Clinical trials: PCOS (Polycystic Ovary Syndrome)
PCOS (Polycystic Ovary Syndrome)
Effect of Drospirenone-Ethinyl Estradiol (20microgram vs 30 Microgram) on Free Androgen Index in PCOS
Combined hormonal contraceptive (CHC) improves androgen parameter in women with PCOS. High-dose CHC increases insulin resistance, whereas low dose CHC has minimal effects on carbohydrate metabolism.
- Trial name
- PCOS FAI CHC (NCT07318337)
- Testing
- Drospirenone Ethinyl Estradiol (20 microgram), Drospirenone Ethinyl Estradiol (30 microgram)
- Where
- Bangladesh
- Volunteers
- 60 people
- Sponsor
- Mst.Sumyara Khatun
Polycystic Ovary Syndrome
Effect of UC Versus EA on Sex Hormones in Obese Infertile Patients With PCOs
The aim of this study is to determine the difference between the effect of Ultrasound Cavitation and Elctroacupuncture on sex hormones in obese infertile patients with poly cystic ovarian syndrome ………………………………………………………………………
- Trial name
- NCT04875312
- Testing
- Ultrasound cavitation in group A, Electro acupuncture in group B
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mohamed Abdel Hamid elgaedy
Polycystic Ovary Syndrome, Urine Albumin \(UAlb\)
Urine Albumin/Creatinine Ratio and Renal Function Differences in Phenotypes of Polycystic Ovary Syndrome.
Since there are different metabolic effects in different phenotypes of polycystic ovary syndrome (PCOS); in this study; the investigators aimed to investigate whether there is a difference between glomerular filtration rate…
- Conditions
- Polycystic Ovary Syndrome, Urine Albumin \(UAlb\), Urine Creatinine \(UCr\), Glomerular Filtration Rate
- Trial name
- NCT07441811
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- Uşak University
Polycystic Ovarian Syndrome (PCOS)
Effects of Wet-Cupping on Polycystic Ovary Syndrome Patients
The goal of this clinical trial is to evaluate whether wet cupping therapy (Hijama) can improve reproductive and metabolic outcomes in women diagnosed with Polycystic Ovary Syndrome (PCOS).
- Trial name
- NCT07169292
- Testing
- Wet-cupping
- Where
- Saudi Arabia
- Volunteers
- 60 people
- Sponsor
- Princess Nourah Bint Abdulrahman University
Polycystic Ovarian Syndrome in Adolescent Females, Obesity (Disorder)
Effects of Glucagon-like Peptide-1 (GLP-1) Agonist in Neuro-reproductive Function in Obese Adolescent Females With Polycystic Ovary Syndrome (PCOS)
The prevalence of childhood obesity in the United States has more than tripled in the past four decades affecting one in every five adolescent girls and is disproportionally higher among racial and/or ethnic minorities.
- Trial name
- NCT07169136
- Testing
- GLP-1 Receptor Agonists
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Nemours Children's Clinic
PCOS (Polycystic Ovary Syndrome), Insulinemic Response
Assessment of Metabolic Changes in Response to Glcuose Intake in Women With Polyendocrine Metabolic Ovarian Syndrome (PMOS)
Polyendocrine metabolic ovarian syndrome (PMOS), previously known as polycystic ovary syndrome (PCOS), is a common endocrine and metabolic condition affecting women of reproductive age.
- Conditions
- PCOS (Polycystic Ovary Syndrome), Insulinemic Response, Overweight (BMI > 25)
- Trial name
- METFLEX (NCT07687264)
- Testing
- Oral Clucose Tolerance Test (oGTT)
- Where
- Switzerland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Polycystic Ovary Syndrome
Treating Obese PCOS Patients With LSG vs. Met
Polycystic ovary syndrome (PCOS) is a common endocrine disorder, with a prevalence of 5% to 15% in premenopausal women. Patients with PCOS presents as abnormal menstruation, ovulation disorders and/or hyperandrogenemia, and often…
- Trial name
- NCT04508634
- Testing
- laparoscopic sleeve gastrectomy, Metformin Pill
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Shanghai 10th People's Hospital
Polycystic Ovary Syndrome, Insulin Resistance
Acupuncture to Treat Insulin Resistance in Women With and Without Polycystic Ovary Syndrome
The central hypothesis is that acupuncture break the vicious circle of androgen excess and reverse insulin resistance and improve health related quality of life and affective symptoms in overweight and obese women with and…
- Trial name
- PCOS-AcupIR (NCT01457209)
- Testing
- Acupuncture
- Where
- Sweden
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Göteborg University
PCOS, Infertility
Glucose Metabolism and Live Birth Outcomes in PCOS
Polycystic ovary syndrome (PCOS) is a common endocrine and reproductive disorder in which insulin resistance (IR) is proposed as a key pathophysiological feature of the disease's symptoms and consequences.
- Conditions
- PCOS, Infertility, Diabetes, PreDiabetes
- Trial name
- NCT04364087
- Testing
- Oral glucose tolerance test
- Where
- Vietnam
- Volunteers
- 1,208 people
- Sponsor
- Mỹ Đức Hospital
Polycystic Ovary Syndrome (PCOS)
Blood Vessel Function in Adolescents and Women With Polycystic Ovary Syndrome
The purpose of this study is to determine if changes in blood vessel health lead to the menstrual irregularities that women with PCOS experience.
