Clinical trials: PCOS (Polycystic Ovary Syndrome)
Polycystic Ovary Syndrome, Insulin Resistance
The Effects of Walnuts, Walnut-Oil, Almonds and Fish Oils on Glucose Homeostasis in Polycystic Ovary Syndrome
The purpose of this study is to learn more about the effects of walnuts, walnut-oil, almonds and fish oils on blood sugar and insulin levels in polycystic ovary syndrome (PCOS) patients.
- Trial name
- NCT00579904
- Testing
- walnuts, almonds
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- University of California, Davis
Polycystic Ovary Syndrome
Inositol Treatment in Different Type of PCOS Phenotype
Evaluation of the efficacy of inositol treatment in women with PCOS in relation to the phenotype (according to the Rotterdam Criteria)
- Trial name
- NCT05678114
- Testing
- Myo-inositol
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- Lo.Li.Pharma s.r.l
Polycystic Ovary Syndrome, Infertility
Myo-inositol Therapy on the Dynamics of Embryo Development in Patients Suffering From PCOS Undergoing ICSI Treatment
The purpose of this study is to analyse the activity of myo-inositol on pregnancy rate, embryo development dynamics and oestradiol and progesterone concentration in blood serum and Superoxide Dismutase (SOD) and catalase…
- Trial name
- NCT02385396
- Testing
- Inofolic: myo-inositol and folic acid
- Where
- Poland
- Volunteers
- 217 people
- Sponsor
- Medical University of Lublin
PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries
PCOS and US Cavitation
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women of reproductive age. Women with this syndrome may have infrequent menstrual periods or amenorrhea and excess androgen levels.
- Trial name
- NCT05880550
- Testing
- ultrasound cavitation in addition to aerobic ex, aerobic exercises.
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Polycystic Ovary Syndrome
Myo-Inositol for Ovarian Stimulation and ICSI Outcomes in Women With PCOS
Polycystic ovary syndrome (PCOS) is a common endocrine disorder that may affect ovarian function, insulin sensitivity, and fertility.
- Trial name
- NCT07779850
- Testing
- Myo-Inositol, Folic Acid
- Where
- Egypt
- Volunteers
- 88 people
- Sponsor
- Kafrelsheikh University
Ovulation Induction
Effect of Vitamin D Supplement in Induction of Ovulation in Overweight Women With Polycystic Ovary Syndrome
The aim of this work is to evaluate the effect of vitamin D supplementation in overweight infertile women with PCOs undergoing induction of ovulation.
- Trial name
- NCT03396380
- Testing
- Vitamin D with calcium and clomiphene citrate
- Where
- Egypt
- Volunteers
- 186 people
- Sponsor
- Ain Shams University
Polycystic Ovary Syndrome, Obesity
Two Different Dietary Interventions for Girls With Polycystic Ovary Syndrome
This study was conducted to evaluate the efficacy of the MEtabolic Syndrome REduction in NAvarra (RESMENA) diet versus a control diet based on American Heart Association (AHA) recommendations for the treatment of PCOS in…
- Conditions
- Polycystic Ovary Syndrome, Obesity, Androgen; Hypersecretion, Diet, Healthy
- Trial name
- NCT05768724
- Testing
- intervention diet, control diet
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Gazi University
PCOS
Exogenous Ketone Ester in Women with Polycystic Ovary Syndrome.
Polycystic ovarian syndrome (PCOS) is characterized by elevated androgens such as testosterone. Clinical studies suggest that ketogenic diets lower the levels of androgens.
- Trial name
- NCT05762822
- Testing
- 3-OHB (KE4), water
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- University of Aarhus
Polycystic Ovary Syndrome
Surgical Ovarian Drilling Versus Hormonal Treatment for Infertility Associated to PolyCystic Ovaries Syndrome (PCOS)
PolysCsytic Ovaries Syndrome (PCOS) is the most frequent endocrinopathy. The first stage of infertility treatment is Clomiphene Citrate which leads to 50 % pregnancies.
- Trial name
- PERCING (NCT00378729)
- Testing
- Metformin and FSHr, Ovarian drilling by FERTILOSCOPY
- Where
- France
- Volunteers
- 252 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Polycystic Ovary Syndrome
High Intensity Interval Training or Strength Training in Women With Polycystic Ovary Syndrome
The aim is to investigate whether strength training or high intensity interval training is effective in improving insulin sensitivity, cardiovascular outcomes, body composition and reproductive outcomes in women with Polycystic…
- Trial name
- NCT01919281
- Testing
- strength training, interval training
- Where
- Norway
- Volunteers
- 31 people
- Sponsor
- Norwegian University of Science and Technology
Polycystic Ovary Syndrome
Empagliflozin vs Metformin in PCOS
This a randomised open-label parallel study involving women with polycystic ovary syndrome (PCOS). The patients will be randomised either to metformin 1500mg or empagliflozin 25mg daily for three months.
