health, Ireland
Peripheral Arterial Disease
The Jetstream G3™ Calcium Study
To investigate the treatment effects with the Jetstream G3 System in moderate to severely calcified peripheral artery disease in the common femoral, superficial femoral or popliteal arteries using intravascular ultrasound (IVUS).
- Trial name
- NCT01273623
- Testing
- Jetstream Atherectomy System
- Where
- 5 sites in United States
- Volunteers
- 55 people
- Sponsor
- Boston Scientific Corporation
Peripheral Artery Disease (PAD)
Use of Three-Dimensional Printed Models for Endovascular Planning and Follow-up in Patients Affected by Aorto-Iliac-Femoral-Popliteal Arterial Disease Undergoing Balloon Angioplasty. A Single-center, Single-blind Randomized Controlled Trial
Lower extremity peripheral arterial disease is a major health problem. Currently, balloon angioplasty represents the most commonly performed treatment for patients affected by vascular claudication or critical limb ischemia.
- Trial name
- 3DPAD-1 (NCT07000097)
- Testing
- PTA planning supported by 3D-printed model, PTA (Standard of Care)
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Azienda Ospedaliero-Universitaria di Parma
Ischemic Stroke
The Safety and Efficacy of Cilostazol in Ischemic Stroke Patients With Peripheral Arterial Disease (SPAD Study)
The purpose of this study is to investigate the Safety and Efficacy of Cilostazol in slowing down the progression of peripheral arterial disease (PAD) in ischemic stroke patients with PAD in Taiwan.
- Trial name
- NCT01188824
- Testing
- Cilostazol
- Volunteers
- 801 people
- Sponsor
- China Medical University Hospital
Peripheral Arterial Disease
Optimization of Treatment in Patients With Severe Peripheral Ischemia (Fontaine Stage IIb)
Evaluate the possibility of optimization of therapy with prostanoids (iloprost), in patients with Fontaine's stage IIb severe chronic ischemia, both in patients eligible for surgery both in patients for which it is only possible…
- Trial name
- 2bPILOT (NCT01718288)
- Testing
- iloprost, Standard Treatment (aspirin.....),
- Where
- 14 sites in Italy
- Volunteers
- 150 people
- Sponsor
- Fadoi Foundation, Italy
Femoral Artery Stenosis, Popliteal Artery Stenosis
IN.PACT Admiral Drug-Coated Balloon vs. Standard Balloon Angioplasty for the Treatment of Superficial Femoral Artery (SFA) and Proximal Popliteal Artery (PPA)
The purpose of the study is to demonstrate the safety and efficacy of the IN.PACT Admiral drug-coated balloon (DCB) in comparison to any standard balloon for treatment of peripheral arterial disease (PAD) in the superficial…
- Conditions
- Femoral Artery Stenosis, Popliteal Artery Stenosis, Femoral Artery Occlusion, Popliteal Artery Occlusion
- Trial name
- INPACT SFA II (NCT01566461)
- Testing
- Drug-Coated Balloon (DCB), PTA Balloon: Balloon Angioplasty
- Where
- 2 sites in United States
- Volunteers
- 331 people
- Sponsor
- Medtronic Endovascular
Chronic Limb Threatening Ischemia
Vessel Recoil in Specific CLTI Populations
Chronic limb threatening ischemia (CLTI) represents the most advanced stage of peripheral arterial disease (PAD) and is characterized by ischemic rest pain, non-healing wounds, or ischemic gangrene.
- Trial name
- NCT07465627
- Testing
- Vessel recoil measurement 15 minutes post final treatment (angiographically)
- Where
- Austria
- Volunteers
- 40 people
- Sponsor
- Medical University of Graz
Aneurysm Abdominal, Peripheral Arterial Disease
Developing Trustworthy Artificial Intelligence (AI)-Driven Tools to Predict Vascular Disease Risk and Progression
The VASCULAID-RETRO study, within the broader VASCULAID project, aims to create artificial intelligence (AI) algorithms that can predict cardiovascular events and the progression of abdominal aortic aneurysm (AAA) and peripheral…
- Trial name
- VASCULAIDRETRO (NCT06206369)
- Testing
- No intervention, retrospective study
- Where
- 6 sites in Finland, Germany and 4 more
- Volunteers
- 11,000 people
- Sponsor
- Amsterdam UMC, location VUmc
Peripheral Artery Disease, Intermittent Claudication
Observational Feasibility Study of Home-based Training With Therabands in PAD-patients
The study is an observational feasibility study to evaluate the feasibility of a combined aerobic+resistance training program in patients with IC.
