Clinical trials: PCOS (Polycystic Ovary Syndrome)
Polycystic Ovary Syndrome
Metformin Administration in Infertile Anovulatory PCOS Patients
In a recent prospective study evaluating the efficacy of 1700 mg/day metformin as first-line approach for infertile anovulatory patients with PCOS, we identified predictors for metformin efficacy.
- Trial name
- NCT00501787
- Testing
- Metformin
- Where
- Italy
- Sponsor
- University Magna Graecia
PCOS, Vitamin D
Effect of Vitamin D Supplementation on Testosterone Level in Women With Polycystic Ovary Syndrome
The goal of this randomized, double blind, placebo-controlled clinical trial is to learn about, the effect of low dose vitamin D supplementation compares with placebo-controlled group on testosterone level in women with…
- Trial name
- NCT06101147
- Testing
- Vitamin D3
- Where
- Bangladesh
- Volunteers
- 66 people
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Polycystic Ovary Syndrome
Taste Function and Eating Habits in Polycystic Ovary Syndrome
This study evaluates taste function and eating habits in patients with PCOS compared to healthy women and before and after oral contraceptive use.
- Trial name
- NCT04238078
- Testing
- Contraceptive
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
PCOS
Unilateral Laparoscopic Diathermy Adjusted to Ovarian Volume
The objective of our study was to compare the efficiency of the right ULOD using thermal doses adjusted to ovarian volume (60 J/cm3) with the BLOD method at constant dose and to assess treatment efficiency.
- Trial name
- NCT01833949
- Testing
- Unilateral laparoscopic drilling, Bilateral laparoscopic drilling
- Where
- Croatia
- Volunteers
- 96 people
- Sponsor
- KBC Split
Polycystic Ovary Syndrome, Metabolic Syndrome
Study of the Effect of a Nutritional Supplement on Microbiota, Metabolic Control, Inflammatory Profile, and Quality of Life in Patients With Polycystic Ovary Syndrome.
Polycystic Ovary Syndrome (PCOS) is a complex endocrine-metabolic disorder characterized by elevated androgen levels due to ovarian overproduction.
- Trial name
- NCT06551285
- Testing
- Ovapro (Lifepro)
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Celia Bañuls
Poly Cystic Ovary Syndrome
Evaluation of the Effects of Diosmin/Hespiridin Combination on the Clinical Outcomes in Patients With Polycystic Ovary Syndrome
Polycystic ovary syndrome (PCOS) is one of the most prevalent disorders worldwide. Insulin resistance, inflammation and disturbance in sex hormone levels are the main contributing factors of this disease.The majority of studies…
- Trial name
- NCT06083935
- Testing
- Daflon, Combined oral contraceptive, Metformin
- Volunteers
- 120 people
- Sponsor
- Ain Shams University
Obesity, Polycystic Ovary Syndrome
Heat Therapy and Cardiometabolic Health in Obese Women
Traditional medical treatments are often based on research done exclusively in males, and recent research efforts in the physiology community have highlighted critical sex differences in disease presentation and progression.
- Conditions
- Obesity, Polycystic Ovary Syndrome, Prehypertension, PreDiabetes
- Trial name
- CMH (NCT03644524)
- Testing
- Heat therapy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Oregon
Polycystic Ovary Syndrome, Infertility, Female
GnRH Agonist Plus Hormone Replacement Therapy vs Hormone Replacement Therapy on IVF Outcomes
The study is conducted at Arash Women's Hospital on all women undergoing the frozen embryo transfer cycle. Patients who signed informed consent will be randomly divided into two groups.
- Trial name
- NCT05189873
- Testing
- Long GnRH agonist + HRT, HRT
- Where
- Iran
- Volunteers
- 128 people
- Sponsor
- Tehran University of Medical Sciences
Polycystic Ovarian Syndrome
Flaxseed Lignan (Brevail)
PCOS is a disorder which is characterized by hyperandrogenism (high serum male hormone levels), ovulatory dysfunction, and polycystic ovaries (multiple follicles-over 12- in the ovary).
- Trial name
- NCT01396369
- Testing
- Birth control, Birth control plus Brevail
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Kansas Medical Center
Polycystic Ovarian Syndrome, Insulin Resistance
Effect of Whole Body Vibration on Insulin Resistance in Females With Polycystic Ovarian Syndrome
The purpose of this study is to investigate the effect of whole body vibration on insulin resistance in females with polycystic ovarian syndrome
- Trial name
- WBV (NCT05215223)
- Testing
- whole body vibration, Treadmill
- Where
- Egypt
- Volunteers
- 46 people
- Sponsor
- Cairo University
Anovulation
Study of Mechanisms of Anovulation in Polycystic Ovary Syndrome
We previously hypothesized that the excess of Anti-Mullerian Hormone (AMH) at the level of ovarian selectable follicles could be involved in the follicular arrest of Polycystic Ovary Syndrome (PCOS), mainly through inhibition of…
- Trial name
- SOPK (NCT00492882)
- Testing
- usual administration of exogenous recombinant FSH
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Lille
PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries, Depression, Anxiety
Research on Risk Factors and Interventions of Polycystic Ovary Syndrome Complicated With Depression and Anxiety
The current study intends to establish a prediction method and evaluation system for polycystic ovary syndrome (PCOS) complicated with affective disorder, such as depression and anxiety, through the epidemiological investigation.