- Trial name
- NCT03008551
- Testing
- Empagliflozin, Metformin
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Hull University Teaching Hospitals NHS Trust
Polycystic Ovary Syndrome, Endothelial Dysfunction
Metformin+ Drospirenone/ethinylestradiol30µg and Flow-mediated Dilation in Polycystic Ovary Syndrome
The purpose of this study is to assess the effects of ethinylestradiol 30µg-drospirenone combined with metformin and weight loss by means of dietary intervention on the indices of endothelial dysfunction (i.e.
- Trial name
- NCT01459445
- Testing
- Metformin, Ethinylestradiol 30µg-Drospirenone
- Where
- Romania
- Volunteers
- 26 people
- Sponsor
- Iuliu Hatieganu University of Medicine and Pharmacy
Polycystic Ovary Syndrome
Reproductive Endocrinology Oxford Study (RepOx)
This is a prospective observational study that aims to identify the underlying mechanisms of PolyCystic Ovarian Syndrome (PCOS) and associated comorbidities such as subfertility, miscarriage; and pregnancy complications such as…
- Trial name
- RepOx (NCT05177562)
- Testing
- No intervention
- Where
- United Kingdom
- Volunteers
- 1,175 people
- Sponsor
- University of Oxford
PCOS (Polycystic Ovary Syndrome), Puberty
ActiveGirls: Physical Activity, Hormone Health, and Diabetes Risk in Early Adolescence
This study explores how a physical activity program can affect hormone health and diabetes risk in girls ages 8-12 who may be at higher risk.
- Conditions
- PCOS (Polycystic Ovary Syndrome), Puberty, Insulin Resistance, Physical Activity
- Trial name
- NCT07102797
- Testing
- ActiveGirls Physical Activity Program (Full), ActiveGirls Physical Activity Program (Delayed Lower Intensity)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Massachusetts General Hospital
Polycystic Ovary Syndrome
Clinical and Basic Research on the Treatment of Polycystic Ovary Syndrome
Polycystic ovary syndrome is the most common endocrine and metabolic disorder in gynecology. Traditional Chinese medicine has a good clinical effect in the treatment of PCOS.
- Trial name
- NCT04120597
- Testing
- Zishen Qingre Lishi Huayu Granules
- Where
- China
- Volunteers
- 126 people
- Sponsor
- Jiangxi University of Traditional Chinese Medicine
PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries
Effect of Hyperandrogenism on IVF Outcomes in PCOS Patients
Ovulatory dysfunction affects 18 to 25% of infertile women, the most common identifiable condition is polycystic ovarian syndrome (PCOS).
- Trial name
- HIP (NCT05555680)
- Testing
- Ferriman-Gallwey Score
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- Clinique Ovo
Polycystic Ovary Syndrome
Ovary Syndrome for Efficient Diagnosis and Targeted Therapy
OBJECTIVES: 1. Analysis of DNA methyl transferases (DNMT1, DNMT3A and DNMT3B) and Histone deacetylases (HDAC 1,2,3 and SIRTs) polymorphisms (Somatic and germ line variations). 2.
- Trial name
- PCOS-01 (NCT06102629)
- Testing
- laparoscopy / laparotomy, NO INTERVENTION
- Where
- India
- Volunteers
- 200 people
- Sponsor
- Asian Institute of Gastroenterology, India
Polycystic Ovary Syndrome
Activity of Chronic Inflammation in PCOS
Chronic inflammation in polycystic ovary syndrome (PCOS) may be the result of dysregulation of cytokine production (due to insulin resistance, excess visceral fat and hyperandrogenemia), i.e., overproduction of pro-inflammatory…
- Trial name
- NCT06300593
- Testing
- Measurement and comparison of leucocytosis and concentrations of C-reactive protein (CRP), interleukin-1 (IL-1), IL-6, IL-10, Tumor Necrosis Factor (TNF-alpha) in PCOS phenotypes A, B, C and D, Evaluation of the correlation of serum concentrations of selected inflammatory markers (leucocytosis, CRP, IL-1, IL-6, IL-10, TNF-alpha) with metabolic and hormonal parameters
- Where
- Poland
- Volunteers
- 80 people
- Sponsor
- Jagiellonian University
Polycystic Ovary Syndrome
Effect of Exercise on Cardiometabolic Profile in Women With Polycystic Ovary Syndrome
Polycystic Ovary Syndrome (PCOS) is a complex hormonal and metabolic disorder that has been shown to affect women's fertility. It can also share many symptoms with pre-diabetes, and women with PCOS often have an increased risk…
- Trial name
- NCT03678714
- Testing
- Exercise Intervention, Lifestyle Physical Activity
- Where
- United Kingdom
- Volunteers
- 37 people
- Sponsor
- Sheffield Hallam University
Polycystic Ovary Syndrome
Metformin Suspension and Insulin Sensitivity
Metformin is an insulin sensitizing drug routinely used for the treatment of anovulatory patients with polycystic ovary syndrome (PCOS).
- Trial name
- NCT00437333
- Testing
- Metformin cloridrate
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- University Magna Graecia
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