Clinical trials: PERIPHERAL VASCULAR DISEASE
Peripheral Artery Disease, Intermittent Claudication
Acute Cardiovascular Responses and Chronic Adaptations of Strength Exercise in Intermittent Claudication Patients
The aim of this study was to analyze the effects of resistance exercise and training on cardiovascular function of peripheral artery disease patients.
- Trial name
- NCT02778568
- Testing
- Resistance training, Control
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- University of Pernambuco
Chronic Limb Threatening Ischemia, Infrapopliteal Arterial Occlusive Disease
Revascularization of Single Vesrus Multiple Infrapopliteal Vessels in Chronic Limb Threatening Ischemia
This interventional prospective study aims to assess the effectiveness of single vessel versus multiple vessel infrapopliteal angioplasty in patients with chronic threatening limb ischemia .
- Trial name
- NCT07068789
- Testing
- balloon angioplasty
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Sohag University
Raynaud's Disease
Safety and Efficacy of Pletal(Cilostazol) for the Treatment of Juvenile Primary and Secondary Raynaud's Phenomenon
Juvenile primary Raynaud's (ray-knows) Phenomenon is a disorder of the blood vessels in the fingers and sometimes can affect the toes, nose, or ears.
- Trial name
- NCT00048763
- Testing
- Pletal
- Where
- 18 sites in United States
- Volunteers
- 75 people
- Sponsor
- Otsuka America Pharmaceutical
Brain and Central Nervous System Tumors, Neuroblastoma
Radiolabeled Monoclonal Antibody Therapy After Radiation Therapy in Treating Patients With Primary Brain Tumors
RATIONALE: Monoclonal antibodies can locate tumor cells and deliver tumor-killing substances, such as radioactive iodine, to them without harming normal cells.
- Trial name
- NCT00003484
- Testing
- carmustine, irinotecan hydrochloride, surgical procedure
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Darell D. Bigner, MD, PhD
Peripheral Arterial Disease
The Effect of Thermal Blanket After Peripheral Artery Surgery
Peripheral arterial disease is one of the most common clinical conditions associated with cardiovascular morbidity and increased mortality, requiring exercise, antiaggregant and surgical revascularization therapy.
- Trial name
- NCT06310928
- Testing
- Thermal Blanket
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Chronic Kidney Disease Stage 3 and 4, Peripheral Artery Disease (PAD)
Exercise Activity to Improve Mobility in Patients With CKD and PAD
People affected by chronic kidney disease and concomitant diagnosed peripheral artery disease at intermediate stages, without contraindications to exercise therapy will be invited to participate in the study.
- Trial name
- EXACT-CKDPAD (NCT06621264)
- Testing
- EXERCISE TRAINING WITH OR WITHOUT MEDICATION, Control (Standard treatment)
- Where
- 3 sites in Italy
- Volunteers
- 124 people
- Sponsor
- University Hospital of Ferrara
Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm
Peripheral Stem Cell Transplantation in Treating Patients With Multiple Myeloma or Other B-cell Cancers
RATIONALE: Peripheral stem cell transplantation may allow doctors to give higher doses of chemotherapy drugs and kill more cancer cells.
- Trial name
- NCT00003163
- Testing
- filgrastim, sargramostim, cyclophosphamide
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Medical College of Wisconsin
Peripheral Arterial Disease
Validation of a Correction Factor for Measurement of an Accurate Ankle-Brachial Index in the Seated Position
The purpose of this study is to test a correction factor which would allow ankle brachial indexes taken in the seated position to accurately predict an ankle brachial index taken in the supine position.
- Trial name
- NCT00452309
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- The Cleveland Clinic
Myeloma Multiple
The Risk Stratification in Patients With Multiple Myeloma Based on Fluorescence Flow Cytometry Quantitative Determination of the Circulating Plasma Cells in the Peripheral Blood
The main aim of this study is to evaluate the effectiveness of the clinical application of the XN-1000/20 hematology analyzer for risk stratification in patients with multiple myeloma based on the number of detected plasma cells…
- Trial name
- NCT04242121
- Testing
- fluorescence flow cytometry
- Where
- Russia
- Volunteers
- 24 people
- Sponsor
- Ivan S Moiseev
Peripheral Arterial Disease, Iliac Artery Stenosis
SOLARIS Peripheral PMCF Trial
The objective of this clinical investigation is to evaluate, in a controlled setting, the long-term (up to 12 months) safety and efficacy of the Solaris Vascular Stent Graft (Scitech) in clinical settings when used according to…
- Conditions
- Peripheral Arterial Disease, Iliac Artery Stenosis, Common Femoral Artery Stenosis
- Trial name
- NCT04299906
- Testing
- Solaris Vascular Stent Graft
- Where
- 10 sites in Germany, Italy and 1 more
- Volunteers
- 70 people
- Sponsor
- Dr. Sabrina Overhagen
Cardiogenic Shock
CARDSUP - SWISS Circulatory Support Registry
The project's main goal is to collect baseline clinical and procedural data as well as to assess clinical outcomes for all patients undergoing ECMO or Impella implantation at all included sites.
