Clinical trials: PCOS (Polycystic Ovary Syndrome)
Polycystic Ovary Syndrome, Obesity
EQW, DAPA, EQW/DAPA, DAPA/MET ER and PHEN/TPM ER in Obese Women With PolycysticOvary Syndrome (PCOS)
This is a randomized, single-blind, parallel 5 treatment group 24-week trial designed to directly compare the therapeutic effects of exenatide once weekly (EQW), dapagliflozin (DAPA), EQW plus DAPA, combined DAPA/metformin…
- Trial name
- NCT02635386
- Testing
- Exenatide once weekly (EQW ), Dapagliflozin (DAPA), EQW plus DAPA
- Where
- United States
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Woman's
Polycystic Ovarian Syndrome, Infertility
Healthy Eating for Reproductive Health (HERHealth)
This study will be a 6-month intervention that is examining how different dietary approached may be useful for women with Polycystic Ovarian Syndrome (PCOS) who are attempting pregnancy, particularly by measuring changes in…
- Conditions
- Polycystic Ovarian Syndrome, Infertility, Obesity, Overweight
- Trial name
- HERHealth (NCT01509066)
- Testing
- Diet
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Polycystic Ovary Syndrome
High Intensity Interval Training in PCOS
Study objective is to determine the effect of High intensity interval training on psychological wellbeing, Anthropometrics and Quality of life in females with Polycystic Ovarian Syndrome
- Trial name
- NCT05348265
- Testing
- Low Intensity steady state training, High intensity interval training
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Riphah International University
Polycystic Ovary Syndrome
PriskA Pilot Study
Background of the study: With a prevalence up to 15%, polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women of reproductive age.
- Trial name
- NCT05785507
- Testing
- PriskA tool
- Where
- Netherlands
- Volunteers
- 150 people
- Sponsor
- Erasmus Medical Center
Polycystic Ovary Syndrome, Dietary Habits
Comparison of Lifestyle Markers Between Women With and Without Polycystic Ovary Syndrome
The purpose of the study is to identify lifestyle factors associated with PCOS and understand how diet and activity levels impact features of PCOS.
- Conditions
- Polycystic Ovary Syndrome, Dietary Habits, Physical Activity
- Trial name
- NCT01859663
- Where
- 3 sites in United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Cornell University
Sterility, Infertility
Myo-Inositol- Based Co-treatment in Women With PCOS Undergoing Assisted Reproductive Technology
This is a prospective comparative randomized controlled study investigating the effect of Myo-Inositol-based co-treatment on oocyte quality measures in women with PCOS.
- Trial name
- NCT03177122
- Testing
- Myo-inositol
- Where
- Lebanon
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Polycystic Ovary Syndrome
Effect of Aerobic Exercise on Polycystic Ovary Syndrome
The development of Polycystic Ovary Syndrome has been linked to chronic low-grade inflammation (PCOS). In this context, the current study looked into the effects of aerobic exercise on IL6, TNF, and C-reactive protein (CRP) in…
- Trial name
- NCT05233514
- Testing
- Aerobic exercise in addition to Metformin treatment
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Polycystic Ovary Syndrome
Myo-inositol Versus Metformin in Obese Women With Polycystic Ovary Syndrome
The aim of this study is to compare the effects of six months treatment of two insulin-lowering therapies on the clinical and endocrine-metabolic parameters in obese women affected by polycystic ovary syndrome.
- Trial name
- NCT01791647
- Testing
- metformin 1500 mg, myoinositol 1500 mg
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Catholic University of the Sacred Heart
Polycystic Ovary Syndrome
The Effects of Folic Acid on Sudanese Women With Polycystic Ovary Syndrome
An open clinical trial
- Trial name
- FolicacidPCOS (NCT03268733)
- Testing
- Folic Acid
- Where
- Sudan
- Volunteers
- 90 people
- Sponsor
- University of Khartoum
Polycystic Ovary Syndrome
Environmental Factors in the Development of Polycystic Ovary Syndrome
Polycystic Ovary Syndrome (PCOS) is manifested as a heterogeneous mixture of clinical and bichemical characteristics that complicate study of its etiology.
