Clinical trials: PCOS (Polycystic Ovary Syndrome)
Polycystic Ovary Syndrome
Acupuncture for Insulin Resistance in Women With Polycystic Ovary Syndrome
This two-stage clinical research programme aims to evaluate the preliminary effectiveness and safety of acupuncture for improving insulin resistance in women with polycystic ovary syndrome (PCOS).
- Trial name
- NCT07806656
- Testing
- Active Acupuncture, Lifestyle Management
- Where
- China
- Volunteers
- 204 people
- Sponsor
- Peking University Third Hospital
Infertility, Polycystic Ovaries
Invitro Maturation of Oocytes for Patients With Polycystic Ovaries
In vitro maturation of oocytes after minimal gonadotropin stimulation in patients with polycystic ovaries, to prevent cases of ovarian hyperstimulation.
- Trial name
- NCT00631982
- Testing
- in vitro matuartion of oocytes
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Assaf-Harofeh Medical Center
PCOS (Polycystic Ovary Syndrome), Obese Adolescents
Lean Beef as Part of a Healthy Meal Plan in Adolescents With Polycystic Ovary Syndrome (PCOS)/Polyendocrine Metabolic Ovarian Syndrome (PMOS)
This pilot randomized controlled study will plan to enroll 36 adolescent females with Polycystic Ovary Syndrome (PCOS)/Polyendocrine Metabolic Ovarian Syndrome (PMOS) to evaluate the effectiveness and feasibility of a tailored…
- Conditions
- PCOS (Polycystic Ovary Syndrome), Obese Adolescents, Overweight (Without Type 2 Diabetes) With Weight-related Comorbidities, Overweight Adolescents
- Trial name
- Beef+ (NCT07780188)
- Testing
- Beef+
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Texas A&M University
Polycystic Ovary Syndrome, Diminished Ovarian Reserve
Clinical Trial of Anovulatory Infertility
This project aims to study the expression of clock genes and related proteins in follicular fluid and granulosa cells, depicting the periodic, amplitude, and phase changes of biological clock genes and related proteins in women…
- Conditions
- Polycystic Ovary Syndrome, Diminished Ovarian Reserve, Ovulation Disorder
- Trial name
- NCT06601452
- Testing
- a compound prescription of Chinese medicine
- Where
- China
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- Affiliated Hospital of Nanjing University of Chinese Medicine
Polycystic Ovary Syndrome, Obesity
Low Dose Liraglutide and Metformin vs. High Dose Liraglutide Alone in Treatment of Obesity
Weight reduction is the most important treatment target when polycystic ovary syndrome (PCOS) is linked to obesity. Liraglutide (LIRA) in dose of 3 mg was recently approved as an anti-obesity drug.
- Trial name
- NCT02909933
- Testing
- liraglutide, metformin and liraglutide
- Where
- Slovenia
- Volunteers
- 30 people
- Sponsor
- University Medical Centre Ljubljana
Polycystic Ovary Syndrome (PCOS), Metabolic Syndrome
Malay Women With PCOS and Their Association With Metabolic Syndrome
The abnormalities that characterize the Metabolic Syndrome (MetS) confer an increased risk of cardiovascular and other diseases.
- Trial name
- MPMSS (NCT03414957)
- Testing
- Hormonal and biochemical blood tests and ultrasound scanning
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Cyberjaya University College of Medical Sciences
Metabolic Syndrome, Polycystic Ovary Syndrome
Evaluation of Licorice Root on Metabolic Syndrome in Polycystic Ovary Syndrome Females
The goal of this study is to learn about the effect of licorice root powder on parameters of metabolic syndrome in those women diagnosed with PCOS with age range of 15-49 years of age.
- Trial name
- NCT06043375
- Testing
- Licorice Root Powder Capsule
- Where
- Pakistan
- Volunteers
- 55 people
- Sponsor
- University of Veterinary and Animal Sciences, Lahore - Pakistan
PCOS, NAFLD
Non-alcoholic Fatty Liver Disease in Women With Polycystic Ovary Syndrome
This study was planned to examine the prevalence of vitamin D insufficiency, insulin resistance, non-alcoholic fatty liver disease (NAFLD), and their relationship with each other and the nutritional status of individuals with…
- Trial name
- NCT05843955
- Testing
- Questionnaire
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Hacettepe University
Polycystic Ovary Syndrome
Effect of Metformin and Probiotics in Reproductive-aged Patients With Polycystic Ovary Syndrome
The purpose of this clinical trial is to evaluate the safety and effectiveness on the clinical and biological parameters of reproductive-aged PCOS women after a 12-week metformin and/or probiotics administration.
- Trial name
- NCT03336840
- Testing
- Metformin tablets, ProMetS probiotics powder, 1. Metformin tablets; 2. ProMetS probiotics powder
- Where
- China
- Volunteers
- 90 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Polycystic Ovary Syndrome
Improved Effects of MI Plus Alpha-LA in PCOS
PCOS patients are initially treated with 2 g myo-inositol and 0.2 mg folic acid, two times per day by oral route, for three months.
