Clinical trials: PCT
Small Bowel Obstruction
A Procalcitonin-based Algorithm in Adhesion-related Small Bowel Obstruction
Adhesion-related small bowel obstruction is a common digestive emergency that can be managed either conservatively or surgically.
- Trial name
- ALPROC (NCT03905239)
- Testing
- algorithm
- Where
- France
- Volunteers
- 488 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Inhalation Pneumonia
PROcalcitonin Pneumonia / Pneumonitis Associated With ASPIration
There is actually no consensus in place defining for which patients with suspected inhalation pneumonia antibiotic treatment should be initiated and what the duration of this antibiotic treatment should be.
- Trial name
- PROPASPI (NCT02862314)
- Testing
- Blood sample
- Where
- France
- Volunteers
- 167 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Community Acquired Pneumonia (CAP), Hospital Acquired Pneumonia
Pneumonia Pathogens' Virulence Factors, Patient Inflammatory Markers, and Their Associations With Outcomes
The study aims to evaluate pneumonia symptoms using physical examinations, radiological and laboratory tests, and prognostic scales such as the Pneumonia Severity Index (PSI) and CURB65.
- Trial name
- Pneumonia-1 (NCT07011433)
- Testing
- Inflammatory Biomarker Evaluation
- Where
- Lithuania
- Volunteers
- 300 people
- Sponsor
- Ruta Nutautiene
NAFLD, Type 2 Diabetes
Study Visceral Adipose Tissue and Liver Stifness in a Retrospective Cohort of Diabetes Mellitus Patients
Non Alcoholic Fatty Liver Disease (NAFLD) is an emergent disease worldwide, and soon the leading cause of hepatic transplant in the USA.
- Trial name
- NCT04493814
- Where
- France
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Nasopharyngeal Carcinoma (NPC)
Prognostic Value of TIL in Nasopharyngeal Carcinoma
Our center plans to conduct a prospective, multicenter, observational study aimed at observing the percentage of TIL infiltration calculated using deep learning methods based on digital pathological images, and analyzing its…
- Trial name
- NCT06763640
- Where
- China
- Volunteers
- 216 people
- Sponsor
- Jiangxi Provincial Cancer Hospital
Adult Acute Lymphoblastic Leukemia
Description and Prognostic Evaluation of Four Biological Parameters of Blast Cells in Adult Acute Lymphoblastic Leukemia
Adult acute lymphoblastic leukemia treatment approaches relie on risk stratification, including cytogenetics. We want to study at diagnosis several blast cells parameters on frozen samples of GRAALL protocols enrolled patients…
- Trial name
- NCT00188084
- Testing
- DNA Index, S-Phase%, CD45 expression
- Where
- France
- Volunteers
- 400 people
- Sponsor
- University Hospital, Angers
NAFLD, Obesity
Influence of a Mediterranean Diet Combined With a Physical Activity Intervention, on NAFLD and Inflammation Parameters.
The study in question is an interventional study with nutritional intervention. The aim of the study is to evaluate whether the adoption of two different models of Mediterranean Diet, based on the different percentage of…
- Conditions
- NAFLD, Obesity, IBS
- Trial name
- NAFLD-POS5 (NCT06275906)
- Testing
- Mediterranean diet and moderate intensity physical exercise (outdoor walking).
- Where
- Italy
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis
Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome, Blasts 5 Percent or More of Bone Marrow Nucleated Cells
EphB4-HSA Fusion Protein and Cytarabine /or Liposomal Vincristine in Patients With Recurrent or Refractory Acute Leukemia
This phase I trial studies the side effects and best dose of recombinant EphB4-HSA fusion protein when given together with cytarabine or vincristine liposomal in treating participants with acute leukemia that has come back or has…
- Conditions
- Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome, Blasts 5 Percent or More of Bone Marrow Nucleated Cells, Myelodysplastic/Myeloproliferative Neoplasm, Philadelphia Chromosome Positive
- Trial name
- NCT03519984
- Testing
- Cytarabine, Laboratory Biomarker Analysis, Recombinant EphB4-HSA Fusion Protein
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of Southern California
Sepsis
PROcalcitonin to SHORTen Antibiotics Duration in PEDiatricICU Patients (ProShort-Ped) Trial
The purpose of this study is to give conclusive evidence on whether serial PCT (Procalcitonin) measurements can facilitate individual decision-making and shorten antibiotic treatment duration in patients with sepsis in the…
- Trial name
- ProShort-Ped (NCT01652404)
- Testing
- Procalcitonin-guided treatment, Conventional treatment
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Hunan Children's Hospital
Music Exposure, NoMusic - Control
Effects of Music and Vibration on Morning Muscle Strength and Cognitive Measures in Males
Athletes often compete in the morning when they are biologically weaker; normally in competition heats or quarterfinals to qualify for the finals scheduled in the evening.