- Trial name
- PCOS (NCT04984070)
- Testing
- Oral Contraceptives, Combined, Metformin Pill, lifestyle intervention
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Fudan University
Polycystic Ovaries
Phytoestrogens as an Alternative to Estradiol in Ovulation Induction in PCOS
Prospective study conducted on 150 women with polycystic ovarian syndrome (PCOS) were randomly divided into 3 groups: group I (50 women) received clomiphene citrate (CC) only 50 mg orally every 8 hours started from cycle day 3…
- Trial name
- PCOS (NCT02352597)
- Testing
- phytoestrogen, estradiol valerate, clomiphene citrate
- Volunteers
- 150 people
- Sponsor
- Cairo University
Atherosclerosis, Cardiovascular Diseases
Risk of Coronary Heart Disease in Women With Polycystic Ovary Syndrome
To investigate whether women with Polycystic Ovary syndrome (PCOS) have evidence of an increased prevalence rate of subclinical atherosclerosis as measured by the presence of plaque, increased intima-medial carotid artery wall…
- Conditions
- Atherosclerosis, Cardiovascular Diseases, Heart Diseases, Carotid Artery Diseases
- Trial name
- NCT00005459
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Polycystic Ovary Syndrome
A Trial of Lipitor (Atorvastatin) for the Treatment of Polycystic Ovary Syndrome (PCOS) in Women With Elevated Low-density Lipoprotein (LDL) Cholesterol
The purpose of this study is to determine the efficacy of Lipitor (Atorvastatin) for the treatment of PCOS with elevated LDL cholesterol.
- Trial name
- NCT00529542
- Testing
- Lipitor
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Milton S. Hershey Medical Center
Pregnancy Complications, Delivery Complications
CoPPer Study - Complications of Polycystic Ovary Syndrome (PCOS) Pregnancy: Evaluating Risk
The CoPPer study is a follow-up study of women diagnosed with Polycystic Ovary Syndrome (PCOS). Women will be included pre-conceptional and followed-up until after delivery.
- Conditions
- Pregnancy Complications, Delivery Complications, Neonatal Complications
- Trial name
- CoPPer (NCT00821379)
- Where
- Netherlands
- Volunteers
- 300 people
- Sponsor
- UMC Utrecht
Polycystic Ovary Syndrome
Serum Endocan Levels in Polycystic Ovary Syndrome
In this study the investigators aimed to investigate whether there is a relation between polycystic ovary syndrome and serum endocan levels.
- Trial name
- NCT03019679
- Where
- Turkey (Türkiye)
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
PCOS GnRH Antagonist and GnRH Agonist IVF/ICSI Cycles, IVF Outcomes
Effect of Estradiol Pretreatment on Follicular Synchronization and IVF Outcomes in Women With Polycystic Ovary Syndrome Undergoing ICSI Using GnRH Antagonist Protocol
This randomized clinical trial included 60 infertile women diagnosed with PCOS undergoing ICSI cycles using a GnRH antagonist protocol.
- Trial name
- NCT07727863
- Testing
- GnRH Antagonist Protocol, Estradiol Valerate 4mg
- Where
- Egypt
- Volunteers
- 61 people
- Sponsor
- Cairo University
Polycystic Ovary Syndrome
Heritability of Polycystic Ovary Syndrome: Role of Antimullerian Hormone, Steroids and Leptin
Polycystic ovary syndrome (PCOS) is the most common cause of ovulation disorders and affects 10 to 15% of women. Despite its frequency, its physiopathology remains unknown.
- Trial name
- HERITOPK (NCT03483792)
- Testing
- Plasma dosage, placental biopsy
- Where
- France
- Volunteers
- 58 people
- Sponsor
- University Hospital, Lille
Polycystic Ovarian Syndrome, Insulin Resistance
LNK in Polycystic Ovary Syndrome With Insulin Resistance
Insulin resistance (IR) is an important pathological feature of polycystic ovary syndrome (PCOS), with an incidence rate of up to 85%, which seriously affects the patient's fertility, quality of life, and offspring health, but…
- Trial name
- NCT05146063
- Testing
- Take the patient's subcutaneous fat tissue to detect the expression of LNK
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
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