- Trial name
- NCT01615562
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Polycystic Ovary Syndrome
Insulin Resistance, Polycystic Ovary Syndrome, and Bone Research Study
The purpose is to investigate the effects of 2 different treatments (drospirenone/ethinyl estradiol versus rosiglitazone) on insulin sensitivity and androgen levels, inflammatory markers, vascular markers and bone development in…
- Trial name
- NCT00640224
- Testing
- rosiglitazone, drospirenone/ethinyl estradiol
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Silva Arslanian
Polycystic Ovary Syndrome
Probiotic Intervention in PCOS
The investigators are conducting a double-blinded randomized controlled trial to determine whether a probiotic mixture is effective in reducing PCOS-related symptoms.
- Trial name
- ProPCO-RCT (NCT04593459)
- Testing
- Probiotic, Metformin Hydrochloride
- Where
- Austria
- Volunteers
- 112 people
- Sponsor
- Medical University of Graz
Polycystic Ovary Syndrome, Anovulation
The Effect of Metformin Added to Clomiphene Citrate on Pregnancy Rates in Hyperandrogenic, Chronic Oligoovulatory or Anovulatory Women
The purpose of our study was to conduct a placebo controlled, double-blind randomized trial in chronic oligoovulatory or anovulatory , hyperandrogenic, infertility patients comparing the effects of adjuvant metformin plus…
- Conditions
- Polycystic Ovary Syndrome, Anovulation, Oligoovulation, Infertility
- Trial name
- NCT00413179
- Testing
- Metformin, Clomiphene citrate
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- 59th Medical Wing
Amenorrhea, Oligomenorrhea
Treatment of Menstrual Cycle Alterations in Adolescents
the aim of the present study is intended to evaluate how treatment with Myo-Inositol and Dioscorea Villosa can help improve menstrual cycle irregularities in adolescents, both with and without PCOS.
- Conditions
- Amenorrhea, Oligomenorrhea, PCOS (Polycystic Ovary Syndrome)
- Trial name
- HP-phD_Adolesc (NCT06800170)
- Testing
- myo-Inositol plus DIoscorea Villosa
- Where
- 2 sites in Georgia, Russia
- Volunteers
- 41 people
- Sponsor
- Lo.Li.Pharma s.r.l
PCOS, NAFLD
Androgens and NAFLD Longitudinal Cohort Study
The researchers want to learn how androgens, a type of sex hormone, might affect nonalcoholic fatty liver (NAFLD) in young women over time.
- Conditions
- PCOS, NAFLD, NASH
- Trial name
- NCT06124261
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- University of California, San Francisco
Polycystic Ovary Syndrome, Infertility
Treatment of Infertility in Women With Polycystic Ovary Syndrome
Polycystic Ovary Syndrome (PCOS) is a common endocrine disorder affecting up to 10% of women. The primary symptoms of PCOS are menstrual irregularities, increased body and facial hair, acne, and infertility.
- Conditions
- Polycystic Ovary Syndrome, Infertility, Pregnancy
- Trial name
- NCT00068861
- Testing
- metformin XR, clomiphene citrate
- Where
- 11 sites in United States
- Volunteers
- 678 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Polycystic Ovary Syndrome, Normal Volunteers
Proteomics & Glyco-Proteomic Analysis of Follicular Fluid
To the best of the investigators knowledge, exhaustive characterization of the low and high abundant proteins and glyco-proteins of the Follicular Fluid (FF) has not yet been achieved.
- Trial name
- NCT01487486
- Testing
- IVF Antagonist Protocol
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Cincinnati
Polycystic Ovary Syndrome, Disorder of Glucose Regulation
Saxagliptin + Metformin Compared to Saxagliptin or Metformin Monotherapy in PCOS Women With Impaired Glucose Homeostasis
The objective of the present proposal is to compare the clinical, endocrine and metabolic effects of therapy with combination saxagliptin and metformin to saxagliptin and metformin monotherapy in women with PCOS and prediabetic…
- Trial name
- BMS-AZPCOS (NCT02022007)
- Testing
- Metformin XR, Saxagliptin, Saxagliptin-Metformin XR
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Woman's
Polycystic Ovary Syndrome, Obstructive Sleep Apnea
Metabolic Study of Women With Polycystic Ovary Syndrome and Sleep Apnea
The purpose of this study is to look at the metabolic (use of energy) and hormonal features of sleep problems in women with polycystic ovary syndrome (PCOS).
- Trial name
- NCT00696111
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Chicago
Polycystic Ovary Syndrome
The Association of Ferrtin and Homocysteine Etc. With RI and MS in Polycystic Ovary Syndrome (PCOS)
The purpose of this study is to study the association of serum ferritin and homocysteine levels with insulin resistance and metabolic syndrome in women with polycystic ovary syndrome The polycystic ovary syndrome (PCOS) is a…
- Trial name
- NCT01600833
- Where
- Taiwan
- Volunteers
- 539 people
- Sponsor
- Taipei Medical University WanFang Hospital
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