- Trial name
- NCT00341731
- Where
- 2 sites in United States
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Polycystic Ovary Syndrome, Infertility, Female
Micronutrient Supplementation in PCO-syndrome
The role of micronutrients in fertility has recently gained increased attention. In women who suffer from polycystic ovary syndrome (PCOS) and infertility, we aim to test the impact of a standardized, multinutrient…
- Conditions
- Polycystic Ovary Syndrome, Infertility, Female, Micronutrient Deficiency
- Trial name
- NCT03306745
- Testing
- Profertil female, Folic acid 400 mg
- Where
- Austria
- Volunteers
- 60 people
- Sponsor
- Medical University of Vienna
Reproductive Age, PCOS (Polycystic Ovary Syndrome)
Pro- and Anti-inflammatory Cytokines in PCOS
The study will involve measurements and comparisons of the concentrations of pro-inflammatory cytokines: IL-6, TNF-α, IL-18, as well as anti-inflammatory cytokine IL-4 in women with polycystic ovary syndrome (PCOS) and insulin…
- Trial name
- NCT06793085
- Testing
- Measurement of interleukin-6 (il-6) concentration in blood serum, Measurement of fasting tumor necrosis factor α (TNF-α) concentration, Measurement of interleukin-18 (il-18) concentration
- Where
- Poland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Jagiellonian University
Polycystic Ovarian Syndrome
The Efficacy and Safety Study of Tung's Acupuncture for Polycystic Ovarian Syndrome
This study evaluates the efficacy and safety in improving ovarian function of polycystic ovarian syndrome in adults. Half of patients will receive Tung's acupuncture therapy, while the other half will receive Diane-35(CPA/EE) as…
- Trial name
- NCT02729545
- Testing
- Tung's acupuncture, Cyproterone acetate/ethinylestradiol (CPA/EE)
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Beijing Hospital of Integrated Traditional Chinese and Western Medicine
PCOS, Insulin Resistance
Effects of Simvastatin and Micronized Trans-resveratrol Treatment on Polycystic Ovary Syndrome (PCOS) Patients
Polycystic ovary syndrome (PCOS) is the most common endocrinopathy affecting women of reproductive age. Hyperandrogenism is the central feature of PCOS.
- Trial name
- NCT02766803
- Testing
- Simvastatin and micronized trans-resveratrol
- Where
- Poland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Poznan University of Medical Sciences
Polycystic Ovary Syndrome
the Effect of Diane-35 Pretreatment on In-vitro Fertilization Outcome for Patients With Polycystic Ovary Syndrome
Polycystic Ovary Syndrome is the most common endocrine disorder in women, is estimated to affect more than 5% of the population and is associated with chronically elevated serum androgen concentrations.Evidence suggests that…
- Trial name
- NCT01752270
- Testing
- Diane-35 pretreatment
- Where
- 2 sites in China
- Volunteers
- 100 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Polycystic Ovary Syndrome
Efficacy of Metformin in PCOS: Metabolic and Hormonal Factors
Hypothesis: Metformin treatment normalises hormone values and metabolic parameters in women with PCOS. Ovulation is restored and bleeding periods become regular.
- Trial name
- NCT00317928
- Testing
- Metformin
- Volunteers
- 50 people
- Sponsor
- Aarhus University Hospital Skejby
Polycystic Ovary Syndrome
OCP vs Metformin for Improvement in Clinical Symptoms and Metabolic Markers in Indian PCOS Women
Objective: To assess effectiveness of ISD (Insulin sensitizing drugs) Vs OCP (Combined E\&P cyproterone acetate) in improving clinical, hormonal and metabolic features of PCOS( polycystic ovary syndrome)women from India.
- Trial name
- OCP (NCT02744131)
- Testing
- Oral contraceptive pill combination of ethyl estradiol and Cyproterone acetate, Metformin 1500mgs per day
- Where
- India
- Volunteers
- 100 people
- Sponsor
- Kar Clinic & Hospital Pvt. Ltd.
Polycystic Ovary Syndrome
Mean Platelet Volume and TXA2 Levels in Patients With Polycystic Ovary Syndrome (PCOS)
Polycystic ovary syndrome (PCOS)is closely associated with insulin resistance and hyperinsulinemia as well as with increased incidence in diabetes, hypertension, dyslipidemia and atherosclerosis.
- Trial name
- NCT01538602
- Where
- Italy
- Sponsor
- AGUNCO Obstetrics and Gynecology Centre
Polycystic Ovary Syndrome, Estro-progestin Drugs
Effect of Two Different Dosages of Ethinyl-estradiol in Association With Drospirenone in Women With Polycystic Ovary Syndrome.
The estrogenic component of estro-progestin (EP) is responsible for a negative impact on the metabolic and lipid assessment in women with polycystic ovary syndrome (PCOS).
- Trial name
- NCT01519401
- Testing
- 3 mg drospirenone and 20 µg ethinyl-estradiol, 3 mg drospirenone and 30 µg ethinyl-estradiol
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Catholic University of the Sacred Heart
Polycystic Ovary Syndrome, Obstructive Sleep Apnea
The Impact of Obstructive Sleep Apnoea in Women With Polycystic Ovary Syndrome.
Women with PCOS and OSA, compared to women with PCOS only, have more severe clinical and biochemical features of PCOS and impaired QoL.
- Trial name
- NCT03065322
- Testing
- To assess risk of OSA
- Where
- United Kingdom
- Volunteers
- 38 people
- Sponsor
- University Hospitals Coventry and Warwickshire NHS Trust
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