Clinical trials: PCOS (Polycystic Ovary Syndrome)
PCOS
Correction of Vitamin D Deficiency and Its Effect on Ovulation Induction in Women With PCOS (VIDEO): A Feasibility RCT
Recently, a special emphasis has recently been directed to the potential role of vitamin D and some regulatory peptides (e.g. adipokines and follistatin) and their associated metabolic roles and genetic factors in the development…
- Trial name
- PCOSD (NCT02656121)
- Testing
- Vitamin D, Ovulatory Agent
- Where
- Egypt
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Polycystic Ovary Syndrome
Adipose Tissue Function and Response to Exercise Training in Women With and Without Polycystic Ovary Syndrome
The primary aim of this trial is to investigate adipose tissue function in women with and without polycystic ovary syndrome (PCOS). PCOS is a common endocrine disorder in young women.
- Trial name
- HIT-FAT (NCT02943291)
- Testing
- 4x4 minutes high intensity interval training, 10x1 minute high intensity interval training
- Where
- 2 sites in Australia, Norway
- Volunteers
- 15 people
- Sponsor
- Norwegian University of Science and Technology
Polycystic Ovary Syndrome, Polycystic Ovary Syndrome (PCOS) Women
Metabolic and Hormonal Parameters in Women With Polyendocrine Metabolic Ovarian Syndrome
Polyendocrine Metabolic Ovarian Syndrome (PMOS) is a common endocrine and metabolic disorder associated with insulin resistance, hyperandrogenism, and an increased risk of long-term metabolic complications.
- Conditions
- Polycystic Ovary Syndrome, Polycystic Ovary Syndrome (PCOS) Women, Fetuin-A, Serum Biomarkers
- Trial name
- PMOS-FR (NCT07844785)
- Testing
- Blood and Saliva Biomarker Assessment
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Istinye University
Polycystic Ovary Syndrome, Metformin
Study of Acupuncture to Control Weight and Improve Pregnancy Rates in Overweight/Obese PCOS Patients
Polycystic ovary syndrome (PCOS) is the most common cause of anovulatory infertility and is characterized by ovulatory dysfunction, increased androgens, and polycystic ovaries.
- Conditions
- Polycystic Ovary Syndrome, Metformin, Acupuncture
- Trial name
- NCT06717087
- Testing
- Acupuncture+lifestyle intervention, Metformin+lifestyle intervention
- Where
- China
- Volunteers
- 92 people
- Sponsor
- RenJi Hospital
Polycystic Ovary Syndrome, Healthy
Vitamin D Treatment, Pharmacogenetics and Glucose Metabolism
Background: Polycystic ovary syndrome (PCOS) is as common as 5-10% of all women in Austria. PCOS women frequently present with metabolic disturbances, hyperandrogenism and infertility. New therapy concepts are warranted.
- Conditions
- Polycystic Ovary Syndrome, Healthy, Vitamin D Deficiency
- Trial name
- NCT01721915
- Testing
- Vitamin D supplementation
- Where
- Austria
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Polycystic Ovary Syndrome, Insulin Resistance
Is There Association Between Vitamin D Levels And Insulin Resistance In Polycystic Ovary Syndrome?
The primary aim of the current study is to clarify whether serum vitamin D levels [25(OH)D3] have a temporal association with insulin resistance and/or insulin sensitivity in PCOS women versus healthy ones.
- Conditions
- Polycystic Ovary Syndrome, Insulin Resistance, Vitamin D Deficiency
- Trial name
- NCT02803476
- Where
- Egypt
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Polycystic Ovary Syndrome
Exenatide and Metformin Therapy in Overweight Women With PCOS
Current research has shown that the use of diabetes management practices aimed at reducing insulin resistance and hyperinsulinemia (such as weight reduction and the administration of oral antidiabetic drugs) in women with PCOS…
- Trial name
- NCT00344851
- Testing
- metformin, exenatide or combined (metformin & exenatide )
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Metabolic Center of Louisiana Research Foundation
Polycystic Ovary Syndrome IVF
OVERWEIGHT AND OBESITY ADVERSELY AFFECT IVF OUTCOMES IN WOMEN WITH PCOS
The effect of overweight and obesity on IVF outcomes is still questionable. The purpose of this study was to determine if overweight/obesity in women with PCOS were associated with an adverse IVF outcome compared to those with…
- Trial name
- NCT03120286
- Volunteers
- 146 people
- Sponsor
- Assiut University
Polycystic Ovarian Syndrome (PCOS), Patients Sensitive to Exogenous Gonadotropins
In Vitro Maturation (IVM) of Human Oocytes
We hypothesize that the combination of natural cycle IVF or low dose gonadotropin injection combined with In Vitro Maturation (IVM) (Natural IVF/IVM) is a viable option for a selected population of infertility patients who cannot…
- Conditions
- Polycystic Ovarian Syndrome (PCOS), Patients Sensitive to Exogenous Gonadotropins, Ovarian Hyper Stimulation Syndrome (OHSS)
- Trial name
- IVM (NCT01843569)
- Testing
- In Vitro maturation
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Northwell Health
Polycystic Ovarian Syndrome (PCOS)
Polycystic Ovarian Syndrome (PCOS) Biomarker Evaluation Study
The purpose of the study is to validate recently identified biomarkers for the identification of PCOS in adolecent and young adult women.
