Clinical trials: PAOD - Peripheral Arterial Occlusive Disease, open to volunteers
Peripheral Artery Disease, Peripheral Vascular Diseases
Impact of Nrf2 Activation on Macrovascular, Microvascular & Leg Function & Walking Capacity in Peripheral Artery Disease
Peripheral artery disease (PAD) is associated with elevated oxidative stress, and oxidative stress has been implicated as the cause of reduced endothelial reactivity in individuals with PAD.
- Conditions
- Peripheral Artery Disease, Peripheral Vascular Diseases, Peripheral Arterial Disease, Peripheral Arterial Occlusive Disease
- Trial name
- NCT06319339
- Testing
- Vumerity
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Peripheral Artery Disease
Prevalence of Obstructive Sleep Apnea in Patients With Peripheral Arterial Occlusive Disease
Obstructive sleep apnea syndrome (OSAS) is characterized by partial (hypopnea) or complete (apnea) obstruction of the upper airways, leading to intermittent hypoxemia and sleep fragmentation.
- Trial name
- OSAPAD (NCT07283289)
- Where
- France
- Volunteers
- 295 people
- Sponsor
- Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
Peripheral Arterial Occlusive Disease, Femoropopliteal Artery Occlusion
FRAMED Infrainguinal Venous Bypass Versus Conventional Autologous Bypass Trial
The purpose of this clinical trial is to analyze patency after autologous infrainguinal bypass surgery in patients receiving a venous conduit versus a covered venous conduit.
- Conditions
- Peripheral Arterial Occlusive Disease, Femoropopliteal Artery Occlusion, Femoropopliteal Stenosis, Critical Limb-Threatening Ischemia
- Trial name
- Framed IVB (NCT06082466)
- Testing
- FRAMED Infrainguinal Venous Bypass, Conventional Autologous Bypass
- Where
- Austria
- Volunteers
- 110 people
- Sponsor
- Paracelsus Medical University
Coronary Stenosis, Cerebral Arterial Diseases
Wearable Devices Assist in the Detection, Screening, and Management of Major Diseases in Middle-aged and Elderly Populations
The goal of this randomized controlled trial is to evaluate the effectiveness of wearable devices (Huawei smartwatches) in aiding the detection, and screening of major diseases (e.g., coronary artery disease, hypertension) in…
- Conditions
- Coronary Stenosis, Cerebral Arterial Diseases, Hypertension, Parkinson Disease
- Trial name
- NCT06980064
- Testing
- Smartwatch + GP, GP only
- Volunteers
- 800 people
- Sponsor
- Tongji Hospital
Peripheral Arterial Occlusive Disease, Chronic Limb-Threatening Ischemia
Safety of Antithrombotic Heparin Proteoglycan Mimetic APAC in Peripheral Arterial Occlusive Disease and Chronic Limb-threatening Ischemia
The goal of this study is to learn if a new medicine (called antiplatelet and anticoagulant [APAC]) can help the body to prevent blood clots and whether APAC is safe and well tolerated in patients with blocked or narrowed…
- Trial name
- HEALING (NCT07352800)
- Testing
- APAC - dose level 0.50 mg/kg,, Unfractionated heparin (UFH), APAC dose level 1: 0.25 mg/kg,
- Where
- 3 sites in Finland
- Volunteers
- 42 people
- Sponsor
- Aplagon Oy
Peripheral Occlusive Disease, Wound Healing
Intraoperative Application of Cold Atmospheric Plasma to Prevent Postoperative Wound Complications in the Inguinal Region of High-risk Patients With Peripheral Arterial Occlusive Disease
The goal of this clinical trial is to learn if postoperative wound complications in the inguinal region of high-risk patients with peripheral arterial occlusive disease can be prevented by the intraoperative application of cold…
- Conditions
- Peripheral Occlusive Disease, Wound Healing, Wound Healing Complication, Cold Atmospheric Plasma
- Trial name
- PICPAD (NCT07571408)
- Testing
- Cold atmospheric plasma
- Where
- Germany
- Volunteers
- 214 people
- Sponsor
- Ursula Werra
Diabetes Mellitus Type 2
Patients With Type 2 Diabetes
Diabetes mellitus
- Trial name
- NCT07245082
- Where
- Taiwan
- Volunteers
- 2,000 people
- Sponsor
- National Taiwan University Hospital
Peripheral Artery Occlusive Disease, Acute Coronary Syndrome
The Prevalence Survey of ALDH Gene Family in Patients With Peripheral Arterial Occlusive Disease or Acute Coronary Syndrome
Aldehyde dehydrogenase 2 (ALDH2) is an important enzyme protecting human from the accumulation of aldehyde, the main metabolites of alcohol.
- Trial name
- NCT05078814
- Testing
- Observational research
- Where
- Taiwan
- Volunteers
- 600 people
- Sponsor
- Chimei Medical Center