- Trial name
- CARDSUP (NCT04117230)
- Where
- 5 sites in Switzerland
- Volunteers
- 1,500 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Critical Limb Ischemia, Arterial Occlusive Disease
Safety Study of Adult Stem Cells to Treat Patients With Severe Leg Artery Disease
Peripheral artery disease (PAD) due to leg artery blockages can result in painful leg muscles, skin ulcers and infection due to poor blood flow. In severe forms, the only treatment may be amputation.
- Conditions
- Critical Limb Ischemia, Arterial Occlusive Disease, Vascular Diseases
- Trial name
- SCRIPT-CLI (NCT00913900)
- Testing
- autologous CD133+ cells
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Wisconsin, Madison
CKD, PAD
lncRNAs as a Biomarker to Assess the Therapeutic Impact of Oral Absorbent ± Probiotics in CKD Patients With PAD
Participants with chronic kidney disease (CKD) are at a higher risk of developing atherosclerotic peripheral artery disease (PAD).
- Trial name
- NCT04788914
- Testing
- Active bamboo charcoal± probiotics
- Where
- Taiwan
- Volunteers
- 180 people
- Sponsor
- National Taiwan University Hospital
Diabetic Foot, Gangrene; Limb
MetaMet: Bone Cutter Versus Bone Saw for Ray Amputation
Toe amputation is a commonly performed operation for infection and/or ischaemia (tissue death due to lack of blood flow). However, a large number of patients having this surgery ultimately require further amputation due to poor…
- Conditions
- Diabetic Foot, Gangrene; Limb, Wound Infection, Wound Healing Delayed
- Trial name
- MetaMet (NCT05804565)
- Testing
- Bone Saw, Bone Cutter
- Where
- Ireland
- Volunteers
- 40 people
- Sponsor
- University College Hospital Galway
Critical Limb Ischemia
Effect of Evolocumab in Patients With Critical Limb Ischemia (Evol-CLI)
Critical limb ischemia (CLI), is the most severe form of peripheral arterial disease (PAD), and clinically is characterized by pain at rest or non-healing ulcers of the lower extremities.
- Trial name
- Evol-CLI (NCT04306471)
- Testing
- Evolocumab 140mg/mL Injector 1milliliter (mL) Pen x 3 for a monthly dose of 420 mg for 12 months.
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Leonardo Clavijo
Diabetic Foot Ulcer, Peripheral Arterial Disease
A Non-significant Risk Clinical Study of Therapeutic Ultrasound for Patients With Diabetic Foot Ulcers.
This study is evaluating whether a therapeutic ultrasound device can improve blood flow to the leg with diabetic foot ulcer (DFU).
- Conditions
- Diabetic Foot Ulcer, Peripheral Arterial Disease, Wound; Foot
- Trial name
- Dulcet (NCT05145439)
- Testing
- VibratoSleeve Therapeutic Ultrasound Device
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Vibrato Medical, Inc.
Peripheral Arterial Disease
Cardiac Positioning System in Peripheral Angioplasty Procedure.
This clinical investigation is intended to evaluate the ability of a magnetic cardiac positioning system to decrease medical radiation exposure on a peripheral angioplasty procedure in patients with a peripheral artery stenosis.
- Trial name
- MDG-Periph (NCT03585387)
- Testing
- Navigation
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- Abbott Medical Devices
Peripheral Arterial Disease
BioMimics 3D Stent Clinical Investigation: The Mimics Study
Primary purpose of the Mimics Study is to evaluate the safety and performance of the BioMimics 3D Stent System in the treatment of symptomatic SFA/proximal popliteal disease.
- Trial name
- Mimics (NCT02163863)
- Testing
- Femoropopliteal stenting
- Where
- Germany
- Volunteers
- 86 people
- Sponsor
- Veryan Medical Ltd.
Cancer
Suberoylanilide Hydroxamic Acid in Treating Patients With Advanced Cancer
RATIONALE: Suberoylanilide hydroxamic acid may stop the growth of cancer cells by blocking the enzymes necessary for cancer cell growth.
- Trial name
- NCT00045006
- Testing
- vorinostat
- Where
- United States
- Sponsor
- Memorial Sloan Kettering Cancer Center
Myocardial Infarction, Unstable Angina Pectoris, Sudden Cardiac Death, Stroke, Peripheral Artery Disease
Protective Effect of EPA on Cardiovascular Events
The purpose of this study was to test the hypothesis that the long-term use of highly (>98%) purified EPA, in addition to HMG-CoA reductase inhibitor (statin), would be more effective than statin alone in preventing…
- Trial name
- NCT00231738
- Testing
- Eicosapentaenoic acid ethyl ester(EPADEL Capsule 300 TM)
- Where
- Japan
- Volunteers
- 18,000 people
- Sponsor
- Kobe University
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