Clinical trials: PCA, open to volunteers
Multiple Mid-Transverse Process to Pleura, PCA
Analgesic Efficacy of Multiple Mid-Transverse Process to Pleura (MTP) Block and PCA in Idiopathic Scoliosis Patients Undergoing Posterior Spinal Fusion
This study aims to compare the analgesic efficacy of multiple mid-transverse process to pleura (MTP) block and PCA in idiopathic scoliosis patients undergoing posterior spinal fusion surgery.
- Conditions
- Multiple Mid-Transverse Process to Pleura, PCA, Idiopathic Scoliosis, Posterior Spinal Fusion
- Trial name
- NCT06820190
- Testing
- Multiple Mid-Transverse Process to Pleura (MTP) Block, Morphine
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Tanta University
Frontotemporal Degeneration (FTD), ALS (Amyotrophic Lateral Sclerosis)
Biofluid Research on Age-Related or Inherited Neurodegeneration
The aim of this study is to contribute to and continue to sustain a repository of blood samples, nucleic acid (DNA and/or RNA) samples, family history information, and other demographic information from individuals with…
- Conditions
- Frontotemporal Degeneration (FTD), ALS (Amyotrophic Lateral Sclerosis), Primary Progressive Aphasia (PPA), Familial Frontotemporal Lobar Degeneration (fFTLD)
- Trial name
- BRAIN (NCT07798700)
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Inguinal Hernia Unilateral, Postoperative Pain
Quadro-Iliac Plane Block for Postoperative Analgesia in Laparoscopic Inguinal Hernia Repair
The goal of this randomized controlled trial is to learn whether an ultrasound-guided quadro-iliac plane block (QIPB) reduces opioid use and pain after laparoscopic inguinal hernia repair in adults aged 18-65 years.
- Conditions
- Inguinal Hernia Unilateral, Postoperative Pain, Opioid Use
- Trial name
- QIPB-LIHR (NCT07878936)
- Testing
- Quadro-iliac plane block
- Volunteers
- 64 people
- Sponsor
- Marmara University Pendik Training and Research Hospital
Surgery, Pain Management
Comparison of the Efficacy and Safety of Fixed-rate Basal Infusion Mode and Time-programmed Decremental Background Infusion Mode of Intravenous PCA Following Mixed Surgery
Perioperative pain management affects patient recovery. However, the rate of moderate to severe postoperative pain is as high as 73.8%, which hinders recovery and increases the risk of complications.
- Conditions
- Surgery, Pain Management, Opioid Consumption, Patient Controlled Analgesia
- Trial name
- NCT07375121
- Testing
- Fixed-rate basal infusion mode, Time-programmed decremental background infusion mode
- Where
- China
- Volunteers
- 450 people
- Sponsor
- Beijing Tiantan Hospital
Laparotomy
IV vs Epidural Opioids + Epidural Local Anesthetic for Laparotomy Analgesia
The purpose of this research study is to determine if the two common ways of administering additional opioids (morphine like substance, narcotic) with an epidural, either mixed in the epidural solution or given separately through…
- Trial name
- NCT06559969
- Testing
- Intravenous administered opioid, Epidural administered opioid
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Iowa
Breast Cancer
Analgesic Efficacy of Maxigesic in Breast Cancer Surgery
The present study aims to find a perioperative analgesic method that provides sufficient analgesia while reducing immune compromise in cancer surgery. This study is to investigate the analgesic effect and safety of Maxigesic inj.
- Trial name
- NCT06174363
- Testing
- Maxigesic, 0.9% saline solution
- Where
- South Korea
- Volunteers
- 84 people
- Sponsor
- Yonsei University
Pathological and Imaging Examinations Confirmed Metastatic Prostate Cancer
Clinical Study of Rezvilutamide Combined With Docetaxel Chemotherapy in the Treatment of Abiraterone-Resistant Prostate Cancer
Emphasize the main 4 points. 1. Trial Name: Evaluate the efficacy and safety of Rezvilutamide combined with docetaxel in the treatment of abiraterone-resistant prostate cancer. 2.