- Trial name
- PHOEBE (NCT06642831)
- Where
- Germany
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- University Hospital Erlangen
Interpersonal Psychotherapy, Polycystic Ovary Syndrome
Interpersonal Psychotherapy in Adolescents With Polycystic Ovary Syndrome
The main purpose of this study is to find out whether taking part in a group-based interpersonal psychotherapy (IPT) program designed to improve mood and lessen stress in girls with PCOS will improve depression, unhealthy eating…
- Trial name
- IPAP (NCT06056453)
- Testing
- Interpersonal Psychotherapy
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Polycystic Ovary Syndrome
Effects of Drospirenone-ethinylestradiol and/or NOMAC-valerate Estradiol on Cardiovascular Risk in Women With Polycystic Ovary Syndrome
Polycystic ovary syndrome (PCOS) is often associated with pathological conditions, such as insulin resistance (IR), type 2 diabetes (DM2), obesity and it has potentially increased risk for cardiovascular disease (CVD).
- Trial name
- NCT01603745
- Testing
- Zoely, Yasmin
- Where
- Italy
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Catholic University of the Sacred Heart
Polycystic Ovary Syndrome
Evaluation of Serum Scube-1 Scube-2 and Scube-3 Levels in Patients With Polikistik Over Syndrome ,
The aim of this study is to investigate serum SCUBE-1 and SCUBE-3 levels in PCOS and non-PCOS cases compared with non-PCOS healthy controls with similar age and body mass index
- Trial name
- NCT03765905
- Testing
- study
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
Polycystic Ovary Syndrome, Glucose Intolerance
Glucose Metabolism in Different PCOS Phenotypes
In the present study glucose metabolism and ectopic lipids in the liver, heart and muscle were investigated in women with the polycystic ovary syndrome (PCOS) and in healthy control subjects.
- Conditions
- Polycystic Ovary Syndrome, Glucose Intolerance, Liver Fat, Glucose Metabolism Disorders
- Trial name
- NCT03204461
- Testing
- Oral glucose tolerance test (OGTT), 1H-magnetic resonance spectroscopy
- Where
- Austria
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
PCOS, Obesity
PDE-4 Inhibitor Roflumilast and Polycystic Ovary Syndrome
The purpose of this study was to determine whether combined treatment with phosphodiesterase-4 (PDE-4) inhibitor roflumilast and metformin is more effective than metformin as monotherapy in the treatment of obese women with…
- Trial name
- NCT02037672
- Testing
- metformin, metformin and roflumilast
- Where
- Slovenia
- Volunteers
- 36 people
- Sponsor
- University Medical Centre Ljubljana
Polycystic Ovary Syndrome
Metformin in Pregnant PCOS Women
To investigate the effect of metformin on pregnancy complications and pregnancy outcome in the II. and III. trimester of pregnancy in women with polycystic ovary syndrome.
- Trial name
- PregMet (NCT00159536)
- Testing
- Metformin
- Where
- 10 sites in Norway
- Volunteers
- 257 people
- Sponsor
- Norwegian University of Science and Technology
Infertility, Polycystic Ovarian Syndrome
Endometrial Scratching During Laproscopic Ovarian Drilling in Subfertile PCOS Women
Laparoscopic Ovarian Drilling is a valid procedure for infertile anovulatory women with polycystic ovarian syndrome who failed to get pregnant or to ovulate with ovulation induction medications as clomiphene citrate or exogenous…
- Trial name
- ESLOD (NCT02140398)
- Testing
- Endometrial Currettage
- Where
- Egypt
- Volunteers
- 500 people
- Sponsor
- Mansoura University
Polycystic Ovary Syndrome
Study of Brain Function in Women With Insulin Resistant Polycystic Ovary Syndrome
The purpose of this study is to evaluate the effects of insulin resistance on brain function in women with Polycystic Ovary Syndrome (PCOS).
- Trial name
- NCT00670800
- Testing
- Metformin
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Polycystic Ovary Syndrome
Semaglutide vs Metformin in Polycystic Ovary Syndrome (PCOS)
The goal of this clinical trial is to compare the effect of Semaglutide and metformin on weight loss in obese women with Polycystic Ovarian Syndrome (PCOS) over a 28-week treatment period.
- Trial name
- NCT05646199
- Testing
- Metformin, Semaglutide Injectable Product
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- University of Hull
Polycystic Ovary Syndrome
Study of the Safety and Efficacy of Elagolix in Women With Polycystic Ovary Syndrome
This study will assess the potential impact of elagolix on disordered pituitary and ovarian hormones in women with polycystic ovary syndrome (PCOS).
- Trial name
- NCT03951077
- Testing
- Elagolix
- Where
- 54 sites in United States, Puerto Rico
- Volunteers
- 118 people
- Sponsor
- AbbVie
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