- Trial name
- NCT03422289
- Testing
- myo-inositol plus folic acid, myo-inositol plus folic acid plus alpha-lactalbumin
- Where
- Italy
- Volunteers
- 37 people
- Sponsor
- Lo.Li.Pharma s.r.l
PCOS
Insulin and Polycystic Ovary Syndrome
Increased insulin levels leads to increased secretion of D-chiro inositol(DCI) from the kidneys in women with PCOS, but not in normal women.
- Trial name
- NCT00683774
- Testing
- diazoxide
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Polycystic Ovary Syndrome
Metformin and Oral Contraceptives in PCOS
Background: PCOS is a common condition with a prevalence of 5-8 % in premenopausal women. More than 50% of PCOS patients are insulin resistant and have a diabetes risk 5-8 times higher than age- and weight-matched controls.
- Trial name
- NCT00451568
- Testing
- Metformin, Desorelle
- Where
- Denmark
- Volunteers
- 90 people
- Sponsor
- Odense University Hospital
Hyperandrogenism, Metabolic Cardiovascular Syndrome
Phlebotomy and Polycystic Ovary Syndrome
AIMS To study the effects of the decrease in iron tissue depots after scheduled bloodletting on insulin sensitivity, carbohydrate metabolism, classic and non-classic cardiovascular risk factors in patients with functional…
- Trial name
- NCT02460445
- Testing
- Phlebotomy, ethinylestradiol, Cyproterone Acetate
- Where
- Spain
- Volunteers
- 37 people
- Sponsor
- Manuel Luque Ramírez
Polycystic Ovary Syndrome
Efficacy of Dapagliflozin Versus Metformin in Polycystic Ovary Syndrome
In PCOS (Polycystic Ovary Syndrome), studies have found impaired incretin secretion and activity, particularly in overweight/obese individuals.
- Trial name
- NCT06576375
- Testing
- Dapagliflozin, Metformin
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Future University in Egypt
Polycystic Ovarian Syndrome
In Vitro Maturation (IVM) for Polycystic Ovary Syndrome (PCOS)
This pilot study will be a prospective investigation to study the efficacy and safety of In-Vitro Maturation (IVM) for women with Polycystic Ovarian Syndrome (PCOS). There will be 10 subjects total in this Study.
- Trial name
- NCT01237106
- Testing
- IVM
- Where
- 2 sites in United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University Reproductive Associates
PCOS, Diet Modification
Low Starch Dietary Education Program vs. Traditional Treatment for PCOS
Compare weight loss and metabolic parameters in patients using a low starch dietary education program vs. traditional treatment (i.e., prescribing metformin, low calorie diet and exercise) for health improvement in women with…
- Conditions
- PCOS, Diet Modification, Metabolism, Nutrition Disorders
- Trial name
- NCT03916263
- Testing
- Metformin, One-On-One Dietary Instruction, Video Dietary Instruction
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Texas Tech University Health Sciences Center
Polycystic Ovary Syndrome
Mechanisms of Increased Androgen Production Among Women With Polycystic Ovary Syndrome
Jeffrey Chang MD is conducting a research study to learn more about the increased male hormone levels, otherwise known as androgens, seen in women with polycystic ovary syndrome (PCOS).
- Trial name
- NCT00989781
- Testing
- 3-D Ultrasound, recombinant human chorionic gonadotropin, Recombinant human follicle stimulating hormone
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Anovulation, FHA
FHA: Characterization of Metabolic Status, Brain Circuitry, and Stress-Reactivity
Functional Hypothalamic Amenorrhea (FHA), the spontaneous cessation of the menstrual cycle for at least 6 months after menstrual cyclicity has been established, is a common and reversible form of anovulation not due to…
- Conditions
- Anovulation, FHA, Eumenorrhea, Polycystic Ovary Syndrome
- Trial name
- NCT00453219
- Testing
- Screening evaluation, Meal Response, Blood Collection
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Emory University
Cardiovascular Diseases
Reexamining Her Cardiovascular Risk - Ottawa WomeN's Longitudinal Cohort Study
The full HER CROWN will be a prospective cohort study to propose a novel, women-specific cardiovascular risk score/ algorithm in the prediction of hard cardiovascular outcomes (myocardial infarction, unstable angina, coronary…
- Trial name
- HER-CROWN (NCT05632601)
- Testing
- PET scan
- Where
- Canada
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Ottawa Heart Institute Research Corporation
Polycystic Ovary Syndrome, Insulin Resistance
Insulin Resistance Before and During Pregnancy in Women With Polycystic Ovary Syndrome
The polycystic ovary syndrome (PCOS) affects about 10% of reproductive-age women. Women with PCOS are at a higher risk of gestational diabetes, which may lead to more pregnancy complications.
- Conditions
- Polycystic Ovary Syndrome, Insulin Resistance, Insulin Sensitivity, Obesity
- Trial name
- NCT01475565
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Virginia Commonwealth University
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