- Trial name
- NCT07112209
- Testing
- Rezvilutamide combined with docetaxel
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Zhujiang Hospital
Prostate Cancer (Adenocarcinoma), Erectile Abnormalities
PRIAPUS-PCa Study: Stereotactic Body Radiation Therapy (SBRT) and Androgen Deprivation Therapy (ADT) Impact on Sexual Function on Men With Unfavorable Intermediate Risk Prostate Cancer
This study looks at how combined radiation and hormone therapy affects sexual function in men with a specific type of prostate cancer, before and after treatment.
- Conditions
- Prostate Cancer (Adenocarcinoma), Erectile Abnormalities, Sexual Dysfunction Male
- Trial name
- PRIAPUS-PCa (NCT07460726)
- Testing
- SBRT combined with ADT
- Where
- Canada
- Volunteers
- 130 people
- Sponsor
- CancerCare Manitoba
Frontotemporal Degeneration(FTD), Primary Progressive Aphasia(PPA)
UPenn Observational Research Repository on Neurodegenerative Disease
The aim of this study is to create a repository of both cross-sectional and longitudinal data, including cognitive, linguistic, imaging and biofluid biological specimens, for neurodegenerative disease research and treatment.
- Conditions
- Frontotemporal Degeneration(FTD), Primary Progressive Aphasia(PPA), Familial Frontotemporal Lobar Degeneration (fFTLD), Amyotrophic Lateral Sclerosis(ALS)
- Trial name
- UNICORN (NCT04715399)
- Testing
- No intervention
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Alzheimer's Disease, Fronto-temporal Dementia
Pilot Trial Evaluating Patient Experience With the MemorEM for Patients With Neurological Diseases
Primary Objective: The primary objective of this pilot study is to gain voluntary feedback from patients with neurological diseases and their caregivers regarding their experiences using the MemorEM head device.
- Conditions
- Alzheimer's Disease, Fronto-temporal Dementia, Parkinson Disease (PD), Cortico Basal Degeneration
- Trial name
- NCT07049341
- Testing
- MemorEM
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- NeuroEM Therapeutics, Inc.
Prostate Adenocarcinoma
PSMA PET Response Guided SabR in High Risk Pca
Sequential cohort evaluation of ideal timing of imaging and treatment spacing to discern maximal PSMA (Prostate specific membrane antigen) PET (Positron Emission Tomography) response (PSMA-11 68Ga, Illucix) for adaptation of…
- Trial name
- NCT06044857
- Testing
- 68-Ga PSMA11
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- University of Texas Southwestern Medical Center
Renal Cell Carcinoma
Comparison of Postoperative Analgesic Efficacy of the Erector Spina Plane Block and Quadratus Lumborum Block in Open Nephrectomy: a Prospective Randomized Clinical Study
patients who will undergo elective open nephrectomy will be divided into three groups; the control (PCA), the erector spina plane block, and the quadratus lumborum block.
- Trial name
- NCT05810571
- Testing
- preoperative remifentanil consumption, postopeartive controlled anlagesia with morphine
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Kocaeli University
Postoperative Pain, Laparoscopic Cholecystectomy
External Oblique Intercostal Block (EOICB) for Laparoscopic Cholecystectomy
This single-center, prospective, randomized controlled trial aims to compare the effects of paravertebral block (PVB), external oblique intercostal (EOI) block, and intravenous patient-controlled analgesia (PCA) with tramadol on…
- Conditions
- Postoperative Pain, Laparoscopic Cholecystectomy, Paravertebral Block, External Oblique Intercostal Plane Block
- Trial name
- NCT07241949
- Testing
- Paravertebral Block (PVB), External Oblique Intercostal Block (EOI Block), Tramadol IV Patient-Controlled Analgesia (PCA)
- Where
- Turkey (Türkiye)
- Volunteers
- 147 people
- Sponsor
- Cukurova University