- Conditions
- Music Exposure, NoMusic - Control, Music Plus 15 Percent Tempo, Whole Body Vibration
- Trial name
- NCT07558408
- Testing
- Original Music, Music intervention, Control
- Where
- United Kingdom
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Liverpool John Moores University
Covid19
Study to Find the Percentage of Cases Retaining COVID-19 IgG Antibodies 45-65 After They Have Tested Positive
As a serosurveillance measure asymptomatic employees of an industrial workforce Jamshedpur (India) were tested for COVID-19 IgG antibodies.
- Trial name
- NCT04605952
- Testing
- Repeat SARS-CoV-2 IgG antibodies at 45-65 days
- Where
- India
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- Tata Main Hospital
Aggressive Non-Hodgkin Lymphoma, Blasts Under 5 Percent of Bone Marrow Nucleated Cells
Donor Atorvastatin Treatment in Preventing Severe Acute GVHD After Nonmyeloablative Peripheral Blood Stem Cell Transplant in Patients With Hematological Malignancies
This phase II trial studies how well donor atorvastatin treatment works in preventing severe graft-versus-host disease (GVHD) after nonmyeloablative peripheral blood stem cell (PBSC) transplant in patients with hematological…
- Conditions
- Aggressive Non-Hodgkin Lymphoma, Blasts Under 5 Percent of Bone Marrow Nucleated Cells, Chronic Lymphocytic Leukemia, Loss of Chromosome 17p
- Trial name
- NCT01527045
- Testing
- Atorvastatin Calcium, Cyclosporine, Fludarabine Phosphate
- Where
- 2 sites in United States
- Volunteers
- 47 people
- Sponsor
- Fred Hutchinson Cancer Center
Respiratory Tract Infections
Procalcitonin Guided Antibiotic Use in Acute Respiratory Tract Infections (PARTI)-Study
Acute respiratory tract infections (ARTI) are among the most frequent reasons for seeking medical attention in primary care. Although from predominantly viral origin, ARTIs are the most important condition for the prescription of…
- Trial name
- NCT00099840
- Testing
- Procalcitonin guided antibiotic therapy
- Where
- Switzerland
- Volunteers
- 400 people
- Sponsor
- University Hospital, Basel, Switzerland
Polycystic Ovary Syndrome, Non-Alcoholic Fatty Liver Disease
NAFLD in Adolescents and Young Adults With PCOS
This project focuses on an at-risk adolescent and young adult population who may gain long-term health benefits from detection of risk factors at a young age.
- Conditions
- Polycystic Ovary Syndrome, Non-Alcoholic Fatty Liver Disease, Metabolic Syndrome
- Trial name
- NCT02506946
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Columbia University
Acute Respiratory Distress Syndrome (ARDS), Mechanical Ventilation
Validation of the Percentage of Alveolar Fibrocyte as Biomarker During ARDS
Fibrocyte is a monocyte sub-population involved in fibroproliferation/repair processes and associated with outcome in different diseases.
- Trial name
- IFRA2 (NCT01854424)
- Testing
- Bronchoalveolar lavage (BAL) before day 2 , between days 5-7 and days 10-14 of evolution.
- Where
- France
- Volunteers
- 84 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Infertility (IVF Patients), BMI
BMI Versus Body Fat Percentage - Which is the Better Predictor of Fertility Outcomes in IVF Cycles?
The goal of this prospective observational cohort study is to evaluate whether body composition measured using bioelectrical impedance analysis (BIA) (including measures of body fat% and visceral fat) serve as a better predictor…
- Conditions
- Infertility (IVF Patients), BMI, Bioelectrical Impedance Analysis, IVF Outcomes
- Trial name
- NCT07765368
- Testing
- Measurement of BIA (Body Fat and Visceral Fat Percentage)
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- IWK Health Centre
Percentage of Change in ONSD During Anesthesia With Sevoflurane Versus Propofol in Two Groups of Patients
Sevoflurane Versus Propofol on Optic Nerve Sheath Diameter During Anesthesia in Steep Trendelenburg Position
We will prospectively compare change in ONSD during anesthesia with sevoflurane-only versus anesthesia with propofol-only in two groups of patients undergoing urologic and gynecologic surgery in the steep Trendelenburg position.
- Trial name
- NCT04289090
- Testing
- Sevoflurane Inhalant Product, Propofol 10 MG/ML
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- State University of New York - Downstate Medical Center
Incontinence, Enuresis
Toilet Training Toddlers and Preschoolers
The investigators are interested in determining those procedures that prove to be most efficient and effective in facilitating continence (i.e., "dry pants" or the absence of soiled undergarments), appropriate eliminations (i.e.…
- Trial name
- NCT01747343
- Testing
- Underwear/Differential Reinforcement
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- University of Kansas
Tracheotomy
Impact of Tracheotomy on Procalcitonin
Procalcitonin (PCT) is a reliable biomarker of infection and sepsis. The investigators aimed to determine whether tracheotomy influences PCT concentrations in patients without sepsis, and to assess whether operative duration and…
- Trial name
- NCT02406079
- Testing
- tracheotomy
- Volunteers
- 1 people
- Sponsor
- First People's Hospital of Chenzhou