- Trial name
- NCT04043546
- Testing
- aerobic+resistance exercise training program
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- KU Leuven
Peripheral Artery Disease, Claudication, Intermittent
Lactate Increase in Peripheral Artery Disease
To our knowledge, the measurement of the transcutaneous oxygen pressure during walking is the only continuous method that estimates the importance of ischemia, bilaterally and segment of limb by segment of limb.
- Trial name
- STELLA (NCT03266861)
- Testing
- Exercise oximetry
- Where
- France
- Volunteers
- 750 people
- Sponsor
- University Hospital, Angers
Critical Limb Ischemia, Peripheral Artery Disease
Natural Progression of High-Risk Chronic Limb-Threatening Ischemia: The CLariTI Study
The objective of this observational registry is to track the clinical progression of chronic limb-threatening ischemia (CLTI) and incidence of death, amputation, and revascularization attempts over a one-year period.
- Trial name
- NCT04304105
- Where
- 25 sites in United States, Puerto Rico
- Volunteers
- 192 people
- Sponsor
- LimFlow, Inc.
Peripheral Vascular Disease, Critical Limb Ischemia
Near Infrared Spectroscopy and Transcutaneous Oxygen Pressure in Critical Limb Ischemia Before and After Treatment
Comparison of two non-invasive methods for measuring tissue oxygenation. One is Transcutaneous Oxygen Pressure (TCPO2) and the other is the new method of Near Infrared Spectroscopy (NIRS) - near infrared spectroscopy in patients…
- Trial name
- NIRS (NCT01459341)
- Where
- Israel
- Volunteers
- 15 people
- Sponsor
- Carmel Medical Center
Peripheral Arterial Disease, Critical Limb Ischemia
BOLD MRI as a Surrogate of Improved Muscle Oxygenation Following Endovascular Therapy for the Treatment of CLI
The purpose of this study is to determine if an MRI technique called Blood Oxygen Level Dependent, or BOLD, can be used to evaluate blood flow in the leg before and after treatment with standard endovascular therapy in patients…
- Trial name
- NCT02601430
- Testing
- BOLD-MRI
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Zimmer Biomet
Peripheral Arterial Disease, Personal Satisfaction
CONTECI Program: A New Way to Control Peripheral Arterial Disease Using New Technologies
The current increase in chronic diseases calls for changes to the health system. It is necessary to promote expert patient in chronic disease.
- Conditions
- Peripheral Arterial Disease, Personal Satisfaction, Telemedicine
- Trial name
- NCT02762916
- Testing
- Selfmanage with the help of telemedicine program
- Volunteers
- 150 people
- Sponsor
- Consorci Sanitari del Maresme
Ischemia, Peripheral Arterial Disease
A Clinical and Histological Analysis of Mesenchymal Stem Cells in Amputation
Patients undergoing semi-elective lower extremity major amputation from complications associated with atherosclerotic limb ischemia will received intra-muscular injections of allogeneic Mesenchymal Stromal Cells in the leg above…
- Conditions
- Ischemia, Peripheral Arterial Disease, Peripheral Vascular Disease, Vascular Disease
- Trial name
- CHAMP (NCT02685098)
- Testing
- Allogeneic bone marrow derived mesenchymal stem cells
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- Indiana University
Peripheral Artery Disease
Validation of VascuQol-6 Spanish Version
VascuQol (VQ) is a specific questionnaire to assess the quality of life of patients with critical limb ischemia which is also used as an index in vascular registries.
- Trial name
- NCT04741321
- Testing
- VascuQol-6 questionnaire Spanish version
- Where
- 2 sites in Spain
- Volunteers
- 104 people
- Sponsor
- Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz
Post Thrombotic Syndrome, Venous Thromboses
Exercise Tolerance After Venous Recanalization for Post-thrombotic Syndrome
Post-thrombotic syndrome (PTS) is the most frequently observed chronic complication of deep vein thrombosis (DVT), with an estimated cumulative incidence of 20-50%.
- Conditions
- Post Thrombotic Syndrome, Venous Thromboses, Claudication, Intermittent
- Trial name
- ETERecaVSPT (NCT05794932)
- Testing
- Stress test
- Where
- France
- Volunteers
- 22 people
- Sponsor
- University Hospital, Montpellier
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.